Rationale and design of a randomized trial on the impact of aldosterone antagonism on cardiac structure and function in diabetic cardiomyopathy

Cardiovascular Diabetology

Volumn 12, Issue 1, 2013, Pages

  Leung, Melissa ^a,b   Wong, Vincent W ^a,b,d   Heritier, Stephane ^c   Mihailidou, Anastasia S ^d   Leung, Dominic Y ^a,b  

^a LIVERPOOL HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

Aldosterone antagonism; Collagen; Diabetes; Echocardiography; Heart failure; Left ventricular function

Indexed keywords

ALDOSTERONE RECEPTOR; COLLAGEN; EPLERENONE; PLACEBO;

ADULT; ARTICLE; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DOUBLE BLIND PROCEDURE; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG SELECTIVITY; DYSPNEA; EARLY DIAGNOSIS; EXERCISE; FEMALE; HEART ATRIUM FIBRILLATION; HUMAN; INCIDENCE; LEFT VENTRICULAR DIASTOLIC DYSFUNCTION; LEFT VENTRICULAR SYSTOLIC DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; METABOLIC REGULATION; MULTICENTER STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; OPTIMAL DRUG DOSE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TABLET; TISSUE DOPPLER IMAGING; TREATMENT DURATION; TURNOVER TIME;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CARDIOVASCULAR AGENTS; CLINICAL PROTOCOLS; COLLAGEN; DIABETES MELLITUS, TYPE 2; DIABETIC CARDIOMYOPATHIES; DIASTOLE; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; ECHOCARDIOGRAPHY, DOPPLER; FIBROSIS; HUMANS; MINERALOCORTICOID RECEPTOR ANTAGONISTS; MYOCARDIUM; NEW SOUTH WALES; PROSPECTIVE STUDIES; RECOVERY OF FUNCTION; RESEARCH DESIGN; SPIRONOLACTONE; SYSTOLE; TIME FACTORS; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT;

EID: 84884768034     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-12-139     Document Type: Article

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