Novel mixed-ligand copper(I) complexes: Role of diimine ligands on cytotoxicity and genotoxicity

Journal of Medicinal Chemistry

Volumn 56, Issue 18, 2013, Pages 7416-7430

  Gandin, Valentina ^a   Porchia, Marina ^b   Tisato, Francesco ^b   Zanella, Alessandro ^b   Severin, Emilia ^c   Dolmella, Alessandro ^a   Marzano, Cristina ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b CNR   (Italy)

^c CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; COPPER COMPLEX; DIIMINE; IMINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; COMET ASSAY; CONTROLLED STUDY; DNA DETERMINATION; DNA FRAGMENTATION; DRUG CYTOTOXICITY; ELECTROSPRAY MASS SPECTROMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MICRONUCLEUS TEST; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PERIPHERAL LYMPHOCYTE; X RAY DIFFRACTION;

ANEUGENS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CELL CYCLE; CELL LINE, TUMOR; COPPER; DNA; DNA FRAGMENTATION; HUMANS; IMINES; LIGANDS; MICRONUCLEUS TESTS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; ORGANOMETALLIC COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84885013620     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm400965m     Document Type: Article

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