Transplantation of mesenchymal cells rejuvenated by the overexpression of telomerase and myocardin promotes revascularization and tissue repair in a murine model of hindlimb ischemia

Circulation Research

Volumn 113, Issue 7, 2013, Pages 902-914

  Madonna, Rosalinda ^a,c   Taylor, Doris A ^a   Geng, Yong Jian ^a,b   De Caterina, Raffaele ^a,c   Shelat, Harnath ^a   Perin, Emerson C ^a   Willerson, James T ^a,b  

^a TEXAS HEART INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CHIETI   (Italy)

Author keywords

adipose derived mesenchymal stem cells; aging; bone marrow stem cells; hindlimb ischemia; mesenchymal stem cells; myocardin; telomerase

Indexed keywords

APOLIPOPROTEIN E; BROXURIDINE; LENTIVIRUS VECTOR; MYOCARDIN; TELOMERASE REVERSE TRANSCRIPTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ASSAY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CLONOGENIC ASSAY; CONTROLLED STUDY; FLOW CYTOMETRY; GENE OVEREXPRESSION; GENETIC TRANSDUCTION; HINDLIMB; LEG REVASCULARIZATION; LIMB ISCHEMIA; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; MURINE MODEL; NONHUMAN; PRIORITY JOURNAL; THERAPY EFFECT; TISSUE REPAIR;

ADIPOSE-DERIVED MESENCHYMAL STEM CELLS; AGING; BONE MARROW STEM CELLS; HINDLIMB ISCHEMIA; MESENCHYMAL STEM CELLS; MYOCARDIN; TELOMERASE;

ADIPOSE TISSUE; ANIMALS; CELL DIFFERENTIATION; HINDLIMB; ISCHEMIA; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; NUCLEAR PROTEINS; TELOMERASE; TRANS-ACTIVATORS;

EID: 84884785189     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.301690     Document Type: Article

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