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Volumn 8, Issue 9, 2013, Pages

A Three-Marker FISH Panel Detects More Genetic Aberrations of AR, PTEN and TMPRSS2/ERG in Castration-Resistant or Metastatic Prostate Cancers than in Primary Prostate Tumors

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

EID: 84884790690     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074671     Document Type: Article
Times cited : (18)

References (38)
  • 1
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, et al. (2005) Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310: 644-648.
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1    Rhodes, D.R.2    Perner, S.3    Dhanasekaran, S.M.4    Mehra, R.5
  • 2
    • 38049123346 scopus 로고    scopus 로고
    • Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer
    • Attard G, Clark J, Ambroisine L, Fisher G, Kovacs G, et al. (2008) Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer. Oncogene 27: 253-263.
    • (2008) Oncogene , vol.27 , pp. 253-263
    • Attard, G.1    Clark, J.2    Ambroisine, L.3    Fisher, G.4    Kovacs, G.5
  • 3
    • 70350109641 scopus 로고    scopus 로고
    • ETS gene fusions in prostate cancer
    • Clark JP, Cooper CS, (2009) ETS gene fusions in prostate cancer. Nat Rev Urol 6: 429-439.
    • (2009) Nat Rev Urol , vol.6 , pp. 429-439
    • Clark, J.P.1    Cooper, C.S.2
  • 4
    • 60549107254 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy
    • Gopalan A, Leversha MA, Satagopan JM, Zhou Q, Al-Ahmadie HA, et al. (2009) TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy. Cancer Res 69: 1400-1406.
    • (2009) Cancer Res , vol.69 , pp. 1400-1406
    • Gopalan, A.1    Leversha, M.A.2    Satagopan, J.M.3    Zhou, Q.4    Al-Ahmadie, H.A.5
  • 5
    • 77950518687 scopus 로고    scopus 로고
    • Prevalence of TMPRSS2-ERG and SLC45A3-ERG gene fusions in a large prostatectomy cohort
    • C J.L
    • Esgueva R, Perner S, C JL, Scheble V, Stephan C, et al. (2010) Prevalence of TMPRSS2-ERG and SLC45A3-ERG gene fusions in a large prostatectomy cohort. Mod Pathol 23: 539-546.
    • (2010) Mod Pathol , vol.23 , pp. 539-546
    • Esgueva, R.1    Perner, S.2    Scheble, V.3    Stephan, C.4
  • 6
    • 0028944138 scopus 로고
    • In vivo amplification of the androgen receptor gene and progression of human prostate cancer
    • Visakorpi T, Hyytinen E, Koivisto P, Tanner M, Keinanen R, et al. (1995) In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat Genet 9: 401-406.
    • (1995) Nat Genet , vol.9 , pp. 401-406
    • Visakorpi, T.1    Hyytinen, E.2    Koivisto, P.3    Tanner, M.4    Keinanen, R.5
  • 7
    • 0033557839 scopus 로고    scopus 로고
    • Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays
    • Bubendorf L, Kononen J, Koivisto P, Schraml P, Moch H, et al. (1999) Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays. Cancer Res 59: 803-806.
    • (1999) Cancer Res , vol.59 , pp. 803-806
    • Bubendorf, L.1    Kononen, J.2    Koivisto, P.3    Schraml, P.4    Moch, H.5
  • 8
    • 34548299547 scopus 로고    scopus 로고
    • FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome
    • Yoshimoto M, Cunha IW, Coudry RA, Fonseca FP, Torres CH, et al. (2007) FISH analysis of 107 prostate cancers shows that PTEN genomic deletion is associated with poor clinical outcome. Br J Cancer 97: 678-685.
    • (2007) Br J Cancer , vol.97 , pp. 678-685
    • Yoshimoto, M.1    Cunha, I.W.2    Coudry, R.A.3    Fonseca, F.P.4    Torres, C.H.5
  • 9
    • 67650917081 scopus 로고    scopus 로고
    • PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer
    • Sircar K, Yoshimoto M, Monzon FA, Koumakpayi IH, Katz RL, et al. (2009) PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer. J Pathol 218: 505-513.
    • (2009) J Pathol , vol.218 , pp. 505-513
    • Sircar, K.1    Yoshimoto, M.2    Monzon, F.A.3    Koumakpayi, I.H.4    Katz, R.L.5
  • 10
    • 56649091295 scopus 로고    scopus 로고
    • Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome
    • Yoshimoto M, Joshua AM, Cunha IW, Coudry RA, Fonseca FP, et al. (2008) Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome. Mod Pathol 21: 1451-1460.
    • (2008) Mod Pathol , vol.21 , pp. 1451-1460
    • Yoshimoto, M.1    Joshua, A.M.2    Cunha, I.W.3    Coudry, R.A.4    Fonseca, F.P.5
  • 11
    • 76949106361 scopus 로고    scopus 로고
    • Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer
    • Reid AH, Attard G, Ambroisine L, Fisher G, Kovacs G, et al. (2010) Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer. Br J Cancer 102: 678-684.
    • (2010) Br J Cancer , vol.102 , pp. 678-684
    • Reid, A.H.1    Attard, G.2    Ambroisine, L.3    Fisher, G.4    Kovacs, G.5
  • 12
    • 79955975429 scopus 로고    scopus 로고
    • Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer
    • Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, et al. (2011) Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell 19: 575-586.
    • (2011) Cancer Cell , vol.19 , pp. 575-586
    • Carver, B.S.1    Chapinski, C.2    Wongvipat, J.3    Hieronymus, H.4    Chen, Y.5
  • 13
    • 79958764107 scopus 로고    scopus 로고
    • Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth
    • Mulholland DJ, Tran LM, Li Y, Cai H, Morim A, et al. (2011) Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell 19: 792-804.
    • (2011) Cancer Cell , vol.19 , pp. 792-804
    • Mulholland, D.J.1    Tran, L.M.2    Li, Y.3    Cai, H.4    Morim, A.5
  • 14
    • 80054951975 scopus 로고    scopus 로고
    • Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers
    • Wang Y, Romigh T, He X, Tan MH, Orloff MS, et al. (2011) Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers. Oncogene 30: 4327-4338.
    • (2011) Oncogene , vol.30 , pp. 4327-4338
    • Wang, Y.1    Romigh, T.2    He, X.3    Tan, M.H.4    Orloff, M.S.5
  • 15
    • 44449108773 scopus 로고    scopus 로고
    • Differential expression of angiogenesis associated genes in prostate cancer bone, liver and lymph node metastases
    • Morrissey C, True LD, Roudier MP, Coleman IM, Hawley S, et al. (2008) Differential expression of angiogenesis associated genes in prostate cancer bone, liver and lymph node metastases. Clin Exp Metastasis 25: 377-388.
    • (2008) Clin Exp Metastasis , vol.25 , pp. 377-388
    • Morrissey, C.1    True, L.D.2    Roudier, M.P.3    Coleman, I.M.4    Hawley, S.5
  • 17
    • 84873466127 scopus 로고    scopus 로고
    • A novel four-color fluorescence in situ hybridization assay for the detection of TMPRSS2 and ERG rearrangements in prostate cancer
    • Qu X, Randhawa G, Friedman C, O'Hara-Larrivee S, Kroeger K, et al. (2013) A novel four-color fluorescence in situ hybridization assay for the detection of TMPRSS2 and ERG rearrangements in prostate cancer. Cancer Genet 206: 1-11.
    • (2013) Cancer Genet , vol.206 , pp. 1-11
    • Qu, X.1    Randhawa, G.2    Friedman, C.3    O'Hara-Larrivee, S.4    Kroeger, K.5
  • 18
    • 78649888666 scopus 로고    scopus 로고
    • The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
    • Sharma A, Yeow WS, Ertel A, Coleman I, Clegg N, et al. (2010) The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression. J Clin Invest 120: 4478-4492.
    • (2010) J Clin Invest , vol.120 , pp. 4478-4492
    • Sharma, A.1    Yeow, W.S.2    Ertel, A.3    Coleman, I.4    Clegg, N.5
  • 19
    • 0024205301 scopus 로고
    • Models for longitudinal data: a generalized estimating equation approach
    • Zeger SL, Liang KY, Albert PS, (1988) Models for longitudinal data: a generalized estimating equation approach. Biometrics 44: 1049-1060.
    • (1988) Biometrics , vol.44 , pp. 1049-1060
    • Zeger, S.L.1    Liang, K.Y.2    Albert, P.S.3
  • 21
    • 84863723010 scopus 로고    scopus 로고
    • The mutational landscape of lethal castration-resistant prostate cancer
    • Grasso CS, Wu YM, Robinson DR, Cao X, Dhanasekaran SM, et al. (2012) The mutational landscape of lethal castration-resistant prostate cancer. Nature 487: 239-243.
    • (2012) Nature , vol.487 , pp. 239-243
    • Grasso, C.S.1    Wu, Y.M.2    Robinson, D.R.3    Cao, X.4    Dhanasekaran, S.M.5
  • 22
    • 50549095607 scopus 로고    scopus 로고
    • Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer
    • FitzGerald LM, Agalliu I, Johnson K, Miller MA, Kwon EM, et al. (2008) Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer. BMC Cancer 8: 230.
    • (2008) BMC Cancer , vol.8 , pp. 230
    • FitzGerald, L.M.1    Agalliu, I.2    Johnson, K.3    Miller, M.A.4    Kwon, E.M.5
  • 23
    • 70350223620 scopus 로고    scopus 로고
    • Comparative analyses of chromosome alterations in soft-tissue metastases within and across patients with castration-resistant prostate cancer
    • Holcomb IN, Young JM, Coleman IM, Salari K, Grove DI, et al. (2009) Comparative analyses of chromosome alterations in soft-tissue metastases within and across patients with castration-resistant prostate cancer. Cancer Res 69: 7793-7802.
    • (2009) Cancer Res , vol.69 , pp. 7793-7802
    • Holcomb, I.N.1    Young, J.M.2    Coleman, I.M.3    Salari, K.4    Grove, D.I.5
  • 24
    • 45549090259 scopus 로고    scopus 로고
    • Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer
    • Mehra R, Tomlins SA, Yu J, Cao X, Wang L, et al. (2008) Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer. Cancer Res 68: 3584-3590.
    • (2008) Cancer Res , vol.68 , pp. 3584-3590
    • Mehra, R.1    Tomlins, S.A.2    Yu, J.3    Cao, X.4    Wang, L.5
  • 25
    • 33749029695 scopus 로고    scopus 로고
    • TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer
    • Perner S, Demichelis F, Beroukhim R, Schmidt FH, Mosquera JM, et al. (2006) TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer. Cancer Res 66: 8337-8341.
    • (2006) Cancer Res , vol.66 , pp. 8337-8341
    • Perner, S.1    Demichelis, F.2    Beroukhim, R.3    Schmidt, F.H.4    Mosquera, J.M.5
  • 26
    • 48349124823 scopus 로고    scopus 로고
    • Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate cancer patients
    • Holcomb IN, Grove DI, Kinnunen M, Friedman CL, Gallaher IS, et al. (2008) Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate cancer patients. Cancer Res 68: 5599-5608.
    • (2008) Cancer Res , vol.68 , pp. 5599-5608
    • Holcomb, I.N.1    Grove, D.I.2    Kinnunen, M.3    Friedman, C.L.4    Gallaher, I.S.5
  • 27
    • 33645231294 scopus 로고    scopus 로고
    • The PTEN gene in locally progressive prostate cancer is preferentially inactivated by bi-allelic gene deletion
    • Verhagen PC, van Duijn PW, Hermans KG, Looijenga LH, van Gurp RJ, et al. (2006) The PTEN gene in locally progressive prostate cancer is preferentially inactivated by bi-allelic gene deletion. J Pathol 208: 699-707.
    • (2006) J Pathol , vol.208 , pp. 699-707
    • Verhagen, P.C.1    van Duijn, P.W.2    Hermans, K.G.3    Looijenga, L.H.4    van Gurp, R.J.5
  • 28
    • 33747842237 scopus 로고    scopus 로고
    • Interphase FISH analysis of PTEN in histologic sections shows genomic deletions in 68% of primary prostate cancer and 23% of high-grade prostatic intra-epithelial neoplasias
    • Yoshimoto M, Cutz JC, Nuin PA, Joshua AM, Bayani J, et al. (2006) Interphase FISH analysis of PTEN in histologic sections shows genomic deletions in 68% of primary prostate cancer and 23% of high-grade prostatic intra-epithelial neoplasias. Cancer Genet Cytogenet 169: 128-137.
    • (2006) Cancer Genet Cytogenet , vol.169 , pp. 128-137
    • Yoshimoto, M.1    Cutz, J.C.2    Nuin, P.A.3    Joshua, A.M.4    Bayani, J.5
  • 29
    • 66749100105 scopus 로고    scopus 로고
    • Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
    • King JC, Xu J, Wongvipat J, Hieronymus H, Carver BS, et al. (2009) Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. Nat Genet 41: 524-526.
    • (2009) Nat Genet , vol.41 , pp. 524-526
    • King, J.C.1    Xu, J.2    Wongvipat, J.3    Hieronymus, H.4    Carver, B.S.5
  • 30
    • 69249142732 scopus 로고    scopus 로고
    • Genetic profile identification in clinically localized prostate carcinoma
    • Gallucci M, Merola R, Leonardo C, De Carli P, Farsetti A, et al. (2009) Genetic profile identification in clinically localized prostate carcinoma. Urol Oncol 27: 502-508.
    • (2009) Urol Oncol , vol.27 , pp. 502-508
    • Gallucci, M.1    Merola, R.2    Leonardo, C.3    De Carli, P.4    Farsetti, A.5
  • 31
    • 33646511541 scopus 로고    scopus 로고
    • Cytogenetic profiles as additional markers to pathological features in clinically localized prostate carcinoma
    • Gallucci M, Merola R, Farsetti A, Orlandi G, Sentinelli S, et al. (2006) Cytogenetic profiles as additional markers to pathological features in clinically localized prostate carcinoma. Cancer Lett 237: 76-82.
    • (2006) Cancer Lett , vol.237 , pp. 76-82
    • Gallucci, M.1    Merola, R.2    Farsetti, A.3    Orlandi, G.4    Sentinelli, S.5
  • 32
    • 0036772932 scopus 로고    scopus 로고
    • Amplification of the androgen receptor gene in bone metastases from hormone-refractory prostate cancer
    • Brown RS, Edwards J, Dogan A, Payne H, Harland SJ, et al. (2002) Amplification of the androgen receptor gene in bone metastases from hormone-refractory prostate cancer. J Pathol 198: 237-244.
    • (2002) J Pathol , vol.198 , pp. 237-244
    • Brown, R.S.1    Edwards, J.2    Dogan, A.3    Payne, H.4    Harland, S.J.5
  • 33
    • 0141954183 scopus 로고    scopus 로고
    • Androgen receptor gene amplification and protein expression in recurrent prostate cancer
    • Ford OH, (2003) Androgen receptor gene amplification and protein expression in recurrent prostate cancer. J Urol 170: 1817-1821.
    • (2003) J Urol , vol.170 , pp. 1817-1821
    • Ford, O.H.1
  • 34
    • 79959660044 scopus 로고    scopus 로고
    • Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas
    • Chaux A, Albadine R, Toubaji A, Hicks J, Meeker A, et al. (2011) Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas. Am J Surg Pathol 35: 1014-1020.
    • (2011) Am J Surg Pathol , vol.35 , pp. 1014-1020
    • Chaux, A.1    Albadine, R.2    Toubaji, A.3    Hicks, J.4    Meeker, A.5
  • 35
    • 66749188650 scopus 로고    scopus 로고
    • Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
    • Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, et al. (2009) Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat Genet 41: 619-624.
    • (2009) Nat Genet , vol.41 , pp. 619-624
    • Carver, B.S.1    Tran, J.2    Gopalan, A.3    Chen, Z.4    Shaikh, S.5
  • 36
    • 67349257845 scopus 로고    scopus 로고
    • Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer
    • Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, et al. (2009) Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med 15: 559-565.
    • (2009) Nat Med , vol.15 , pp. 559-565
    • Liu, W.1    Laitinen, S.2    Khan, S.3    Vihinen, M.4    Kowalski, J.5
  • 37
    • 0038721560 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of end-stage prostate carcinoma metastatic to bone
    • Roudier MP, True LD, Higano CS, Vesselle H, Ellis W, et al. (2003) Phenotypic heterogeneity of end-stage prostate carcinoma metastatic to bone. Hum Pathol 34: 646-653.
    • (2003) Hum Pathol , vol.34 , pp. 646-653
    • Roudier, M.P.1    True, L.D.2    Higano, C.S.3    Vesselle, H.4    Ellis, W.5
  • 38
    • 84871927805 scopus 로고    scopus 로고
    • Exome Sequencing of Prostate Cancer Supports the Hypothesis of Independent Tumour Origins
    • Lindberg J, Klevebring D, Liu W, Neiman M, Xu J, et al. (2012) Exome Sequencing of Prostate Cancer Supports the Hypothesis of Independent Tumour Origins. Eur Urol.
    • (2012) Eur Urol
    • Lindberg, J.1    Klevebring, D.2    Liu, W.3    Neiman, M.4    Xu, J.5


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