EZH2-shRNA-mediated upregulation of p21waf1/cip1 and its transcriptional enhancers with concomitant downmodulation of mutant p53 in pancreatic ductal adenocarcinoma

Surgery (United States)

Volumn 154, Issue 4, 2013, Pages 739-747

  Batchu, Ramesh B ^a,b   Qazi, Aamer M ^a,b   Gruzdyn, Oksana V ^a,b   Semaan, Assaad ^a   Seward, Shelly M ^a   Chamala, Sreedhar ^a   Dhulipala, Vasu B ^a,b   Bouwman, David L ^a   Weaver, Donald W ^a   Gruber, Scott A ^a,b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; ENHANCER OF ZESTE HOMOLOGUE 2 PROTEIN; PROTEIN P21; PROTEIN P53; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL INVASION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR UPREGULATION; TUMOR XENOGRAFT; WESTERN BLOTTING;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; ENHANCER ELEMENTS, GENETIC; GENES, P53; HUMANS; MICE; PANCREATIC NEOPLASMS; POLYCOMB REPRESSIVE COMPLEX 2; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 84884834858     PISSN: 00396060     EISSN: 15327361     Source Type: Journal    
DOI: 10.1016/j.surg.2013.06.041     Document Type: Article

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