메뉴 건너뛰기




Volumn 4, Issue 3, 1999, Pages 290-296

Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers

Author keywords

Association; DRD2; PET; Polymorphisms; Receptor binding; 11C raclopride

Indexed keywords

BRAIN RECEPTOR; CARBON 11; DOPAMINE 2 RECEPTOR; RACLOPRIDE;

EID: 0033009871     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000532     Document Type: Article
Times cited : (637)

References (45)
  • 2
    • 0025923342 scopus 로고
    • Allelic association of the D2 dopamine receptor gene: With receptor-binding characteristics in alcoholism
    • 2 Noble EP. Blum K, Ritchie T, Montgomery A, Sheridan PJ. Allelic association of the D2 dopamine receptor gene: with receptor-binding characteristics in alcoholism. Arch Gen Psychiatry 1991; 48: 648-654.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 648-654
    • Noble, E.P.1    Blum, K.2    Ritchie, T.3    Montgomery, A.4    Sheridan, P.J.5
  • 3
    • 0031752522 scopus 로고    scopus 로고
    • The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers
    • 3 Pohjalainen T, Rinne JO, Någren K, Lehikoinen P, Anttila K, Syvälahti EKG et al. The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers. Mol Psychiatry 1998; 3: 256-260.
    • (1998) Mol Psychiatry , vol.3 , pp. 256-260
    • Pohjalainen, T.1    Rinne, J.O.2    Någren, K.3    Lehikoinen, P.4    Anttila, K.5    Syvälahti, E.K.G.6
  • 4
    • 9844233161 scopus 로고    scopus 로고
    • D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: Reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele
    • 4 Thompson J, Thomas N, Singleton A, Piggott M, Lloyd S, Perry EK et al. D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele. Pharmacogenetics 1997; 7: 479-484.
    • (1997) Pharmacogenetics , vol.7 , pp. 479-484
    • Thompson, J.1    Thomas, N.2    Singleton, A.3    Piggott, M.4    Lloyd, S.5    Perry, E.K.6
  • 5
    • 0031036194 scopus 로고    scopus 로고
    • D2 dopamine receptors and personality traits
    • 5 Farde L, Gustavsson JP. Jönsson E. D2 dopamine receptors and personality traits. Nature 1997; 385: 590.
    • (1997) Nature , vol.385 , pp. 590
    • Farde, L.1    Gustavsson, J.P.2    Jönsson, E.3
  • 6
    • 0026718710 scopus 로고
    • Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine
    • 6 Farde L, Nordström A-L, Wiesel F-A, Pauli S, Halldin C, Sedvall G, Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Arch Gen Psychiatry 1992; 49: 538-544.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 538-544
    • Farde, L.1    Nordström, A.-L.2    Wiesel, F.-A.3    Pauli, S.4    Halldin, C.5    Sedvall, G.6
  • 9
    • 0030889597 scopus 로고    scopus 로고
    • Quantification of neuroreceptors in the living human brain: III. D2-like dopamine receptors: Theory, validation, and changes during normal aging
    • 9 Wong DF, Young D, Wilson PD, Meltzer CC, Gjedde A. Quantification of neuroreceptors in the living human brain: III. D2-like dopamine receptors: theory, validation, and changes during normal aging. J Cereb Blood Flow Metab 1997; 17: 316-330.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 316-330
    • Wong, D.F.1    Young, D.2    Wilson, P.D.3    Meltzer, C.C.4    Gjedde, A.5
  • 10
    • 0023634210 scopus 로고
    • In vivo measurement of dopamine receptors in human brain by positron emission tomography. Age and sex differences
    • 10 Wong DF, Broussolle EP, Wand G, Villemagne V, Dannals RF, Links JM et al. In vivo measurement of dopamine receptors in human brain by positron emission tomography. Age and sex differences. Ann N Y Acad Sci 1088; 515: 203-214.
    • (1088) Ann N Y Acad Sci , vol.515 , pp. 203-214
    • Wong, D.F.1    Broussolle, E.P.2    Wand, G.3    Villemagne, V.4    Dannals, R.F.5    Links, J.M.6
  • 11
    • 0028171946 scopus 로고
    • Striatal D2 dopamine receptor binding charachteristics in vivo in patients with alcohol dependence
    • 11 Hietala J, West C, Syvälahti E, Någren K, Lehikoinen P, Sonninen P et al. Striatal D2 dopamine receptor binding charachteristics in vivo in patients with alcohol dependence. Psychopharmacology 1994; 116: 285-290.
    • (1994) Psychopharmacology , vol.116 , pp. 285-290
    • Hietala, J.1    West, C.2    Syvälahti, E.3    Någren, K.4    Lehikoinen, P.5    Sonninen, P.6
  • 13
    • 0030891225 scopus 로고    scopus 로고
    • Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects
    • 13 Volkow ND, Wang GJ, Fowler JS, Logan J, Gatley SJ, Hilzemann R et al. Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature 1997; 386: 830-833.
    • (1997) Nature , vol.386 , pp. 830-833
    • Volkow, N.D.1    Wang, G.J.2    Fowler, J.S.3    Logan, J.4    Gatley, S.J.5    Hilzemann, R.6
  • 14
    • 0027336093 scopus 로고
    • Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers
    • 14 Volkow ND, Fowler JS, Wang GJ, Hitzemann R, Logan J, Schlyer DJ et al. Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse. 1993; 14: 169-177.
    • (1993) Synapse , vol.14 , pp. 169-177
    • Volkow, N.D.1    Fowler, J.S.2    Wang, G.J.3    Hitzemann, R.4    Logan, J.5    Schlyer, D.J.6
  • 15
    • 0031060799 scopus 로고    scopus 로고
    • Dopamine D2 receptor availability in opiate-dependent subjects before and after naloxone-precipitated withdrawal
    • 15 Wang GJ, Volkow ND, Fowler JS, Logan J, Abumrad NN, Hitzemann KJ et al. Dopamine D2 receptor availability in opiate-dependent subjects before and after naloxone-precipitated withdrawal. Neuropsychopharmacology 1997; 16: 174-182.
    • (1997) Neuropsychopharmacology , vol.16 , pp. 174-182
    • Wang, G.J.1    Volkow, N.D.2    Fowler, J.S.3    Logan, J.4    Abumrad, N.N.5    Hitzemann, K.J.6
  • 16
    • 0027218298 scopus 로고
    • Pharmaacokinetics of cocaine: II. Mesocorticolimbic and striatal dopamine and cocaine receptors in C57BL and DBA mice
    • 16 Erwin VG, Womer DE, Campbell AD, Jones BC. Pharmaacokinetics of cocaine: II. Mesocorticolimbic and striatal dopamine and cocaine receptors in C57BL and DBA mice. Pharmacogenetics 1993; 3: 189-190.
    • (1993) Pharmacogenetics , vol.3 , pp. 189-190
    • Erwin, V.G.1    Womer, D.E.2    Campbell, A.D.3    Jones, B.C.4
  • 17
    • 0019415681 scopus 로고
    • The effect of haloperidol feeding on dopamine receptor number in ten mouse strains
    • 17 Belmaker RH, Bannet J, Brecher-Friede E, Yanai J, Ebstein RP. The effect of haloperidol feeding on dopamine receptor number in ten mouse strains. Clin Genet 1981; 19: 353-356.
    • (1981) Clin Genet , vol.19 , pp. 353-356
    • Belmaker, R.H.1    Bannet, J.2    Brecher-Friede, E.3    Yanai, J.4    Ebstein, R.P.5
  • 18
    • 0020032854 scopus 로고
    • Genetic regulation of neurotransmitters enzyme and receptors: Relationship to the inheritance of psychiatric disorders
    • 18 Ciaranello RE, Boehme R. Genetic regulation of neurotransmitters enzyme and receptors: relationship to the inheritance of psychiatric disorders. Behav Genet 1982; 12; 11-35.
    • (1982) Behav Genet , vol.12 , pp. 11-35
    • Ciaranello, R.E.1    Boehme, R.2
  • 19
    • 0020368412 scopus 로고
    • Genetic control of dopamine receptors in mouse caudate-nucleus: Relationship on cataleptic response to neuroleptic drugs
    • 19 Fink JS. Swerdloff A, Reis DJ, Genetic control of dopamine receptors in mouse caudate-nucleus: relationship on cataleptic response to neuroleptic drugs. Neurosci Lett 1982; 32: 301-306.
    • (1982) Neurosci Lett , vol.32 , pp. 301-306
    • Fink, J.S.1    Swerdloff, A.2    Reis, D.J.3
  • 20
    • 0021011845 scopus 로고
    • Genetic differences in brain dopamine receptors and amphetamine responses: Possible model for hyperkinetic children
    • 20 Helmeste DM, Seeman P. Genetic differences in brain dopamine receptors and amphetamine responses: possible model for hyperkinetic children. Prog Clin Biol Res 1983; 135: 401-403.
    • (1983) Prog Clin Biol Res , vol.135 , pp. 401-403
    • Helmeste, D.M.1    Seeman, P.2
  • 21
    • 0020415045 scopus 로고
    • Dopamine receptors in the striatum and limbic system of various strains of mice: Relation to differences in responses to apomorphine
    • 21 Michaluk J, Antkiewicz-Michaluk L, Rokosz-Pelc A, Sansone M, Oliverio A, Vetulani J. Dopamine receptors in the striatum and limbic system of various strains of mice: relation to differences in responses to apomorphine. Pharmocol Biochem Beahv 1982; 17: 1115-1118.
    • (1982) Pharmocol Biochem Beahv , vol.17 , pp. 1115-1118
    • Michaluk, J.1    Antkiewicz-Michaluk, L.2    Rokosz-Pelc, A.3    Sansone, M.4    Oliverio, A.5    Vetulani, J.6
  • 22
    • 0024158072 scopus 로고
    • Comparison of the density and distribution of brain D-1 and D-2 dopamine receptors in Buffalo vs fischer 344 rats
    • 22 Kerr LM, Unis AS, Wamsley JK. Comparison of the density and distribution of brain D-1 and D-2 dopamine receptors in Buffalo vs Fischer 344 rats. Phamiucol Biochem Behav 1988; 30: 325-330.
    • (1988) Phamiucol Biochem Behav , vol.30 , pp. 325-330
    • Kerr, L.M.1    Unis, A.S.2    Wamsley, J.K.3
  • 23
    • 0020606144 scopus 로고
    • Spontaneous and apomorphine-indnced locomotor changes parallel dopamine receptor differences in two rat strains
    • 23 Helmeste DM. Spontaneous and apomorphine-indnced locomotor changes parallel dopamine receptor differences in two rat strains. Pharmacol Biochem Behav 1983; 19: 153-155.
    • (1983) Pharmacol Biochem Behav , vol.19 , pp. 153-155
    • Helmeste, D.M.1
  • 24
    • 0022555951 scopus 로고
    • Selective dopamine D2 receptor reduction enhances a D1-mediated oral dyskinesia in rats
    • 24 Rosengarten H, Schweitzer JW. Friedhoff AJ. Selective dopamine D2 receptor reduction enhances a D1-mediated oral dyskinesia in rats. Life Sci 1986; 39: 29-35.
    • (1986) Life Sci , vol.39 , pp. 29-35
    • Rosengarten, H.1    Schweitzer, J.W.2    Friedhoff, A.J.3
  • 25
    • 0031596425 scopus 로고    scopus 로고
    • The regulation of DZ dopamine receptor expression
    • 25 Hilzemann RJ. The regulation of DZ dopamine receptor expression. Mol Psychiatry 1998; 3: 198-203.
    • (1998) Mol Psychiatry , vol.3 , pp. 198-203
    • Hilzemann, R.J.1
  • 27
    • 0031555874 scopus 로고    scopus 로고
    • Antagonist binding characteristics of the Ser311-Cys variant of human dopamine D2 receptor in vivo and vitro
    • 27 Pohjalainen T, Cravchik A, Gejman PV, Rinne J, Någren K, Syvalahti E et al. Antagonist binding characteristics of the Ser311-Cys variant of human dopamine D2 receptor in vivo and vitro. Biochem Biophys Res Commun 1997; 232: 143-146.
    • (1997) Biochem Biophys Res Commun , vol.232 , pp. 143-146
    • Pohjalainen, T.1    Cravchik, A.2    Gejman, P.V.3    Rinne, J.4    Någren, K.5    Syvalahti, E.6
  • 28
    • 0024448632 scopus 로고
    • 11C] raclopride binding to D2-dopamine receptors studied by PET - A comparison to the equilibrium analysis
    • 11C] raclopride binding to D2-dopamine receptors studied by PET - a comparison to the equilibrium analysis. J Cereb Blood Flow Metab 1989; 9: 696-708.
    • (1989) J Cereb Blood Flow Metab , vol.9 , pp. 696-708
    • Farde, L.1    Eriksson, L.2    Blomquist, G.3    Halldin, C.4
  • 29
    • 0030933979 scopus 로고    scopus 로고
    • A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia
    • 29 Arinami T, Gao M, Hamaguchi H, Torn M. A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia. Hum Mol Genet 1997; 6: 577-582.
    • (1997) Hum Mol Genet , vol.6 , pp. 577-582
    • Arinami, T.1    Gao, M.2    Hamaguchi, H.3    Torn, M.4
  • 31
    • 0031596430 scopus 로고    scopus 로고
    • D2 receptors binding potential is not affected by Taq1 polymorphism at the D2 receptor gene
    • 31 Laruelle M. Gelernter J, Innis RB. D2 receptors binding potential is not affected by Taq1 polymorphism at the D2 receptor gene. Mol Psychiatry 1998; 3: 261-265.
    • (1998) Mol Psychiatry , vol.3 , pp. 261-265
    • Laruelle, M.1    Gelernter, J.2    Innis, R.B.3
  • 33
    • 0027406130 scopus 로고
    • Reproducibility of repeated maesures of carbon-11-raclopride binding in the human brain
    • 33 Volkow N, Fowler J, Wang G, Dewey S, Schlyer D, MacGregor R et al. Reproducibility of repeated maesures of carbon-11-raclopride binding in the human brain. J Nucl Med 1993; 34; 609-613.
    • (1993) J Nucl Med , vol.34 , pp. 609-613
    • Volkow, N.1    Fowler, J.2    Wang, G.3    Dewey, S.4    Schlyer, D.5    MacGregor, R.6
  • 34
    • 0032127155 scopus 로고    scopus 로고
    • DRD2 allele frequencies and linkage disequilibria, including the -141C Ins/Del promoter polymorphism, in European-American, African-American, and Japanese subjects
    • 34 Gelernter J, Kranzler H, Cubells JF, Ichinose H, Nagatsu T. DRD2 allele frequencies and linkage disequilibria, including the -141C Ins/Del promoter polymorphism, in European-American, African-American, and Japanese subjects. Genomics 1998; 51: 21-26.
    • (1998) Genomics , vol.51 , pp. 21-26
    • Gelernter, J.1    Kranzler, H.2    Cubells, J.F.3    Ichinose, H.4    Nagatsu, T.5
  • 35
    • 0032527171 scopus 로고    scopus 로고
    • A PET study of D2 receptor density at different phases of the menstrual cycle
    • 35 Nordström A-L, Olsson H, Halldin C. A PET study of D2 receptor density at different phases of the menstrual cycle. Psychiatr Res (Neuroimag) 1998; 83: 1-6.
    • (1998) Psychiatr Res (Neuroimag) , vol.83 , pp. 1-6
    • Nordström, A.-L.1    Olsson, H.2    Halldin, C.3
  • 38
    • 0026612906 scopus 로고
    • Time course of D2-dopamine receptor occupancy examined by PET after single oral dosas of haloperidol
    • 38 Nordström A-L, Farde L, Halldin C. Time course of D2-dopamine receptor occupancy examined by PET after single oral dosas of haloperidol. Psychopharmacology 1992; 106: 433-438.
    • (1992) Psychopharmacology , vol.106 , pp. 433-438
    • Nordström, A.-L.1    Farde, L.2    Halldin, C.3
  • 39
    • 0027341623 scopus 로고
    • 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone
    • 39 Nyberg S, Farde L, Eriksson L, Halldin C, Eriksson B. 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology 1993; 110: 265-272.
    • (1993) Psychopharmacology , vol.110 , pp. 265-272
    • Nyberg, S.1    Farde, L.2    Eriksson, L.3    Halldin, C.4    Eriksson, B.5
  • 41
    • 0025415325 scopus 로고
    • Evaluation of the Karolinska new positron camera system; the Scanditrunix PC2048-25B
    • 41 Litton JE, Holte S, Eriksson L. Evaluation of the Karolinska new positron camera system; the Scanditrunix PC2048-25B. IEEE Trans Nucl Sci 1990; 37: 743-748.
    • (1990) IEEE Trans Nucl Sci , vol.37 , pp. 743-748
    • Litton, J.E.1    Holte, S.2    Eriksson, L.3
  • 45
    • 0027756690 scopus 로고
    • PCR detection of the TaqA RFLP at the DRD2 locus
    • 45 Grandy DK, Zhang Y, Civelli O. PCR detection of the TaqA RFLP at the DRD2 locus. Hum Mulec Genet 1993; 2: 2197.
    • (1993) Hum Molec Genet , vol.2 , pp. 2197
    • Grandy, D.K.1    Zhang, Y.2    Civelli, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.