메뉴 건너뛰기




Volumn 34, Issue 37, 2013, Pages 9381-9392

RhBMP-2-loaded calcium silicate/calcium phosphate cement scaffold with hierarchically porous structure for enhanced bone tissue regeneration

Author keywords

Bone regeneration; Calcium silicate calcium phosphate cement; Hierarchical porosity; RhBMP 2

Indexed keywords

BONE REGENERATION; BONE TISSUE REGENERATION; CALCIUM PHOSPHATE CEMENT; ECTOPIC BONE FORMATIONS; HIERARCHICAL POROSITY; OSTEOGENIC DIFFERENTIATION; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2 (RHBMP-2); RHBMP-2;

EID: 84884816926     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.08.059     Document Type: Article
Times cited : (138)

References (35)
  • 1
    • 80051550264 scopus 로고    scopus 로고
    • The performance of rhBMP-2 loaded TCP/HAP porous ceramics with a polyelectrolyte multilayer film coating
    • Crouzier T., Sailhan F., Becquart P., Guillot R., Logeart-Avramoglou D., Picart C. The performance of rhBMP-2 loaded TCP/HAP porous ceramics with a polyelectrolyte multilayer film coating. Biomaterials 2011, 32:7543-7554.
    • (2011) Biomaterials , vol.32 , pp. 7543-7554
    • Crouzier, T.1    Sailhan, F.2    Becquart, P.3    Guillot, R.4    Logeart-Avramoglou, D.5    Picart, C.6
  • 2
    • 79960581511 scopus 로고    scopus 로고
    • Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects
    • Kolambkar Y.M., Boerckel J.D., Dupont K.M., Bajin M., Huebsch N., Mooney D.J., et al. Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects. Bone 2011, 49:485-492.
    • (2011) Bone , vol.49 , pp. 485-492
    • Kolambkar, Y.M.1    Boerckel, J.D.2    Dupont, K.M.3    Bajin, M.4    Huebsch, N.5    Mooney, D.J.6
  • 3
    • 79959824527 scopus 로고    scopus 로고
    • Direct deposited porous scaffolds of calcium phosphate cement with alginate for drug delivery and bone tissue engineering
    • Lee G.S., Park J.H., Shin U.S., Kim H.W. Direct deposited porous scaffolds of calcium phosphate cement with alginate for drug delivery and bone tissue engineering. Acta Biomaterialia 2011, 7:3178-3186.
    • (2011) Acta Biomaterialia , vol.7 , pp. 3178-3186
    • Lee, G.S.1    Park, J.H.2    Shin, U.S.3    Kim, H.W.4
  • 4
    • 34748892318 scopus 로고    scopus 로고
    • Reactivity of calcium phosphate cements
    • Bohner M. Reactivity of calcium phosphate cements. JMater Chem 2007, 17:3980-3986.
    • (2007) JMater Chem , vol.17 , pp. 3980-3986
    • Bohner, M.1
  • 5
    • 77649273662 scopus 로고    scopus 로고
    • Human umbilical cord stem cell encapsulation in calcium phosphate scaffolds for bone engineering
    • Zhao L., Weir M.D., Xu H.H.K. Human umbilical cord stem cell encapsulation in calcium phosphate scaffolds for bone engineering. Biomaterials 2010, 31:3848-3857.
    • (2010) Biomaterials , vol.31 , pp. 3848-3857
    • Zhao, L.1    Weir, M.D.2    Xu, H.H.K.3
  • 7
    • 64249096970 scopus 로고    scopus 로고
    • Influences of ionic dissolution products of dicalcium silicate coating on osteoblastic proliferation, differentiation and gene expression
    • Sun J.Y., Wei L., Liu X.Y., Li J.Y., Li B., Wang G.C., et al. Influences of ionic dissolution products of dicalcium silicate coating on osteoblastic proliferation, differentiation and gene expression. Acta Biomaterialia 2009, 5:1284-1293.
    • (2009) Acta Biomaterialia , vol.5 , pp. 1284-1293
    • Sun, J.Y.1    Wei, L.2    Liu, X.Y.3    Li, J.Y.4    Li, B.5    Wang, G.C.6
  • 9
    • 77951954506 scopus 로고    scopus 로고
    • Invitro osteoblast-like and endothelial cells' response to calcium silicate/calcium phosphate cement
    • Zhao Q.H., Qian J.C., Zhou H.J., Yuan Y., Liu C.S. Invitro osteoblast-like and endothelial cells' response to calcium silicate/calcium phosphate cement. Biomed Mater 2010, 5(3):035004.
    • (2010) Biomed Mater , vol.5 , Issue.3 , pp. 035004
    • Zhao, Q.H.1    Qian, J.C.2    Zhou, H.J.3    Yuan, Y.4    Liu, C.S.5
  • 10
    • 34548432635 scopus 로고    scopus 로고
    • Development of calcium silicate/calcium phosphate cement for bone regeneration
    • Guo H., Wei J., Yuan Y., Liu C.S. Development of calcium silicate/calcium phosphate cement for bone regeneration. Biomed Mater 2007, 2(3):S153-S159.
    • (2007) Biomed Mater , vol.2 , Issue.3
    • Guo, H.1    Wei, J.2    Yuan, Y.3    Liu, C.S.4
  • 11
    • 33748904647 scopus 로고    scopus 로고
    • The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity
    • Woodard J.R., Hilldore A.J., Lan Levengood S.K., Wagoner J.A.J. The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity. Biomaterials 2007, 28:45-54.
    • (2007) Biomaterials , vol.28 , pp. 45-54
    • Woodard, J.R.1    Hilldore, A.J.2    Lan Levengood, S.K.3    Wagoner, J.A.J.4
  • 12
    • 73549098444 scopus 로고    scopus 로고
    • The pore size of polycaprolactone scaffolds has limited influence on bone regeneration in an invivo model
    • Mantila R.S.M., Kemppainen J.M., Moffitt E.N., Krebsbach P.H., Hollister S.J. The pore size of polycaprolactone scaffolds has limited influence on bone regeneration in an invivo model. JBiomed Mater Res A 2009, 92:359-368.
    • (2009) JBiomed Mater Res A , vol.92 , pp. 359-368
    • Mantila, R.S.M.1    Kemppainen, J.M.2    Moffitt, E.N.3    Krebsbach, P.H.4    Hollister, S.J.5
  • 13
    • 21844443709 scopus 로고    scopus 로고
    • Microporosity enhances bioactivity of synthetic bone graft substitutes
    • Hing K.A., Annaz B., Saeed S., Revell P.A., Buckland T. Microporosity enhances bioactivity of synthetic bone graft substitutes. JMater Sci Mater Med 2005, 16(5):467-475.
    • (2005) JMater Sci Mater Med , vol.16 , Issue.5 , pp. 467-475
    • Hing, K.A.1    Annaz, B.2    Saeed, S.3    Revell, P.A.4    Buckland, T.5
  • 14
    • 77956644933 scopus 로고    scopus 로고
    • The effect of rhBMP-2 on micro- and macroscale osteointegration of biphasic calcium phosphate scaffolds with multiscale porosity
    • Lan Levengood S.K., Polak S.J., Poellmann M.J., Hoelzle D.J., Maki A.J., Clark S.G., et al. The effect of rhBMP-2 on micro- and macroscale osteointegration of biphasic calcium phosphate scaffolds with multiscale porosity. Acta Biomaterialia 2010, 6:3283-3291.
    • (2010) Acta Biomaterialia , vol.6 , pp. 3283-3291
    • Lan Levengood, S.K.1    Polak, S.J.2    Poellmann, M.J.3    Hoelzle, D.J.4    Maki, A.J.5    Clark, S.G.6
  • 15
    • 57349168055 scopus 로고    scopus 로고
    • Calcium phosphate-based osteoinductive materials
    • LeGeros R.Z. Calcium phosphate-based osteoinductive materials. Chem Rev 2008, 108:4742-4753.
    • (2008) Chem Rev , vol.108 , pp. 4742-4753
    • LeGeros, R.Z.1
  • 16
    • 77249089216 scopus 로고    scopus 로고
    • Multiscale osteointegration as a new paradigm for the design of calcium phosphate scaffolds for bone regeneration
    • Lan Levengood S.K., Polak S.J., Wagoner J.A.J. Multiscale osteointegration as a new paradigm for the design of calcium phosphate scaffolds for bone regeneration. Biomaterials 2010, 31:3552-3563.
    • (2010) Biomaterials , vol.31 , pp. 3552-3563
    • Lan Levengood, S.K.1    Polak, S.J.2    Wagoner, J.A.J.3
  • 17
    • 77949360930 scopus 로고    scopus 로고
    • Polysaccharide-blend multilayers containing hyaluronan and heparin as a delivery system for rhBMP-2
    • Crouzier T., Szarpak A., Boudou T., Auzély-Velty R., Picart C. Polysaccharide-blend multilayers containing hyaluronan and heparin as a delivery system for rhBMP-2. Small 2010, 6(5):651-662.
    • (2010) Small , vol.6 , Issue.5 , pp. 651-662
    • Crouzier, T.1    Szarpak, A.2    Boudou, T.3    Auzély-Velty, R.4    Picart, C.5
  • 18
  • 19
    • 57749185245 scopus 로고    scopus 로고
    • Directional rhBMP-2 for functionalization of titanium surfaces
    • Kashiwagi K., Tsuji T., Shiba K. Directional rhBMP-2 for functionalization of titanium surfaces. Biomaterials 2009, 30:1166-1175.
    • (2009) Biomaterials , vol.30 , pp. 1166-1175
    • Kashiwagi, K.1    Tsuji, T.2    Shiba, K.3
  • 20
    • 59849120814 scopus 로고    scopus 로고
    • The effect of an rhBMP-2 absorbable collagen sponge-targeted system on bone formation invivo
    • Visser R., Arrabal P.M., Becerra J., Rinas U., Cifuentes M. The effect of an rhBMP-2 absorbable collagen sponge-targeted system on bone formation invivo. Biomaterials 2009, 30(11):2032-2037.
    • (2009) Biomaterials , vol.30 , Issue.11 , pp. 2032-2037
    • Visser, R.1    Arrabal, P.M.2    Becerra, J.3    Rinas, U.4    Cifuentes, M.5
  • 21
    • 77954026484 scopus 로고    scopus 로고
    • Calcium phosphate cement with rhBMP-2-loaded gelatin microspheres enhances bone healing in osteoporosis
    • Li M., Liu X.Y., Liu X.D., Ge B.F. Calcium phosphate cement with rhBMP-2-loaded gelatin microspheres enhances bone healing in osteoporosis. Clin Orthop Relat Res 2010, 468:1978-1985.
    • (2010) Clin Orthop Relat Res , vol.468 , pp. 1978-1985
    • Li, M.1    Liu, X.Y.2    Liu, X.D.3    Ge, B.F.4
  • 22
    • 60649121935 scopus 로고    scopus 로고
    • Porous nano-HA/collagen/PLLA scaffold containing chitosan microspheres for controlled delivery of synthetic peptide derived from rhBMP-2
    • Niu X.F., Feng Q.L., Wang M.B., Guo X.D., Zheng Q.X. Porous nano-HA/collagen/PLLA scaffold containing chitosan microspheres for controlled delivery of synthetic peptide derived from rhBMP-2. JControlled Release 2009, 134:111-117.
    • (2009) JControlled Release , vol.134 , pp. 111-117
    • Niu, X.F.1    Feng, Q.L.2    Wang, M.B.3    Guo, X.D.4    Zheng, Q.X.5
  • 24
    • 70349871404 scopus 로고    scopus 로고
    • The effects of rhBMP-2 released from biodegradable polyurethane/microsphere composite scaffolds on new bone formation in rat femora
    • Li B., Toshitaka Y., Hafeman A.E., Nymanb J.S., Wenke J.C., Guelcher S.A. The effects of rhBMP-2 released from biodegradable polyurethane/microsphere composite scaffolds on new bone formation in rat femora. Biomaterials 2009, 30:6768-6779.
    • (2009) Biomaterials , vol.30 , pp. 6768-6779
    • Li, B.1    Toshitaka, Y.2    Hafeman, A.E.3    Nymanb, J.S.4    Wenke, J.C.5    Guelcher, S.A.6
  • 25
    • 80053595685 scopus 로고    scopus 로고
    • Spatial segregation of BMP/Smad signaling affects osteoblast differentiation in C2C12 cells
    • Heining E., Bhushan R., Paarmann P., Henis Y., Knaus P. Spatial segregation of BMP/Smad signaling affects osteoblast differentiation in C2C12 cells. PLOS One 2011, 10(6):25163.
    • (2011) PLOS One , vol.10 , Issue.6 , pp. 25163
    • Heining, E.1    Bhushan, R.2    Paarmann, P.3    Henis, Y.4    Knaus, P.5
  • 26
    • 58849161220 scopus 로고    scopus 로고
    • Enhanced bioactivity of bone morphogenetic protein-2 with low dose of 2-N,6-O-sulfated chitosan invitro and invivo
    • Zhou H., Qian J., Wang J., Yao W., Liu C., Chen J., et al. Enhanced bioactivity of bone morphogenetic protein-2 with low dose of 2-N,6-O-sulfated chitosan invitro and invivo. Biomaterials 2009, 30:1715-1724.
    • (2009) Biomaterials , vol.30 , pp. 1715-1724
    • Zhou, H.1    Qian, J.2    Wang, J.3    Yao, W.4    Liu, C.5    Chen, J.6
  • 29
    • 77956487717 scopus 로고    scopus 로고
    • Cryogenic prototyping of chitosan scaffolds with controlled micro and macro architecture and their effect on invivo neo-vascularization and cellular infiltration
    • Lim T.C., Chian K.S., Leong K.F. Cryogenic prototyping of chitosan scaffolds with controlled micro and macro architecture and their effect on invivo neo-vascularization and cellular infiltration. JBiomed Mater Res A 2010, 94A(4):1303-1311.
    • (2010) JBiomed Mater Res A , vol.94 A , Issue.4 , pp. 1303-1311
    • Lim, T.C.1    Chian, K.S.2    Leong, K.F.3
  • 30
    • 79952846016 scopus 로고    scopus 로고
    • Conformational analysis of aqueous rhBMP-2 using atomistic molecular dynamics simulations
    • Oliveira A.F., Gemming S., Seifert G. Conformational analysis of aqueous rhBMP-2 using atomistic molecular dynamics simulations. JPhys Chem B 2011, 115:1122-1130.
    • (2011) JPhys Chem B , vol.115 , pp. 1122-1130
    • Oliveira, A.F.1    Gemming, S.2    Seifert, G.3
  • 31
    • 71649086672 scopus 로고    scopus 로고
    • Adsorption and release of rhBMP-2 on nanocrystalline apatite-coated and uncoated hydroxyapatite/beta-tricalcium phosphate porous ceramics
    • Autefage H., Briand-Mesange F., Cazalbou S., Drouet C., Fourmy D., Goncalves S., et al. Adsorption and release of rhBMP-2 on nanocrystalline apatite-coated and uncoated hydroxyapatite/beta-tricalcium phosphate porous ceramics. JBiomed Mater Res B Appl Biomater 2009, 91:706-715.
    • (2009) JBiomed Mater Res B Appl Biomater , vol.91 , pp. 706-715
    • Autefage, H.1    Briand-Mesange, F.2    Cazalbou, S.3    Drouet, C.4    Fourmy, D.5    Goncalves, S.6
  • 32
    • 34547138268 scopus 로고    scopus 로고
    • Understanding adsorption-desorption dynamics of rhBMP-2 on hydroxyapatite (001) surface
    • Dong X., Wang Q., Wu T., Pan H. Understanding adsorption-desorption dynamics of rhBMP-2 on hydroxyapatite (001) surface. Biophys J 2007, 93:750-759.
    • (2007) Biophys J , vol.93 , pp. 750-759
    • Dong, X.1    Wang, Q.2    Wu, T.3    Pan, H.4
  • 33
    • 73749087158 scopus 로고    scopus 로고
    • Inhibition mechanism of lanthanum ion on the activity of horseradish peroxidase invitro
    • Guo S.F., Wang L.H., Lu A.H., Lu T.H., Ding X.L., Huang X.H. Inhibition mechanism of lanthanum ion on the activity of horseradish peroxidase invitro. Spectrochimica Acta Part A 2010, 75:936-940.
    • (2010) Spectrochimica Acta Part A , vol.75 , pp. 936-940
    • Guo, S.F.1    Wang, L.H.2    Lu, A.H.3    Lu, T.H.4    Ding, X.L.5    Huang, X.H.6
  • 34
    • 80052966691 scopus 로고    scopus 로고
    • Osteogenic evaluation of calcium/magnesium-doped mesoporous silica scaffold with incorporation of rhBMP-2 by synchrotron radiation-based μCT
    • Dai C.L., Guo H., Lu J.X., Shi J.L., Wei J., Liu C.S. Osteogenic evaluation of calcium/magnesium-doped mesoporous silica scaffold with incorporation of rhBMP-2 by synchrotron radiation-based μCT. Biomaterials 2011, 32(33):8506-8517.
    • (2011) Biomaterials , vol.32 , Issue.33 , pp. 8506-8517
    • Dai, C.L.1    Guo, H.2    Lu, J.X.3    Shi, J.L.4    Wei, J.5    Liu, C.S.6
  • 35
    • 0037039862 scopus 로고    scopus 로고
    • Third-generation biomedical materials
    • Hench L.L., Polak J.M. Third-generation biomedical materials. Science 2002, 295:1014-1017.
    • (2002) Science , vol.295 , pp. 1014-1017
    • Hench, L.L.1    Polak, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.