Aspirin-triggered 15-epi-lipoxin A4 predicts cyclooxygenase-2 in the lungs of LPS-treated mice but not in the circulation: Implications for a clinical test

FASEB Journal

Volumn 27, Issue 10, 2013, Pages 3938-3946

  Kirkby, Nicholas S ^a,b   Chan, Melissa V ^b   Lundberg, Martina H ^b   Massey, Karen A ^c   Edmands, William M B ^a   Mackenzie, Louise S ^a,d   Holmes, Elaine ^a   Nicolaou, Anna ^c   Warner, Timothy D ^b   Mitchell, Jane A ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY OF BRADFORD   (United Kingdom)

^d UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

Author keywords

15 HETE; COX 2 biomarker; Nonsteroidal anti inflammatory drugs; Vascular inflammation

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; LIPOPOLYSACCHARIDE; LIPOXIN A; BIOLOGICAL MARKER; LIPOXIN; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; FATTY ACID BLOOD LEVEL; FEMALE; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; LUNG; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; RAT; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; TOXICITY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; BIOLOGICAL MARKERS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; LIPOPOLYSACCHARIDES; LIPOXINS; LUNG; MICE;

EID: 84885130079     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-215533     Document Type: Article

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