Annotation and characterization of the Plasmodium vivax rhoptry neck protein 4 (PvRON4)

Malaria Journal

Volumn 12, Issue 1, 2013, Pages

  Arévalo Pinzón, Gabriela ^a,b   Curtidor, Hernando ^a,b   Abril, Jesica ^a   Patarroyo, Manuel A ^a,b  

^a FUNDACIÓN INSTITUTO DE INMUNOLOGÍA DE COLOMBIA FIDIC   (Colombia)

^b UNIVERSIDAD DEL ROSARIO   (Colombia)

Author keywords

Bioinformatics analysis; Invasion; Plasmodium vivax; Rhoptry; Rhoptry neck protein; Tight junction

Indexed keywords

PLASMODIUM VIVAX RHOPTRY NECK PROTEIN 4; PROTEIN; PROTOZOAL PROTEIN; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; ANTIBODY AFFINITY; ANTIGENICITY; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; EXON; GENE STRUCTURE; GENETIC TRANSCRIPTION; GENOME ANALYSIS; HYDROPHILICITY; IMMUNOFLUORESCENCE; IMMUNOGENICITY; INTRON; MACACA FASCICULARIS; MEROZOITE; MOLECULAR GENETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PLASMODIUM KNOWLESI; PLASMODIUM VIVAX; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHIZONT; SEQUENCE ANALYSIS; SPOROZOITE; START CODON; SYNTENY; TANDEM REPEAT; TARGET CELL;

CLUSTER ANALYSIS; DNA, PROTOZOAN; GENE EXPRESSION PROFILING; MOLECULAR SEQUENCE DATA; PHYLOGEOGRAPHY; PLASMODIUM VIVAX; PROTEIN TRANSPORT; PROTOZOAN PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY; SYNTENY;

EID: 84884962736     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-12-356     Document Type: Article

References (51)

1. WHO, World malaria report Geneva: WHO Press 2011
2. Vivax malaria: neglected and not benign. Price RN, Tjitra E, Guerra CA, Yeung S, White NJ, Anstey NM, Am J Trop Med Hyg 2007 77 79 87 18165478
3. Cerebral involvement in benign tertian malaria. Beg MA, Khan R, Baig SM, Gulzar Z, Hussain R, Smego RA Jr, Am J Trop Med Hyg 2002 67 230 232 12408660
4. The pathophysiology of vivax malaria. Anstey NM, Russell B, Yeo TW, Price RN, Trends Parasitol 2009 25 220 227 10.1016/j.pt.2009.02.003 19349210
5. Resistance to therapies for infection by Plasmodium vivax. Baird JK, Clin Microbiol Rev 2009 22 508 534 10.1128/CMR.00008-09 19597012
6. 1912-2012: a century of research on Plasmodium vivax in vitro culture. Noulin F, Borlon C, Van Den Abbeele J, D'Alessandro U, Erhart A, Trends Parasitol 2013 29 286 294 10.1016/j.pt.2013.03.012 23623759
7. A highly infective Plasmodium vivax strain adapted to Aotus monkeys: quantitative haematological and molecular determinations useful for P. vivax malaria vaccine development. Pico De Coana Y, Rodriguez J, Guerrero E, Barrero C, Rodriguez R, Mendoza M, Patarroyo MA, Vaccine 2003 21 3930 3937 10.1016/S0264-410X(03)00278-0 12922128
8. PvRON2, a new Plasmodium vivax rhoptry neck antigen. Arevalo-Pinzon G, Curtidor H, Patino LC, Patarroyo MA, Malar J 2011 10 60 10.1186/1475-2875-10-60 21401956
9. Identifying and characterising the Plasmodium falciparum RhopH3 Plasmodium vivax homologue. Mongui A, Perez-Leal O, Rojas-Caraballo J, Angel DI, Cortes J, Patarroyo MA, Biochem Biophys Res Commun 2007 358 861 866 10.1016/j.bbrc.2007.05.015 17511961
10. The GPI-anchored 6-Cys protein Pv12 is present in detergent-resistant microdomains of Plasmodium vivax blood stage schizonts. Moreno-Perez DA, Areiza-Rojas R, Florez-Buitrago X, Silva Y, Patarroyo ME, Patarroyo MA, Protist 2013 164 37 48 10.1016/j.protis.2012.03.001 22554829
11. Identifying and characterizing a member of the RhopH1/Clag family in Plasmodium vivax. Moreno-Perez DA, Mongui A, Soler LN, Sanchez-Ladino M, Patarroyo MA, Gene 2011 481 17 23 10.1016/j.gene.2011.03.007 21513780
12. The cellular and molecular basis for malaria parasite invasion of the human red blood cell. Cowman AF, Berry D, Baum J, J Cell Biol 2012 198 961 971 10.1083/jcb.201206112 22986493
13. Host-cell invasion by malaria parasites: insights from Plasmodium and Toxoplasma. Baum J, Gilberger TW, Frischknecht F, Meissner M, Trends Parasitol 2008 24 557 563 10.1016/j.pt.2008.08.006 18835222
14. Secretion from the rhoptries of Toxoplasma gondii during host-cell invasion. Nichols BA, Chiappino ML, O'Connor GR, J Ultrastruct Res 1983 83 85 98 10.1016/S0022-5320(83)90067-9 6854716
15. Rhoptry secretion of membranous whorls by Plasmodium falciparum merozoites. Stewart MJ, Schulman S, Vanderberg JP, Am J Trop Med Hyg 1986 35 37 44 3511750
16. Proteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii. Bradley PJ, Ward C, Cheng SJ, Alexander DL, Coller S, Coombs GH, Dunn JD, Ferguson DJ, Sanderson SJ, Wastling JM, Boothroyd JC, J Biol Chem 2005 280 34245 34258 10.1074/jbc. M504158200 16002398
17. Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites. Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Gao Q, Tsuboi T, Torii M, Parasitol Int 2009 58 29 35 10.1016/j.parint.2008.09.005 18952195
18. Plasmodium falciparum: genetic and immunogenic characterisation of the rhoptry neck protein PfRON4. Morahan BJ, Sallmann GB, Huestis R, Dubljevic V, Waller KL, Exp Parasitol 2009 122 280 288 10.1016/j.exppara.2009.04.013 19442663
19. Identification of the Plasmodium falciparum rhoptry neck protein 5 (PfRON5). Curtidor H, Patino LC, Arevalo-Pinzon G, Patarroyo ME, Patarroyo MA, Gene 2011 474 22 28 10.1016/j.gene.2010.12.005 21185360
20. An inhibitory antibody blocks interactions between components of the malarial invasion machinery. Collins CR, Withers-Martinez C, Hackett F, Blackman MJ, PLoS Pathog 2009 5 1000273 10.1371/journal.ppat.1000273 19165323
21. Structural and functional insights into the malaria parasite moving junction complex. Vulliez-Le Normand B, Tonkin ML, Lamarque MH, Langer S, Hoos S, Roques M, Saul FA, Faber BW, Bentley GA, Boulanger MJ, Lebrun M, PLoS Pathog 2012 8 1002755 10.1371/journal.ppat.1002755 22737069
22. Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion. Srinivasan P, Beatty WL, Diouf A, Herrera R, Ambroggio X, Moch JK, Tyler JS, Narum DL, Pierce SK, Boothroyd JC, Haynes JD, Miller LH, Proc Natl Acad Sci USA 2011 108 13275 13280 10.1073/pnas.1110303108 21788485
23. The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites. Lamarque M, Besteiro S, Papoin J, Roques M, Vulliez-Le Normand B, Morlon-Guyot J, Dubremetz JF, Fauquenoy S, Tomavo S, Faber BW, Kocken CH, Thomas AW, Boulanger MJ, Bentley GA, Lebrun M, PLoS Pathog 2011 7 1001276 10.1371/journal.ppat.1001276 21347343
24. Independent roles of apical membrane antigen 1 and rhoptry neck proteins during host cell invasion by apicomplexa. Giovannini D, Spath S, Lacroix C, Perazzi A, Bargieri D, Lagal V, Lebugle C, Combe A, Thiberge S, Baldacci P, Tardieux I, Menard R, Cell Host Microbe 2011 10 591 602 10.1016/j.chom.2011.10. 012 22177563
25. Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte. Riglar DT, Richard D, Wilson DW, Boyle MJ, Dekiwadia C, Turnbull L, Angrisano F, Marapana DS, Rogers KL, Whitchurch CB, Beeson JG, Cowman AF, Ralph SA, Baum J, Cell Host Microbe 2011 9 9 20 10.1016/j.chom.2010.12.003 21238943
26. Fragments of the polymorphic Mr 185,000 glycoprotein from the surface of isolated Plasmodium falciparum merozoites form an antigenic complex. McBride JS, Heidrich HG, Mol Biochem Parasitol 1987 23 71 84 10.1016/0166-6851(87)90189-7 2437453
27. Novel components of the Apicomplexan moving junction reveal conserved and coccidia-restricted elements. Straub KW, Cheng SJ, Sohn CS, Bradley PJ, Cell Microbiol 2009 11 590 603 10.1111/j.1462-5822.2008.01276.x 19134112
28. Prediction of complete gene structures in human genomic DNA. Burge C, Karlin S, J Mol Biol 1997 268 78 94 10.1006/jmbi.1997.0951 9149143
29. Spidey http://www.ncbi.nlm.nih.gov/spidey/
30. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Nielsen H, Engelbrecht J, Brunak S, von Heijne G, Protein Eng 1997 10 1 6 10.1093/protein/10.1.1 9239223
31. An HMM posterior decoder for sequence feature prediction that includes homology information. Kall L, Krogh A, Sonnhammer EL, Bioinformatics 2005 21 Suppl 1 251 257 10.1093/bioinformatics/bti1014 15961464
32. Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. Krogh A, Larsson B, von Heijne G, Sonnhammer EL, J Mole Biol 2001 305 567 580 10.1006/jmbi.2000.4315
33. PredGPI: a GPI-anchor predictor. Pierleoni A, Martelli PL, Casadio R, BMC Bioinformatics 2008 9 392 10.1186/1471-2105-9-392 18811934
34. Recent improvements to the SMART domain-based sequence annotation resource. Letunic I, Goodstadt L, Dickens NJ, Doerks T, Schultz J, Mott R, Ciccarelli F, Copley RR, Ponting CP, Bork P, Nucleic Acids Res 2002 30 242 244 10.1093/nar/30.1.242 11752305
35. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Chomczynski P, Biotechniques 1993 15 532 534 536-537 7692896
36. Identification, characterization and antigenicity of the Plasmodium vivax rhoptry neck protein 1 (PvRON1). Moreno-Perez DA, Montenegro M, Patarroyo ME, Patarroyo MA, Malar J 2011 10 314 10.1186/1475-2875-10-314 22024312
37. The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum. Neafsey DE, Galinsky K, Jiang RH, Young L, Sykes SM, Saif S, Gujja S, Goldberg JM, Young S, Zeng Q, Chapman SB, Dash AP, Anvikar AR, Sutton PL, Birren BW, Escalante AA, Barnwell JW, Carlton JM, Nat Genet 2012 44 1046 1050 10.1038/ng.2373 22863733
38. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Thompson JD, Higgins DG, Gibson TJ, Nucleic Acids Res 1994 22 4673 4680 10.1093/nar/22.22.4673 7984417
39. ANTHEPROT: an interactive graphics software for analyzing protein structures from sequences. Geourjon C, Deleage G, Roux B, J Mol Graph 1991 9 188 190 167 10.1016/0263-7855(91)80008-N 1772842
40. Improved method for predicting linear B-cell epitopes. Larsen JE, Lund O, Nielsen M, Immunome Res 2006 2 2 10.1186/1745-7580-2-2 16635264
41. Phylogeny of the malarial genus Plasmodium, derived from rRNA gene sequences. Escalante AA, Ayala FJ, Proc Natl Acad Sci USA 1994 91 11373 11377 10.1073/pnas.91.24.11373 7972067
42. The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. Bozdech Z, Llinas M, Pulliam BL, Wong ED, Zhu J, DeRisi JL, PLoS Biol 2003 1 5 12929205
43. A proteomic view of the Plasmodium falciparum life cycle. Florens L, Washburn MP, Raine JD, Anthony RM, Grainger M, Haynes JD, Moch JK, Muster N, Sacci JB, Tabb DL, Witney AA, Wolters D, Wu Y, Gardner MJ, Holder AA, Sinden RE, Yates JR, Carucci DJ, Nature 2002 419 520 526 10.1038/nature01107 12368866
44. Structure of the gene encoding the immunodominant surface antigen on the sporozoite of the human malaria parasite Plasmodium falciparum. Dame JB, Williams JL, McCutchan TF, Weber JL, Wirtz RA, Hockmeyer WT, Maloy WL, Haynes JD, Schneider I, Roberts D, Sanders GS, Reddy EP, Diggs CL, Miller LH, Science 1984 225 593 599 10.1126/science.6204383 6204383
45. Protein variation in clones of Plasmodium falciparum detected by two dimensional electrophoresis. Fenton B, Walker A, Walliker D, Mol Biochem Parasitol 1985 16 173 183 10.1016/0166-6851(85)90085-4 3897860
46. Malaria: immune evasion by parasites. Hisaeda H, Yasutomo K, Himeno K, Int J Biochem Cell Biol 2005 37 700 706 10.1016/j.biocel.2004.10.009 15694829
47. Export of a Toxoplasma gondii rhoptry neck protein complex at the host cell membrane to form the moving junction during invasion. Besteiro S, Michelin A, Poncet J, Dubremetz JF, Lebrun M, PLoS Pathog 2009 5 1000309 10.1371/journal.ppat.1000309 19247437
48. Dissecting the apicomplexan rhoptry neck proteins. Proellocks NI, Coppel RL, Waller KL, Trends Parasitol 2010 26 297 304 10.1016/j.pt.2010.02.012 20347614
49. Interactions between merozoite surface proteins 1, 6, and 7 of the malaria parasite Plasmodium falciparum. Kauth CW, Woehlbier U, Kern M, Mekonnen Z, Lutz R, Mucke N, Langowski J, Bujard H, J Biol Chem 2006 281 31517 31527 10.1074/jbc.M604641200 16940297
50. Extensive proteolytic processing of the malaria parasite merozoite surface protein 7 during biosynthesis and parasite release from erythrocytes. Pachebat JA, Kadekoppala M, Grainger M, Dluzewski AR, Gunaratne RS, Scott-Finnigan TJ, Ogun SA, Ling IT, Bannister LH, Taylor HM, Mitchell GH, Holder AA, Mol Biochem Parasitol 2007 151 59 69 10.1016/j.molbiopara.2006.10.006 17097159
51. The rhoptry neck protein RON4 re-localizes at the moving junction during Toxoplasma gondii invasion. Lebrun M, Michelin A, El Hajj H, Poncet J, Bradley PJ, Vial H, Dubremetz JF, Cell Microbiol 2005 7 1823 1833 10.1111/j.1462-5822. 2005.00646.x 16309467