Association of interleukin-12 polymorphisms and serum IL-12p40 levels with osteosarcoma risk

DNA and Cell Biology

Volumn 32, Issue 10, 2013, Pages 605-610

  Wang, Junli ^a   Nong, Legen ^a   Wei, Yesheng ^a   Qin, Shanyu ^b   Zhou, You ^c   Tang, Yujin ^a  

^a Hospital of Youjiang   (China)

^b FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

^c MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; INTERLEUKIN 12P40;

ADULT; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; CHINESE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; METASTASIS; OSTEOSARCOMA; POLYMERASE CHAIN REACTION; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR LOCALIZATION;

ASIAN CONTINENTAL ANCESTRY GROUP; DEMOGRAPHY; ETHNIC GROUPS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERLEUKIN-12 SUBUNIT P40; MALE; OSTEOSARCOMA; POLYMORPHISM, GENETIC; YOUNG ADULT;

EID: 84884795046     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2013.2098     Document Type: Article

References (34)

1. Becskei, A., and Grusby, M.J. (.2007). Contribution of IL-12R mediated feedback loop to Th1 cell differentiation. FEBS Lett 581, 5199-5206
2. Cavallo, F., Quaglino, E., Cifaldi, L., Di Carlo, E., Andre, A., Bernabei, P., et al. (.2001). Interleukin 12-activated lymphocytes influence tumor genetic programs. Cancer Res 61, 3518-3523
3. Chen, X., Han, S., Wang, S., Zhou, X., Zhang, M., Dong, J., et al. (.2009). Interactions of IL-12A and IL-12B polymorphisms on the risk of cervical cancer in Chinese women. Clin Cancer Res 15, 400-405
4. Del Vecchio, M., Bajetta, E., Canova, S., Lotze, M.T., Wesa, A., Parmiani, G., et al. (.2007). Interleukin-12: Biological properties and clinical application. Clin Cancer Res 13, 4677-4685
5. Dorfman, H.D., and Czerniak, B. (.1995). Bone cancers. Cancer 75, 203-10
6. Duan, X., Jia, S.F., Koshkina, N., and Kleinerman, E.S. 2006 Intranasal interleukin-12 gene therapy enhanced the activity of ifosfamide against osteosarcoma lung metastases. Cancer 106, 1382-1388
7. Foukas, L.C., Panayotou, G., and Shepherd, P.R. (.2004). Direct interaction of major histocompatibility complex class IIderived peptides with class Ia phosphoinositide 3-kinase results in dose-dependent stimulatory effects. J Biol Chem 279, 7505-7511
8. Gumperz, J.E. (.2004). CD1d-restricted ''NKT'' cells and myeloid IL-12 production: An immunological crossroads leading to promotion or suppression of effective anti-tumor immune responses? J Leukoc Biol 76, 307-313
9. Howell, W.M., and Rose-Zerilli, M.J. (.2007). Cytokine gene polymorphisms, cancer susceptibility, and prognosis. J Nutr 137, 194S-9S
10. Ikeda, H., Old, L.J., and Schreiber, R.D. (.2002). The roles of IFN gamma in protection against tumor development and cancer immunoediting. Cytokine Growth Factor Rev 13, 95-109
11. Jaiswal, P.K., Singh, V., Srivastava, P., and Mittal, R.D. 2013 Association of IL-12, IL-18 variants and serum IL-18 with bladder cancer susceptibility in North Indian population. Gene 519, 128-134
12. John, S.W., Weitzner, G., Rozen, R., and Scriver, C.R. (.1991). A rapid procedure for extracting genomic DNA from leukocytes. Nucleic Acids Res 19, 408
13. Jones, L.L., Chaturvedi, V., Uyttenhove, C., Van Snick, J., and Vignali, D.A. (.2012). Distinct subunit pairing criteria within the heterodimeric IL-12 cytokine family. Mol Immunol 51, 234-244
14. Kaarvatn, M.H., Vrbanec, J., Kulic, A., Knezevic, J., Petricevic, B., Balen, S., et al. (.2012). Single nucleotide polymorphism in the interleukin 12B gene is associated with risk for breast cancer development. Scand J Immunol 76, 329-335
15. Lin, W.W., and Karin, M. (.2007). A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117, 1175-1183
16. Liu, L., Xu, Y., Liu, Z., Chen, J., Zhang, Y., Zhu, J., et al. (.2011). IL12 polymorphisms, HBV infection and risk of hepatocellular carcinoma in a high-risk Chinese population. Int J Cancer 128, 1692-1696
17. Miteva, L., Stanilov, N., Deliysky, T., Mintchev, N., and Stanilova, S. (.2009). Association of polymorphisms in regulatory regions of interleukin-12p40 gene and cytokine serum level with colorectal cancer. Cancer Invest 27, 924-931
18. Murakami, S., Okubo, K., Tsuji, Y., Sakata, H., Hamada, S., and Hirayama, R. (.2004). Serum interleukin-12 levels in patients with gastric cancer. Surg Today 34, 1014-1019
19. Nakahira, M., Tomura, M., Iwasaki, M., Ahn, H.J., Bian, Y., Hamaoka, T., et al. (.2001). An absolute requirement for STAT4 and a role for IFN-gamma as an amplifying factor in IL-12 induction of the functional IL-18 receptor complex. J Immunol 167, 1306-1312
20. Ognjanovic, S., Yuan, J.M., Chaptman, A.K., Fan, Y., and Yu, M.C. (.2009). Genetic polymorphisms in the cytokine genes and risk of hepatocellular carcinoma in low-risk non-Asians of USA. Carcinogenesis 30, 758-762
21. Ottaviani, G., and Jaffe, N. (.2009). The epidemiology of osteosarcoma. Cancer Treat Res 152, 3-13
22. Roszak, A., Mostowska, A., Sowinska, A., Lianeri, M., and Jagodzinski, P.P. (.2012). Contribution of IL12A and IL12B polymorphisms to the risk of cervical cancer. Pathol Oncol Res 18, 997-1002
23. Schlecht, N.F., Kulaga, S., Robitaille, J., Ferreira, S., Santos, M., Miyamura, R.A., et al. (.2001). Persistent human papillomavirus infection as a predictor of cervical intraepithelial neoplasia. JAMA 286, 3106-3114
24. Sima, X., Xu, J., Li, Q., Luo, L., Liu, J., and You, C. (.2012). Genegene interactions between interleukin-12A and interleukin-12B with the risk of brain tumor. DNA Cell Biol 31, 219-223
25. Stanilov, N.S., Miteva, L.D., Dobreva, Z.G., Jovchev, J.P., Cirovski, G.M., Stanilova, S.A. (.2012). Monocytes expression of IL-12 related and IL-10 genes in association with development of colorectal cancer. Mol Biol Rep 12, 10895-10902
26. Takaoka, A., Hayakawa, S., Yanai, H., Stoiber, D., Negishi, H., Kikuchi, H., et al. (.2003). Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. Nature 424, 516-523
27. Tao, Y.P., Wang, W.L., Li, S.Y., Zhang, J., Shi, Q.Z., Zhao, F., et al. (.2012). Associations between polymorphisms in IL-12A, IL-12B, IL-12Rbeta1, IL-27 gene and serum levels of IL-12p40, IL-27p28 with esophageal cancer. J Cancer Res Clin Oncol 138, 1891-1900
28. Trinchieri, G. (.2003). Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 3, 133-146
29. Wang, E.Y., Liang, W.B., and Zhang, L. (.2012). Association between single-nucleotide polymorphisms in interleukin-12A and risk of chronic obstructive pulmonary disease. DNA Cell Biol 31, 1475-1479
30. Wei, Y.S., Lan, Y., Luo, B., Lu, D., and Nong, H.B. (.2009). Association of variants in the interleukin-27 and interleukin-12 gene with nasopharyngeal carcinoma. Mol Carcinog 48, 751-757
31. Younes, A., Pro, B., Robertson, M.J., Flinn, I.W., Romaguera, J.E., Hagemeister, F., et al. (.2004). Phase II clinical trial of interleukin-12 in patients with relapsed and refractory non- Hodgkin's lymphoma and Hodgkin's disease. Clin Cancer Res 16, 5432-5438
32. Yuzhalin, A.E., and Kutikhin, A.G. (.2012). Interleukin-12: Clinical usage and molecular markers of cancer susceptibility. Growth Factors 30, 176-191
33. Zabala, M., Lasarte, J.J., Perret, C., Sola, J., Berraondo, P., Alfaro, M., et al. (.2007). Induction of immunosuppressive molecules and regulatory T cells counteracts the antitumor effect of interleukin-12-based gene therapy in a transgenic mouse model of liver cancer. J Hepatol 47, 807-815
34. Zhao, B., Meng, L.Q., Huang, H.N., Pan, Y., and Xu, Q.Q. (.2009 A novel functional polymorphism, 16974 A/C, in the interleukin- 12-3' untranslated region is associated with risk of glioma. DNA Cell Biol 28, 335-341