MicroRNA-182 promotes tumor cell growth by targeting transcription elongation factor a-like 7 in endometrial carcinoma

Cellular Physiology and Biochemistry

Volumn 32, Issue 3, 2013, Pages 581-590

  Guo, Ying ^a   Liao, Ying ^a   Jia, Chunyan ^a   Ren, Jianlin ^a   Wang, Jianchao ^a   Li, Ting ^a  

^a Shanghai Traditional Chinese Medicine (TCM) Integrated Hospital   (China)

Author keywords

Endometrial carcinoma; miR 182; TCEAL7

Indexed keywords

CYCLIN D1; LENTIVIRUS VECTOR; MESSENGER RNA; MICRORNA 182; MYC PROTEIN; TRANSCRIPTION ELONGATION FACTOR A LIKE 7; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; ELONGATION FACTOR A LIKE 7; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

3' UNTRANSLATED REGION; ARTICLE; CARCINOMA CELL; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; ENDOMETRIUM; ENDOMETRIUM CARCINOMA; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA BINDING; TUMOR GROWTH; UPREGULATION; WESTERN BLOTTING; CANCER GROWTH; FEMALE; REAL TIME POLYMERASE CHAIN REACTION;

3' UNTRANSLATED REGIONS; CELL LINE; CELL PROLIFERATION; CYCLIN D1; DOWN-REGULATION; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; MICRORNAS; NF-KAPPA B; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; RNA, MESSENGER; UP-REGULATION;

EID: 84884993386     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000354462     Document Type: Article

References (36)

1. Jemal A, Siegel R, Xu J, Ward E: Cancer statistics, 2010. CA Cancer J Clin 2010;60: 277-300.
2. Dizon DS: Treatment options for advanced endometrial carcinoma. Gynecol Oncol 2010;117: 373-381.
3. Dong P, Kaneuchi M, Konno Y, Watari H, Sudo S, Sakuragi N: Emerging therapeutic biomarkers in endometrial cancer. Biomed Res Int 2013;2013: 130362.
4. Skaftnesmo KO, Prestegarden L, Micklem DR, Lorens JB: Micrornas in tumorigenesis. Curr Pharm Biotechnol 2007;8: 320-325.
5. Temkin SM, Fleming G: Current treatment of metastatic endometrial cancer. Cancer Control 2009;16: 38-45.
6. Valencia-Sanchez MA, Liu J, Hannon GJ, Parker R: Control of translation and mrna degradation by mirnas and sirnas. Genes Dev 2006;20: 515-524.
7. Rana TM: Illuminating the silence: Understanding the structure and function of small rnas. Nat Rev Mol Cell Biol 2007;8: 23-36.
8. Esquela-Kerscher A, Slack FJ: Oncomirs - micrornas with a role in cancer. Nat Rev Cancer 2006;6: 259-269.
9. Wang D, Qiu C, Zhang H, Wang J, Cui Q, Yin Y: Human microrna oncogenes and tumor suppressors show significantly different biological patterns: From functions to targets. PLoS One 2010;5.
10. Lee H, Choi HJ, Kang CS, Lee HJ, Lee WS, Park CS: Expression of mirnas and pten in endometrial specimens ranging from histologically normal to hyperplasia and endometrial adenocarcinoma. Mod Pathol 2012;25: 1508-1515.
11. Ratner ES, Tuck D, Richter C, Nallur S, Patel RM, Schultz V, Hui P, Schwartz PE, Rutherford TJ, Weidhaas JB: Microrna signatures differentiate uterine cancer tumor subtypes. Gynecol Oncol 2010;118: 251-257.
12. Wu W, Lin Z, Zhuang Z, Liang X: Expression profile of mammalian micrornas in endometrioid adenocarcinoma. Eur J Cancer Prev 2009;18: 50-55.
13. Chung TK, Cheung TH, Huen NY, Wong KW, Lo KW, Yim SF, Siu NS, Wong YM, Tsang PT, Pang MW, Yu MY, To KF, Mok SC, Wang VW, Li C, Cheung AY, Doran G, Birrer MJ, Smith DI, Wong YF: Dysregulated micrornas and their predicted targets associated with endometrioid endometrial adenocarcinoma in hong kong women. Int J Cancer 2009;124: 1358-1365.
14. Chien J, Staub J, Avula R, Zhang H, Liu W, Hartmann LC, Kaufmann SH, Smith DI, Shridhar V: Epigenetic silencing of tceal7 (bex4) in ovarian cancer. Oncogene 2005;24: 5089-5100.
15. Huang CY, Chen YM, Zhao JJ, Chen YB, Jiang SS, Yan SM, Zhao BW, Pan K, Wang DD, Lv L, Li YF, Wang W, Zhou ZW, Xia JC: Decreased expression of transcription elongation factor a-like 7 is associated with gastric adenocarcinoma prognosis. PLoS One 2013;8:e54671.
16. Chien J, Narita K, Rattan R, Giri S, Shridhar R, Staub J, Beleford D, Lai J, Roberts LR, Molina J, Kaufmann SH, Prendergast GC, Shridhar V: A role for candidate tumor-suppressor gene tceal7 in the regulation of c-myc activity, cyclin d1 levels and cellular transformation. Oncogene 2008;27: 7223-7234.
17. Lafferty-Whyte K, Bilsland A, Hoare SF, Burns S, Zaffaroni N, Cairney CJ, Keith WN: Tceal7 inhibition of c-myc activity in alternative lengthening of telomeres regulates htert expression. Neoplasia 2010;12: 405-414.
18. Rattan R, Narita K, Chien J, Maguire JL, Shridhar R, Giri S, Shridhar V: Tceal7, a putative tumor suppressor gene, negatively regulates nf-kappab pathway. Oncogene 2010;29: 1362-1373.
19. Mercader A, Valbuena D, Simon C: Human embryo culture. Methods Enzymol 2006;420: 3-18.
20. Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t)) method. Methods 2001;25: 402-408.
21. Boren T, Xiong Y, Hakam A, Wenham R, Apte S, Wei Z, Kamath S, Chen DT, Dressman H, Lancaster JM: Micrornas and their target messenger rnas associated with endometrial carcinogenesis. Gynecol Oncol 2008;110: 206-215.
22. Zhang L, Volinia S, Bonome T, Calin GA, Greshock J, Yang N, Liu CG, Giannakakis A, Alexiou P, Hasegawa K, Johnstone CN, Megraw MS, Adams S, Lassus H, Huang J, Kaur S, Liang S, Sethupathy P, Leminen A, Simossis VA, Sandaltzopoulos R, Naomoto Y, Katsaros D, Gimotty PA, DeMichele A, Huang Q, Butzow R, Rustgi AK, Weber BL, Birrer MJ, Hatzigeorgiou AG, Croce CM, Coukos G: Genomic and epigenetic alterations deregulate microrna expression in human epithelial ovarian cancer. Proc Natl Acad Sci U S A 2008;105: 7004-7009.
23. Wyman SK, Parkin RK, Mitchell PS, Fritz BR, O'Briant K, Godwin AK, Urban N, Drescher CW, Knudsen BS, Tewari M: Repertoire of micrornas in epithelial ovarian cancer as determined by next generation sequencing of small rna cdna libraries. PLoS One 2009;4:e5311.
24. Martinez I, Gardiner AS, Board KF, Monzon FA, Edwards RP, Khan SA: Human papillomavirus type 16 reduces the expression of microrna-218 in cervical carcinoma cells. Oncogene 2008;27: 2575-2582.
25. Tang T, Wong HK, Gu W, Yu MY, To KF, Wang CC, Wong YF, Cheung TH, Chung TK, Choy KW: Microrna-182 plays an onco-mirna role in cervical cancer. Gynecol Oncol 2013;129: 199-208.
26. Gupta A, Caffrey E, Callagy G, Gupta S: Oestrogen-dependent regulation of mirna biogenesis: Many ways to skin the cat. Biochem Soc Trans 2012;40: 752-758.
27. Yan D, Dong XD, Chen X, Yao S, Wang L, Wang J, Wang C, Hu DN, Qu J, Tu L: Role of microrna-182 in posterior uveal melanoma: Regulation of tumor development through mitf, bcl2 and cyclin d2. PLoS One 2012;7:e40967.
28. Sun Y, Fang R, Li C, Li L, Li F, Ye X, Chen H: Hsa-mir-182 suppresses lung tumorigenesis through down regulation of rgs17 expression in vitro. Biochem Biophys Res Commun 2010;396: 501-507.
29. Kong WQ, Bai R, Liu T, Cai CL, Liu M, Li X, Tang H: Microrna-182 targets camp-responsive element-binding protein 1 and suppresses cell growth in human gastric adenocarcinoma. FEBS J 2012;279: 1252-1260.
30. Guttilla IK, White BA: Coordinate regulation of foxo1 by mir-27a, mir-96, and mir-182 in breast cancer cells. J Biol Chem 2009;284: 23204-23216.
31. Segura MF, Hanniford D, Menendez S, Reavie L, Zou X, Alvarez-Diaz S, Zakrzewski J, Blochin E, Rose A, Bogunovic D, Polsky D, Wei J, Lee P, Belitskaya-Levy I, Bhardwaj N, Osman I, Hernando E: Aberrant mir-182 expression promotes melanoma metastasis by repressing foxo3 and microphthalmia-associated transcription factor. Proc Natl Acad Sci U S A 2009;106: 1814-1819.
32. Wang YQ, Guo RD, Guo RM, Sheng W, Yin LR: Microrna-182 promotes cell growth, invasion, and chemoresistance by targeting programmed cell death 4 (pdcd4) in human ovarian carcinomas. J Cell Biochem 2013;114: 1464-1473.
33. Liu H, Du L, Wen Z, Yang Y, Li J, Wang L, Zhang X, Liu Y, Dong Z, Li W, Zheng G, Wang C: Up-regulation of mir-182 expression in colorectal cancer tissues and its prognostic value. Int J Colorectal Dis 2013;28: 697-703.
34. Wang J, Li J, Shen J, Wang C, Yang L, Zhang X: Microrna-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma. BMC Cancer 2012;12: 227.
35. Liu Z, Liu J, Segura MF, Shao C, Lee P, Gong Y, Hernando E, Wei JJ: Mir-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma. J Pathol 2012;228: 204-215.
36. Schaefer A, Jung M, Mollenkopf HJ, Wagner I, Stephan C, Jentzmik F, Miller K, Lein M, Kristiansen G, Jung K: Diagnostic and prognostic implications of microrna profiling in prostate carcinoma. Int J Cancer 2010;126: 1166-1176.