Somatic loss of p53 leads to stem/progenitor cell amplification in both mammary epithelial compartments, basal and luminal

Stem Cells

Volumn 31, Issue 9, 2013, Pages 1857-1867

  Chiche, Aurélie ^a,b   Moumen, Mejdi ^a,b   Petit, Valérie ^a,b   Jonkers, Jos ^c   Medina, Daniel ^d   Deugnier, Marie Ange ^a,b   Faraldo, Marisa M ^a,b   Glukhova, Marina A ^a,b  

^a INSTITUT CURIE   (France)

^b INSTITUT CURIE   (France)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Breast cancer; Mammary gland; p53; Progenitors; Self renewal; Stem cells

Indexed keywords

NOTCH RECEPTOR; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST EPITHELIUM; CELL COUNT; CELL CULTURE; CELL POPULATION; CELL PROLIFERATION; CELL REGENERATION; CELL RENEWAL; CELL STRUCTURE; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; GENE; GENE DELETION; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STEM CELL EXPANSION; TRP53 GENE;

BREAST CANCER; MAMMARY GLAND; P53; PROGENITORS; SELF-RENEWAL; STEM CELLS;

ANIMALS; CELL COMPARTMENTATION; CELL COUNT; CELL PROLIFERATION; CLONE CELLS; EPITHELIAL CELLS; FEMALE; GENE DELETION; HUMANS; INTEGRASES; KERATIN-5; MAMMARY GLANDS, ANIMAL; MICE; PROMOTER REGIONS, GENETIC; RECEPTORS, NOTCH; SPHEROIDS, CELLULAR; STEM CELLS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84885096739     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1429     Document Type: Article

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