Safflor yellow B suppresses angiotensin II-mediated human umbilical vein cell injury via regulation of Bcl-2/p22phox expression

Toxicology and Applied Pharmacology

Volumn 273, Issue 1, 2013, Pages 59-67

  Wang, Chaoyun ^a,b   He, Yanhao ^a,b   Yang, Ming ^a   Sun, Hongliu ^a   Zhang, Shuping ^a   Wang, Chunhua ^a  

^a BINZHOU MEDICAL UNIVERSITY   (China)

^b MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Angiotensin II; Bcl 2; Mitochondrial membrane potential; NADPH oxidase; P22phox; Safflor yellow B

Indexed keywords

ANGIOTENSIN II; ANTIOXIDANT; FLAVONOID; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P22; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SAFFLOR YELLOW B; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL FUNCTION; CELL VIABILITY; CONTROLLED STUDY; DEPOLARIZATION; ENZYME ACTIVITY; HOMEOSTASIS; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PROTEIN EXPRESSION; UMBILICAL VEIN ENDOTHELIAL CELL;

ANGIOTENSIN II; BCL-2; MITOCHONDRIAL MEMBRANE POTENTIAL; NADPH OXIDASE; P22(PHOX); SAFFLOR YELLOW B;

ANGIOTENSIN II; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL SURVIVAL; CELLS, CULTURED; CHALCONE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MITOCHONDRIA; NADPH OXIDASE; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; RECEPTOR, ANGIOTENSIN, TYPE 1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UMBILICAL VEINS; UP-REGULATION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84884712647     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.08.018     Document Type: Article

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