Contribution of IL12A and IL12B polymorphisms to the risk of cervical cancer

Pathology and Oncology Research

Volumn 18, Issue 4, 2012, Pages 997-1002

  Roszak, Andrzej ^a,b   Mostowska, Adrianna ^b   Sowińska, Anna ^b   Lianeri, Margarita ^b   Jagodziński, Pawel P ^b  

^a GREATER POLAND CANCER CENTRE   (Poland)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Cervical carcinoma; IL12A and IL12B; Polymorphisms

Indexed keywords

INTERLEUKIN 12P35; INTERLEUKIN 12P40;

3' UNTRANSLATED REGION; ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CANCER GROWTH; CANCER RISK; CARCINOGENESIS; CONTROLLED STUDY; ETHNIC GROUP; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HUMAN; INTERLEUKIN 12A GENE; INTERLEUKIN 12B GENE; MAJOR CLINICAL STUDY; POLISH; RISK ASSESSMENT; UTERINE CERVIX CANCER;

ADULT; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERLEUKIN-12 SUBUNIT P35; INTERLEUKIN-12 SUBUNIT P40; LOGISTIC MODELS; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; UTERINE CERVICAL NEOPLASMS;

EID: 84868507434     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-012-9532-x     Document Type: Article

References (53)

1. Arbyn M, Raifu AO, Autier P et al (2007) Burden of cervical cancer in Europe: estimates for 2004. Ann Oncol 18:1708-1715
2. Muñoz N, Bosch FX, de Sanjosé S et al (2003) Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med 348:518-527
3. Walboomers JM, Jacobs MV, Manos MM et al (1999) Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 189:12-19
4. Giuliano AR, Harris R, Sedjo RL et al (2002) Incidence, prevalence, and clearance of type-specific human papillomavirus infections: the Young Women's Health Study. J Infect Dis 186:462-469
5. Magnusson PK, Lichtenstein P, Gyllensten UB (2000) Heritability of cervical tumours. Int J Cancer 88:698-701
6. Hemminki K, Chen B (2006) Familial risks for cervical tumors in full and half siblings: etiologic apportioning. Cancer Epidemiol Biomarkers Prev 15:1413-1414
7. Castellsague X, Munoz N (2003) Chapter 3: cofactors in human papillomavirus carcinogenesis-role of parity, oral contraceptives, and tobacco smoking. J Natl Cancer Inst Monogr 20-28
8. Moreno V, Bosch FX, Munoz N et al (2002) Effect of oral contraceptives on risk of cervical cancer in women with human papillomavirus infection: the IARC multicentric case-control study. Lancet 359:1085-1092
9. Wu TC, Kurman RJ (1997) Analysis of cytokine profiles in patients with human papillomavirus-associated neoplasms. J Natl Cancer Inst 89:185-187
10. Scott M, Stites DP, Moscicki AB (1999) Th1 cytokine patterns in cervical human papillomavirus infection. Clin Diagn Lab Immunol 6:751-755
11. Trinchieri G (1998) Interleukin-12: a cytokine at the interface of inflammmation and immunity. Adv Immunol 70:83-243
12. Trinchieri G (2003) Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 3:133-146
13. Macatonia SE, Hosken NA, Litton M et al (1995) Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol 154:5071-5079
14. D'Andrea A, Rengaraju M, Valiante NM et al (1992) Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J Exp Med 176:1387-1398
15. Cassatella MA, Meda L, Gasperini S et al (1995) Interleukin-12 production by human polymorphonuclear leukocytes. Eur J Immunol 25:1-5
16. Colombo MP, Trinchieri G (2002) Interleukin-12 in anti-tumor immunity and immunotherapy. Cytokine Growth Factor Rev 13:155-168
17. Brunda MJ, Luistro L, Warrier RR et al (1993) Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med 178:1223-1230
18. Imagawa Y, Satake K, Kato Yet al (2004) Antitumor and antiangiogenic effects of interleukin 12 gene therapy in murine head and neck carcinoma model. Auris Nasus Larynx 31:239-245
19. Sieburth D, Jabs EW, Warrington JA et al (1992) Assignment of genes encoding a unique cytokine (IL12) composed of two unrelated subunits to chromosomes 3 and 5. Genomics 14:59-62
20. Lan Q, Zheng T, Rothman N et al (2006) Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma. Blood 107:4101-4108
21. Purdue MP, Lan Q, Kricker A et al (2007) Polymorphisms in immune function genes and risk of non-Hodgkin lymphoma: findings from the New South Wales non-Hodgkin lymphoma study. Carcinogenesis 28:704-712
22. Nieters A, Yuan JM, Sun CL et al (2005) Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association. Cancer 103:740-748
23. Lee KM, Shen M, Chapman RS et al (2007) Polymorphisms in immunoregulatory genes, smoky coal exposure and lung cancer risk in Xuan Wei, China. Carcinogenesis 28:1437-1441
24. Hou L, El-Omar EM, Chen J et al (2007) Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer. Carcinogenesis 28:118-123
25. Navaglia F, Basso D, Zambon CF et al (2005) Interleukin 12 gene polymorphisms enhance gastric cancer risk in H pylori infected individuals. J Med Genet 42:503-510
26. Brown EE, Fallin D, Ruczinski I et al (2006) Associations of classic Kaposi sarcoma with common variants in genes that modulate host immunity. Cancer Epidemiol Biomark Prev 15:926-934
27. Howell WM, Turner SJ, Theaker JM et al (2003) Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma. Eur J Immunogenet 30:409-414
28. Landi S, Gemignani F, Bottari F et al (2006) Polymorphisms within inflammatory genes and colorectal cancer. J Negat Results Biomed 5:15
29. Ben Chaaben A, Busson M, Douik H et al (2011) Association of IL-12p40 +1188 A/C polymorphism with nasopharyngeal cancer risk and tumor extension. Tissue Antigens 78:148-151
30. Chen X, Han S,Wang S et al (2009) Interactions of IL-12A and IL-12B polymorphisms on the risk of cervical cancer in Chinese women. Clin Cancer Res 15:400-405
31. Kordi Tamandani DM, Shekari M, Suri Vet al (2009) Interleukin-12 gene polymorphism and cervical cancer risk. Am J Clin Oncol
32. Han SS, Cho EY, Lee TS et al (2008) Interleukin-12 p40 gene (IL12B) polymorphisms and the risk of cervical caner in Korean women. Eur J Obstet Gynecol Reprod Biol 140:71-75
33. Noguchi Y, Jungbluth A, Richards EC et al (1996) Effect of interleukin 12 on tumor induction by 3-methylcholanthrene. Proc Natl Acad Sci USA 93:11798-11801
34. Nanni P, Nicoletti G, De Giovanni C et al (2001) Combined allogeneic tumor cell vaccination and systemic interleukin 12 prevents mammary carcinogenesis in HER-2/neu transgenic mice. J Exp Med 194:1195-1205
35. Bais AG, Beckmann I, Ewing PC et al (2007) Cytokine release in HR-HPV(+) women without and with cervical dysplasia (CIN II and III) or carcinoma, compared with HR-HPV(-) controls. Mediators Inflamm 24147
36. Kadish AS, Timmins P, Wang Yet al (2002) Regression of cervical intraepithelial neoplasia and loss of human papillomavirus (HPV) infection is associated with cell-mediated immune responses to an HPV type 16 E7 peptide. Cancer Epidemiol Biomark Prev 11:483-488
37. Jin HS, Park EK, Lee JM et al (2005) Immunization with adenoviral vectors carrying recombinant IL-12 and E7 enhanced the antitumor immunity to human papillomavirus 16-associated tumor. Gynecol Oncol 97:559-567
38. Indrová M, Bieblová J, Rossowska J et al (2009) HPV 16-associated tumours: IL-12 can repair the absence of cytotoxic and proliferative responses of tumour infiltrating cells after chemotherapy. Int J Oncol 34:173-179
39. Mikyšková R, Indrová M, Símová J et al (2011) Genetically modified tumour vaccines producing IL-12 augment chemotherapy of HPV16-associated tumours with gemcitabine. Oncol Rep 25:1683-1689
40. Chen T, Liang W, Gao L et al (2011) Association of single nucleotide polymorphisms in interleukin 12 (IL-12A and -B) with asthma in a Chinese population. Hum Immunol 72:603-606
41. Morris GA, Edwards DR, Hill PC et al (2011) Interleukin 12B (IL12B) genetic variation and pulmonary tuberculosis: a study of cohorts from The Gambia, Guinea-Bissau, United States and Argentina. PLoS One 6:e16656
42. Morahan G, McKinnon E, Berry J et al (2009) Type I diabetes genetics consortium. Evaluation of IL12B as a candidate type I diabetes susceptibility gene using data from the type I diabetes genetics consortium. Genes Immun 10(Suppl 1):S64-S68
43. Nair RP, Stuart PE, Kullavanijaya P et al (2010) Genetic evidence for involvement of the IL23 pathway in Thai psoriatics. Arch Dermatol Res 302:139-143
44. Filer C, Ho P, Smith RL et al (2008) Investigation of association of the IL12B and IL23R genes with psoriatic arthritis. Arthritis Rheum 58:3705-3709
45. Phawong C, Ouma C, Tangteerawatana P et al (2010) Haplotypes of IL12B promoter polymorphisms condition susceptibility to severe malaria and functional changes in cytokine levels in Thai adults. Immunogenetics 62:345-356
46. Cerhan JR, Wang S, Maurer MJ et al (2007) Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival. Blood 109:5439-5446
47. Morahan G, Huang D, Ymer SI et al (2001) Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele. Nat Genet 27:218-221
48. Davoodi-Semiromi A, Yang JJ, She JX (2002) IL-12p40 is associated with type 1 diabetes in Caucasian-American families. Diabetes 51:2334-2336
49. Seegers D, Zwiers A, Strober Wet al (2002) ATaqI polymorphism in the 3'UTR of the IL-12 p40 gene correlates with increased IL-12 secretion. Genes Immun 3:419-423
50. Yilmaz V, Yentur SP, Saruhan-Direskeneli G (2005) IL-12 and IL-10 polymorphisms and their effects on cytokine production. Cytokine 30:188-194
51. Guo T, Yang S, Liu N et al (2011) Association study of interleukin-12A gene polymorphisms with Graves' disease in two Chinese populations. Clin Endocrinol (Oxf) 74:125-129
52. Chen Y, Zheng T, Lan Q et al (2011) Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma. Blood 117:585-590
53. Liu L, Xu Y, Liu Z et al (2011) IL12 polymorphisms, HBV infection and risk of hepatocellular carcinoma in a high-risk Chinese population. Int J Cancer 128:1692-1696