Field Evaluation of a Prototype Paper-Based Point-of-Care Fingerstick Transaminase Test

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Pollock, Nira R ^a,b   McGray, Sarah ^c   Colby, Donn J ^a,d   Noubary, Farzad ^e   Nguyen, Huyen ^d,f   Nguyen, The Anh ^d   Khormaee, Sariah ^d   Jain, Sidhartha ^g   Hawkins, Kenneth ^c   Kumar, Shailendra ^g   Rolland, Jason P ^g   Beattie, Patrick D ^g   Chau, Nguyen V ^h   Quang, Vo M ^h   Barfield, Cori ^c   Tietje, Kathy ^c   Steele, Matt ^c   Weigl, Bernhard H ^c  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c PATH   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e TUFTS UNIVERSITY   (United States)

^f Center for Applied Research on Men and Health   (Viet Nam)

^g Diagnostics for All   (United States)

^h UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIRETROVIRUS AGENT; SILICON DIOXIDE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANALYTICAL EQUIPMENT; ANALYTICAL PARAMETERS; ARTICLE; CAPILLARY TUBE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; ENZYME ANALYSIS; EQUIPMENT FAILURE; FEASIBILITY STUDY; FEMALE; FIELD STUDY; GOLD STANDARD; HEMOLYSIS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTER OPERATOR VARIABILITY; LOT VARIABILITY; MAJOR CLINICAL STUDY; MALE; MICROFLUIDIC FINGERSTICK TEST; OUTPATIENT; PAPER BASED MICROFLUIDIC DEVICE; POINT OF CARE TESTING; PROCESS OPTIMIZATION; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SCALPEL; TOXIC HEPATITIS; VALIDITY; VEIN PUNCTURE; VIET NAM;

ALANINE TRANSAMINASE; BLOOD CHEMICAL ANALYSIS; DEVELOPING COUNTRIES; DRUG MONITORING; DRUG-INDUCED LIVER INJURY; HUMANS; LIVER FUNCTION TESTS; MICROFLUIDICS; OBSERVER VARIATION; PAPER; POINT-OF-CARE SYSTEMS; VIETNAM;

EID: 84884743864     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075616     Document Type: Article

References (37)

1. Saukkonen JJ, Cohn DL, Jasmer RM, Schenker S, Jereb JA, et al. (2006) An official ATS statement: hepatotoxicity of antituberculosis therapy. Am J Respir Crit Care Med 174: 935-952.
2. Panel on Antiretroviral Guidelines for Adults and Adolescents (2012) Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services: 1-161. Available: http://www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf. Accessed 2012 Dec 28.
3. Pollock NR, Rolland JP, Kumar S, Beattie PD, Jain S, et al. (2012) A paper-based multiplexed transaminase test for low-cost, point-of-care liver function testing. Sci Transl Med 4: 152ra129.
4. Martinez AW, Phillips ST, Whitesides GM, Carrilho E, (2010) Diagnostics for the developing world: microfluidic paper-based analytical devices. Anal Chem 82: 3-10.
5. Martinez AW, Phillips ST, Carrilho E, Thomas SW, (2008) Simple telemedicine for developing regions: camera phones and paper-based microfluidic devices for real-time, off-site diagnosis. Anal Chem 80: 3699-3707.
6. Martinez AW, Phillips ST, Butte MJ, Whitesides GM, (2007) Patterned paper as a platform for inexpensive, low-volume, portable bioassays. Angew Chem Int Ed Engl 46: 1318-1320.
7. Martinez AW, Phillips ST, Whitesides GM, (2008) Three-dimensional microfluidic devices fabricated in layered paper and tape. Proc Natl Acad Sci U S A 105: 19606-19611.
8. Cheng CM, Martinez AW, Gong J, Mace CR, Phillips ST, et al. (2010) Paper-based ELISA. Angew Chem Int Ed Engl 49: 4771-4774.
9. Nie Z, Deiss F, Liu X, Akbulut O, Whitesides GM, (2010) Integration of paper-based microfluidic devices with commercial electrochemical readers. Lab Chip 10: 3163-3169.
10. Osborn JL, Lutz B, Fu E, Kauffman P, Stevens DY, et al. (2010) Microfluidics without pumps: reinventing the T-sensor and H-filter in paper networks. Lab Chip 10: 2659-2665.
11. Fu E, Lutz B, Kauffman P, Yager P, (2010) Controlled reagent transport in disposable 2D paper networks. Lab Chip 10: 918-920.
12. Lutz BR, Trinh P, Ball C, Fu E, Yager P, (2011) Two-dimensional paper networks: programmable fluidic disconnects for multi-step processes in shaped paper. Lab Chip 11: 4274-4278.
13. Fu E, Kauffman P, Lutz B, Yager P, (2010) Chemical signal amplification in two-dimensional paper networks. Sens Actuators B Chem 149: 325-328.
14. Khan MS, Thouas G, Shen W, Whyte G, Garnier G, (2010) Paper diagnostic for instantaneous blood typing. Anal Chem 82: 4158-4164.
15. Li X, Tian J, Garnier G, Shen W, (2010) Fabrication of paper-based microfluidic sensors by printing. Colloids Surf B Biointerfaces 76: 564-570.
16. Dungchai W, Chailapakul O, Henry CS, (2010) Use of multiple colorimetric indicators for paper-based microfluidic devices. Anal Chim Acta 674: 227-233.
17. Fenton EM, Mascarenas MR, Lopez GP, Sibbett SS, (2009) Multiplex lateral-flow test strips fabricated by two-dimensional shaping. ACS Appl Mater Interfaces 1: 124-129.
18. Vella SJ, Beattie P, Cademartiri R, Laromaine A, Martinez AW, et al. (2012) Measuring markers of liver function using a micropatterned paper device designed for blood from a fingerstick. Anal Chem 84: 2883-2891.
19. Li X, Ballerini DR, Shen W, (2012) A perspective on paper-based microfluidics: Current status and future trends. Biomicrofluidics 6: 11301-1130113.
20. Delaney JL, Hogan CF, Tian J, Shen W, (2011) Electrogenerated chemiluminescence detection in paper-based microfluidic sensors. Anal Chem 83: 1300-1306.
21. Chin CD, Linder V, Sia SK, (2012) Commercialization of microfluidic point-of-care diagnostic devices. Lab Chip 12: 2118-2134.
22. Vietnam Ministry of Health (2009) Guidelines on the Diagnosis and Treatment of HIV/AIDS. Hanoi.
23. McKoy JM, Bennett CL, Scheetz MH, Differding V, Chandler KL, et al. (2009) Hepatotoxicity associated with long- versus short-course HIV-prophylactic nevirapine use: a systematic review and meta-analysis from the Research on Adverse Drug events And Reports (RADAR) project. Drug Saf 32: 147-158.
24. Martinez E, Blanco JL, Arnaiz JA, Perez-Cuevas JB, Mocroft A, et al. (2001) Hepatotoxicity in HIV-1-infected patients receiving nevirapine-containing antiretroviral therapy. AIDS 15: 1261-1268.
25. Tostmann A, Boeree MJ, Aarnoutse RE, de Lange WC, van der Ven AJ, et al. (2008) Antituberculosis drug-induced hepatotoxicity: concise up-to-date review. J Gastroenterol Hepatol 23: 192-202.
26. Shipton LK, Wester CW, Stock S, Ndwapi N, Gaolathe T, et al. (2009) Safety and efficacy of nevirapine- and efavirenz-based antiretroviral treatment in adults treated for TB-HIV co-infection in Botswana. Int J Tuberc Lung Dis 13: 360-366.
27. Hoffmann CJ, Charalambous S, Thio CL, Martin DJ, Pemba L, et al. (2007) Hepatotoxicity in an African antiretroviral therapy cohort: the effect of tuberculosis and hepatitis B. AIDS. 21: 1301-1308.
28. Lee WM, (1995) Drug-induced hepatotoxicity. N Engl J Med 333: 1118-1127.
29. Grant LM, Rockey DC, (2012) Drug-induced liver injury. Curr Opin Gastroenterol 28: 198-202.
30. Davern TJ, (2012) Drug-induced liver disease. Clin Liver Dis 16: 231-245.
31. Centers for Disease Control and Prevention (2010) Severe isoniazid-associated liver injuries among persons being treated for latent tuberculosis infection-United States, 2004-2008. MMWR Morb Mortal Wkly Rep 59: 224-229.
32. World Health Organization (2010) Antiretroviral therapy for HIV infection in adults and adolescents in resource-limited settings: recommendations for a public health approach, 2010 revision. Geneva, Switzerland.
33. AIDS Clinical Trials Group (1996)Table of grading severity of adult adverse experiences. Rockville, MD: Division of AIDS, National Institute of Allergy and Infectious Diseases.
34. Meintjes G, Maartens G, Boulle A, Conradie F, Goemaere E, et al. (2012) Guidelines for antiretroviral therapy in adults. S Afr J HIV Med 13: 114-133.
35. National AIDS Control Organisation (2007) Antiretroviral therapy guidelines for HIV-infected adults and adolescents including post-exposure prophylaxis. India Ministry of Health and Family Welfare.
36. World Health Organization (2009) Treatment of tuberculosis guidelines 4th edition. Geneva, Switzerland: World Health Organization; 2009.
37. Shieh FK, Snyder G, Horsburgh CR, Bernardo J, Murphy C, et al. (2006) Predicting non-completion of treatment for latent tuberculous infection: a prospective survey. Am J Respir Crit Care Med 174: 717-721.