Short-term neonatal/prepubertal exposure of dibutyl phthalate (DBP) advanced pubertal timing and affected hypothalamic kisspeptin/GPR54 expression differently in female rats

Toxicology

Volumn 314, Issue 1, 2013, Pages 65-75

  Hu, Jialei ^a   Du, Guizhen ^a   Zhang, Wei ^a   Huang, Hongyu ^a   Chen, Danni ^a   Wu, Di ^a   Wang, Xinru ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Arcuate; DBP; Kisspeptin GPR54; Neonatal; Prepubertal; Puberty onset

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; G PROTEIN COUPLED RECEPTOR 54; KISSPEPTIN; LUTEINIZING HORMONE; PHTHALIC ACID DIBUTYL ESTER; G PROTEIN COUPLED RECEPTOR; KISS1R PROTEIN, RAT; SEX HORMONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; ESTRADIOL BLOOD LEVEL; ESTRUS CYCLE; FEMALE; HYPOTHALAMUS; IMMUNOREACTIVITY; LUTEINIZING HORMONE BLOOD LEVEL; NONHUMAN; PREPUBERTY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEXUAL MATURATION; ANAL CANAL; ANATOMY AND HISTOLOGY; ANIMAL; BIOSYNTHESIS; BLOOD; BODY WEIGHT; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENITAL SYSTEM; GROWTH, DEVELOPMENT AND AGING; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; NEWBORN; ORGAN SIZE; OVARY; PATHOLOGY; PHYSIOLOGY; PREGNANCY; RADIOIMMUNOASSAY; REAL TIME POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TOXICITY; VAGINA;

RATTUS;

ANAL CANAL; ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; DIBUTYL PHTHALATE; ESTROUS CYCLE; FEMALE; GENE EXPRESSION REGULATION; GENITALIA; GONADAL STEROID HORMONES; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; ORGAN SIZE; OVARY; PREGNANCY; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; SEXUAL MATURATION; VAGINA;

EID: 84885067073     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2013.09.007     Document Type: Article

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