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Volumn 80, Issue 10, 2008, Pages 3699-3707

Simple telemedicine for developing regions: Camera phones and paper-based microfluidic devices for real-time, off-site diagnosis

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSIS; MOBILE PHONES; REAL TIME CONTROL; TELEMEDICINE;

EID: 43949138608     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac800112r     Document Type: Article
Times cited : (1275)

References (63)
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    • The artificial urine solution contained 1.1 mM lactic acid, 2.0 mM citric acid, 25 mM sodium bicarbonate, 170 mM urea, 2.5 mM calcium chloride, 90 mM sodium chloride, 2.0 mM magnesium sulfate, 10 mM sodium sulfate, 7.0 mM potassium dihydrogen phosphate, 7.0 mM dipotassium hydrogen phosphate, and 25 mM ammonium chloride all mixed in Millipore-purified water. The pH of the solution was adjusted to 6.0 by addition of 1.0 M hydrochloric acid.
    • The artificial urine solution contained 1.1 mM lactic acid, 2.0 mM citric acid, 25 mM sodium bicarbonate, 170 mM urea, 2.5 mM calcium chloride, 90 mM sodium chloride, 2.0 mM magnesium sulfate, 10 mM sodium sulfate, 7.0 mM potassium dihydrogen phosphate, 7.0 mM dipotassium hydrogen phosphate, and 25 mM ammonium chloride all mixed in Millipore-purified water. The pH of the solution was adjusted to 6.0 by addition of 1.0 M hydrochloric acid.
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    • Other fluids that should be compatible with the paper-based platform include tears, saliva, and sweat, and (less conveniently) vaginal fluids, wound exudates, nasal mucus, feces, plasma, blood, spinal fluid, amniotic fluid, nipple aspirate, and diarrhea fluid
    • Other fluids that should be compatible with the paper-based platform include tears, saliva, and sweat, and (less conveniently) vaginal fluids, wound exudates, nasal mucus, feces, plasma, blood, spinal fluid, amniotic fluid, nipple aspirate, and diarrhea fluid.
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    • 2 per minute at pH 5.1 and 35°C.
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    • One purpurogallin unit will form 1.0 mg of purpurogallin from pyrogallol in 20 s at pH 6.0 and 20°C.
    • One purpurogallin unit will form 1.0 mg of purpurogallin from pyrogallol in 20 s at pH 6.0 and 20°C.
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    • Other laboratories have used similar scanometric detection methods for quantifying bioassays run on other platforms
    • Other laboratories have used similar "scanometric" detection methods for quantifying bioassays run on other platforms.
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    • We repeated the experiment for pollen using a sample of artificial urine with no BSA, and we measured 34 ± 10 μM of protein. This result suggests that some of the protein from the pollen dissolved into the sample of artificial urine and resulted in the elevated measurement.
    • We repeated the experiment for pollen using a sample of artificial urine with no BSA, and we measured 34 ± 10 μM of protein. This result suggests that some of the protein from the pollen dissolved into the sample of artificial urine and resulted in the elevated measurement.


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