Acute chest syndrome is associated with single nucleotide polymorphism-defined beta globin cluster haplotype in children with sickle cell anaemia

British Journal of Haematology

Volumn 163, Issue 2, 2013, Pages 268-276

  Bean, Christopher J ^a   Boulet, Sheree L ^b   Yang, Genyan ^a   Payne, Amanda B ^a   Ghaji, Nafisa ^a   Pyle, Meredith E ^a   Hooper, W Craig ^a   Bhatnagar, Pallav ^c   Keefer, Jeffrey ^c   Barron Casella, Emily A ^c   Casella, James F ^c   Debaun, Michael R ^d  

^a NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

^b NATIONAL CENTER FOR CHRONIC DISEASE PREVENTION AND HEALTH PROMOTION   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

globin; Acute chest syndrome; Genetic analysis; Haplotype; Sickle cell anaemia

Indexed keywords

DNA; HEME OXYGENASE 1; HEMOGLOBIN ALPHA CHAIN; HEMOGLOBIN BETA CHAIN; HEMOGLOBIN F; HEMOGLOBIN S;

ACUTE CHEST SYNDROME; ALLELE; ARTICLE; BRAIN INFARCTION; CHILD; CLINICAL TRIAL (TOPIC); DISEASE ASSOCIATION; FEMALE; GENE; GENE CLUSTER; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; HAPLOTYPE; HBA1 GENE; HBA2 GENE; HBB GENE; HBSS GENE; HETEROZYGOTE; HMOX1 GENE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SICKLE CELL ANEMIA; SINGLE NUCLEOTIDE POLYMORPHISM;

Β-GLOBIN; ACUTE CHEST SYNDROME; GENETIC ANALYSIS; HAPLOTYPE; SICKLE CELL ANAEMIA;

ACUTE CHEST SYNDROME; ADOLESCENT; ALLELES; ANEMIA, SICKLE CELL; BETA-GLOBINS; CHILD; CHILD, PRESCHOOL; FEMALE; FETAL HEMOGLOBIN; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MULTIGENE FAMILY; PATIENT ADMISSION; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84884974179     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.12507     Document Type: Article

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