Effect of olmesartan on leukocyte recruitment in choroid-sclera complex in hypercholesterolemia model

Journal of Ocular Pharmacology and Therapeutics

Volumn 29, Issue 8, 2013, Pages 709-714

  Torres, Rogil Jose De Almeida ^a   De Noronha, Lucia ^a   Casella, Antonio Marcelo Barbante ^b   Grobe, Sarah Fagundes ^a   Martins, Isabela De Carvalho ^a   Torres, Regiane Do Rocio De Almeida ^a   Luchini, Andrea ^c   Sturzeneker, Mario Claudio Soares ^d   Torres, Caroline Luzia De Almeida ^e   Precoma, Dalton Bertolim ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF PARANÁ   (Brazil)

^b STATE UNIVERSITY OF LONDRINA   (Brazil)

^c Centro Oftalmologico de Curitiba   (Brazil)

^d Santa Casa de Misericordia Hospital   (Brazil)

^e POSITIVO UNIVERSITY   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; MONOCYTE CHEMOTACTIC PROTEIN 1; OLMESARTAN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CHOLESTEROL BLOOD LEVEL; CHOROID; CONTROLLED STUDY; DIET RESTRICTION; GLUCOSE BLOOD LEVEL; HYPERCHOLESTEROLEMIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MACROPHAGE; MALE; MORPHOMETRICS; NONHUMAN; PROTEIN EXPRESSION; RABBIT; SCLERA; TRIACYLGLYCEROL BLOOD LEVEL;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; CHEMOKINE CCL2; CHEMOTAXIS, LEUKOCYTE; CHOROID; DISEASE MODELS, ANIMAL; HYPERCHOLESTEROLEMIA; IMIDAZOLES; LIPIDS; MACROPHAGES; MACULAR DEGENERATION; MALE; RABBITS; SCLERA; TETRAZOLES;

EID: 84885009518     PISSN: 10807683     EISSN: 15577732     Source Type: Journal    
DOI: 10.1089/jop.2012.0142     Document Type: Article

References (37)

1. Friedman, D.S., et al. Prevalence of age-related macular degeneration in the United States. Arch. Ophthalmol. 122:564-572, 2004
2. Friedman, E. A hemodynamic model of the pathogenesis of age-related macular degeneration. Am. J. Ophthalmol. 124: 677-682, 1997
3. Friedman, E. The role of the atherosclerotic process in the pathogenesis of age-related macular degeneration. Am. J. Ophthalmol. 130:658-663, 2000
4. Oh, H., et al. The potential angiogenic role of macrophages in the formation of choroidal neovascular membranes. Invest. Ophthalmol. Vis. Sci. 40:1891-1898, 1999
5. Steen, B., Sejersen, S., Berglin, L., Seregard, S., and Kvanta, A. Matrix metalloproteinases and metalloproteinases inhibitors in choroidal neovascular membranes. Invest. Ophthalmol. Vis. Sci. 39:2194-2200, 1998
6. Grossniklaus, H.E., et al. Macrophage and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization. Mol. Vis. 8:119-126, 2002
7. Sakurai, E., et al. Targeted disruption of the CD18 or ICAM-1 gene inhibits choroidal neovascularization. Invest. Ophthalmol. Vis. Sci. 44:2743-2749, 2003
8. Salazar, J.J., et al. Alterations in the choroid in hypercholesterolemic rabbits: reversibility after normalization of cholesterol levels. Exp. Eye Res. 84:412-422, 2007
9. Torres, R.J.A., et al. Avaliacao das alteracoes precoces na coro ide e esclera ocorridas em coelhos hipercolesterole micos. Estudo histolo gico e histomorfometrico. Arq. Bras. Oftalmol. 72:68-74, 2009
10. Libby, P. Inflammation in atherosclerosis. Nature. 420:868-874, 2002
11. Cousins, S.W., Espinosa-Heidmann, D.G., and Csaky, K.G. Monocyte activation in patients with age-related macular degeneration. Arch. Ophthalmol. 122:1013-1018, 2004
12. Sakurai, E., Anand, A., Ambati, B.K., van Rooijen, N., and Ambati, J. Macrophage depletion inhibits experimental choroidal neovascularization. Invest. Ophthalmol. Vis. Sci. 44:3578-3585, 2003
13. Nagai, N., et al. Angiotensin II type 1 receptor-mediated inflammation is required for choroidal neovascularization. Arterioscler. Thromb. Vasc. Biol. 26:2252-2259, 2006
14. Satofuka, S., et al. (Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system. Am. J. Pathol. 173:1911-1918, 2008
15. Sun, Y.P., Lu, N.C., Parmley, Y.W.W., and Hollenbeck, C.B. Effects of cholesterol diets on vascular function and atherogenesis in rabbits. Proc. Soc. Exp. Biol. Med. 224:166-171, 2000
16. Torres, R.J., et al. Evaluation of early abnormalities of the sensory retina in a hypercholesterolemia experimental model: an immunohistochemical study. Arq. Bras. Oftalmol. 72:793-798, 2009
17. Torres, R.J., et al. Sclerochorioretinal abnormalities in hypercholesterolemic rabbits treated with rosiglitazone. Ophthalmic Surg. Lasers Imaging. 41:562-571, 2010
18. Ross, R. Atherosclerosis: an inflammatory disease. N. Engl. J. Med. 340:115-126, 1999
19. Nicolletti, A., Caligiuri, G., and Hansson, G.K. Immunomodulation of atherosclerosis: myth and reality. J. Intern. Med. 247:397-405, 2000
20. Sallusto, F., Mackay, C.R., and Lanzavecchia, A. The role of chemokine receptors in primary, effector, and memory immune responses. Annu. Rev. Immunol. 18:593-620, 2000
21. Charo, I.F., and Taubman, M.B. Chemokines in the pathogenesis of vascular disease. Circ. Res. 95:858-866, 2004
22. Weber, C., Schober, A., and Zernecke, A. Chemokines: key regulators of mononuclear cell recruitment in atherosclerotic vascular disease. Arterioscler. Thromb. Vasc. Biol. 24:1997-2008, 2004
23. Nelken, N.A., Coughlin, S.R., Gordon, D., and Wilcox, J.N. Monocyte chemoattractant protein-1 in human atheromatous plaques. J. Clin. Invest. 88:1121-1127, 1991
24. Yla-Herttuala, S., et al. Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc. Natl. Acad. Sci. U. S. A. 88:5252-5256, 1991
25. Holtkamp, G.M., De Vos, A.F., Peek, R., and Kijlsta, A. Analysis of the secretion pattern of monocyte chemotactic protein-1 (MCP-1) and transforming growth factor-beta 2 (TGF-beta2) by human retinal pigment epithelial cells. Clin. Exp. Immunol. 118:35-40, 1999
26. Torres, R.J.A., et al. Fatores modificaveis da macular relacionada aidade Arq. Bras. Oftalmol. 72:406-412, 2009
27. Ruberti, J.W., Curcio, C.A., Millican, C.L., Menco, B.P., Huang, J.D., and Johnson, M. Quick-freeze/deep-etch visualization of age-related lipid accumulation in Bruch's membrane. Invest. Ophthalmol. Vis. Sci. 44:1753-1759, 2003
28. Mata, N.L., Weng, J., and Travis, G.H. Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration. Proc. Natl. Acad. Sci. U. S. A. 9:7154-7159, 2000
29. Higgins, G.T., Wang, J.H., Dockery, P., Cleary, P.E., and Redmond, H.P. Induction of angiogenic cytokine expression in cultured RPE by ingestion of oxidized photoreceptor outer segments. Invest. Ophthalmol. Vis. Sci. 44:1775-1782, 2003
30. Mizuno, M., et al. Pharmacology of CS-866, a novel nonpeptide angiotensin II receptor antagonist. Eur. J. Pharmacol. 285:181-188, 1995
31. Van der Hoorn, J.W., et al. Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3-Leiden transgenic mice. J. Hypertens. 25:25-62, 2007
32. Dol, F., et al. Angiotensin AT1 receptor antagonist irbesartan decreases lesion size, chemokine expression, and macrophage accumulation in apolipoprotein E-deficient mice. J. Cardiovasc. Pharmacol. 38:395-305, 2001
33. Sola, S., et al. Irbesartan and lipoic acid improve endothelial function and reduce markers of inflammation in the metabolic syndrome: results of the irbesartan and lipoic acid in endothelial dysfunction (ISLAND) study. Circulation. 111: 343-348, 2005
34. Ferder, L., Inserra, F., and Martinez-Maldonado, M. Inflammation and the metabolic syndrome: role of angiotensin II and oxidative stress. Curr. Hypertens. Rep. 8:191-198, 2006
35. Brasier, A.R., Recinos, A., and Eledrisi, M.S. Vascular inflammation and the renin-angiotensin system. Arterioscler. Thromb. Vasc. Biol. 22:1257-1266, 2002
36. Hikichi, T., et al. Inhibitory effect of losartan on laser-induced choroidal neovascularization in rats. Am. J. Ophthalmol. 132:587-589, 2001
37. Ambati, J., et al. An animal model of age-related macular degeneration in senescent Ccl-2-or Ccr-2-deficient mice. Nat. Med. 9:1390-1397, 2003.