Obstructive sleep apnea syndrome, vascular pathology, endothelial function and endothelial cells and circulating microparticles

Archives of Medical Research

Volumn 44, Issue 6, 2013, Pages 409-414

  Stiefel, Pablo ^a   Sánchez Armengol, Maria Angeles ^b   Villar, José ^a   Vallejo Vaz, Antonio ^a   Moreno Luna, Rafael ^a   Capote, Francisco ^b  

^a UNIVERSITY OF SEVILLE   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

Author keywords

Endothelial cells; Endothelial dysfunction; Obstructive sleep apnea syndrome; Progenitor endothelial cells; Vascular risk

Indexed keywords

ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE;

BLOOD CLOTTING DISORDER; CARDIOVASCULAR RISK; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIAL PROGENITOR CELL; ENDOTHELIUM; ENDOTHELIUM CELL; HUMAN; HYPERTENSION; HYPOXEMIA; INFLAMMATION; LEUKOCYTE; LIPID METABOLISM; LIPID PEROXIDATION; MEMBRANE MICROPARTICLE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; REVIEW; SLEEP DISORDERED BREATHING; VASCULAR DISEASE;

ENDOTHELIAL CELLS; ENDOTHELIAL DYSFUNCTION; OBSTRUCTIVE SLEEP APNEA SYNDROME; PROGENITOR ENDOTHELIAL CELLS; VASCULAR RISK;

ANOXIA; CARDIOVASCULAR DISEASES; CAUSALITY; CELL-DERIVED MICROPARTICLES; COMORBIDITY; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HEMATOPOIETIC STEM CELLS; HUMANS; INFLAMMATION; LIPID PEROXIDATION; OXIDATIVE STRESS; RISK FACTORS; SLEEP APNEA, OBSTRUCTIVE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84885102238     PISSN: 01884409     EISSN: 18735487     Source Type: Journal    
DOI: 10.1016/j.arcmed.2013.08.005     Document Type: Review

References (85)

1. Young T., Palta M., Dempsey J., et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993, 328:1230-1235.
2. Duran J., Esnaola S., Rubio R., et al. Obstructive sleep apnea-hypopnea and related clinical features in a population-based sample of subjects aged 30-70 year. Am J Respir Crit Care Med 2001, 163:685-689.
3. Nieto F.J., Young T.B., Lind B.K., et al. Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study. JAMA 2000, 283:1829-1836.
4. Peppard P.E., Young T., Palta M., et al. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 2000, 342:1378-1384.
5. Onusko E. Diagnosing secondary hypertension. Am Fam Physician 2003, 67:67-74.
6. Barbé F., Durán-Cantolla J., Capote F., et al. Long-term effect of continuous positive airway pressure in hypertensive patients with sleep apnea. Am J Respir Crit Care Med 2010, 181:718-726.
7. Shahar E., Whitney C.W., Redline S., et al. Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med 2001, 163:5-6.
8. Marin J.M., Carrizo S.J., Vicente E., et al. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without continuous positive airway pressure: an observational study. Lancet 2005, 365:1046-1053.
9. Redline S., Yenokyan G., Gottlieb D.J., et al. Obstructive sleep apnea-hypopnea and incident stroke: the Sleep Heart Health Study. Am J Respir Crit Care Med 2010, 182:269-277.
10. Gottlieb D.J., Yenokyan G., Newman A.B., et al. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the Sleep Heart Health Study. Circulation 2010, 122:352-360.
11. Gami A.S., Hodge D.O., Herges R.M., et al. Obstructive sleep apnea, obesity and the risk of incident atrial fibrillation. J Am Coll Cardiol 2007, 49:565-571.
12. Baguet J.P., Barone-Rochette G., Tamisier R., et al. Mechanisms of cardiac dysfunction in obstructive sleep apnea. Nat Rev Cardiol 2012, 9:679-688.
13. Kohler M., Stradling J.R. Mechanisms of vascular damage in obstructive sleep apnea. Nat Rev Cardiol 2010, 7:677-685.
14. Young T., Finn L., Peppard P.E., et al. Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin Sleep Cohort. Sleep 2008, 31:1071-1078.
15. Punjabi N.M., Caffo B.S., Goodwin J.L., et al. Sleep disordered breathing and mortality: a prospective cohort study. PLoS Med 2009, 6:e1000132.
16. Fletcher E.C. Effect of episodic hypoxia on sympathetic activity and blood pressure. Respir Physiol 2000, 119:189-197.
17. Coughlin S.R., Mawdsley L., Mugarza J.A., et al. Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome. Eur Heart J 2004, 25:735-741.
18. Punjabi N.M., Shahar E., Redline S., et al. Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study. Am J Epidemiol 2004, 160:521-530.
19. Haas D.C., Foster G.L., Nieto F.J., et al. Age-dependent associations between sleep-disordered breathing and hypertension: importance of discriminating between systolic/diastolic hypertension and isolated systolic hypertension in the Sleep Heart Health Study. Circulation 2005, 111:614-621.
20. Newman A.B., Nieto F.J., Guidry U., et al. Relation of sleep-disordered breathing to cardiovascular disease risk factors: the Sleep Heart Health Study. Am J Epidemiol 2001, 154:50-59.
21. Marin J.M., Agusti A., Villar I., et al. Association between treated and untreated obstructive sleep apnea and risk of hypertension. JAMA 2012, 307:2169-2176.
22. Barbé F., Durán-Cantolla J., Sánchez-de-la-Torre M., et al. Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial. JAMA 2012, 307:2161-2168.
23. Lp M.S., Tse H.F., Lam B., et al. Endothelial function in obstructive sleep apnea and response to treatment. Am J Respir Crit Care Med 2004, 169:348-353.
24. Nieto F.J., Herrington D.M., Redline S., et al. Sleep apnea and markers of vascular endothelial function in a large community sample of older adults. Am J Respir Crit Care Med 2004, 169:354-360.
25. Budhiraja R., Tuder R.M., Hassoun P.M. Endothelial dysfunction in pulmonary hypertension. Circulation 2004, 109:159-165.
26. Budhiraja R., Quan S.F. Sleep-disordered breathing and hypertension. J Clin Sleep Med 2005, 11:401-404.
27. Budhiraja R., Quan S.F. Sleep-disordered breathing and cardiovascular health. Curr Opin Pulm Med 2005, 11:501-506.
28. Lattimore J.L., Wilcox I., Skilton M., et al. Treatment of obstructive sleep apnea leads to improved microvascular endothelial function in the systemic circulation. Thorax 2006, 61:491-495.
29. Grebe M., Eisele H.J., Weissmann N., et al. Antioxidant vitamin C improves endothelial function in obstructive sleep apnea. Am J Respir Crit Care Med 2006, 173:897-901.
30. Kato M., Roberts-Thomson P., Phillips B.G., et al. Impairment of endothelium-dependent vasodilation of resistance vessels in patients with obstructive sleep apnea. Circulation 2000, 102:2607-2610.
31. Lavie L. Obstructive sleep apnea syndrome-an oxidative stress disorder. Sleep Med Rev 2003, 7:35-51.
32. Schulz R., Mahmoudi S., Hattar K., et al. Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea. Impact of continuous positive airway pressure therapy. Am J Respir Crit Care Med 2000, 162:566-570.
33. Dyugovskaya L., Lavie P., Lavie L. Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients. Am J Respir Crit Care Med 2002, 165:934-939.
34. Nedeljkovic Z.S., Gokce N., Loscalzo J. Mechanisms of oxidative stress and vascular dysfunction. Postgrad Med J 2003, 79:195-199. quiz 198-200.
35. Lavie L., Vishnevsky A., Lavie P. Evidence for lipid peroxidation in obstructive sleep apnea. Sleep 2004, 27:123-128.
36. Ohga E., Nagase T., Tomita T., et al. Increased levels of circulating ICAM-1, VCAM-1, and L-selectin in obstructive sleep apnea syndrome. J Appl Physiol 1999, 87:10-14.
37. El-Solh A.A., Mador M.J., Sikka P., et al. Adhesion molecules in patients with coronary artery disease and moderate-to-severe obstructive sleep apnea. Chest 2002, 121:1541-1547.
38. Luc G., Bard J.M., Juhan-Vague I., et al. C-reactive protein, interleukin-6, and fibrinogen as predictors of coronary heart disease: the PRIME Study. Arterioscler Thromb Vasc Biol 2003, 23:1255-1261.
39. Mehra R., Storfer-Isser A., Kirchner H.L., et al. Soluble interleukin 6 receptor: a novel marker of moderate to severe sleep-related breathing disorder. Arch Intern Med 2006, 166:1725-1731.
40. Shamsuzzaman A.S., Winnicki M., Lanfranchi P., et al. Elevated C-reactive protein in patients with obstructive sleep apnea. Circulation 2002, 105:2462-2464.
41. Larkin E.K., Rosen C.L., Kirchner H.L., et al. Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration. Circulation 2005, 111:1978-1984.
42. Yokoe T., Minoguchi K., Matsuo H., et al. Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure. Circulation 2003, 107:1129-1134.
43. Fichtlscherer S., Rosenberger G., Walter D.H., et al. Elevated C-reactive protein levels and impaired endothelial vasoreactivity in patients with coronary artery disease. Circulation 2000, 102:1000-1006.
44. Jelic S., Padeletti M., Kawut S.M., et al. Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea. Circulation 2008, 117:2270-2278.
45. Jelic S., Lederer D.J., Adams T., et al. Vascular inflammation in obesity and sleep apnea. Circulation 2010, 121:1014-1021.
46. Bokinsky G., Miller M., Ault K., et al. Spontaneous platelet activation and aggregation during obstructive sleep apnea and its response to therapy with nasal continuous positive airway pressure. A preliminary investigation. Chest 1995, 108:625-630.
47. von Kanel R., Dimsdale J.E. Hemostatic alterations in patients with obstructive sleep apnea and the implications for cardiovascular disease. Chest 2003, 124:1956-1967.
48. Wessendorf T.E., Thilmann A.F., Wang Y.M., et al. Fibrinogen levels and obstructive sleep apnea in ischemic stroke. Am J Respir Crit Care Med 2000, 162:2039-2042.
49. Nobili L., Schiavi G., Bozano E., et al. Morning increase of whole blood viscosity in obstructive sleep apnea syndrome. Clin Hemorheol Microcirc 2000, 22:21-27.
50. Rangemark C., Hedner J.A., Carlson J.T., et al. Platelet function and fibrinolytic activity in hypertensive and normotensive sleep apnea patients. Sleep 1995, 18:188-194.
51. von Kanel R., Loredo J.S., Ancoli-Israel S., et al. Association between sleep apnea severity and blood coagulability: treatment effects of nasal continuous positive airway pressure. Sleep Breath 2006, 10:139-146.
52. Chin K., Ohi M., Kita H., et al. Effects of NCPAP therapy on fibrinogen levels in obstructive sleep apnea syndrome. Am J Respir Crit Care Med 1996, 153:1972-1976.
53. Frenette P.S., Johnson R.C., Hynes R.O., et al. Platelets roll on stimulated endothelium invivo: an interaction mediated by endothelial P-selectin. Proc Natl Acad Sci USA 1995, 92:7450-7454.
54. Ridker P.M., Buring J.E., Rifai N. Soluble P-selectin and the risk of future cardiovascular events. Circulation 2001, 103:491-495.
55. Nácher M., Serrano-Mollar A., Farré R., et al. Recurrent obstructive apneas trigger early systemic inflammation in a rat model of sleep apnea. Respir Physiol Neurobiol 2007, 155:93-96.
56. Mutin M., Canavy I., Blann A., et al. Direct evidence of endothelial injury in acute myocardial infarction and unstable angina by demonstration of circulating endothelial cells. Blood 1999, 93:2951-2958.
57. Akinnusi M.E., Laporta R., El-Solh A.A. Lectin-like oxidized low-density lipoprotein receptor-1 modulates endothelial apoptosis in obstructive sleep apnea. Chest 2011, 140:1503-1510.
58. Makin A.J., Blann A.D., Chung N.A., et al. Assessment of endothelial damage in atherosclerotic vascular disease by quantification of circulating endothelial cells. Relationship with von Willebrand factor and tissue factor. Eur Heart J 2004, 25:371-376.
59. Valgimigli M., Agnoletti L., Curello S., et al. Serum from patients with acute coronary syndromes displays a proapoptotic effect on human endothelial cells: a possible link to pan-coronary syndromes. Circulation 2003, 107:264-270.
60. El Solh A.A., Akinnusi M.E., Baddoura F.H., et al. Endothelial cell apoptosis in obstructive sleep apnea: a link to endothelial dysfunction. Am J Respir Crit Care Med 2007, 175:1186-1191.
61. Jung K.H., Chu K., Lee S.T., et al. Circulating endothelial microparticles as a marker of cerebrovascular disease. Ann Neurol 2009, 66:191-199.
62. Preston R.A., Jy W., Jimenez J.J., et al. Effects of severe hypertension on endothelial and platelet microparticles. Hypertension 2003, 41:211-217.
63. Sabatier F., Darmon P., Hugel B., et al. Type 1 and type 2 diabetic patients display different patterns of cellular microparticles. Diabetes 2002, 51:2840-2845.
64. Heiss C., Amabile N., Lee A.C., et al. Brief secondhand smoke exposure depresses endothelial progenitor cells activity and endothelial function: sustained vascular injury and blunted nitric oxide production. J Am Coll Cardiol 2008, 51:1760-1771.
65. Bernal-Mizrachi L., Jy W., Jimenez J.J., et al. High levels of circulating endothelial microparticles in patients with acute coronary syndromes. Am Heart J 2003, 145:962-970.
66. Priou P., Gagnadoux F., Tesse A., et al. Endothelial dysfunction and circulating microparticles from patients with obstructive sleep apnea. Am J Pathol 2010, 177:974-983.
67. Trzepizur W., Priou P., Paris A., et al. Nocturnal release of leukocyte-derived microparticles in males with obstructive sleep apnoea. Eur Respir J 2011, 37:1293-1295.
68. Tual-Chalot S., Fatoumata K., Priou P., et al. Circulating microparticles from patients with obstructive sleep apnea enhance vascular contraction: mandatory role of the endothelium. Am J Pathol 2012, 181:1473-1482.
69. Khakoo A.Y., Finkel T. Endothelial progenitor cells. Annu Rev Med 2005, 56:79-101.
70. Gill M., Dias S., Hattori K., et al. Vascular trauma induces rapid but transient mobilization of EGFR2+ AC133+ endothelial precursor cells. Circ Res 2001, 88:167-174.
71. Hristov M., Erl W., Weber P.C. Endothelial progenitor cells: mobilization, differentiation, and homing. Arterioscler Thromb Vasc Biol 2003, 23:1185-1189.
72. Hill J.M., Zalos G., Halcox J.P.J., et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003, 348:593-600.
73. Chen J.Z., Zhang F.R., Tao K.M., et al. Number and activity of endothelial progenitor cells from peripheral blood in patients with hypercholesterolaemia. Clin Sci 2004, 107:273-280.
74. Vasa M., Fichtlscherer S., Aicher A., et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001, 89:e1-e7.
75. Tepper O.M., Galiano R.D., Capla J.M., et al. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 2002, 106:2781-2786.
76. Murri M., García-Delgado R., Alcázar-Ramírez J., et al. Effect of CPAP on oxidative stress and circulating progenitor cell levels in sleep patients with apnea-hypopnea syndrome. Respir Care 2011, 56:1830-1836.
77. Kheirandish-Gozal L., Bhattacharjee R., Kim J., et al. Endothelial progenitor cells and vascular dysfunction in children with obstructive sleep apnea. Am J Respir Crit Care Med 2010, 182:92-97.
78. Kalka C., Masuda H., Takahashi T., et al. Vascular endothelial growth factor (165) gene transfer augments circulating endothelial progenitor cells in human subjects. Circ Res 2000, 86:1198-1202.
79. Lavie L., Kraiczi H., Hefetz A., et al. Plasma vascular endothelial growth factor in sleep apnea syndrome. Effects of nasal continuous positive air pressure treatment. Am J Respir Crit Care Med 2002, 165:1624-1628.
80. Schulz R., Hummel C., Heinemann S., et al. Serum levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea and severe nighttime hypoxia. Am J Respir Crit Care Med 2002, 165:67-70.
81. Gozal D., Lipton A.J., Jones K.L. Circulating vascular endothelial growth factor levels in patients with obstructive sleep apnea. Sleep 2002, 25:59-65.
82. Cherniack E.P. Vascular endothelial growth factor and sleep apnea: clutching at straws in the night. Respiration 2007, 74:17-18.
83. Peled N., Shitrit D., Bendayan D., et al. Association of elevated levels of vascular endothelial growth factor in obstructive sleep apnea syndrome with patient age rather than with obstructive sleep apnea syndrome severity. Respiration 2007, 74:50-55.
84. De la Peña M., Barceló A., Barbe F., et al. Endothelial function and circulating endothelial progenitor cells in patients with sleep apnea syndrome. Respiration 2008, 76:28-32.
85. Martin K., Stanchina M., Kouttab N., et al. Circulating endothelial cells and endothelial progenitor cells in obstructive sleep apnea. Lung 2008, 186:145-150.