-
1
-
-
0024164649
-
Fluorouracil: Biochemistry and pharmacology
-
Pinedo, H H., and Peters, G. F. J. Fluorouracil: biochemistry and pharmacology. J. Clin. Oncol., 6: 1653-1664, 1988.
-
(1988)
J. Clin. Oncol.
, vol.6
, pp. 1653-1664
-
-
Pinedo, H.H.1
Peters, G.F.J.2
-
2
-
-
0006021329
-
Fluorinated pyrimidines and their nucleosides
-
A. C. Sartorelli and D. Johns (eds.) New York: Springer-Verlag
-
Heidelberger, C. Fluorinated pyrimidines and their nucleosides In: A. C. Sartorelli and D. Johns (eds.), Antineoplastic and Immunosuppressive Agents Handbook of Experimental Pharmacology, Vol. 38, pp 193-231, New York: Springer-Verlag, 1975
-
(1975)
Antineoplastic and Immunosuppressive Agents Handbook of Experimental Pharmacology
, vol.38
, pp. 193-231
-
-
Heidelberger, C.1
-
3
-
-
0002347343
-
Fluorinated pyrimidines and their nucleosides
-
Heidelberger, C , Dannenberg, P. V., and Moran, R. G. Fluorinated pyrimidines and their nucleosides. Adv Enzymol. Relat. Areas Mol. Biol., 54: 57-119, 1989.
-
(1989)
Adv Enzymol. Relat. Areas Mol. Biol.
, vol.54
, pp. 57-119
-
-
Heidelberger, C.1
Dannenberg, P.V.2
Moran, R.G.3
-
4
-
-
0000787521
-
The synthesis of 5-fluoropyrimidines
-
Duschinsky, R., Pleven, E., and Heidelberger, C. The synthesis of 5-fluoropyrimidines. J. Am. Chem. Soc., 79: 4559-4560, 1957.
-
(1957)
J. Am. Chem. Soc.
, vol.79
, pp. 4559-4560
-
-
Duschinsky, R.1
Pleven, E.2
Heidelberger, C.3
-
5
-
-
0023250474
-
Inhibitory effects of pyrimidine, barbituric acid and pyridine derivatives on 5-fluorouracil degradation in rat liver extract
-
Tatsumi, K., Fukushima, M., Shirasaka, T., and Fujii, S Inhibitory effects of pyrimidine, barbituric acid and pyridine derivatives on 5-fluorouracil degradation in rat liver extract. Jpn. J. Cancer Res , 78. 748-755, 1987.
-
(1987)
Jpn. J. Cancer Res
, vol.78
, pp. 748-755
-
-
Tatsumi, K.1
Fukushima, M.2
Shirasaka, T.3
Fujii, S.4
-
6
-
-
0008584931
-
Preclinical studies on S-1, a new oral tegafur plus modulators optimal molar ratio and antitumor activity
-
Shirasaka, T., Fukushima, M., Shimamoto, Y., and Kimura, K. Preclinical studies on S-1, a new oral tegafur plus modulators optimal molar ratio and antitumor activity Proc. Int. Congr. Chemother., 18. 927, 1993
-
(1993)
Proc. Int. Congr. Chemother.
, vol.18
, pp. 927
-
-
Shirasaka, T.1
Fukushima, M.2
Shimamoto, Y.3
Kimura, K.4
-
7
-
-
0027227591
-
Inhibition of oxonic acid on gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats
-
Shirasaka, T , Shimamoto, Y., and Fukushima, M Inhibition of oxonic acid on gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats Cancer Res., 53: 4004-4009, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 4004-4009
-
-
Shirasaka, T.1
Shimamoto, Y.2
Fukushima, M.3
-
8
-
-
0016809274
-
Chemotherapy of the human malignant melanoma transplanted in the nude mouse
-
Povlsen, C O., and Jacobsen, G. K. Chemotherapy of the human malignant melanoma transplanted in the nude mouse. Cancer Res., 35: 2790-2796, 1975.
-
(1975)
Cancer Res.
, vol.35
, pp. 2790-2796
-
-
Povlsen, C.O.1
Jacobsen, G.K.2
-
9
-
-
0017667524
-
Chemotherapy of human colon cancer xenografts in athymic nude mice
-
Phila.
-
Osieka, R , Houchens, D P , Goldin, A., and Johnson, R. K Chemotherapy of human colon cancer xenografts in athymic nude mice Cancer (Phila). 40: 2640-2650, 1977.
-
(1977)
Cancer
, vol.40
, pp. 2640-2650
-
-
Osieka, R.1
Houchens, D.P.2
Goldin, A.3
Johnson, R.K.4
-
10
-
-
0018099244
-
Experimental chemotherapy of carcinoma of the human stomach and colon serially transplanted in nude mice
-
Kubota, T., Shimosato, Y., and Nagai, K., Experimental chemotherapy of carcinoma of the human stomach and colon serially transplanted in nude mice Gann, 69: 299-309, 1978
-
(1978)
Gann
, vol.69
, pp. 299-309
-
-
Kubota, T.1
Shimosato, Y.2
Nagai, K.3
-
11
-
-
0022492520
-
Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice
-
Naito, S , von Eschenbach, A. C., Giavazzi, R., and Fidler, I J. Growth and metastasis of tumor cells isolated from a human renal cell carcinoma implanted into different organs of nude mice. Cancer Res., 46: 4109-4115, 1986.
-
(1986)
Cancer Res.
, vol.46
, pp. 4109-4115
-
-
Naito, S.1
Von Eschenbach, A.C.2
Giavazzi, R.3
Fidler, I.J.4
-
12
-
-
0023267736
-
A new animal model for human colon cancer metastasis
-
Bresalier, R. S., Raper, S. E., Hujanen, E S., and Kim, Y. S A new animal model for human colon cancer metastasis Int. J. Cancer, 39. 625-630, 1987.
-
(1987)
Int. J. Cancer
, vol.39
, pp. 625-630
-
-
Bresalier, R.S.1
Raper, S.E.2
Hujanen, E.S.3
Kim, Y.S.4
-
13
-
-
0025778637
-
Mucin production by human colonic carcinoma cells correlates with their metastatic potential in animal models of colon cancer metastasis
-
Bresalier, R. S , Niv, Y , Byrd, J. C., Duh, Q-Y , Toribara, N W , Rockwell, R. W., Dahiya, R., and Kim, Y. S. Mucin production by human colonic carcinoma cells correlates with their metastatic potential in animal models of colon cancer metastasis J Clin Invest , 87: 1037-1045, 1991.
-
(1991)
J Clin Invest
, vol.87
, pp. 1037-1045
-
-
Bresalier, R.S.1
Niv, Y.2
Byrd, J.C.3
Duh, Q.-Y.4
Toribara, N.W.5
Rockwell, R.W.6
Dahiya, R.7
Kim, Y.S.8
-
14
-
-
0025942251
-
Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens
-
Fu, X , Besterman, J M., Monosov, A., and Hoffman, R. M. Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens. Proc. Natl. Acad. Sci. USA, 88: 9345-9349, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 9345-9349
-
-
Fu, X.1
Besterman, J.M.2
Monosov, A.3
Hoffman, R.M.4
-
15
-
-
0027167893
-
A metastatic model of human colon cancer constructed using cecal implantation of cancer-tissue in nude mice
-
Furukawa, T., Kubota, T., Watanabe, M., Kuo, T-H., Nishibori, H., Saikawa, Y., Kase, S., Tanino, H , Teramoto, T., Ishibiki, K., and Kitajima, M. A metastatic model of human colon cancer constructed using cecal implantation of cancer-tissue in nude mice. Jpn. J. Surg., 23: 420-423, 1993.
-
(1993)
Jpn. J. Surg.
, vol.23
, pp. 420-423
-
-
Furukawa, T.1
Kubota, T.2
Watanabe, M.3
Kuo, T.-H.4
Nishibori, H.5
Saikawa, Y.6
Kase, S.7
Tanino, H.8
Teramoto, T.9
Ishibiki, K.10
Kitajima, M.11
-
16
-
-
0023893457
-
Comparison of intrapulmonary, percutaneous intrathoracic, and subcutaneous models for the propagation of human pulmonary and nonpulmonary cancer cell lines in athymic nude mice
-
McLemore, T. L., Eggleston, J. C., Shoemaker, R. H., Abbott, B J., Bohlman, M. E., Liu, M. C , Fine, D. L , Mayo, J G., and Boyd, M R Comparison of intrapulmonary, percutaneous intrathoracic, and subcutaneous models for the propagation of human pulmonary and nonpulmonary cancer cell lines in athymic nude mice. Cancer Res., 48. 2880-2886, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 2880-2886
-
-
McLemore, T.L.1
Eggleston, J.C.2
Shoemaker, R.H.3
Abbott, B.J.4
Bohlman, M.E.5
Liu, M.C.6
Fine, D.L.7
Mayo, J.G.8
Boyd, M.R.9
-
17
-
-
0023232571
-
Novel intrapulmonary model for orthotopic propagation of human lung cancers in athymic nude mice
-
McLemore, T. L., Liu, M C., Blacker, P. C., Gregg, M , Alley, M. C., Abbott, B J., Shoemaker, R. H., Bohlman, M. E., Litterst, C C., Hubbard, W. C., Brennan, R H., MacMahon, J. B., Fine, D. L., Eggleston, J. C., Mayo, J. G., and Boyd, M. R. Novel intrapulmonary model for orthotopic propagation of human lung cancers in athymic nude mice. Cancer Res., 47: 5132-5140, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 5132-5140
-
-
McLemore, T.L.1
Liu, M.C.2
Blacker, P.C.3
Gregg, M.4
Alley, M.C.5
Abbott, B.J.6
Shoemaker, R.H.7
Bohlman, M.E.8
Litterst, C.C.9
Hubbard, W.C.10
Brennan, R.H.11
MacMahon, J.B.12
Fine, D.L.13
Eggleston, J.C.14
Mayo, J.G.15
Boyd, M.R.16
-
18
-
-
0026747279
-
Orthotopic growth and metastasis of human prostate carcinoma in nude mice after transplantation of histologically-intact tissue
-
Fu, X., Herrera, H., and Hoffman, R. M. Orthotopic growth and metastasis of human prostate carcinoma in nude mice after transplantation of histologically-intact tissue. Int. J. Cancer., 52: 987-990, 1992
-
(1992)
Int. J. Cancer.
, vol.52
, pp. 987-990
-
-
Fu, X.1
Herrera, H.2
Hoffman, R.M.3
-
19
-
-
0027255332
-
A metastatic orthotopic-transplant-nude-mouse model of human patient breast cancer
-
Fu, X., Le, P. and Hoffman, R. M. A metastatic orthotopic-transplant-nude-mouse model of human patient breast cancer. Anticancer Res., 13: 901-904, 1993.
-
(1993)
Anticancer Res.
, vol.13
, pp. 901-904
-
-
Fu, X.1
Le, P.2
Hoffman, R.M.3
-
20
-
-
0027172156
-
A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice
-
Furukawa, T., Kubota, T., Watanabe, M., Kitajima, M., and Hoffman, R. M. A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice Cancer Res., 53: 3070-3072, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 3070-3072
-
-
Furukawa, T.1
Kubota, T.2
Watanabe, M.3
Kitajima, M.4
Hoffman, R.M.5
-
21
-
-
50549121134
-
The distribution of secondary growths in cancer of the breast
-
Paget, S. The distribution of secondary growths in cancer of the breast. Lancet, 1: 571-573, 1889.
-
(1889)
Lancet
, vol.1
, pp. 571-573
-
-
Paget, S.1
-
22
-
-
0025809857
-
A cooperative randomized study on tegafur plus mitomycin C versus combined tegafur and uracil plus mitomycin C in the treatment of advanced gastric cancer
-
Kurihara, M., Izumi, T., Yoshida, S., Ohkubo, T., Suga, S., Kiyohashi, A., Yaosaka, T., Takahashi, H., Ito, T., Sasai, T., Akiya, T , Akazawa, S., Betsuyaku, T , and Taguchi, S A cooperative randomized study on tegafur plus mitomycin C versus combined tegafur and uracil plus mitomycin C in the treatment of advanced gastric cancer. Jpn. J. Cancer Res., 82: 613-620, 1991.
-
(1991)
Jpn. J. Cancer Res.
, vol.82
, pp. 613-620
-
-
Kurihara, M.1
Izumi, T.2
Yoshida, S.3
Ohkubo, T.4
Suga, S.5
Kiyohashi, A.6
Yaosaka, T.7
Takahashi, H.8
Ito, T.9
Sasai, T.10
Akiya, T.11
Akazawa, S.12
Betsuyaku, T.13
Taguchi, S.14
-
23
-
-
0028099423
-
Phase II trial of uracil and tegafur plus oral leucovorin: An effective oral regimen in the treatment of metastatic colorectal carcinoma
-
Pazdur, R., Lassere, Y., Rhodes, V., Ajani, J. A , Sugarman, S. M., Patt, Y. Z., Jones, D. V., Jr., Marcowitz, A. B., Abbruzzese, J. L., and Bready, B. Phase II trial of uracil and tegafur plus oral leucovorin: an effective oral regimen in the treatment of metastatic colorectal carcinoma J. Clin Oncol , 12: 2296-2300, 1994.
-
(1994)
J. Clin Oncol
, vol.12
, pp. 2296-2300
-
-
Pazdur, R.1
Lassere, Y.2
Rhodes, V.3
Ajani, J.A.4
Sugarman, S.M.5
Patt, Y.Z.6
Jones Jr., D.V.7
Marcowitz, A.B.8
Abbruzzese, J.L.9
Bready, B.10
-
24
-
-
0029002283
-
A phase II trial of oral tegafur and uracil plus cisplatin in patients with inoperable nonsmall cell lung cancer
-
Phila.
-
Ichinose, Y., Takanashi, N., Yano, T., Asoh, H , Yokoyama, H., Tayama, K., Hara, N., and Ohta, M. A phase II trial of oral tegafur and uracil plus cisplatin in patients with inoperable nonsmall cell lung cancer. Cancer (Phila.), 75: 2677-2680, 1995.
-
(1995)
Cancer
, vol.75
, pp. 2677-2680
-
-
Ichinose, Y.1
Takanashi, N.2
Yano, T.3
Asoh, H.4
Yokoyama, H.5
Tayama, K.6
Hara, N.7
Ohta, M.8
-
25
-
-
0027399158
-
Prophylactic oral UFT therapy for superficial bladder cancer
-
Phila.
-
Kubota, Y , Hosaka, M , Fukushima, S., and Kondo, I Prophylactic oral UFT therapy for superficial bladder cancer. Cancer (Phila.), 71: 1842-1845, 1993.
-
(1993)
Cancer
, vol.71
, pp. 1842-1845
-
-
Kubota, Y.1
Hosaka, M.2
Fukushima, S.3
Kondo, I.4
-
26
-
-
0023917842
-
In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice
-
Morikawa, K., Walker, S. M., Jessup, J. M , and Fidler, I. J. In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice. Cancer Res., 48: 1943-1948, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 1943-1948
-
-
Morikawa, K.1
Walker, S.M.2
Jessup, J.M.3
Fidler, I.J.4
-
27
-
-
0024272364
-
Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice
-
Morikawa, K., Walker, S. M., Nakajima, M., Pathak, S , Jessup, J. M., and Fidler, I. J Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice. Cancer Res., 48: 6863-6871, 1988
-
(1988)
Cancer Res.
, vol.48
, pp. 6863-6871
-
-
Morikawa, K.1
Walker, S.M.2
Nakajima, M.3
Pathak, S.4
Jessup, J.M.5
Fidler, I.J.6
-
28
-
-
0019271884
-
High-pressure liquid chromatographic determination of Ftorafur[1-(tetrahydro-2-furany])-5-fluorouracil and GLC-mass spectrometric determination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus Ftorafur
-
Marunaka, T., Umeno, Y , Yoshida, K., Nagamachi, M., Minami, Y., and Fujii, S High-pressure liquid chromatographic determination of Ftorafur[1-(tetrahydro-2-furany])-5-fluorouracil] and GLC-mass spectrometric determination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus Ftorafur. J. Pharm. Sci., 69. 1296-1300, 1980
-
(1980)
J. Pharm. Sci.
, vol.69
, pp. 1296-1300
-
-
Marunaka, T.1
Umeno, Y.2
Yoshida, K.3
Nagamachi, M.4
Minami, Y.5
Fujii, S.6
-
29
-
-
0026725076
-
Significance of measuring 5-fluorouracil incorporated into RNA of tumor tissue as a parameter for the antitumor activity of 5-fluorouracil and its derivatives
-
in Japanese with English summary
-
Uchida, J., Umeno, Y., and Takeda, S. Significance of measuring 5-fluorouracil incorporated into RNA of tumor tissue as a parameter for the antitumor activity of 5-fluorouracil and its derivatives. Jpn. J. Cancer Chemother., 19: 677-683, 1992. (in Japanese with English summary)
-
(1992)
Jpn. J. Cancer Chemother.
, vol.19
, pp. 677-683
-
-
Uchida, J.1
Umeno, Y.2
Takeda, S.3
-
30
-
-
0141784878
-
Phosphorus compounds in animal tissues. III. A comparison of methods for the estimation of nucleic acids
-
Schneider, W. C. Phosphorus compounds in animal tissues. III. A comparison of methods for the estimation of nucleic acids. J. Biol. Chem , 227: 164-747, 1946.
-
(1946)
J. Biol. Chem
, vol.227
, pp. 164-747
-
-
Schneider, W.C.1
-
31
-
-
0020056302
-
In vivo kinetics of thymidylate synthetase inhibition in 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas
-
Spears, C. P., Shahinian, A. H., Moran, R. G., Heidelberger, C., and Corbert, T. In vivo kinetics of thymidylate synthetase inhibition in 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas. Cancer Res., 42: 450-456, 1982.
-
(1982)
Cancer Res.
, vol.42
, pp. 450-456
-
-
Spears, C.P.1
Shahinian, A.H.2
Moran, R.G.3
Heidelberger, C.4
Corbert, T.5
-
32
-
-
0027712907
-
The production of spontaneous lung metastasis model from transplanted colon carcinoma in nude rat. preliminary report
-
in Japanese
-
Morodomi, T., Isomoto, H., Akagi, Y., Araki, Y., Ogata, Y., Shirouzu, K , and Kakegawa, T. The production of spontaneous lung metastasis model from transplanted colon carcinoma in nude rat. preliminary report. Nippon Geka Gakkai Zasshi, 94: 1319, 1993. (in Japanese)
-
(1993)
Nippon Geka Gakkai Zasshi
, vol.94
, pp. 1319
-
-
Morodomi, T.1
Isomoto, H.2
Akagi, Y.3
Araki, Y.4
Ogata, Y.5
Shirouzu, K.6
Kakegawa, T.7
-
33
-
-
0024539308
-
A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: A mid-atlantic oncology program study
-
Lokich, J. J., Ahlgren, J. D., Gullo, J J , Philips, J. A., and Fryer, J. G. A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a mid-atlantic oncology program study J. Clin. Oncol. 7: 425-432, 1989.
-
(1989)
J. Clin. Oncol.
, vol.7
, pp. 425-432
-
-
Lokich, J.J.1
Ahlgren, J.D.2
Gullo, J.J.3
Philips, J.A.4
Fryer, J.G.5
-
34
-
-
0023735359
-
Continuous 5-fluorouracil infusion in advanced gastric carcinoma
-
Moyniham, T., Hansen, R., Anderson, T., Quebbeman, E., Beatty, P., Ausman, R , Ritch, P., Chitamber, C , and Vukelich, M. Continuous 5-fluorouracil infusion in advanced gastric carcinoma. Am. J. Clin. Oncol , 11, 461-464, 1988.
-
(1988)
Am. J. Clin. Oncol
, vol.11
, pp. 461-464
-
-
Moyniham, T.1
Hansen, R.2
Anderson, T.3
Quebbeman, E.4
Beatty, P.5
Ausman, R.6
Ritch, P.7
Chitamber, C.8
Vukelich, M.9
-
35
-
-
0024580507
-
Treatment of colorectal cancer and other malignancies with continuous infusion of 5-fluorouracil
-
Barbounis, V P , Kalofonos, H P., Munro, A J., McKenzie, C. G., Sackier, J M., and Epenetos, A. A. Treatment of colorectal cancer and other malignancies with continuous infusion of 5-fluorouracil. Anticancer Res., 9 33-40, 1989.
-
(1989)
Anticancer Res.
, vol.9
, pp. 33-40
-
-
Barbounis, V.P.1
Kalofonos, H.P.2
Munro, A.J.3
McKenzie, C.G.4
Sackier, J.M.5
Epenetos, A.A.6
-
36
-
-
0024532587
-
Low-dose continuous infusion 5-fluorouracil, evaluation in advanced breast carcinoma
-
Phila.
-
Huan, S., Pazdur, R., Singhakowinta, A., Samal, B., and Vaitkevicius, V. K. Low-dose continuous infusion 5-fluorouracil, evaluation in advanced breast carcinoma Cancer (Phila.), 63. 419-422, 1989.
-
(1989)
Cancer
, vol.63
, pp. 419-422
-
-
Huan, S.1
Pazdur, R.2
Singhakowinta, A.3
Samal, B.4
Vaitkevicius, V.K.5
-
37
-
-
0027323211
-
Phase I trial of 5-fluorouracil by 24-hour infusion weekly
-
Hass, N. B , Hines, J. B., Hudes, G R., Johnston, N., Ozols, R. F., and O'Dwyer, P. J. Phase I trial of 5-fluorouracil by 24-hour infusion weekly. Invest. New Drugs, 11 181-185, 1993.
-
(1993)
Invest. New Drugs
, vol.11
, pp. 181-185
-
-
Hass, N.B.1
Hines, J.B.2
Hudes, G.R.3
Johnston, N.4
Ozols, R.F.5
O'Dwyer, P.J.6
-
38
-
-
9344230555
-
Prolonged venous infusion of fluorouracil in colorectal cancer Pharmacological rationale, clinical experience and future directions
-
A Abad (ed.) Madrid: Graficas Monterreina
-
Anderson, N R , and Lokich, J J. Prolonged venous infusion of fluorouracil in colorectal cancer Pharmacological rationale, clinical experience and future directions. In: A Abad (ed.), Medical Treatment of Colorectal Cancer, pp. 144-173. Madrid: Graficas Monterreina, 1991
-
(1991)
Medical Treatment of Colorectal Cancer
, pp. 144-173
-
-
Anderson, N.R.1
Lokich, J.J.2
|