Eosinophils are not required for the induction and maintenance of an alloantibody response

American Journal of Transplantation

Volumn 13, Issue 10, 2013, Pages 2696-2702

  Cravedi, P ^a   Lessman, D A ^a   Heeger, P S ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Donor specific antibodies; eosinophil; GATA 1; transplant

Indexed keywords

ALLOANTIBODY; GLYCOPROTEIN GP 130; TRANSCRIPTION FACTOR GATA 1;

ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EOSINOPHIL; FLOW CYTOMETRY; HEART TRANSPLANTATION; HETEROTOPIC TRANSPLANTATION; IMMUNIZATION; IN VIVO STUDY; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; RAT; SPLEEN CELL; THYMOCYTE;

DONOR-SPECIFIC ANTIBODIES; EOSINOPHIL; GATA-1; TRANSPLANT;

ANIMALS; ANTIBODY FORMATION; EOSINOPHILS; FLOW CYTOMETRY; GATA1 TRANSCRIPTION FACTOR; HEART TRANSPLANTATION; ISOANTIBODIES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PLASMA CELLS; TISSUE DONORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 84884910686     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12404     Document Type: Article

References (13)

1. Patel AM, Pancoska C, Mulgaonkar S, Weng FL., Renal transplantation in patients with pre-transplant donor-specific antibodies and negative flow cytometry crossmatches. Am J Transplant 2007; 7: 2371-2377.
2. Lefaucheur C, Loupy A, Hill GS, et al. Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation. J Am Soc Nephrol 2010; 21: 1398-1406.
3. Smith JD, Hamour IM, Banner NR, Rose ML., C4d fixing, luminex binding antibodies-A new tool for prediction of graft failure after heart transplantation. Am J Transplant 2007; 7: 2809-2815.
4. Akalin E, Pascual M., Sensitization after kidney transplantation. Clin J Am Soc Nephrol 2006; 1: 433-440.
5. Reinsmoen NL, Nelson K, Zeevi A., Anti-HLA antibody analysis and crossmatching in heart and lung transplantation. Transpl Immunol 2004; 13: 63-71.
6. Smith JD, Banner NR, Hamour IM, et al. De novo donor HLA-specific antibodies after heart transplantation are an independent predictor of poor patient survival. Am J Transplant 2011; 11: 312-319.
7. UNOS Database. Available at: http://www.unos.org. Accessed on April 9, 2013
8. Cassese G, Arce S, Hauser AE, et al. Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals. J Immunol 2003; 171: 1684-1690.
9. Belnoue E, Pihlgren M, McGaha TL, et al. APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells. Blood 2008; 111: 2755-2764.
10. Chu VT, Frohlich A, Steinhauser G, et al. Eosinophils are required for the maintenance of plasma cells in the bone marrow. Nat Immunol 2011; 12: 151-159.
11. Kwan WH, van der Touw W, Paz-Artal E, Li MO, Heeger PS., Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells. J Exp Med 2013; 210: 257-268.
12. Yu C, Cantor AB, Yang H, et al. Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo. J Exp Med 2002; 195: 1387-1395.
13. Zimmermann N, McBride ML, Yamada Y, et al. Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils. Allergy 2008; 63: 1156-1163.