메뉴 건너뛰기




Volumn 32, Issue 5, 2013, Pages 1171-1178

Purpurogallin exerts anti-inflammatory effects in lipopolysaccharide- stimulated BV2 microglial cells through the inactivation of the NF-KB and MAPK signaling pathways

Author keywords

Anti inflammation; Mitogen activated protein kinase; Nuclear factor KB; Phosphatidylinositol 3 kinase Akt; Purpurogallin

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHENOL DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E2; PURPUROGALLIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84885078824     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2013.1478     Document Type: Article
Times cited : (31)

References (50)
  • 2
    • 34547307366 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of neurodegenerative disorders
    • Reynolds A, Laurie C, Mosley RL and Gendelman HE: Oxidative stress and the pathogenesis of neurodegenerative disorders. Int Rev Neurobiol 82: 297-325, 2007.
    • (2007) Int Rev Neurobiol , vol.82 , pp. 297-325
    • Reynolds, A.1    Laurie, C.2    Mosley, R.L.3    Gendelman, H.E.4
  • 3
  • 4
    • 0037320253 scopus 로고    scopus 로고
    • Molecular insights on the cerebral innate immune system
    • Rivest S: Molecular insights on the cerebral innate immune system. Brain Behav Immun 17: 13-19, 2003.
    • (2003) Brain Behav Immun , vol.17 , pp. 13-19
    • Rivest, S.1
  • 5
    • 42449130907 scopus 로고    scopus 로고
    • Inflammation: A new candidate in modulating adult neurogenesis
    • Das S and Basu A: Inflammation: a new candidate in modulating adult neurogenesis. J Neurosci Res 86: 1199-1208, 2008.
    • (2008) J Neurosci Res , vol.86 , pp. 1199-1208
    • Das, S.1    Basu, A.2
  • 6
    • 79955582720 scopus 로고    scopus 로고
    • Multiple sclerosis as a neurodegenerative disease: Pathology, mechanisms and therapeutic implications
    • Stadelmann C: Multiple sclerosis as a neurodegenerative disease: pathology, mechanisms and therapeutic implications. Curr Opin Neurol 24 224-229, 2011.
    • (2011) Curr Opin Neurol , vol.24 , pp. 224-229
    • Stadelmann, C.1
  • 7
    • 77957028140 scopus 로고    scopus 로고
    • Microglial activation and chronic neurodegeneration
    • Lull ME and Block ML: Microglial activation and chronic neurodegeneration. Neurotherapeutics 7: 354-365, 2010.
    • (2010) Neurotherapeutics , vol.7 , pp. 354-365
    • Lull, M.E.1    Block, M.L.2
  • 8
    • 70350346842 scopus 로고    scopus 로고
    • The influence of microglia on the pathogenesis of parkinson's disease
    • Long-Smith C.M., Sullivan AM and Nolan YM: The influence of microglia on the pathogenesis of Parkinson's disease. Prog Neurobiol 89: 277-287, 2009
    • (2009) Prog Neurobiol , vol.89 , pp. 277-287
    • Long-Smith, C.M.1    Sullivan, A.M.2    Nolan, Y.M.3
  • 9
    • 0033214408 scopus 로고    scopus 로고
    • Flavonoids and isoflavonoids - A gold mine for metabolic engineering
    • Dixon RA and Steele CL Flavonoids and isoflavonoids - a gold mine for metabolic engineering. Trends Plant Sci 4 394-400, 1999.
    • (1999) Trends Plant Sci , vol.4 , pp. 394-400
    • Dixon, R.A.1    Steele, C.L.2
  • 11
    • 26444607492 scopus 로고    scopus 로고
    • Elimination of bitter, disgusting tastes of drugs And foods by cyclodextrins
    • Szejtli J and Szente L Elimination of bitter, disgusting tastes of drugs and foods by cyclodextrins. Eur J Pharm Biopharm 61: 115-125, 2005
    • (2005) Eur J Pharm Biopharm , vol.61 , pp. 115-125
    • Szejtli, J.1    Szente, L.2
  • 12
    • 34249780515 scopus 로고    scopus 로고
    • Structure-proteasome-inhibitory activity relationships of dietary flavonoids in human cancer cells
    • Chen D, Chen MS, Cui Q.C., Yang H and Dou QP: Structure-proteasome- inhibitory activity relationships of dietary flavonoids in human cancer cells. Front Biosci 12: 1935-1945, 2007
    • (2007) Front Biosci , vol.12 , pp. 1935-1945
    • Chen, D.1    Chen, M.S.2    Cui, Q.C.3    Yang, H.4    Dou, Q.P.5
  • 13
    • 0032986405 scopus 로고    scopus 로고
    • Inhibition of oncogene product enzyme activity as an approach to cancer chemoprevention. Tyrosine-specific protein kinase inhibition by purpurogallin from quercus sp nutgall
    • Abou-Karam M and Shier WT: Inhibition of oncogene product enzyme activity as an approach to cancer chemoprevention. Tyrosine-specific protein kinase inhibition by purpurogallin from Quercus sp nutgall. Phytother Res 13: 337-340, 1999
    • (1999) Phytother Res , vol.13 , pp. 337-340
    • Abou-Karam, M.1    Shier, W.T.2
  • 14
    • 0030580066 scopus 로고    scopus 로고
    • Molecular structure and antioxidant specificity of purpurogallin in three types of human cardiovascular cells
    • Wu TW, Zeng LH, Wu J, Fung K P, Weisel RD, Hempel A and Camerman N: Molecular structure and antioxidant specificity of purpurogallin in three types of human cardiovascular cells. Biochem Pharmacol 52: 1073-1080, 1996.
    • (1996) Biochem Pharmacol , vol.52 , pp. 1073-1080
    • Wu, T.W.1    Zeng, L.H.2    Wu, J.3    Fung, K.P.4    Weisel, R.D.5    Hempel, A.6    Camerman, N.7
  • 15
    • 0028124154 scopus 로고
    • Evaluation of hydroxyl radical-scav-enging property of purpurogallin using high pressure liquid chromatography
    • Prasad K and Laxdal VA: Evaluation of hydroxyl radical-scav-enging property of purpurogallin using high pressure liquid chromatography. Mol Cell Biochem 135: 153-158, 1994.
    • (1994) Mol Cell Biochem , vol.135 , pp. 153-158
    • Prasad, K.1    Laxdal, V.A.2
  • 16
    • 0027223398 scopus 로고
    • Purpurogallin as an anti-oxidant protector of human erythrocytes against lysis by peroxyl radicals
    • Sugiyama H, Fung KP and Wu TW: Purpurogallin as an anti-oxidant protector of human erythrocytes against lysis by peroxyl radicals. Life Sci 53: PL39-PL43, 1993.
    • (1993) Life Sci , vol.53
    • Sugiyama, H.1    Fung, K.P.2    Wu, T.W.3
  • 20
    • 0029874002 scopus 로고    scopus 로고
    • Purpurogallin inhibits DNA synthesis of murine fibrosarcoma L-929 and human U-87 MG glioblastoma cells in vitro
    • Fung KP, Wu TW and Lui CP: Purpurogallin inhibits DNA synthesis of murine fibrosarcoma L-929 and human U-87 MG glioblastoma cells in vitro. Chemotherapy 42: 199-205, 1996.
    • (1996) Chemotherapy , vol.42 , pp. 199-205
    • Fung, K.P.1    Wu, T.W.2    Lui, C.P.3
  • 21
    • 0141569444 scopus 로고    scopus 로고
    • Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/ Leukemia-2 proteins
    • Kitada S, Leone M, Sareth S., Zhai D, Reed JC and Pellecchia M: Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/ leukemia-2 proteins. J Med Chem 46: 4259-4264, 2003.
    • (2003) J Med Chem , vol.46 , pp. 4259-4264
    • Kitada, S.1    Leone, M.2    Sareth, S.3    Zhai, D.4    Reed, J.C.5    Pellecchia, M.6
  • 24
    • 33846609515 scopus 로고    scopus 로고
    • Peroxidase activity can dictate the in vitro lignin dehydrogenative polymer structure
    • Méchin V., Baumberger S, Pollet B and Lapierre C: Peroxidase activity can dictate the in vitro lignin dehydrogenative polymer structure. Phytochemistry 68: 571-579, 2007.
    • (2007) Phytochemistry , vol.68 , pp. 571-579
    • Méchin, V.1    Baumberger, S.2    Pollet, B.3    Lapierre, C.4
  • 25
    • 60849139418 scopus 로고    scopus 로고
    • Biocatalysis in water-in-ionic liquid microemulsions: A case study with horseradish peroxidase
    • Moniruzzaman M, Kamiya N and Goto M: Biocatalysis in water-in-ionic liquid microemulsions: a case study with horseradish peroxidase. Langmuir 25: 977-982, 2009.
    • (2009) Langmuir , vol.25 , pp. 977-982
    • Moniruzzaman, M.1    Kamiya, N.2    Goto, M.3
  • 26
    • 80054909414 scopus 로고    scopus 로고
    • Anti-inflammatory effects of polygala tenuifolia root through inhibition of NF-κB activation in lipo-polysaccharide-induced BV2 microglial cells
    • Cheong MH, Lee SR, Yoo H.S., Jeong J W, Kim GY, Kim W.J., Jung IC and Choi YH: Anti-inflammatory effects of Polygala tenuifolia root through inhibition of NF-κB activation in lipo-polysaccharide-induced BV2 microglial cells. J Ethnopharmacol 137: 1402-1408, 2011.
    • (2011) J Ethnopharmacol , vol.137 , pp. 1402-1408
    • Cheong, M.H.1    Lee, S.R.2    Yoo, H.S.3    Jeong, J.W.4    Kim, G.Y.5    Kim, W.J.6    Jung, I.C.7    Choi, Y.H.8
  • 27
    • 84861865524 scopus 로고    scopus 로고
    • Anti-inflammatory functions of purpurogallin in LPS-activated human endothelial cells
    • Kim TH, Ku SK, Lee IC and Bae JS: Anti-inflammatory functions of purpurogallin in LPS-activated human endothelial cells. BMB Rep 45: 200-205, 2012.
    • (2012) BMB Rep , vol.45 , pp. 200-205
    • Kim, T.H.1    Ku, S.K.2    Lee, I.C.3    Bae, J.S.4
  • 28
    • 84864094445 scopus 로고    scopus 로고
    • Synergy between adiponectin and interleukin-1β on the expression of interleukin-6, Interleukin-8, and cyclooxygenase-2 in fibroblast-like synoviocytes
    • Lee YA, Choi HM, Lee S.H., Yang HI, Yoo MC, Hong SJ and Kim KS: Synergy between adiponectin and interleukin-1β on the expression of interleukin-6, interleukin-8, and cyclooxygenase-2 in fibroblast-like synoviocytes. Exp Mol Med 44: 440-447, 2012.
    • (2012) Exp Mol Med , vol.44 , pp. 440-447
    • Lee, Y.A.1    Choi, H.M.2    Lee, S.H.3    Yang, H.I.4    Yoo, M.C.5    Hong, S.J.6    Kim, K.S.7
  • 30
    • 43549085501 scopus 로고    scopus 로고
    • NF-kappaB in inflammatory bowel disease
    • Atreya I, Atreya R and Neurath MF: NF-kappaB in inflammatory bowel disease. J Intern Med 263: 591-596, 2008.
    • (2008) J Intern Med , vol.263 , pp. 591-596
    • Atreya, I.1    Atreya, R.2    Neurath, M.F.3
  • 31
    • 0038266174 scopus 로고    scopus 로고
    • The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: Implications for therapy
    • Wright JG and Christman JW: The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: implications for therapy. Am J Respir Med 2: 211-219, 2003.
    • (2003) Am J Respir Med , vol.2 , pp. 211-219
    • Wright, J.G.1    Christman, J.W.2
  • 32
    • 33749123112 scopus 로고    scopus 로고
    • NF-kappaB and inflammation in genetic disease
    • Sebban H and Courtois G: NF-kappaB and inflammation in genetic disease. Biochem Pharmacol 72: 1153-1160, 2006.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1153-1160
    • Sebban, H.1    Courtois, G.2
  • 33
    • 0025302552 scopus 로고
    • Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter
    • Duyao MP, Buckler AJ and Sonenshein GE: Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter. Proc Natl Acad Sci USA 87: 4727-4731, 1990.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4727-4731
    • Duyao, M.P.1    Buckler, A.J.2    Sonenshein, G.E.3
  • 34
    • 34248572839 scopus 로고    scopus 로고
    • MAP kinases and the control of nuclear events
    • Turjanski AG, Vaqué JP and Gutkind JS: MAP kinases and the control of nuclear events. Oncogene 26: 3240-3253, 2007.
    • (2007) Oncogene , vol.26 , pp. 3240-3253
    • Turjanski, A.G.1    Vaqué, J.P.2    Gutkind, J.S.3
  • 35
    • 68949086867 scopus 로고    scopus 로고
    • Targeting the RAF-MEK-ERK pathway in cancer therapy
    • Montagut C and Settleman J: Targeting the RAF-MEK-ERK pathway in cancer therapy. Cancer Lett 283: 125-134, 2009.
    • (2009) Cancer Lett , vol.283 , pp. 125-134
    • Montagut, C.1    Settleman, J.2
  • 36
    • 33747463996 scopus 로고    scopus 로고
    • Microglia biology in health and disease
    • Garden GA and Möller T: Microglia biology in health and disease. J Neuroimmune Pharmacol 1: 127-137, 2006.
    • (2006) J Neuroimmune Pharmacol , vol.1 , pp. 127-137
    • Garden, G.A.1    Möller, T.2
  • 37
    • 60149097714 scopus 로고    scopus 로고
    • Differential microglial activation between acute stress and lipo-polysaccharide treatment
    • Sugama S, Takenouchi T, Fujita M., Conti B and Hashimoto M: Differential microglial activation between acute stress and lipo-polysaccharide treatment. J Neuroimmunol 207: 24-31, 2009.
    • (2009) J Neuroimmunol , vol.207 , pp. 24-31
    • Sugama, S.1    Takenouchi, T.2    Fujita, M.3    Conti, B.4    Hashimoto, M.5
  • 38
    • 77954865635 scopus 로고    scopus 로고
    • Systemic inflammatory cells fight off neurodegenerative disease
    • Schwartz M and Shechter R: Systemic inflammatory cells fight off neurodegenerative disease. Nat Rev Neurol 6: 405-410, 2010.
    • (2010) Nat Rev Neurol , vol.6 , pp. 405-410
    • Schwartz, M.1    Shechter, R.2
  • 39
    • 0035399785 scopus 로고    scopus 로고
    • Microglia in neurodegeneration: Molecular aspects
    • Gebicke-Haerter PJ: Microglia in neurodegeneration: molecular aspects. Micros Res Tech 54: 47-58, 2001.
    • (2001) Micros Res Tech , vol.54 , pp. 47-58
    • Gebicke-Haerter, P.J.1
  • 40
    • 28444486336 scopus 로고    scopus 로고
    • The function of microglia through purinergic receptors: Neuropathic pain and cytokine release
    • Inoue K: The function of microglia through purinergic receptors: neuropathic pain and cytokine release. Pharmacol Ther 109: 210-226, 2006.
    • (2006) Pharmacol Ther , vol.109 , pp. 210-226
    • Inoue, K.1
  • 41
    • 77956394596 scopus 로고    scopus 로고
    • Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS
    • Merson TD, Binder MD and Kilpatrick TJ: Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS. Neuromolecular Med 12: 99-132, 2 010.
    • (2010) Neuromolecular Med , vol.12 , pp. 99-132
    • Merson, T.D.1    Binder, M.D.2    Kilpatrick, T.J.3
  • 42
    • 0033961280 scopus 로고    scopus 로고
    • Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB
    • Madrid LV, Wang CY, Guttridge D.C., Schottelius AJ, Baldwin AS Jr and Mayo MW: Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB. Mol Cell Biol 20: 1626-1638, 2000.
    • (2000) Mol Cell Biol , vol.20 , pp. 1626-1638
    • Madrid, L.V.1    Wang, C.Y.2    Guttridge, D.C.3    Schottelius, A.J.4    Baldwin Jr., A.S.5    Mayo, M.W.6
  • 43
    • 32544439901 scopus 로고    scopus 로고
    • Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells
    • Lee JY, Jhun BS, Oh Y.T., Lee JH, Choe W, Baik HH, Ha J, Yoon K.S., Kim SS and Kang I: Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NF-kappaB activation in murine BV2 microglial cells. Neurosci Lett 396: 1-6, 2006.
    • (2006) Neurosci Lett , vol.396 , pp. 1-6
    • Lee, J.Y.1    Jhun, B.S.2    Oh, Y.T.3    Lee, J.H.4    Choe, W.5    Baik, H.H.6    Ha, J.7    Yoon, K.S.8    Kim, S.S.9    Kang, I.10
  • 44
    • 0036149025 scopus 로고    scopus 로고
    • The role of chemokines in human cardiovascular pathology: Enhanced biological insights
    • Shin WS, Szuba A and Rockson SG: The role of chemokines in human cardiovascular pathology: enhanced biological insights. Atherosclerosis 160: 91-102, 2002.
    • (2002) Atherosclerosis , vol.160 , pp. 91-102
    • Shin, W.S.1    Szuba, A.2    Rockson, S.G.3
  • 45
    • 33746862576 scopus 로고    scopus 로고
    • Naturally occurring NF-kappaB inhibitors
    • Nam NH: Naturally occurring NF-kappaB inhibitors. Mini Rev Med Chem 6: 945-951, 2006.
    • (2006) Mini Rev Med Chem , vol.6 , pp. 945-951
    • Nam, N.H.1
  • 46
    • 77954520406 scopus 로고    scopus 로고
    • NFkappaB: A promising target for natural products in cancer chemoprevention
    • Luqman S and Pezzuto JM: NFkappaB: a promising target for natural products in cancer chemoprevention. Phytother Res 24: 949-963, 2010.
    • (2010) Phytother Res , vol.24 , pp. 949-963
    • Luqman, S.1    Pezzuto, J.M.2
  • 47
    • 29144511607 scopus 로고    scopus 로고
    • MAPK signalling pathways as molecular targets for anti-inflammatory therapy - From molecular mechanisms to therapeutic benefits
    • Kaminska B: MAPK signalling pathways as molecular targets for anti-inflammatory therapy - from molecular mechanisms to therapeutic benefits. Biochim Biophys Acta 1754: 253-262, 2005.
    • (2005) Biochim Biophys Acta , vol.1754 , pp. 253-262
    • Kaminska, B.1
  • 48
    • 73849096467 scopus 로고    scopus 로고
    • MAPK signal transduction underlying brain inflammation and gliosis as therapeutic target
    • Kaminska B, Gozdz A, Zawadzka M., Ellert-Miklaszewska A and Lipko M: MAPK signal transduction underlying brain inflammation and gliosis as therapeutic target. Anat Rec (Hoboken) 292: 1902-1913, 2009.
    • (2009) Anat Rec (Hoboken) , vol.292 , pp. 1902-1913
    • Kaminska, B.1    Gozdz, A.2    Zawadzka, M.3    Ellert-Miklaszewska, A.4    Lipko, M.5
  • 49
    • 77954050569 scopus 로고    scopus 로고
    • Signaling pathways associated with inflam-matory bowel disease
    • Wei J and Feng J: Signaling pathways associated with inflam-matory bowel disease. Recent Pat Inflamm Allergy Drug Discov 4: 105-117, 2010.
    • (2010) Recent Pat Inflamm Allergy Drug Discov , vol.4 , pp. 105-117
    • Wei, J.1    Feng, J.2
  • 50
    • 0032579949 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia
    • Pyo H, Jou I, Jung S., Hong S and Joe EH: Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia. Neuroreport 9: 871-874, 1998.
    • (1998) Neuroreport , vol.9 , pp. 871-874
    • Pyo, H.1    Jou, I.2    Jung, S.3    Hong, S.4    Joe, E.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.