An opposite-direction modulation of the COMT val158met polymorphism on the clinical response to intrathecal morphine and triptans

Journal of Pain

Volumn 14, Issue 10, 2013, Pages 1097-1106

  Cargnin, Sarah ^a   Magnani, Francesco ^b   Viana, Michele ^c   Tassorelli, Cristina ^c   Mittino, Daniela ^d   Cantello, Roberto ^d   Sances, Grazia ^c   Nappi, Giuseppe ^c   Canonico, Pier Luigi ^a   Genazzani, Armando A ^a   Raffaeli, William ^b   Terrazzino, Salvatore ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b Institute for Research on Pain   (Italy)

^c C MONDINO NATIONAL NEUROLOGICAL INSTITUTE   (Italy)

^d MAGGIORE DELLA CARITÀ HOSPITAL   (Italy)

Author keywords

COMT polymorphism; Low back pain; migraine; morphine; response; triptans

Indexed keywords

ALMOTRIPTAN; CATECHOL METHYLTRANSFERASE; ELETRIPTAN; FROVATRIPTAN; MORPHINE; RIZATRIPTAN; SUMATRIPTAN; TRIPTAN DERIVATIVE; ZOLMITRIPTAN;

ADULT; ALLELE; ARTICLE; FEMALE; HOMOZYGOSITY; HUMAN; LOW BACK PAIN; MAJOR CLINICAL STUDY; MALE; MIGRAINE; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT RESPONSE;

COMT POLYMORPHISM; LOW BACK PAIN; MIGRAINE; MORPHINE; RESPONSE; TRIPTANS;

ADULT; AGED; ANALGESICS, OPIOID; CARBAZOLES; CATECHOL O-METHYLTRANSFERASE; COHORT STUDIES; FEMALE; GENOTYPE; HUMANS; INJECTIONS, SPINAL; LOW BACK PAIN; MALE; MIDDLE AGED; MIGRAINE DISORDERS; MORPHINE; MULTIVARIATE ANALYSIS; PAIN; PAIN MEASUREMENT; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PREDICTIVE VALUE OF TESTS; TREATMENT OUTCOME; TRYPTAMINES;

EID: 84885020814     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2013.04.006     Document Type: Article

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