Effects of Vitamin e on Bone Biomechanical and Histomorphometric Parameters in Ovariectomized Rats

Journal of Osteoporosis

Volumn 2013, Issue , 2013, Pages

  Feresin, Rafaela G ^a   Johnson, Sarah A ^a   Elam, Marcus L ^a   Kim, Jeong Su ^a   Khalil, Dania A ^a   Lucas, Edralin A ^b   Smith, Brenda J ^b   Payton, Mark E ^b   Akhter, Mohammed P ^c   Arjmandi, Bahram H ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA TOCOPHEROL;

ARTICLE; BIOMECHANICS; BODY WEIGHT; BONE DENSITY; BONE MINERALIZATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOSE RESPONSE; DRUG MEGADOSE; ENZYME ACTIVITY; FEMALE; FOOD INTAKE; LOW DRUG DOSE; LUMBAR VERTEBRA; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OVARIECTOMY; PRIORITY JOURNAL; RAT; TRABECULAR BONE; UTERUS WEIGHT;

EID: 84884866015     PISSN: 20908059     EISSN: 20420064     Source Type: Journal    
DOI: 10.1155/2013/825985     Document Type: Article

References (74)

1. Dixon J. M., Hormone replacement therapy and the breast. British Medical Journal 2001 323 7326 1381 1382 2-s2.0-0035893130 (Pubitemid 33152489)
2. Marcus R., Post-menopausal osteoporosis. Best Practice and Research 2002 16 3 309 327 2-s2.0-0036595261 10.1053/beog.2002.0284 (Pubitemid 41132045)
3. Barnes P. M., Powell-Griner E., McFann K., Nahin R. L., Complementary and alternative medicine use among adults: United States, 2002. Advance Data 2004 343 1 19 2-s2.0-3042576191
4. Stepan J. J., Pospichal J., Presl J., Pacovsky V., Bone loss and biochemical indices of bone remodeling in surgically induced postmenopausal women. Bone 1987 8 5 279 284 2-s2.0-0023545273 (Pubitemid 18013175)
5. Raisz L. G., Bone cell biology: new approaches and unanswered questions. Journal of Bone and Mineral Research 1993 8 supplement 2 S457 S465 2-s2.0-0027749459 (Pubitemid 24015230)
6. 2+ signaling pathway in osteoblasts. American Journal of Physiology-Cell Physiology 1998 274 6 C1686 C1698 2-s2.0-0031745219 (Pubitemid 28304207)
7. Traianedes K., Dallas M. R., Garrett I. R., Mundy G. R., Bonewald L. F., 5-lipoxygenase metabolites inhibit bone formation in vitro. Endocrinology 1998 139 7 3178 3184 2-s2.0-0031731091 10.1210/en.139.7.3178 (Pubitemid 28512347)
8. Manolagas S. C., Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocrine Reviews 2000 21 2 115 137 2-s2.0-0034455103 10.1210/er.21.2.115 (Pubitemid 32275592)
9. Cheleuitte D., Mizuno S., Glowacki J., In vitro secretion of cytokines by human bone marrow: effects of age and estrogen status. Journal of Clinical Endocrinology and Metabolism 1998 83 6 2043 2051 2-s2.0-0031732988 10.1210/jc.83.6.2043 (Pubitemid 28496335)
10. Walston J., Arking D. E., Fallin D., Li T., Beamer B., Xue Q., Ferrucci L., Fried L. P., Chakravarti A., IL-6 gene variation is not associated with increased serum levels of IL-6, muscle, weakness, or frailty in older women. Experimental Gerontology 2005 40 4 344 352 2-s2.0-16844384831 10.1016/j.exger.2005.01.012 (Pubitemid 40488203)
11. Dinarello C. A., Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process. The American Journal of Clinical Nutrition 2006 83 2 447s 455s 2-s2.0-33644854500 (Pubitemid 44713217)
12. Bartocci A., Papademetriou V., Schlick E., Nisula B. C., Chirigos M. A., Effect of crude and purified human chorionic gonadotropin on murine delayed-type hypersensitivity: a role for prostaglandins. Cellular Immunology 1982 71 2 326 333 2-s2.0-0019959462 (Pubitemid 12036916)
13. Meydani S. N., Meydani M., Verdon C. P., Shapiro A. A., Blumberg J. B., Hayes K. C., Vitamin E supplementation suppresses prostaglandin E1(2) synthesis and enhances the immune response of aged mice. Mechanisms of Ageing and Development 1986 34 2 191 201 (Pubitemid 16073269)
14. Meydani S. N., Barklund M. P., Liu S., Miller R. A., Cannon J. G., Morrow F. D., Rocklin R., Blumberg J. B., Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects. The American Journal of Clinical Nutrition 1990 52 3 557 563 2-s2.0-0025004702
15. Banfi G., Iorio E. L., Corsi M. M., Oxidative stress, free radicals and bone remodeling. Clinical Chemistry and Laboratory Medicine 2008 46 11 1550 1555 2-s2.0-56549089663 10.1515/CCLM.2008.302
16. Hayek M. G., Meydani S. N., Blumberg J. B., Age differences in eicosanoid production of mouse splenocytes: effects on mitogen-induced T-cell proliferation. Journals of Gerontology 1994 49 5 B197 B207 2-s2.0-0027989633 (Pubitemid 24282295)
17. Hayek M. G., Mura C., Wu D., Beharka A. A., Han S. N., Eric Paulson K., Hwang D., Meydani S. N., Enhanced expression of inducible cyclooxygenase with age in murine macrophages. Journal of Immunology 1997 159 5 2445 2451 2-s2.0-0031227764 (Pubitemid 127681039)
18. Wu D., Beharka A. A., Han S. N., Paulson K. E., Hwang D., Meydani S. N., Mura C., Age-associated increase in PGE2 synthesis and COX activity in murine macrophages is reversed by vitamin E. American Journal of Physiology-Cell Physiology 1998 275 3 C661 C668 2-s2.0-0031669304
19. Nathan C. F., Secretory products of macrophages. The Journal of Clinical Investigation 1987 79 2 319 326 2-s2.0-0023147156 (Pubitemid 17009661)
20. Mundy G. R., Cytokines and growth factors in the regulation of bone remodeling. Journal of Bone and Mineral Research 1993 8 supplement 2 S505 S510 2-s2.0-0027717065 (Pubitemid 24015239)
21. Harman D., Aging and oxidative stress. The Journal of the International Federation of Clinical Chemistry 1998 10 1 24 27 2-s2.0-0032013592
22. Garrett I. R., Boyce B. F., Oreffo R. O. C., Bonewald L., Poser J., Mundy G. R., Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. The Journal of Clinical Investigation 1990 85 3 632 639 2-s2.0-0025236484 (Pubitemid 20087462)
23. van't Hof R. J., Ralston S. H., Nitric oxide and bone. Immunology 2001 103 3 255 261 2-s2.0-0034931341 10.1046/j.1365-2567.2001.01261.x (Pubitemid 32626174)
24. Gokturk E., Turgut A., Baycu C., Gunal I., Seber S., Gulbas Z., Oxygen-free radicals impair fracture healing in rats. Acta Orthopaedica Scandinavica 1995 66 5 473 475 2-s2.0-0028825516
25. Basu S., Michaëlsson K., Olofsson H., Johansson S., Melhus H., Association between oxidative stress and bone mineral density. Biochemical and Biophysical Research Communications 2001 288 1 275 279 2-s2.0-0035914140 10.1006/bbrc.2001.5747 (Pubitemid 32999758)
26. Lean J. M., Davies J. T., Fuller K., Jagger C. J., Kirstein B., Partington G. A., Urry Z. L., Chambers T. J., A crucial role for thiol antioxidants in estrogen-deficiency bone loss. The Journal of Clinical Investigation 2003 112 6 915 923 2-s2.0-0142186681 10.1172/JCI200318859 (Pubitemid 38063749)
27. Muthusami S., Ramachandran I., Muthusamy B., Vasudevan G., Prabhu V., Subramaniam V., Jagadeesan A., Narasimhan S., Ovariectomy induces oxidative stress and impairs bone antioxidant system in adult rats. Clinica Chimica Acta 2005 360 1-2 81 86 2-s2.0-24044460427 10.1016/j.cccn.2005.04.014 (Pubitemid 41225396)
28. Crary E. J., McCarty M. F., Potential clinical applications for high-dose nutritional antioxidants. Medical Hypotheses 1984 13 1 77 98 2-s2.0-0021359702 (Pubitemid 14171029)
29. Azzi A., Breyer I., Feher M., Pastori M., Ricciarelli R., Spycher S., Staffieri M., Stocker A., Zimmer S., Zingg J.-M., Specific cellular responses to tocopherol. Journal of Nutrition 2000 130 7 1649 1652 2-s2.0-17744405988
30. Wang Y., Huang D. S., Liang B., Watson R. R., Nutritional status and immune responses in mice with murine AIDS are normalized by vitamin E supplementation. Journal of Nutrition 1994 124 10 2024 2032 2-s2.0-0028097387 (Pubitemid 24334638)
31. van Tits L. J., Demacker P. N., de Graaf J., Hak-Lemmers H. L., Stalenhoef A. F., Tocopherol supplementation decreases production of superoxide and cytokines by leukocytes ex vivo in both normolipidemic and hypertriglyceridemic individuals. The American Journal of Clinical Nutrition 2000 71 2 458 464 2-s2.0-0033979964 (Pubitemid 30061223)
32. Jialal I., Devaraj S., Kaul N., The effect of Tocopherol on monocyte proatherogenic activity. Journal of Nutrition 2001 131 2 389s 394s 2-s2.0-0035150318 (Pubitemid 32115387)
33. Wu D. Y., Hayek M. G., Meydani S. N., Vitamin E and macrophage cyclooxygenase regulation in the aged. Journal of Nutrition 2001 131 2 382S 288S 2-s2.0-0035256492
34. Asehnoune K., Strassheim D., Mitra S., Kim J. Y., Abraham E., Involvement of reactive oxygen species in toll-like receptor 4-dependent activation of NF- B. Journal of Immunology 2004 172 4 2522 2529 2-s2.0-0842321777 (Pubitemid 38182403)
35. Manolagas S. C., Jilka R. L., Mechanisms of disease: bone marrow, cytokines, and bone remodeling-emerging insights into the pathophysiology of osteoporosis. The New England Journal of Medicine 1995 332 5 305 311 2-s2.0-0028925088 10.1056/NEJM199502023320506
36. Ricciarelli R., Zingg J.-M., Azzi A., Vitamin E: protective role of a Janus molecule. The FASEB Journal 2001 15 13 2314 2325 2-s2.0-0035159165 10.1096/fj.01-0258rev (Pubitemid 33063160)
37. Xu H., Watkins B. A., Seifert M. F., Vitamin E stimulates trabecular bone formation and alters epiphyseal cartilage morphometry. Calcified Tissue International 1995 57 4 293 300 2-s2.0-0029079851 10.1007/BF00298885
38. Durak K., Bilgen Ö. F., Kaleli T., Tuncel P., Özbek R., Turan K., Antioxidant effect of tocopherol on fracture haematoma in rabbits. Journal of International Medical Research 1996 24 5 419 424 2-s2.0-0029830401 (Pubitemid 26343448)
39. Shuid A. N., Mohamad S., Muhammad N., Afian Mokhtar S., Muhammad N., Nirwana Soelaiman I., Bone oxidative changes during early fracture healing of postmenopausal osteoporosis rat model. Asian Journal of Animal and Veterinary Advances 2011 6 12 1193 1203
40. Shuid A. N., Mohamad S., Muhammad N., Fadzilah F. M., Mokhtar S. A., Mohamed N., Soelaiman I. N., Effects of tocopherol on the early phase of osteoporotic fracture healing. Journal of Orthopaedic Research 2011 29 11 1732 1738 2-s2.0-80053193162 10.1002/jor.21452
41. Mohamad S., Shuid A., Mohamed N., Fadzilah F., Mokhtar S., Abdullah S., The effects of alpha-tocopherol supplementation on fracture healing in a postmenopausal osteoporotic rat model. Clinics 2012 67 9 1077 1085
42. Turk C. Y., Halici M., Guney A., Akgun H., Sahin V., Muhtaroglu S., Promotion of fracture healing by vitamin E in rats. Journal of International Medical Research 2004 32 5 507 512 2-s2.0-4544353378 (Pubitemid 39255595)
43. Melhus H., Michaëlsson K., Holmberg L., Wolk A., Ljunghall S., Smoking, antioxidant vitamins, and the risk of hip fracture. Journal of Bone and Mineral Research 1999 14 1 129 135 2-s2.0-0345390062 10.1359/jbmr.1999.14.1.129 (Pubitemid 29021613)
44. Hamidi M. S., Corey P. N., Cheung A. M., Effects of vitamin E on bone turnover markers among US postmenopausal women. Journal of Bone and Mineral Research 2012 27 6 1368 1380
45. Arjmandi B. H., Juma S., Beharka A., Bapna M. S., Akhter M., Meydani S. N., Vitamin E improves bone quality in the aged but not in young adult male mice. The Journal of Nutritional Biochemistry 2002 13 9 543 549 2-s2.0-0036754813 10.1016/S0955-2863(02)00199-7 (Pubitemid 35286674)
46. Chai S. C., Wei C.-I., Brummel-Smith K., Arjmandi B. H., The role of vitamin E in reversing bone loss. Aging 2008 20 6 521 527 2-s2.0-60749114464
47. Smith B. J., Lucas E. A., Turner R. T., Evans G. L., Lerner M. R., Brackett D. J., Stoecker B. J., Arjmandi B. H., Vitamin E provides protection for bone in mature hindlimb unloaded male rats. Calcified Tissue International 2005 76 4 272 279 2-s2.0-22244439823 10.1007/s00223-004-0269-8 (Pubitemid 40991398)
48. Norazlina M., Ima-Nirwana S., Gapor M. T., Khalid B. A. K., Palm vitamin E is comparable to tocopherol in maintaining bone mineral density in ovariectomised female rats. Experimental and Clinical Endocrinology and Diabetes 2000 108 4 305 310 2-s2.0-0033924636 10.1055/s-2000-7758 (Pubitemid 30458603)
49. Arjmandi B. H., Getlinger M. J., Goyal N. V., Alekel L., Hasler C. M., Juma S., Drum M. L., Hollis B. W., Kukreja S. C., Role of soy protein with normal or reduced isoflavone content in reversing bone loss induced by ovarian hormone deficiency in rats. The American Journal of Clinical Nutrition 1998 68 supplement 6 1358S 1363S 2-s2.0-0031770982 (Pubitemid 28550912)
50. Bieri J. G., Tolliver T. J., Catignani G. L., Simultaneous determination of tocopherol and retinol in plasma or red cells by high pressure liquid chromatography. The American Journal of Clinical Nutrition 1979 32 10 2143 2149 2-s2.0-0018677726 (Pubitemid 10244809)
51. Akhter M. P., Iwaniec U. T., Haynatzki G. R., Fung Y. K., Cullen D. M., Recker R. R., Effects of nicotine on bone mass and strength in aged female rats. Journal of Orthopaedic Research 2003 21 1 14 19 2-s2.0-0346668304 10.1016/S0736-0266(02)00107-9 (Pubitemid 36163322)
52. Wasnich R. D., Ross P. D., Heilbrun L. K., Vogel J. M., Prediction of postmenopausal fracture risk with use of bone mineral measurements. The American Journal of Obstetrics and Gynecology 1985 153 7 745 751 2-s2.0-0022374775 (Pubitemid 16205569)
53. Kanis J. A., Osteoporosis III: diagnosis of osteoporosis and assessment of fracture risk. The Lancet 2002 359 9321 1929 1936 2-s2.0-0036606093 10.1016/S0140-6736(02)08761-5 (Pubitemid 34615775)
54. Taaffe D. R., Lang T. F., Harris T. B., Poor correlation of mid-femoral measurements by CT and hip measurements by DXA in the elderly. Aging 2003 15 2 131 135 2-s2.0-0038383272 (Pubitemid 36889498)
55. Wardlaw G. M., Putting osteoporosis in perspective. Journal of the American Dietetic Association 1993 93 9 1000 1006 2-s2.0-0027171682 10.1016/0002-8223(93)92038-Y (Pubitemid 23267862)
56. Delmas P. D., Treatment of postmenopausal osteoporosis. The Lancet 2002 359 9322 2018 2026 2-s2.0-0037042498 10.1016/S0140-6736(02)08827-X (Pubitemid 34663722)
57. Arjmandi B. H., Akhter M., Chakkalakal D., Effects of isoflavones, vitamin E, and their combination on bone in an aged rat model of osteopenia. Journal of Bone and Mineral Research 2001 16 supplement 1 s533
58. Shuid A. N., Mehat Z., Mohamed N., Muhammad N., Soelaiman I. N., Vitamin E exhibits bone anabolic actions in normal male rats. Journal of Bone and Mineral Metabolism 2010 28 2 149 156 2-s2.0-77952478816 10.1007/s00774-009-0122- 2
59. Traber M. G., Sies H., Vitamin E in humans: demand and delivery. Annual Review of Nutrition 1996 16 321 347 2-s2.0-0029798873 (Pubitemid 26286857)
60. Schultz M., Leist M., Petrzika M., Gassmann B., Brigelius-Flohe R., Novel urinary metabolite of tocopherol, 2,5,7,8-tetramethyl-2(2′- carboxyethyl)-6-hydroxychroman, as an indicator of an adequate vitamin E supply? The American Journal of Clinical Nutrition 1995 62 6 S1527 S1534 2-s2.0-0028858639
61. Jialal I., Fuller C. J., Huet B. A., The effect of tocopherol supplementation on LDL oxidation. A dose-response study. Arteriosclerosis, Thrombosis, and Vascular Biology 1995 15 2 190 198 2-s2.0-0028986372
62. Blatt D. H., Leonard S. W., Traber M. G., Vitamin E kinetics and the function of tocopherol regulatory proteins. Nutrition 2001 17 10 799 805 2-s2.0-0034773330 10.1016/S0899-9007(01)00637-2 (Pubitemid 33001643)
63. Fujita K., Iwasaki M., Ochi H., Fukuda T., Ma C., Miyamoto T., Takitani K., Negishi-Koga T., Sunamura S., Kodama T., Takayanagi H., Tamai H., Kato S., Arai H., Shinomiya K., Itoh H., Okawa A., Takeda S., Vitamin E decreases bone mass by stimulating osteoclast fusion. Nature Medicine 2012 18 4 589 594 2-s2.0-84859597301 10.1038/nm.2659
64. Hermizi H., Faizah O., Ima-Nirwana S., Ahmad Nazrun S., Norazlina M., Beneficial effects of tocotrienol and tocopherol on bone histomorphometric parameters in Sprague-Dawley male rats after nicotine cessation. Calcified Tissue International 2009 84 1 65 74 2-s2.0-58149314166 10.1007/s00223-008-9190- x
65. Ahmad N. S., Khalid B. A. K., Luke D. A., Nirwana S. I., Tocotrienol offers better protection than tocopherol from free radical-induced damage of rat bone. Clinical and Experimental Pharmacology and Physiology 2005 32 9 761 770 2-s2.0-26944436739 10.1111/j.1440-1681.2005.04264.x (Pubitemid 41603156)
66. Mehat M. Z., Shuid A. N., Mohamed N., Muhammad N., Soelaiman I. N., Beneficial effects of vitamin E isomer supplementation on static and dynamic bone histomorphometry parameters in normal male rats. Journal of Bone and Mineral Metabolism 2010 28 5 503 509 2-s2.0-77956900893 10.1007/s00774-010-0159- 2
67. Meydani M., Vitamin E and atherosclerosis: beyond prevention of LDL oxidation. Journal of Nutrition 2001 131 2 366S 368S 2-s2.0-0035152976 (Pubitemid 32115382)
68. Chai S. C., Arjmandi B. H., Vitamin E dose-dependently reduces aortic fatty lesion formation in orchidectomized aged rats. Aging 2011 23 1 11 16 2-s2.0-79956329684 10.3275/6762
69. Dutta A., Dutta S. K., Vitamin E and its role in the prevention of atherosclerosis and carcinogenesis: a review. Journal of the American College of Nutrition 2003 22 4 258 268 2-s2.0-0041767335 (Pubitemid 36927760)
70. Wu D., Hayek M. G., Meydani S., Vitamin E and macrophage cyclooxygenase regulation in the aged. Journal of Nutrition 2001 131 2 382S 388S 2-s2.0-0035256492
71. Beharka A. A., Wu D., Han S. N., Meydani S. N., Macrophage prostaglandin production contributes to the age-associated decrease in T cell function which is reversed by the dietary antioxidant vitamin E. Mechanisms of Ageing and Development 1997 93 1-3 59 77 2-s2.0-0030887804 10.1016/S0047-6374(96)01819-2 (Pubitemid 27138329)
72. Wu D. Y., Meydani M., Beharka A. A., Serafini M., Martin K. R., Meydani S. N., In vitro supplementation with different tocopherol homologues can affect the function of immune cells in old mice. Free Radical Biology and Medicine 2000 28 4 643 651 2-s2.0-0034652610 10.1016/S0891-5849(99)00276-2 (Pubitemid 30136046)
73. Pfeilschifter J., Köditz R., Pfohl M., Schatz H., Changes in proinflammatory cytokine activity after menopause. Endocrine Reviews 2002 23 1 90 119 2-s2.0-0036188807 10.1210/er.23.1.90 (Pubitemid 34185307)
74. Beharka A. A., Han S. N., Adolfsson O., Wu D., Smith D., Lipman R., Cao G., Meydani M., Long-term dietary antioxidant supplementation reduces production of selected inflammatory mediators by murine macrophages. Nutrition Research 2000 20 2 281 296 2-s2.0-0034141191 10.1016/S0271-5317(99)00160-8 (Pubitemid 30084531)