Does sumatriptan cross the blood-brain barrier in animals and man?

Journal of Headache and Pain

Volumn 11, Issue 1, 2010, Pages 5-12

  Tfelt Hansen, Peer Carsten ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Animal studies; Blood brain barrier; CNS; Human studies; Migraine; Sumatriptan

Indexed keywords

ALMOTRIPTAN; CARBON 14; ELETRIPTAN; GLYCOPROTEIN P; MANNITOL; MORPHINE; NARATRIPTAN; PLACEBO; PROTEIN C FOS; RIZATRIPTAN; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 1D RECEPTOR; SUMATRIPTAN; TEMAZEPAM; ZOLMITRIPTAN;

AKATHISIA; ALPHA RHYTHM; ANTINOCICEPTION; AUTOPSY; BETA RHYTHM; BINDING SITE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN REGION; CLINICAL TRIAL; DELTA RHYTHM; DIZZINESS; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG MEGADOSE; DRUG PENETRATION; DYSTONIA; EUPHORIA; EXERCISE; FATIGUE; GLOBUS PALLIDUS; HIPPOCAMPUS; HUMAN; HYDROPHILICITY; IMMUNOREACTIVITY; MIGRAINE; NEUROLOGIC DISEASE; NONHUMAN; OBSESSIVE COMPULSIVE DISORDER; PATHOLOGICAL LAUGHTER; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVIEW; SEDATION; SIDE EFFECT; SOMNOLENCE; THETA RHYTHM; THINKING IMPAIRMENT; TRIGEMINAL NUCLEUS; VOLUNTEER;

ANIMALS; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MIGRAINE DISORDERS; SEROTONIN AGONISTS; SUMATRIPTAN;

EID: 77149139821     PISSN: 11292369     EISSN: 11292377     Source Type: Journal    
DOI: 10.1007/s10194-009-0170-y     Document Type: Review

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