Variation of types of alcoholism: Review and subtypes identified in Han Chinese

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 48, Issue , 2014, Pages 36-40

  Lee, Sheng Yu ^a,b   Chen, Shiou Lan ^a   Chang, Yun Hsuan ^a   Lu, Ru Band ^a,b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Alcoholism; ALDH2; DRD2; Genes; MAOA

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; DOPAMINE 2 RECEPTOR;

ALCOHOL ABUSE; ALCOHOL USE DISORDER; ALCOHOLISM; ALDH2 GENE; ANTISOCIAL PERSONALITY DISORDER; ANXIETY; ARTICLE; CHINESE; COMORBIDITY; DEPRESSION; DOPAMINE D2 RECEPTOR GENE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAOA GENE; MOLECULAR GENETICS; MULTIPLE DRUG ABUSE;

3,4-DIHYDROXYPHENYL-ACETALDEHYDE; 3,4-DIHYDROXYPHENYLACETIC ACID; ALC; ALCOHOLISM; ALDEHYDE DEHYDROGENASE 2; ALDH2; ANTISOCIAL ALC; ANTISOCIAL ALCOHOLISM; ANTISOCIAL NON-ALC; ANTISOCIAL NON-ALCOHOLISM; ANTISOCIAL PERSONALITY DISORDER; ANX/DEP ALC; ANXIETY/DEPRESSION ALCOHOLISM; ASPD; DOPAC; DOPAL; DOPAMINE D2 RECEPTOR; DRD2; GENES; HA; HARM AVOIDANCE; MAOA; METHYLENETETRAHYDROFOLATE REDUCTASE; MIXED ALC; MIXED ALCOHOLISM; MONOAMINE OXIDASE A; MTHFR; NOVELTY SEEKING; NS; PURE ALC; PURE ALCOHOLISM;

ALCOHOLISM; ALDEHYDE DEHYDROGENASE; ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MONOAMINE OXIDASE; RECEPTORS, DOPAMINE D2;

EID: 84884914144     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2013.09.013     Document Type: Review

References (74)

1. Amadeo S., Abbar M., Fourcade M.L., Waksman G., Leroux M.G., Madec A., et al. D2 dopamine receptor gene and alcoholism. J Psychiatr Res 1993, 27:173-179.
2. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorder-IV-TR 2000, American Psychiatric Association, Washington. 4th ed.
3. Babor T.F., Dolinsky Z.S., Meyer R.E., Hesselbrock M., Hofmann M., Tennen H. Types of alcoholics: concurrent and predictive validity of some common classification schemes. Br J Addict 1992, 87:1415-1431.
4. Belfrage H., Lidberg L., Oreland L. Platelet monoamine oxidase activity in mentally disordered violent offenders. Acta Psychiatr Scand 1992, 85:218-221.
5. Benyamina A., Saffroy R., Blecha L., Pham P., Karila L., Debuire B., et al. Association between MTHFR 677C-T polymorphism and alcohol dependence according to Lesch and Babor typology. Addict Biol 2009, 14:503-505.
6. Berglund K., Fahlke C., Berggren U., Eriksson M., Balldin J. Personality profile in type I alcoholism: long duration of alcohol intake and low serotonergic activity are predictive factors of anxiety proneness. J Neural Transm 2006, 113:1287-1298.
7. Blum K., Noble E.P., Sheridan P.J., Montgomery A., Ritchie T., Jagadeeswaran P., et al. Allelic association of human dopamine D2 receptor gene in alcoholism. JAMA 1990, 263:2055-2060.
8. Blum K., Noble E.P., Sheridan P.J., Finley O., Montgomery A., Ritchie T., et al. Association of the A1 allele of the D2 dopamine receptor gene with severe alcoholism. Alcohol 1991, 8:409-416.
9. Bolos A.M., Dean M., Lucas-Derse S., Ramsburg M., Brown G.L., Goldman D. Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism. JAMA 1990, 264:3156-3160.
10. Brodie M.S. Increased ethanol excitation of dopaminergic neurons of the ventral tegmental area after chronic ethanol treatment. Alcohol Clin Exp Res 2002, 26:1024-1030.
11. Brodie M.S., Shefner S.A., Dunwiddie T.V. Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro. Brain Res 1990, 508:65-69.
12. Brooner R.K., King V.L., Kidorf M., Schmidt C.W., Bigelow G.E. Psychiatric and substance use comorbidity among treatment-seeking opioid abusers. Arch Gen Psychiatry 1997, 54:71-80.
13. Brunner H.G., Nelen M.R., van Zandvoort P., Abeling N.G., van Gennip A.H., Wolters E.C., et al. X-linked borderline mental retardation with prominent behavioral disturbance: phenotype, genetic localization, and evidence for disturbed monoamine metabolism. Am J Hum Genet 1993, 52:1032-1039.
14. Caspi A., McClay J., Moffitt T.E., Mill J., Martin J., Craig I.W., et al. Role of genotype in the cycle of violence in maltreated children. Science 2002, 297:851-854.
15. Chen C.C., Lu R.B., Chen Y.C., Wang M.F., Chang Y.C., Li T.K., et al. Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism. Am J Hum Genet 1999, 65:795-807.
16. Cloninger C.R. Neurogenetic adaptive mechanisms in alcoholism. Science 1987, 236:410-416.
17. Conneally P.M. Association between the D2 dopamine receptor gene and alcoholism. A continuing controversy. Arch Gen Psychiatry 1991, 48:757-759.
18. Cotton N.S. The familial incidence of alcoholism: a review. J Stud Alcohol 1979, 40:89-116.
19. Curtis N.R., Kulagowski J.J., Leeson P.D., Ridgill M.P., Emms F., Freedman S.B., et al. Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands. Bioorg Med Chem Lett 1999, 9:585-588.
20. Dick D.M., Foroud T. Candidate genes for alcohol dependence: a review of genetic evidence from human studies. Alcohol Clin Exp Res 2003, 27:868-879.
21. Ducci F., Enoch M.A., Hodgkinson C., Xu K., Catena M., Robin R.W., et al. Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women. Mol Psychiatry 2008, 13:334-347.
22. Edenberg H.J., Foroud T., Koller D.L., Goate A., Rice J., Van Eerdewegh P., et al. A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism. Alcohol Clin Exp Res 1998, 22:505-512.
23. Ferguson R.A., Goldberg D.M. Genetic markers of alcohol abuse. Clin Chim Acta 1997, 257:199-250.
24. Gejman P.V., Ram A., Gelernter J., Friedman E., Cao Q., Pickar D., et al. No structural mutation in the dopamine D2 receptor gene in alcoholism or schizophrenia. Analysis using denaturing gradient gel electrophoresis. JAMA 1994, 271:204-208.
25. Gelernter J., O'Malley S., Risch N., Kranzler H.R., Krystal J., Merikangas K., et al. No association between an allele at the D2 dopamine receptor gene (DRD2) and alcoholism. JAMA 1991, 266:1801-1807.
26. Goldman D. Candidate genes in alcoholism. Clin Neurosci 1995, 3:174-181.
27. Goodwin R.D., Hamilton S.P. Lifetime comorbidity of antisocial personality disorder and anxiety disorders among adults in the community. Psychiatry Res 2003, 117:159-166.
28. Goodwin D.W., Schulsinger F., Hermansen L., Guze S.B., Winokur G. Alcohol problems in adoptees raised apart from alcoholic biological parents. Arch Gen Psychiatry 1973, 28:238-243.
29. Hietala J., West C., Syvalahti E., Nagren K., Lehikoinen P., Sonninen P., et al. Striatal D2 dopamine receptor binding characteristics in vivo in patients with alcohol dependence. Psychopharmacology (Berl) 1994, 116:285-290.
30. Hu M.C., Lee S.Y., Wang T.Y., Chen S.L., Chang Y.H., Chen S.H., et al. Association study of DRD2 and MAOA genes with subtyped alcoholism comorbid with bipolar disorder in Han Chinese. Prog Neuropsychopharmacol Biol Psychiatry 2013, 40:144-148.
31. Huang S.Y., Lin W.W., Ko H.C., Lee J.F., Wang T.J., Chou Y.H., et al. Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence. Alcohol Clin Exp Res 2004, 28:374-384.
32. Huang S.Y., Lin W.W., Wan F.J., Chang A.J., Ko H.C., Wang T.J., et al. Monoamine oxidase-A polymorphisms might modify the association between the dopamine D2 receptor gene and alcohol dependence. J Psychiatry Neurosci 2007, 32:185-192.
33. Huang S.Y., Lu R.B., Ma K.H., Shy M.J., Lin W.W. Norepinephrine transporter polymorphisms T-182C and G1287A are not associated with alcohol dependence and its clinical subgroups. Drug Alcohol Depend 2008, 92:20-26.
34. Hwu H.G., Yeh E.K., Yeh Y.L., Chang L.Y. Alcoholism by Chinese diagnostic interview schedule: a prevalence and validity study. Acta Psychiatr Scand 1988, 77:7-13.
35. Jellinek E.M., Efron V., Keller M. The Classified Abstract Archive of the Alcohol Literature. II. The code dictionary. Q J Stud Alcohol 1953, 14:285-311.
36. Jonsson E.G., Nothen M.M., Grunhage F., Farde L., Nakashima Y., Propping P., et al. Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers. Mol Psychiatry 1999, 4:290-296.
37. Kapur J., Macdonald R.L. Cyclic AMP-dependent protein kinase enhances hippocampal dentate granule cell GABAA receptor currents. J Neurophysiol 1996, 76:2626-2634.
38. Kendler K.S., Heath A.C., Neale M.C., Kessler R.C., Eaves L.J. A population-based twin study of alcoholism in women. JAMA 1992, 268:1877-1882.
39. Keung W.M., Vallee B.L. Daidzin and its antidipsotropic analogs inhibit serotonin and dopamine metabolism in isolated mitochondria. Proc Natl Acad Sci USA 1998, 95:2198-2203.
40. Kidorf M., Disney E.R., King V.L., Neufeld K., Beilenson P.L., Brooner R.K. Prevalence of psychiatric and substance use disorders in opioid abusers in a community syringe exchange program. Drug Alcohol Depend 2004, 74:115-122.
41. Kremer I., Bachner-Melman R., Reshef A., Broude L., Nemanov L., Gritsenko I., et al. Association of the serotonin transporter gene with smoking behavior. Am J Psychiatry 2005, 162:924-930.
42. Lee S.Y., Hahn C.Y., Lee J.F., Chen S.L., Chen S.H., Yeh T.L., et al. MAOA-uVNTR polymorphism may modify the protective effect of ALDH2 gene against alcohol dependence in antisocial personality disorder. Alcohol Clin Exp Res 2009, 33:985-990.
43. Lee S.Y., Hahn C.Y., Lee J.F., Huang S.Y., Chen S.L., Kuo P.H., et al. MAOA interacts with the ALDH2 gene in anxiety-depression alcohol dependence. Alcohol Clin Exp Res 2010, 34:1212-1218.
44. Lesch O.M., Dietzel M., Musalek M., Walter H., Zeiler K. The course of alcoholism. Long-term prognosis in different types. Forensic Sci Int 1988, 36:121-138.
45. Lu X., Tao M., Luo J., Geng Y., Zhao H., Zhao P. Epidemiology of alcohol and liver disease. Zhonghua Gan Zang Bing Za Zhi 2002, 10:467-468.
46. Lu R.B., Lin W.W., Lee J.F., Ko H.C., Shih J.C. Neither antisocial personality disorder nor antisocial alcoholism is associated with the MAO-A gene in Han Chinese males. Alcohol Clin Exp Res 2003, 27:889-893.
47. Lu R.B., Ko H.C., Lee J.F., Lin W.W., Huang S.Y., Wang T.J., et al. No alcoholism-protection effects of ADH1B*2 allele in antisocial alcoholics among Han Chinese in Taiwan. Alcohol Clin Exp Res 2005, 29:2101-2107.
48. Lu R.B., Lee J.F., Huang S.Y., Lee S.Y., Chang Y.H., Kuo P.H., et al. Interaction between ALDH2*1*1 and DRD2/ANKK1 TaqI A1A1 genes may be associated with antisocial personality disorder not co-morbid with alcoholism. Addict Biol 2012, 17:865-874.
49. McBride W.J., Chernet E., Dyr W., Lumeng L., Li T.K. Densities of dopamine D2 receptors are reduced in CNS regions of alcohol-preferring P rats. Alcohol 1993, 10:387-390.
50. Merikangas K.R. The genetic epidemiology of alcoholism. Psychol Med 1990, 20:11-22.
51. Morey L.C., Skinner H.A. Empirically derived classifications of alcohol-related problems. Recent Dev Alcohol 1986, 4:145-168.
52. Munafo M.R., Matheson I.J., Flint J. Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication bias. Mol Psychiatry 2007, 12:454-461.
53. Noble E.P. Polymorphisms of the D2 dopamine receptor gene and alcoholism and other substance use disorders. Alcohol Alcohol Suppl 1994, 2:35-43.
54. Noble E.P., Blum K., Ritchie T., Montgomery A., Sheridan P.J. Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism. Arch Gen Psychiatry 1991, 48:648-654.
55. Noble E.P., Zhang X., Ritchie T.L., Sparkes R.S. Haplotypes at the DRD2 locus and severe alcoholism. Am J Med Genet 2000, 96:622-631.
56. Parsian A. Sequence analysis of exon 8 of MAO-A gene in alcoholics with antisocial personality and normal controls. Genomics 1999, 55:290-295.
57. Parsian A., Todd R.D., Devor E.J., O'Malley K.L., Suarez B.K., Reich T., et al. Alcoholism and alleles of the human D2 dopamine receptor locus. Studies of association and linkage. Arch Gen Psychiatry 1991, 48:655-663.
58. Pickens R.W., Svikis D.S., McGue M., Lykken D.T., Heston L.L., Clayton P.J. Heterogeneity in the inheritance of alcoholism. A study of male and female twins. Arch Gen Psychiatry 1991, 48:19-28.
59. Pohjalainen T., Rinne J.O., Nagren K., Lehikoinen P., Anttila K., Syvalahti E.K., et al. The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers. Mol Psychiatry 1998, 3:256-260.
60. Prisco S., Pagannone S., Esposito E. Serotonin-dopamine interaction in the rat ventral tegmental area: an electrophysiological study in vivo. J Pharmacol Exp Ther 1994, 271:83-90.
61. Reich T., Hinrichs A., Culverhouse R., Bierut L. Genetic studies of alcoholism and substance dependence. Am J Hum Genet 1999, 65:599-605.
62. Samochowiec J., Lesch K.P., Rottmann M., Smolka M., Syagailo Y.V., Okladnova O., et al. Association of a regulatory polymorphism in the promoter region of the monoamine oxidase A gene with antisocial alcoholism. Psychiatry Res 1999, 86:67-72.
63. Schmidt L.G., Sander T., Kuhn S., Smolka M., Rommelspacher H., Samochowiec J., et al. Different allele distribution of a regulatory MAOA gene promoter polymorphism in antisocial and anxious-depressive alcoholics. J Neural Transm 2000, 107:681-689.
64. Stefanini E., Frau M., Garau M.G., Garau B., Fadda F., Gessa G.L. Alcohol-preferring rats have fewer dopamine D2 receptors in the limbic system. Alcohol Alcohol 1992, 27:127-130.
65. Suarez B.K., Parsian A., Hampe C.L., Todd R.D., Reich T., Cloninger C.R. Linkage disequilibria at the D2 dopamine receptor locus (DRD2) in alcoholics and controls. Genomics 1994, 19:12-20.
66. Thomasson H.R., Edenberg H.J., Crabb D.W., Mai X.L., Jerome R.E., Li T.K., et al. Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am J Hum Genet 1991, 48:677-681.
67. Tomer R., Aharon-Peretz J. Novelty seeking and harm avoidance in Parkinson's disease: effects of asymmetric dopamine deficiency. J Neurol Neurosurg Psychiatry 2004, 75:972-975.
68. Turner E., Ewing J., Shilling P., Smith T.L., Irwin M., Schuckit M., et al. Lack of association between an RFLP near the D2 dopamine receptor gene and severe alcoholism. Biol Psychiatry 1992, 31:285-290.
69. van den Bree M.B.M., Svikis D.S., Pickens R.W. Genetic influences in antisocial personality and drug use disorders. Drug Alcohol Depend 1998, 49:177-187.
70. Waldman I.D., Robinson B.F., Rhee S.H. A logistic regression extension of the transmission disequilibrium test for continuous traits: application to linkage disequilibrium between alcoholism and the candidate genes DRD2 and ADH3. Genet Epidemiol 1999, 17(Suppl. 1):S379-S384.
71. Wang T.J., Huang S.Y., Lin W.W., Lo H.Y., Wu P.L., Wang Y.S., et al. Possible interaction between MAOA and DRD2 genes associated with antisocial alcoholism among Han Chinese men in Taiwan. Prog Neuropsychopharmacol Biol Psychiatry 2007, 31:108-114.
72. Wang T.Y., Lee S.Y., Chen S.L., Chang Y.H., Chen S.H., Chu C.H., et al. The ADH1B and DRD2 gene polymorphism may modify the protective effect of the ALDH2 gene against heroin dependence. Prog Neuropsychopharmacol Biol Psychiatry 2013, 43:134-139.
73. Westerink B.H., de Vries J.B. On the origin of dopamine and its metabolite in predominantly noradrenergic innervated brain areas. Brain Res 1985, 330:164-166.
74. Zucker D.K., Austin F., Fair A., Branchey L. Associations between patient religiosity and alcohol attitudes and knowledge in an alcohol treatment program. Int J Addict 1987, 22:47-53.