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Volumn 43, Issue 10, 2013, Pages 945-953

New challenges and inspired answers for anticancer drug discovery and development

Author keywords

Breast medicine; GI medicine; Immunology; Lung Med; New technology instruments

Indexed keywords

ANTINEOPLASTIC AGENT; CAPECITABINE; CARBOPLATIN; CETUXIMAB; CISPLATIN; ENZYME INHIBITOR; FLUOROPYRIMIDINE; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; GIMERACIL; GIMERACIL PLUS OTERACIL POTASSIUM PLUS TEGAFUR; IRINOTECAN; OTERACIL; OXALIPLATIN; PACLITAXEL; PLACEBO; PYRIMIDINE DERIVATIVE; TAS 102; TAS 114; TAS 115; TAS 116; TAS 117; TAS 2104; TAS 2913; TAS 2985; TEGAFUR; THYMIDINE PHOSPHORYLASE INHIBITOR; TRIFLURIDINE; UFT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84885101279     PISSN: 03682811     EISSN: 14653621     Source Type: Journal    
DOI: 10.1093/jjco/hyt131     Document Type: Article
Times cited : (35)

References (37)
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    • TAS-116, a novel, orally bioavailable HSP90a/β selective inhibitor demonstrates highly potent antitumor activity in preclinical models with a favorable PK profile
    • (Abstract 291).
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    • Evolution of highly selective HSP90a/β inhibitors with unique binding mode
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    • TAS-116, a novel, orally bioavailable highly potent HSP90a/β selective inhibitor demonstrates favorable tissue distribution properties which lead to minimized ocular toxicity
    • (Abstract 290)
    • Kodama Y, Hitotsumachi H, Shibata Y, et al. TAS-116, a novel, orally bioavailable highly potent HSP90a/β selective inhibitor demonstrates favorable tissue distribution properties which lead to minimized ocular toxicity. In: 24th EORTC-NCI-AACR symposium 2012 (Abstract 290).
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