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Volumn 4, Issue 12, 2011, Pages 1239-1249

A randomized study of the beneficial effects of aldosterone antagonism on lv function, structure, and fibrosis markers in metabolic syndrome

Author keywords

collagen; echocardiography; hypertension; metabolic syndrome; obesity

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BIGUANIDE; CALCIUM ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; FIBRIC ACID DERIVATIVE; HYDROCHLOROTHIAZIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INDAPAMIDE; PLACEBO; PROCOLLAGEN TYPE 1 CARBOXY TERMINAL PROPEPTIDE; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; SPIRONOLACTONE; SULFONYLUREA; UNCLASSIFIED DRUG;

EID: 83455172574     PISSN: 1936878X     EISSN: 18767591     Source Type: Journal    
DOI: 10.1016/j.jcmg.2011.08.014     Document Type: Article
Times cited : (113)

References (35)
  • 1
    • 29044448568 scopus 로고    scopus 로고
    • Myocardial and vascular dysfunction and exercise capacity in the metabolic syndrome
    • DOI 10.1016/j.amjcard.2005.07.091, PII S0002914905015195
    • C.Y. Wong, T. O'Moore-Sullivan, Z.Y. Fang, B. Haluska, R. Leano, T.H. Marwick Myocardial and vascular dysfunction and exercise capacity in the metabolic syndrome Am J Cardiol 96 2005 1686 1691 (Pubitemid 41790392)
    • (2005) American Journal of Cardiology , vol.96 , Issue.12 , pp. 1686-1691
    • Wong, C.Y.1    O'Moore-Sullivan, T.2    Fang, Z.Y.3    Haluska, B.4    Leano, R.5    Marwick, T.H.6
  • 3
    • 50349090701 scopus 로고    scopus 로고
    • Cardiac markers of pre-clinical disease in adolescents with the metabolic syndrome: The Strong Heart study
    • M. Chinali, G. de Simone, M.J. Roman Cardiac markers of pre-clinical disease in adolescents with the metabolic syndrome: the Strong Heart study J Am Coll Cardiol 52 2008 932 938
    • (2008) J Am Coll Cardiol , vol.52 , pp. 932-938
    • Chinali, M.1    De Simone, G.2    Roman, M.J.3
  • 5
    • 77950447086 scopus 로고    scopus 로고
    • The impact of metabolic syndrome on left ventricular myocardial performance
    • C. Voulgari, I. Moyssakis, A. Papazafiropoulou The impact of metabolic syndrome on left ventricular myocardial performance Diabetes Metab Res Rev 26 2010 121 127
    • (2010) Diabetes Metab Res Rev , vol.26 , pp. 121-127
    • Voulgari, C.1    Moyssakis, I.2    Papazafiropoulou, A.3
  • 6
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: Findings from the Third National Health and Nutrition Examination Survey
    • E.S. Ford, W.H. Giles, W.H. Dietz Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey JAMA 287 2002 356 359 (Pubitemid 34251969)
    • (2002) Journal of the American Medical Association , vol.287 , Issue.3 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 8
    • 0034745049 scopus 로고    scopus 로고
    • Aldosterone escape during angiostensin-converting enzyme inhibitor therapy in essential hypertensive patients with left ventricular hypertrophy
    • A. Sato, T. Saruta Aldosterone escape during angiotensin-converting enzyme inhibitor therapy in essential hypertensive patients with left ventricular hypertrophy J Int Med Res 29 2001 13 21 (Pubitemid 32236891)
    • (2001) Journal of International Medical Research , vol.29 , Issue.1 , pp. 13-21
    • Sato, A.1    Saruta, T.2
  • 10
    • 4043184149 scopus 로고    scopus 로고
    • The clinical implications of aldosterone escape in congestive heart failure
    • DOI 10.1016/j.ejheart.2004.04.013, PII S1388984204001278
    • A.D. Struthers The clinical implications of aldosterone escape in congestive heart failure Eur J Heart Fail 6 2004 539 545 (Pubitemid 39070505)
    • (2004) European Journal of Heart Failure , vol.6 , Issue.5 , pp. 539-545
    • Struthers, A.D.1
  • 11
    • 11444267671 scopus 로고    scopus 로고
    • Effects of eplerenone, a selective aldosterone blocker, on the progression of left ventricular dysfunction and remodeling in rats with dilated cardiomyopathy
    • DOI 10.1159/000081267
    • M.I. Wahed, K. Watanabe, M. Ma Effects of eplerenone, a selective aldosterone blocker, on the progression of left ventricular dysfunction and remodeling in rats with dilated cardiomyopathy Pharmacology 73 2005 81 88 (Pubitemid 40082318)
    • (2005) Pharmacology , vol.73 , Issue.2 , pp. 81-88
    • Wahed, M.I.I.1    Watanabe, K.2    Ma, M.3    Yamaguchi, K.4    Takahashi, T.5    Tachikawa, H.6    Kodama, M.7    Aizawa, Y.8
  • 12
    • 34249794560 scopus 로고    scopus 로고
    • Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: Involvement of tenascin-C induced by aldosterone-mediated inflammation
    • DOI 10.1097/FJC.0b013e318033dfd4, PII 0000534420070500000002
    • T. Nishioka, M. Suzuki, K. Onishi Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation J Cardiovasc Pharmacol 49 2007 261 268 (Pubitemid 46855118)
    • (2007) Journal of Cardiovascular Pharmacology , vol.49 , Issue.5 , pp. 261-268
    • Nishioka, T.1    Suzuki, M.2    Onishi, K.3    Takakura, N.4    Inada, H.5    Yoshida, T.6    Hiroe, M.7    Imanaka-Yoshida, K.8
  • 13
    • 0035312341 scopus 로고    scopus 로고
    • Effect of spironolactone on plasma brain natriuretic peptide and left ventricular remodeling in patients with congestive heart failure
    • T. Tsutamoto, A. Wada, K. Maeda Effect of spironolactone on plasma brain natriuretic peptide and left ventricular remodeling in patients with congestive heart failure J Am Coll Cardiol 37 2001 1228 1233
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1228-1233
    • Tsutamoto, T.1    Wada, A.2    Maeda, K.3
  • 14
    • 0027227646 scopus 로고
    • Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism
    • DOI 10.1006/jmcc.1993.1066
    • C.G. Brilla, L.S. Matsubara, K.T. Weber Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism J Mol Cell Cardiol 25 1993 563 575 (Pubitemid 23208145)
    • (1993) Journal of Molecular and Cellular Cardiology , vol.25 , Issue.5 , pp. 563-575
    • Brilla, C.G.1    Matsubara, L.S.2    Weber, K.T.3
  • 15
    • 3543099842 scopus 로고    scopus 로고
    • Effect of aldosterone antagonism on myocardial dysfunction in hypertensive patients with diastolic heart failure
    • DOI 10.1161/01.CIR.0000138680.89536.A9
    • P.M. Mottram, B. Haluska, R. Leano, D. Cowley, M. Stowasser, T.H. Marwick Effect of aldosterone antagonism on myocardial dysfunction in hypertensive patients with diastolic heart failure Circulation 110 2004 558 565 (Pubitemid 39031173)
    • (2004) Circulation , vol.110 , Issue.5 , pp. 558-565
    • Mottram, P.M.1    Haluska, B.2    Leano, R.3    Cowley, D.4    Stowasser, M.5    Marwick, T.H.6
  • 16
    • 46049084581 scopus 로고    scopus 로고
    • Spironolactone alleviates late cardiac remodeling after left ventricular restoration surgery
    • M. Tsukashita, A. Marui, T. Nishina Spironolactone alleviates late cardiac remodeling after left ventricular restoration surgery J Thorac Cardiovasc Surg 136 2008 58 64
    • (2008) J Thorac Cardiovasc Surg , vol.136 , pp. 58-64
    • Tsukashita, M.1    Marui, A.2    Nishina, T.3
  • 18
    • 0038526268 scopus 로고    scopus 로고
    • Immediate administration of mineralocorticoid receptor antagonist spironolactone prevents post-infarct left ventricular remodeling associated with suppression of a marker of myocardial collagen synthesis in patients with first anterior acute myocardial infarction
    • DOI 10.1161/01.CIR.0000068340.96506.0F
    • M. Hayashi, T. Tsutamoto, A. Wada Immediate administration of mineralocorticoid receptor antagonist spironolactone prevents post-infarct left ventricular remodeling associated with suppression of a marker of myocardial collagen synthesis in patients with first anterior acute myocardial infarction Circulation 107 2003 2559 2565 (Pubitemid 36628936)
    • (2003) Circulation , vol.107 , Issue.20 , pp. 2559-2565
    • Hayashi, M.1    Tsutamoto, T.2    Wada, A.3    Tsutsui, T.4    Ishii, C.5    Ohno, K.6    Fujii, M.7    Taniguchi, A.8    Hamatani, T.9    Nozato, Y.10    Kataoka, K.11    Morigami, N.12    Ohnishi, M.13    Kinoshita, M.14    Horie, M.15
  • 19
    • 59649126215 scopus 로고    scopus 로고
    • Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling
    • S.W. van den Borne, S. Isobe, H.R. Zandbergen Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling J Am Coll Cardiol Img 2 2009 187 198
    • (2009) J Am Coll Cardiol Img , vol.2 , pp. 187-198
    • Van Den Borne, S.W.1    Isobe, S.2    Zandbergen, H.R.3
  • 20
    • 0034727695 scopus 로고    scopus 로고
    • Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: Insights from the Randomized Aldactone Evaluation Study (RALES) Rales Investigators
    • F. Zannad, F. Alla, B. Dousset, A. Perez, B. Pitt Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: insights from the Randomized Aldactone Evaluation Study (RALES) Rales Investigators Circulation 102 2000 2700 2706
    • (2000) Circulation , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3    Perez, A.4    Pitt, B.5
  • 21
    • 66549112420 scopus 로고    scopus 로고
    • Extracellular cardiac matrix biomarkers in patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure: Insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) study
    • W. Iraqi, P. Rossignol, M. Angioi Extracellular cardiac matrix biomarkers in patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure: insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) study Circulation 119 2009 2471 2479
    • (2009) Circulation , vol.119 , pp. 2471-2479
    • Iraqi, W.1    Rossignol, P.2    Angioi, M.3
  • 22
    • 78650399880 scopus 로고    scopus 로고
    • Eplerenone in patients with systolic heart failure and mild symptoms
    • EMPHASIS-HF Study Group
    • F. Zannad, J.J. McMurray, H. Krum EMPHASIS-HF Study Group Eplerenone in patients with systolic heart failure and mild symptoms N Engl J Med 364 2011 11 21
    • (2011) N Engl J Med , vol.364 , pp. 11-21
    • Zannad, F.1    McMurray, J.J.2    Krum, H.3
  • 23
    • 0343554659 scopus 로고    scopus 로고
    • Monitoring fibrillar collagen turnover in hypertensive heart disease
    • DOI 10.1016/S0008-6363(97)00072-2, PII S0008636397000722
    • J. Díez, C. Laviades Monitoring fibrillar collagen turnover in hypertensive heart disease Cardiovasc Res 35 1997 202 205 (Pubitemid 27372031)
    • (1997) Cardiovascular Research , vol.35 , Issue.2 , pp. 202-205
    • Diez, J.1    Laviades, C.2
  • 24
    • 0028911936 scopus 로고
    • Increased serum concentrations of procollagen peptides in essential hypertension Relation to cardiac alterations
    • J. Díez, C. Laviades, G. Mayor, M.J. Gil, I. Monreal Increased serum concentrations of procollagen peptides in essential hypertension Relation to cardiac alterations Circulation 91 1995 1450 1456
    • (1995) Circulation , vol.91 , pp. 1450-1456
    • Díez, J.1    Laviades, C.2    Mayor, G.3    Gil, M.J.4    Monreal, I.5
  • 25
    • 0035902457 scopus 로고    scopus 로고
    • Usefulness of serum carboxy-terminal propeptide of procollagen type I in assessment of the cardioreparative ability of antihypertensive treatment in hypertensive patients
    • B. López, R. Querejeta, N. Varo Usefulness of serum carboxy-terminal propeptide of procollagen type I in assessment of the cardioreparative ability of antihypertensive treatment in hypertensive patients Circulation 104 2001 286 291 (Pubitemid 32666949)
    • (2001) Circulation , vol.104 , Issue.3 , pp. 286-291
    • Lopez, B.1    Querejeta, R.2    Varo, N.3    Gonzalez, A.4    Larman, M.5    Martinez Ubago, J.L.6    Diez, J.7
  • 26
    • 77950679021 scopus 로고    scopus 로고
    • CONSORT 2010 statement: Updated guidelines for reporting parallel group randomized trials
    • CONSORT Group
    • K.F. Schulz, D.G. Altman, D. Moher CONSORT Group CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials PLoS Med 7 2010 e1000251
    • (2010) PLoS Med , vol.7 , pp. 1000251
    • Schulz, K.F.1    Altman, D.G.2    Moher, D.3
  • 28
  • 29
    • 0022588019 scopus 로고
    • Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings
    • DOI 10.1016/0002-9149(86)90771-X
    • R.B. Devereux, D.R. Alonso, E.M. Lutas Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings Am J Cardiol 57 1986 450 458 (Pubitemid 16119719)
    • (1986) American Journal of Cardiology , vol.57 , Issue.6 , pp. 450-458
    • Devereux, R.B.1    Alonso, D.R.2    Lutas, E.M.3
  • 31
    • 0242552745 scopus 로고    scopus 로고
    • Ventricular dysfunction in early diabetic heart disease: Detection, mechanisms and significance
    • DOI 10.1042/CS20030211
    • G.F. Watts, T.H. Marwick Ventricular dysfunction in early diabetic heart disease: detection, mechanisms and significance Clin Sci (Lond) 105 2003 537 540 (Pubitemid 37421645)
    • (2003) Clinical Science , vol.105 , Issue.5 , pp. 537-540
    • Watts, G.F.1    Marwick, T.H.2
  • 32
    • 0034044806 scopus 로고    scopus 로고
    • Renin-angiotensin-aldosterone system and myocardial fibrosis
    • C.G. Brilla Renin-angiotensin-aldosterone system and myocardial fibrosis Cardiovasc Res 47 2000 1 3
    • (2000) Cardiovasc Res , vol.47 , pp. 1-3
    • Brilla, C.G.1
  • 33
    • 0033779229 scopus 로고    scopus 로고
    • Transforming growth factor beta in hypertensives with cardiorenal damage
    • C. Laviades, N. Varo, J. Díez Transforming growth factor beta in hypertensives with cardiorenal damage Hypertension 36 2000 517 522
    • (2000) Hypertension , vol.36 , pp. 517-522
    • Laviades, C.1    Varo, N.2    Díez, J.3
  • 34
    • 0028840698 scopus 로고
    • Biological determinants of aldosterone-induced cardiac fibrosis in rats
    • V. Robert, J.S. Silvestre, D. Charlemagne Biological determinants of aldosterone-induced cardiac fibrosis in rats Hypertension 26 1995 971 978
    • (1995) Hypertension , vol.26 , pp. 971-978
    • Robert, V.1    Silvestre, J.S.2    Charlemagne, D.3
  • 35
    • 0028360454 scopus 로고
    • Increased cardiac types I and III collagen mRNAs in aldosterone-salt hypertension
    • V. Robert, N. Van Thiem, S.L. Cheav, C. Mouas, B. Swynghedauw, C. Delcayre Increased cardiac types I and III collagen mRNAs in aldosterone-salt hypertension Hypertension 24 1994 30 36 (Pubitemid 24195401)
    • (1994) Hypertension , vol.24 , Issue.1 , pp. 30-36
    • Robert, V.1    Van Thiem, N.2    Cheav, S.L.3    Mouas, C.4    Swynghedauw, B.5    Delcayre, C.6


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