Self-crosslinked human serum albumin nanocarriers for systemic delivery of polymerized siRNA to tumors

Biomaterials

Volumn 34, Issue 37, 2013, Pages 9475-9485

  Son, Sohee ^a   Song, Seungyong ^a   Lee, So Jin ^a   Min, Solki ^a   Kim, Sun Ah ^a   Yhee, Ji Young ^a   Huh, Myung Sook ^a   Chan Kwon, Ick ^a,b   Jeong, Seo Young ^c   Byun, Youngro ^d   Kim, Sun Hwa ^a   Kim, Kwangmeyung ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea University   (South Korea)

^c Kyung Hee University   (South Korea)

^d Seoul National University   (South Korea)

Author keywords

Cancer therapy; Human serum albumin; Polymerized siRNA; Protein based carrier; RNAi

Indexed keywords

CANCER THERAPEUTICS; CANCER THERAPY; CHEMICAL CROSS-LINKING; HUMAN SERUM ALBUMINS; INTRAVENOUS INJECTIONS; POLYMERIZED SIRNA; RNAI; SYSTEMIC DELIVERIES;

BINDING ENERGY; CROSSLINKING; DISEASES; DYES; GENETIC ENGINEERING; LIPOSOMES; MOLECULES; POLYMERS; PROTEINS; TUMORS;

GENE THERAPY;

HUMAN SERUM ALBUMIN; LIPOFECTAMINE; NANOCARRIER; RED FLUORESCENT PROTEIN; SMALL INTERFERING RNA; THIOL; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER GENE THERAPY; CANCER INHIBITION; CONTROLLED STUDY; CROSS LINKING; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG STABILITY; GENE DELIVERY SYSTEM; GENE SILENCING; GENE TARGETING; IN VITRO STUDY; INTERNALIZATION; MALE; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROSTATE CANCER; SELF CROSSLINKING; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT;

MUS;

CANCER THERAPY; HUMAN SERUM ALBUMIN; POLYMERIZED SIRNA; PROTEIN BASED CARRIER; RNAI;

ANIMALS; CELL LINE, TUMOR; DRUG CARRIERS; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MODELS, MOLECULAR; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; POLYMERIZATION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SERUM ALBUMIN; SULFHYDRYL COMPOUNDS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84884814016     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.08.085     Document Type: Article

References (27)

1. Pecot C.V., Calin G.A., Coleman R.L., Lopez-Berestein G., Sood A.K. RNA interference in the clinic: challenges and future directions. Nat Rev Cancer 2011, 11:59-67.
2. Beloor J., Choi C.S., Nam H.Y., Park M., Kim S.H., Jackson A., et al. Arginine-engrafted biodegradable polymer for the systemic delivery of therapeutic siRNA. Biomaterials 2012, 33:1640-1650.
3. Ganesh S., Iyer A.K., Morrissey D.V., Amiji M.M. Hyaluronic acid based self-assembling nanosystems for CD44 target mediated siRNA delivery to solid tumors. Biomaterials 2013, 34:3489-3502.
4. Wang J., Lu Z., Wientjes M.G., Au J.L. Delivery of siRNA therapeutics: barriers and carriers. AAPS J 2010, 12:492-503.
5. Agarwal A., Unfer R., Mallapragada S.K. Novel cationic pentablock copolymers as non-viral vectors for gene therapy. JControl Release 2005, 103:245-258.
6. Tamura A., Yui N. Cellular internalization and gene silencing of siRNA polyplexes by cytocleavable cationic polyrotaxanes with tailored rigid backbones. Biomaterials 2013, 34:2480-2491.
7. Mok H., Lee S.H., Park J.W., Park T.G. Multimeric small interfering ribonucleic acid for highly efficient sequence-specific gene silencing. Nat Mater 2010, 9:272-278.
8. Lee J.B., Hong J., Bonner D.K., Poon Z., Hammond P.T. Self-assembled RNA interference microsponges for efficient siRNA delivery. Nat Mater 2012, 11:316-322.
9. Huh M.S., Lee S.Y., Park S., Lee S., Chung H., Choi Y., et al. Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice. JControl Release 2010, 144:134-143.
10. Lee S.Y., Huh M.S., Lee S., Lee S.J., Chung H., Park J.H., et al. Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing. JControl Release 2010, 141:339-346.
11. Kratz F. Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. JControl Release 2008, 132:171-183.
12. Cheng W., Yang C., Hedrick J.L., Williams D.F., Yang Y.Y., Ashton-Rickardt P.G. Delivery of a granzyme B inhibitor gene using carbamate-mannose modified PEI protects against cytotoxic lymphocyte killing. Biomaterials 2013, 34:3697-3705.
13. Kuijpers A.J., van Wachem P.B., van Luyn M.J., Brouwer L.A., Engbers G.H., Krijgsveld J., et al. Invitro and invivo evaluation of gelatin-chondroitin sulphate hydrogels for controlled release of antibacterial proteins. Biomaterials 2000, 21:1763-1772.
14. Ishikawa H., Nakamura Y., Jo J., Tabata Y. Gelatin nanospheres incorporating siRNA for controlled intracellular release. Biomaterials 2012, 33:9097-9104.
15. Stehle G., Sinn H., Wunder A., Schrenk H.H., Stewart J.C., Hartung G., et al. Plasma protein (albumin) catabolism by the tumor itself - implications for tumor metabolism and the genesis of cachexia. Crit Rev Oncol Hematol 1997, 26:77-100.
16. Landen C.N., Chavez-Reyes A., Bucana C., Schmandt R., Deavers M.T., Lopez-Berestein G., et al. Therapeutic EphA2 gene targeting invivo using neutral liposomal small interfering RNA delivery. Cancer Res 2005, 65:6910-6918.
17. Jafari M., Chen P. Peptide mediated siRNA delivery. Curr Top Med Chem 2009, 9:1088-1097.
18. Elzoghby A.O., El-Fotoh W.S., Elgindy N.A. Casein-based formulations as promising controlled release drug delivery systems. JControl Release 2011, 153:206-216.
19. Boe S.L., Longva A.S., Hovig E. Cyclodextrin-containing polymer delivery system for light-directed siRNA gene silencing. Oligonucleotides 2010, 20:175-182.
20. Arnedo A., Irache J.M., Merodio M., Espuelas Millan M.S. Albumin nanoparticles improved the stability, nuclear accumulation and anticytomegaloviral activity of a phosphodiester oligonucleotide. JControl Release 2004, 94:217-227.
21. Kummitha C.M., Malamas A.S., Lu Z.R. Albumin pre-coating enhances intracellular siRNA delivery of multifunctional amphiphile/siRNA nanoparticles. Int J Nanomed 2012, 7:5205-5214.
22. Mo Y., Barnett M.E., Takemoto D., Davidson H., Kompella U.B. Human serum albumin nanoparticles for efficient delivery of Cu, Zn superoxide dismutase gene. Mol Vis 2007, 13:746-757.
23. Lee S.J., Huh M.S., Lee S.Y., Min S., Lee S., Koo H., et al. Tumor-homing poly-siRNA/glycol chitosan self-cross-linked nanoparticles for systemic siRNA delivery in cancer treatment. Angew Chem Int Ed Engl 2012, 51:7203-7207.
24. Perret F., Lazar A.N., Coleman A.W. Biochemistry of the para-sulfonato-calix[n]arenes. Chem Commun 2006, 2425-2438.
25. Bell G.I., Dembo M., Bongrand P. Cell adhesion. Competition between nonspecific repulsion and specific bonding. Biophys J 1984, 45:1051-1064.
26. Mailander V., Lorenz M.R., Holzapfel V., Musyanovych A., Fuchs K., Wiesneth M., et al. Carboxylated superparamagnetic iron oxide particles label cells intracellularly without transfection agents. Mol Imaging Biol 2008, 10:138-146.
27. Petersen I. Antiangiogenesis, anti-VEGF(R) and outlook. Recent Results Cancer Res 2007, 176:189-199.