Starch-based microspheres for sustained-release of curcumin: Preparation and cytotoxic effect on tumor cells

Carbohydrate Polymers

Volumn 98, Issue 1, 2013, Pages 711-720

  Pereira, Antonio G B ^a   Fajardo, André R ^a   Nocchi, Samara ^a   Nakamura, Celso V ^a   Rubira, Adley F ^a   Muniz, Edvani C ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

Author keywords

Antitumor activity; Curcumin; Microspheres; Oral drug delivery system; Starch

Indexed keywords

CELL CULTURE; CYTOTOXICITY; DRUG PRODUCTS; PH; STARCH; TUMORS;

ANOMALOUS TRANSPORT; ANTI-TUMOR ACTIVITIES; CURCUMIN; CYTOTOXICITY ASSAYS; N-METHYLENEBISACRYLAMIDE; ORAL DRUG DELIVERY SYSTEM; STARCH MICROSPHERES; SUSTAINED RELEASE;

MICROSPHERES;

ACRYLAMIDE DERIVATIVE; ANTINEOPLASTIC AGENT; CURCUMIN; DRUG CARRIER; MICROSPHERE; N,N' METHYLENEBISACRYLAMIDE; N,N'-METHYLENEBISACRYLAMIDE; STARCH;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN CACO 2; CELL STRAIN HCT116; CHEMISTRY; DELAYED RELEASE FORMULATION; HUMAN; ORAL DRUG DELIVERY SYSTEM;

ANTITUMOR ACTIVITY; CURCUMIN; MICROSPHERES; ORAL DRUG DELIVERY SYSTEM; STARCH;

ACRYLAMIDES; ANTINEOPLASTIC AGENTS; CACO-2 CELLS; CURCUMIN; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; HCT116 CELLS; HUMANS; MICROSPHERES; STARCH;

EID: 84885121728     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2013.06.013     Document Type: Article

References (59)

1. Anand, P., Kunnumakkara, A. B., Newman, R. A., & Aggarwal, B. B. (2007). Bioavailability of curcumin: Problems and promises. Molecular Pharmaceutics, 4(6), 807-818.
2. Anand, P., Kunnumakkara, A. B., Sundaram, C., Harikumar, K. B., Tharakan, S. T., Lai, O. S., et al. (2008). Cancer is a preventable disease that requires major lifestyle changes. Pharmaceutical Research, 25(9), 2097-2116.
3. Anand, P., Sundaram, C., Jhurani, S., Kunnumakkara, A. B., & Aggarwal, B. B. (2008). Curcumin and cancer: an "old-age" disease with an "age-old" solution. Cancer Letters, 267(1), 133-164.
4. Angellier, H., Molina-Boisseau, S., Dole, P., & Dufresne, A. (2006). Thermoplastic starch-waxy maize starch nanocrystals nanocomposites. Biomacromolecules, 7(2), 531-539.
5. Cabrespine-Faugeras, A., Bayet-Robert, M., Bay, J. O., Chollet, P., & Barthomeuf, C. (2010). Possible benefits of curcumin regimen in combination with taxane chemotherapy for hormone-refractory prostate cancer treatment. Nutrition and Cancer, 62(2), 148-153.
6. Chen, L., Li, X., Pang, Y., Li, L., Zhang, X., & Yu, L. (2007). Resistant starch as a carrier for oral colon-targeting drug matrix system. Journal of Materials Science: Materials in Medicine, 18(11), 2199-2203. (Pubitemid 350167370)
7. Colombo, P., Bettini, R., Santi, P., & Peppas, N. A. (2000). Swellable matrices for controlled drug delivery: gel-layer behaviour, mechanisms and optimal performance. Pharmaceutical Science & Technology Today, 3(6), 198-204. (Pubitemid 30364933)
8. Costa, D., Valente, A. J. M., Miguel, M. G., & Queiroz, J. (2012). Plasmid DNA microgels for a therapeutical strategy combining the delivery of genes and anticancer drugs. Macromolecular Bioscience, 12(9), 1243-1252.
9. Costa, E., De-Carvalho, J., Casimiro, T., Da Silva, C. L., Cidade, M. T., & Aguiar-Ricardo, A. (2011). Tailoring thermoresponsive microbeads in supercritical carbon dioxide for biomedical applications. Journal of Supercritical Fluids, 56(3), 292-298.
10. Desai, S. J., Singh, P., Simonelli, A. P., & Higuchi, W. I. (1966). Investigation of factors influencing release of solid drug dispersed in inert matrices III. Quantitative studies involving the polyethylene plastic matrix. Journal of Pharmaceutical Sciences, 55(11), 1230-1234.
11. Gautam Singhvi, M. S. (2011). Review: In-vitro drug release characterization models. International Journal of Pharmaceutical Studies and Research, 2(1), 77-84.
12. Guilherme, M. R., Oliveira, R. S., Mauricio, M. R., Cellet, T. S. P., Pereira, G. M., Kunita, M. H., et al. (2012). Albumin release from a brain-resembling superabsorbent magnetic hydrogel based on starch. Soft Matter, 8(24), 6629-6637.
13. Guilherme, M. R., Reis, A. V., Takahashi, S. H., Rubira, A. F., Feitosa, J. P. A., & Muniz, E. C. (2005). Synthesis of a novel superabsorbent hydrogel by copolymerization of acrylamide and cashew gum modified with glycidyl methacrylate. Carbohydrate Polymers, 61(4), 464-471. (Pubitemid 41277096)
14. Hedin, J., Östlund, A., & Nydén, M. (2010). UV induced cross-linking of starch modified with glycidyl methacrylate. Carbohydrate Polymers, 79(3), 606-613.
15. Huang, J., Schols, H. A., Klaver, R., Jin, Z., & Voragen, A. G. J. (2007). Acetyl substitution patterns of amylose and amylopectin populations in cowpea starch modified with acetic anhydride and vinyl acetate. Carbohydrate Polymers, 67(4), 542-550. (Pubitemid 46097086)
16. Jain, A., Gupta, Y., & Jain, S. K. (2007). Perspectives of biodegradable natural polysaccharides for site-specific drug delivery to the colon. Journal of Pharmacy and Pharmaceutical Sciences, 10(1), 86-128. (Pubitemid 46692379)
17. Johnson, J. J., & Mukhtar, H. (2007). Curcumin for chemoprevention of colon cancer. Cancer Letters, 255(2), 170-181. (Pubitemid 47268637)
18. Josephine Leno Jenita, J., Wilson, Y. M., & Premakumari KB, B. (2012). Formulation and evaluation of microparticles containing curcumin for colorectal cancer. Journal of Drug Delivery & Therapeutics, 2(3), 125-128.
19. Kakkar, V., Singh, S., Singla, D., & Kaur, I. P. (2011). Exploring solid lipid nanoparticles to enhance the oral bioavailability of curcumin. Molecular Nutrition & Food Research, 55(3), 495-503.
20. Kim, C. H., Cho, K. Y., & Park, J. K. (2001). Reactive blends of gelatinized starch and polycaprolactone-g-glycidyl methacrylate. Journal of Applied Polymer Science, 81(6), 1507-1516. (Pubitemid 32576498)
21. Kizil, R., Irudayaraj, J., & Seetharaman, K. (2002). Characterization of irradiated starches by using FT-Raman and FTIR spectroscopy. Journal of Agricultural and Food Chemistry, 50(14), 3912-3918. (Pubitemid 34734289)
22. Korsmeyer, R. W., Gurny, R., Doelker, E., Buri, P., & Peppas, N. A. (1983). Mechanisms of solute release from porous hydrophilic polymers. International Journal of Pharmaceutics, 15(1), 25-35. (Pubitemid 13092121)
23. Leopold, C. S., & Eikeler, D. (2000). Basic coating polymers for the colon-specific drag delivery in inflammatory bowel disease. Drug Development and Industrial Pharmacy, 26(12), 1239-1246. (Pubitemid 32037420)
24. Li, F., Li, X., & Li, B. (2011). Preparation of magnetic polylactic acid microspheres and investigation of its releasing property for loading curcumin. Journal of Magnetism and Magnetic Materials, 323(22), 2770-2775.
25. Ma, Z., Haddadi, A., Molavi, O., Lavasanifar, A., Lai, R., & Samuel, J. (2008). Micelles of poly(ethylene oxide)-b-poly(caprolactone) as vehicles for the solubilization, stabilization, and controlled delivery of curcumin. Journal of Biomedical Materials Research Part A, 86A(2), 300-310.
26. Mandal, B. B., Kapoor, S., & Kundu, S. C. (2009). Silk fibroin/polyacrylamide semiinterpenetrating network hydrogels for controlled drug release. Biomaterials, 30(14), 2826-2836.
27. Mandeville, J.-S., Froehlich, E., & Tajmir-Riahi, H. A. (2009). Study of curcumin and genistein interactions with human serum albumin. Journal of Pharmaceutical and Biomedical Analysis, 49(2), 468-474.
28. Meng, L. M., Yuan, Y. C., Rong, M. Z., & Zhang, M. Q. (2010). A dual mechanism singlecomponent self-healing strategy for polymers. Journal of Materials Chemistry, 20(29), 6030-6038.
29. Möckel, J., & Lippold, B. (1993). Zero-order drug release from hydrocolloid matrices. Pharmaceutical Research, 10(7), 1066-1070. (Pubitemid 23211433)
30. Mohanty, C., & Sahoo, S. K. (2010). The in vitro stability and in vivo pharmacokinetics of curcumin prepared as an aqueous nanoparticulate formulation. Biomaterials, 31(25), 6597-6611.
31. Namazi, H., & Dadkhah, A. (2010). Convenient method for preparation of hydrophobically modified starch nanocrystals with using fatty acids. Carbohydrate Polymers, 79(3), 731-737.
32. Noack, A., Oidtmann, J., Kutza, J., & Mäder, K. (2012). In vitro digestion of curcuminoid-loaded lipid nanoparticles. Journal of Nanoparticle Research, 14(9).
33. Onofre, F. O., & Wang, Y. J. (2010). Sustained release properties of crosslinked and substituted starches. Journal of Applied Polymer Science, 117(3), 1558-1565.
34. Skehan, P., Scudeiro, R. S. D., Monks, A., McMahon, J., Vistica, D., Warren, J. T., et al. (1990). New colorimetric cytotoxicity assay for anticancer-drug screening. Journal of National Cancer Institute, 82(13), 1107-1112. (Pubitemid 20213250)
35. Pereira, A. G. B., Gouveia, R. F., de Carvalho, G. M., Rubira, A. F., & Muniz, E. C. (2009). Polymer blends based on PEO and starch: Miscibility and spherulite growth rate evaluated through DSC and optical microscopy. Materials Science and Engineering C, 29(2), 499-504.
36. Radhakrishna Pillai, G., Srivastava, A. S., Hassanein, T. I., Chauhan, D. P., & Carrier, E. (2004). Induction of apoptosis in human lung cancer cells by curcumin. Cancer Letters, 208(2), 163-170. (Pubitemid 38624157)
37. Reis, A. V., Fajardo, A. R., Schuquel, I. T. A., Guilherme, M. R., Vidotti, G. J., Rubira, A. F., et al. (2009). Reaction of glycidyl methacrylate at the hydroxyl and carboxylic groups of poly(vinyl alcohol) and poly(acrylic acid): Is this reaction mechanism still unclear? The Journal of Organic Chemistry, 74(10), 3750-3757.
38. Reis, A. V., Guilherme, M. R., Moia, T. A., Mattoso, L. H. C., Muniz, E. C., & Tambourgi, E. B. (2008). Synthesis and characterization of a starch-modified hydrogel as potential carrier for drug delivery system. Journal of Polymer Science. Part A: Polymer Chemistry, 46(7), 2567-2574. (Pubitemid 351430176)
39. Ritger, P. L., & Peppas, N. A. (1987). A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. Journal of Controlled Release, 5(1), 23-36. (Pubitemid 17106643)
40. Riyajan, S. A., Sasithornsonti, Y., & Phinyocheep, P. (2012). Green natural rubberg- modified starch for controlling urea release. Carbohydrate Polymers, 89(1), 251-258.
41. Rodrigues, F. A., Fajardo, A., Pereira, A. B., Ricardo, N. P. S., Feitosa, J. A., & Muniz, E. (2012). Chitosan-graft-poly(acrylic acid)/rice husk ash based superabsorbent hydrogel composite: preparation and characterization. Journal of Polymer Research, 19(12), 1-10.
42. Sahu, A., Bora, U., Kasoju, N., & Goswami, P. (2008). Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)-palmitate nanocarrier for curcumin delivery to cancer cells. Acta Biomaterialia, 4(6), 1752-1761.
43. Saito, N., Murakami, N., Takahashi, J., Horiuchi, H., Ota, H., Kato, H., et al. (2005). Synthetic biodegradable polymers as drug delivery systems for bone morphogenetic proteins. Advanced Drug Delivery Reviews, 57(7), 1037-1048. (Pubitemid 40692290)
44. Shaikh, J., Ankola, D. D., Beniwal, V., Singh, D., & Kumar, M. N. V. R. (2009). Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. European Journal of Pharmaceutical Sciences, 37(3-4), 223-230.
45. Sharma, R. A., Gescher, A. J., & Steward, W. P. (2005). Curcumin: the story so far. European Journal of Cancer, 41(13), 1955-1968. (Pubitemid 41557681)
46. Shen, L., & Ji, H. F. (2012). The pharmacology of curcumin: Is it the degradation products? Trends in Molecular Medicine, 18(3), 138-144.
47. Singh, P., Desai, S. J., Simonelli, A. P., & Higuchi, W. I. (1967). Release rates of solid drug mixtures dispersed in inert matrices. I. Noninteracting drug mixtures. Journal of Pharmaceutical Sciences, 56(12), 1542-1547.
48. Song, L., Shen, Y., Hou, J., Lei, L., Guo, S., & Qian, C. (2011). Polymeric micelles for parenteral delivery of curcumin: preparation, characterization and in vitro evaluation. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 390(1-3), 25-32.
49. Spagnol, C., Rodrigues, F. A., Pereira, A. B., Fajardo, A., Rubira, A., & Muniz, E. (2012). Superabsorbent hydrogel nanocomposites based on starch-g-poly(sodium acrylate) matrix filled with cellulose nanowhiskers. Cellulose, 19(4), 1225-1237.
50. Spagnol, C., Rodrigues, F. H. A., Neto, A. G. V. C., Pereira, A. G. B., Fajardo, A. R., Radovanovic, E., et al. (2012). Nanocomposites based on poly(acrylamide-coacrylate) and cellulose nanowhiskers. European Polymer Journal, 48(3), 454-463.
51. Sun, A., Shoji, M., Lu, Y. J., Liotta, D. C., & Snyder, J. P. (2006). Synthesis of EF24- tripeptide chloromethyl ketone: A novel curcumin-related anticancer drug delivery system. Journal of Medicinal Chemistry, 49(11), 3153-3158. (Pubitemid 43830514)
52. Sun, M., Zhao, L., Guo, C., Cao, F., Chen, H., Zhao, L., et al. (2012). Evaluation of an oral carrier system in rats: Bioavailability and gastrointestinal absorption properties of curcumin encapsulated PBCA nanoparticles. Journal of Nanoparticle Research, 14.(2).
53. Tang, H., Murphy, C. J., Zhang, B., Shen, Y., Van Kirk, E. A., Murdoch, W. J., et al. (2010). Curcumin polymers as anticancer conjugates. Biomaterials, 31(27), 7139-7149.
54. Thompson, M. T., Berg, M. C., Tobias, I. S., Lichter, J. A., Rubner, M. F., & Van Vliet, K. J. (2006). Biochemical functionalization of polymeric cell substrata can alter mechanical compliance. Biomacromolecules, 7(6), 1990-1995. (Pubitemid 43985123)
55. Tønnesen, H. H., Másson, M., & Loftsson, T. (2002). Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: Solubility, chemical and photochemical stability. International Journal of Pharmaceutics, 244(1-2), 127-135. (Pubitemid 35245453)
56. Vemula, P. K., Cruikshank, G. A., Karp, J. M., & John, G. (2009). Self-assembled prodrugs: An enzymatically triggered drug-delivery platform. Biomaterials, 30(3), 383-393.
57. Wang, Y. J., Pan, M. H., Cheng, A. L., Lin, L. I., Ho, Y. S., Hsieh, C. Y., et al. (1997). Stability of curcumin in buffer solutions and characterization of its degradation products. Journal of Pharmaceutical and Biomedical Analysis, 15(12), 1867-1876.
58. Xu, Y., Ding, W., Liu, J., Li, Y., Kennedy, J. F., Gu, Q., et al. (2010). Preparation and characterization of organic-soluble acetylated starch nanocrystals. Carbohydrate Polymers, 80(4), 1078-1084.
59. Zhang, B., Gong, H., Lü, S., Ni, B., Liu, M., Gao, C., et al. (2012). Synthesis and characterization of carboxymethyl potato starch and its application in reactive dye printing. International Journal of Biological Macromolecules, 51(4), 668-674.