Fanconi anemia complementation group A (FANCA) localizes to centrosomes and functions in the maintenance of centrosome integrity

International Journal of Biochemistry and Cell Biology

Volumn 45, Issue 9, 2013, Pages 1953-1961

  Kim, Sunshin ^a   Hwang, Soo Kyung ^a   Lee, Mihee ^a   Kwak, Heejin ^a   Son, Kook ^a   Yang, Jiha ^a   Kim, Sung Hak ^a   Lee, Chang Hun ^a  

^a National Cancer Center   (South Korea)

Author keywords

Centrosome; FANCA; Nek2; Phosphorylation; Protein interaction

Indexed keywords

FANCONI ANEMIA GROUP A PROTEIN; NOCODAZOLE; PHOSPHOSPECIFIC ANTIBODY;

CENTROSOME; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MICROTUBULE; MITOSIS INHIBITION; OSTEOSARCOMA CELL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVIEW;

CENTROSOME; FANCA; NEK2; PHOSPHORYLATION; PROTEIN INTERACTION;

CELL CYCLE PROTEINS; CELL LINE, TUMOR; CENTROSOME; FANCONI ANEMIA COMPLEMENTATION GROUP A PROTEIN; HEK293 CELLS; HUMANS; MITOSIS; MUTAGENESIS, SITE-DIRECTED; NOCODAZOLE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 84885124851     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2013.06.012     Document Type: Article

References (38)

1. Bahmanyar S, Kaplan DD, Deluca J.G., Giddings TH Jr, O'Toole ET, Winey M, et al Beta-catenin is a Nek2 substrate involved in centrosome separation. Genes & Development 2008; 22:91-105.
2. Christianson TA, Bagby GC FANCA protein binds FANCG proteins in an intracellular complex. Blood 2000; 95:725-6. (Pubitemid 30041696)
3. Collis SJ, Ciccia A, Deans AJ, Horejsi Z, Martin JS, Maslen SL, et al. FANCMand FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex. Molecular Cell 2008; 32:313-24.
4. Ferrer M, Rodriguez JA, Spierings E.A., de Winter JP, Giaccone G, Kruyt FA Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export. Human Molecular Genetics 2005; 14:1271-81. (Pubitemid 40744487)
5. Fry AM, Meraldi P, Nigg EA A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. EMBO Journal 1998; 17:470-81. (Pubitemid 28045488)
6. Garcia-Higuera I., Kuang Y, Denham J., D'Andrea AD. The fanconi anemia proteins FANCA and FANCG stabilize each other and promote the nuclear accumulation of the Fanconi anemia complex. Blood 2000; 96: 3224-30.
7. Garcia-Higuera I., Taniguchi T, Ganesan S., Meyn MS, Timmers C, Hejna J, et al. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Molecular Cell 2001; 7:249-62. (Pubitemid 32206493)
8. Hames RS, Crookes RE, Straatman K.R., Merdes A., Hayes MJ, Faragher AJ, et al Dynamic recruitment of Nek2 kinase to the centrosome involves microtubules, PCM-1, and localized proteasomal degradation. Molecular Biology of the Cell 2005; 16:1711-24. (Pubitemid 40471942)
9. Hsu LC, White RL BRCA1 is associated with the centrosome during mitosis. Proceedings of the National Academy of Sciences of the United States of America 1998; 95:12983-8. (Pubitemid 28509510)
10. Joenje H, Patel KJ The emerging genetic and molecular basis of Fanconi anaemia. Nature Reviews Genetics 2001; 2:446-57. (Pubitemid 33673411)
11. Kim H, D'Andrea AD. Regulation of DNA cross-link repair by the Fanconi ane-mia/BRCA pathway. Genes & Development 2012; 26:1393-408.
12. Ko MJ, Murata K, Hwang D.S., Parvin JD Inhibition of BRCA1 in breast cell lines causes the centrosome duplication cycle to be disconnected from the cell cycle. Oncogene 2006; 25:298-303. (Pubitemid 43083691)
13. Kwak HJ, Kim SH, Yoo H.G., Park SH, Lee CH Jun activation domain-binding protein 1 is required for mitotic checkpoint activation via its involvement in hyper-phosphorylation of 53BP1. Journal of Cancer Research and Clinical Oncology 2005; 131:789-96. (Pubitemid 41627628)
14. Latt SA, Kaiser TN, Lojewski A, Dougherty C., Juergens L, Brefach S, et al Cytogenetic and flow cytometric studies of cells from patients with Fanconi's anemia. Cytogenetics and Cell Genetics 1982; 33:133-8. (Pubitemid 12038936)
15. Levran O, Doggett NA, Auerbach AD Identification of Alu-mediated deletions in the Fanconi anemia gene FAA. Human Mutation 1998; 12:145-52. (Pubitemid 28384586)
16. Li J, Sejas DP, Zhang X, Qiu Y., Nattamai KJ, Rani R, et al TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells. Journal of Clinical Investigation 2007; 117:3283-95. (Pubitemid 350096985)
17. Lu KP, Kemp BE, Means AR Identification of substrate specificity determinants for the cell cycle-regulated NIMA protein kinase. Journal of Biological Chemistry 1994; 269:6603-7.
18. Moniz L, Dutt P, Haider N., Stambolic V. Nek family of kinases in cell cycle, checkpoint control and cancer. Cell Division 2011; 6:18.
19. Nakanishi A, Han X, Saito H., Taguchi K, Ohta Y, Imajoh-Ohmi S, et al Interference with BRCA2, which localizes to the centrosome during S and early M phase, leads to abnormal nuclear division. Biochemical and Biophysical Research Communications 2007; 355:34-40. (Pubitemid 46273362)
20. Nakanishi K, Taniguchi T, Ranganathan V, New HV, Moreau LA, Stotsky M, et al. Interaction of FANCD2 and NBS1 in the DNA damage response. Nature Cell Biology 2002; 4:913-20. (Pubitemid 35469420)
21. Otsuki T, Kajigaya S, Ozawa K, Liu JM. SNX5, a new member of the sorting nexin family, binds to the Fanconi anemia complementation group A protein. Biochemical and Biophysical Research Communications 1999; 265:630-5.
22. Pagano G, Youssoufian H. Fanconi anaemia proteins: major roles in cell protection against oxidative damage. BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology 2003; 25:589-95. (Pubitemid 36705510)
23. Pang Q, Andreassen PR Fanconi anemia proteins and endogenous stresses. Mutation Research 2009; 668:42-53.
24. Parvin JD, Sankaran S. The BRCA1 E3 ubiquitin ligase controls centrosome dynamics. Cell Cycle 2006; 5:1946-50. (Pubitemid 44435300)
25. Paweletz N, Mazia D, Finze EM The centrosome cycle in the mitotic cycle of sea urchin eggs. Experimental Cell Research 1984; 152:47-65. (Pubitemid 14143606)
26. Reuter T, Herterich S, Bernhard O, Hoehn H, Gross HJ. Strong FANCA/FANCG but weak FANCA/FANCC interaction in the yeast 2-hybrid system. Blood 2000; 95:719-20. (Pubitemid 30041693)
27. Sankaran S, Parvin JD Centrosome function in normal and tumor cells. Journal of Cellular Biochemistry 2006; 99:1240-50.
28. Sankaran S, Starita LM, Groen A.C., Ko MJ, Parvin JD Centrosomal microtubule nucleation activity is inhibited by BRCA1-dependent ubiquitination. Molecular and Cellular Biology 2005; 25:8656-68. (Pubitemid 41369184)
29. Sato N, Mizumoto K, Nakamura M., Tanaka M. Radiation-induced centrosome overduplication and multiple mitotic spindles in human tumor cells. Experimental Cell Research 2000; 255:321-6. (Pubitemid 30143865)
30. Shimada M, Komatsu K. Emerging connection between centrosome and DNA repair machinery. Journal of Radiation Research 2009; 50:295-301.
31. Shimada M, Sagae R, Kobayashi J., Habu T, Komatsu K. Inactivation of the Nijmegen breakage syndrome gene leads to excess centrosome duplication via the ATR/BRCA1 pathway. Cancer Research 2009; 69:1768-75.
32. Starita LM, Machida Y, Sankaran S., Elias JE, Griffin K, Schlegel BP, et al BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number. Molecular and Cellular Biology 2004; 24:8457-66. (Pubitemid 39245068)
33. Taniguchi T, Garcia-Higuera I, Andreassen P.R., Gregory RC, Grompe M, D'Andrea AD. S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood 2002a; 100:2414-20.
34. Taniguchi T, Garcia-Higuera I, Xu B., Andreassen PR, Gregory RC, Kim ST, et al Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. Cell 2002b; 109:459-72. (Pubitemid 34564473)
35. Valeri A, Alonso-Ferrero ME, Rio P., Pujol MR, Casado JA, Perez L, et al Bcr/Abl interferes with the Fanconi anemia/BRCA pathway: implications in the chromosomal instability of chronic myeloid leukemia cells. PloS ONE 2010; 5:e15525.
36. Yamashita T, Nakahata T. Current knowledge on the pathophysiology of Fanconi anemia: from genes to phenotypes. International Journal of Hematology 2001; 74:33-41. (Pubitemid 33798749)
37. Yang YG, Herceg Z, Nakanishi K., Demuth I, Piccoli C, Michelon J., et al The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells. Carcinogenesis 2005; 26:1731-40. (Pubitemid 41487988)
38. Zhang S, Hemmerich P, Grosse F. Centrosomal localization of DNA damage checkpoint proteins. Journal of Cellular Biochemistry 2007; 101:451-65. (Pubitemid 46698878)