메뉴 건너뛰기




Volumn 46, Issue 5, 2013, Pages 509-515

Could plant lectins become promising anti-tumour drugs for causing autophagic cell death?

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BECLIN 1; CONCANAVALIN A; K RAS PROTEIN; PLANT LECTIN; POLYGONATUM CYRTONEMA LECTIN; PROTEIN BNIP3; PROTEIN KINASE B; RAF PROTEIN; UNCLASSIFIED DRUG; VISCUM ALBUM LECTIN;

EID: 84884703479     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/cpr.12054     Document Type: Article
Times cited : (54)

References (45)
  • 2
    • 16644383558 scopus 로고    scopus 로고
    • The identification of inducible cytoplasmic/nuclear carbohydrate-binding proteins urges to develop novel concepts about the role of plant lectins
    • Van Damme EJ, Lannoo N, Fouquaert E, Peumans WJ (2004) The identification of inducible cytoplasmic/nuclear carbohydrate-binding proteins urges to develop novel concepts about the role of plant lectins. Glycoconj. J. 20, 449-460.
    • (2004) Glycoconj. J. , vol.20 , pp. 449-460
    • Van Damme, E.J.1    Lannoo, N.2    Fouquaert, E.3    Peumans, W.J.4
  • 3
    • 72049120117 scopus 로고    scopus 로고
    • Plant lectins: potential antineoplastic drugs from bench to clinic
    • Liu B, Bian HJ, Bao JK (2010) Plant lectins: potential antineoplastic drugs from bench to clinic. Cancer Lett. 287, 1-12.
    • (2010) Cancer Lett. , vol.287 , pp. 1-12
    • Liu, B.1    Bian, H.J.2    Bao, J.K.3
  • 4
    • 0028872958 scopus 로고
    • Use of lectins as diagnostic and therapeutic tools for cancer
    • Mody R, Joshi S, Chaney W (1995) Use of lectins as diagnostic and therapeutic tools for cancer. J. Pharmacol. Toxicol. Methods 33, 1-10.
    • (1995) J. Pharmacol. Toxicol. Methods , vol.33 , pp. 1-10
    • Mody, R.1    Joshi, S.2    Chaney, W.3
  • 5
    • 84865574556 scopus 로고    scopus 로고
    • Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents
    • Zhang X, Chen LX, Ouyang L, Cheng Y, Liu B (2012) Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents. Cell Prolif. 454, 466-476.
    • (2012) Cell Prolif. , vol.454 , pp. 466-476
    • Zhang, X.1    Chen, L.X.2    Ouyang, L.3    Cheng, Y.4    Liu, B.5
  • 6
    • 79960925702 scopus 로고    scopus 로고
    • Core signaling pathways of survival/death in autophagy-related cancer networks
    • Wang SY, Yu QJ, Zhang RD, Liu B (2011) Core signaling pathways of survival/death in autophagy-related cancer networks. Int. J. Biochem. Cell Biol. 43, 1263-1266.
    • (2011) Int. J. Biochem. Cell Biol. , vol.43 , pp. 1263-1266
    • Wang, S.Y.1    Yu, Q.J.2    Zhang, R.D.3    Liu, B.4
  • 7
    • 77956363593 scopus 로고    scopus 로고
    • Autophagic pathways as new targets for cancer drug development
    • Liu B, Cheng Y, Liu Q, Bao JK, Yang JM (2010) Autophagic pathways as new targets for cancer drug development. Acta Pharmacol. Sin. 31, 1154-1164.
    • (2010) Acta Pharmacol. Sin. , vol.31 , pp. 1154-1164
    • Liu, B.1    Cheng, Y.2    Liu, Q.3    Bao, J.K.4    Yang, J.M.5
  • 10
    • 80054843050 scopus 로고    scopus 로고
    • Concanavalin A: a potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics
    • Li WW, Yu JY, Xu HL, Bao JK (2011) Concanavalin A: a potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics. Biochem. Biophys. Res. Commun. 414, 282-286.
    • (2011) Biochem. Biophys. Res. Commun. , vol.414 , pp. 282-286
    • Li, W.W.1    Yu, J.Y.2    Xu, H.L.3    Bao, J.K.4
  • 11
    • 61649114199 scopus 로고    scopus 로고
    • Molecular mechanisms of Polygonatum cyrtonema lectin-induced apoptosis and autophagy in cancer cells
    • Liu B, Cheng Y, Bian HJ, Bao JK (2009) Molecular mechanisms of Polygonatum cyrtonema lectin-induced apoptosis and autophagy in cancer cells. Autophagy 5, 253-255.
    • (2009) Autophagy , vol.5 , pp. 253-255
    • Liu, B.1    Cheng, Y.2    Bian, H.J.3    Bao, J.K.4
  • 12
    • 67349118806 scopus 로고    scopus 로고
    • Bioinformatics analyses of the mannose-binding lectins from Polygonatum cyrtonema, Ophiopogon japonicus and Liparis noversa with anti-proliferative and apoptosis-inducing activities
    • Liu B, Peng H, Yao Q, Li J, Van Damme E, Balzarini J et al. (2009) Bioinformatics analyses of the mannose-binding lectins from Polygonatum cyrtonema, Ophiopogon japonicus and Liparis noversa with anti-proliferative and apoptosis-inducing activities. Phytomedicine 16, 601-608.
    • (2009) Phytomedicine , vol.16 , pp. 601-608
    • Liu, B.1    Peng, H.2    Yao, Q.3    Li, J.4    Van Damme, E.5    Balzarini, J.6
  • 13
    • 34047255890 scopus 로고    scopus 로고
    • Lectins: carbohydrate-specific reagents and biological recognition molecules
    • Sharon N (2007) Lectins: carbohydrate-specific reagents and biological recognition molecules. J. Biol. Chem. 282, 2753-2764.
    • (2007) J. Biol. Chem. , vol.282 , pp. 2753-2764
    • Sharon, N.1
  • 14
    • 79953027945 scopus 로고    scopus 로고
    • Polygonatum cyrtonema lectin: a potential antineoplastic drug targeting programmed cell death pathways
    • Wang SY, Yu QJ, Bao JK, Liu B (2011) Polygonatum cyrtonema lectin: a potential antineoplastic drug targeting programmed cell death pathways. Biochem. Biophys. Res. Commun. 406, 497-500.
    • (2011) Biochem. Biophys. Res. Commun. , vol.406 , pp. 497-500
    • Wang, S.Y.1    Yu, Q.J.2    Bao, J.K.3    Liu, B.4
  • 15
    • 77955089694 scopus 로고    scopus 로고
    • Crystal structures of a novel anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua with unique ligand-binding property and super-structure
    • Ding J, Bao J, Zhu D, Zhang Y, Wang DC (2010) Crystal structures of a novel anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua with unique ligand-binding property and super-structure. J. Struct. Biol. 171, 309-317.
    • (2010) J. Struct. Biol. , vol.171 , pp. 309-317
    • Ding, J.1    Bao, J.2    Zhu, D.3    Zhang, Y.4    Wang, D.C.5
  • 16
    • 84876221574 scopus 로고    scopus 로고
    • Triterpenoids amplify anti-tumoral effects of mistletoe extracts on murine b16. f10 melanoma in vivo
    • Strüh CM, Jäger S, Kersten A, Schempp CM, Scheffler A, Martin SF (2013) Triterpenoids amplify anti-tumoral effects of mistletoe extracts on murine b16. f10 melanoma in vivo. PLoS One 8, e62168.
    • (2013) PLoS One , vol.8
    • Strüh, C.M.1    Jäger, S.2    Kersten, A.3    Schempp, C.M.4    Scheffler, A.5    Martin, S.F.6
  • 17
    • 43049176801 scopus 로고    scopus 로고
    • Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro
    • Seifert G, Jesse P, Laengler A, Reindl T, Lüth M, Lobitz S et al. (2008) Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro. Cancer Lett. 264, 218-228.
    • (2008) Cancer Lett. , vol.264 , pp. 218-228
    • Seifert, G.1    Jesse, P.2    Laengler, A.3    Reindl, T.4    Lüth, M.5    Lobitz, S.6
  • 18
    • 48249135681 scopus 로고    scopus 로고
    • Mistletoe lectins: carbohydrate-specific apoptosis inducers and immunomodulators
    • Hoessli DC, Ahmad I (2008) Mistletoe lectins: carbohydrate-specific apoptosis inducers and immunomodulators. Curr. Org. Chem. 12, 918-925.
    • (2008) Curr. Org. Chem. , vol.12 , pp. 918-925
    • Hoessli, D.C.1    Ahmad, I.2
  • 19
    • 0035149593 scopus 로고    scopus 로고
    • Combined cytotoxic action of Viscum album agglutinin-1 and anticancer agents against human A549 lung cancer cells
    • Siegle I, Fritz P, McClellan M, Gutzeit S, Mürdter TE (2001) Combined cytotoxic action of Viscum album agglutinin-1 and anticancer agents against human A549 lung cancer cells. Anticancer Res. 21, 2687-2691.
    • (2001) Anticancer Res. , vol.21 , pp. 2687-2691
    • Siegle, I.1    Fritz, P.2    McClellan, M.3    Gutzeit, S.4    Mürdter, T.E.5
  • 20
    • 38449085362 scopus 로고    scopus 로고
    • Uses of plant lectins in bioscience and biomedicine
    • Pusztai A, Bardocz S, Ewen SW (2008) Uses of plant lectins in bioscience and biomedicine. Front. Biosci. 13, 1130-1140.
    • (2008) Front. Biosci. , vol.13 , pp. 1130-1140
    • Pusztai, A.1    Bardocz, S.2    Ewen, S.W.3
  • 21
    • 78649634631 scopus 로고    scopus 로고
    • Targeting apoptotic and autophagic pathways for cancer therapeutics
    • Liu JJ, Lin M, Yu JY, Liu B, Bao JK (2011) Targeting apoptotic and autophagic pathways for cancer therapeutics. Cancer Lett. 300, 105-114.
    • (2011) Cancer Lett. , vol.300 , pp. 105-114
    • Liu, J.J.1    Lin, M.2    Yu, J.Y.3    Liu, B.4    Bao, J.K.5
  • 22
    • 58849153349 scopus 로고    scopus 로고
    • Antiproliferative activity and apoptosis-inducing mechanism of Concanavalin A on human melanoma A375 cells
    • Liu B, Li CY, Bian HJ, Min MW, Chen LF, Bao JK (2009) Antiproliferative activity and apoptosis-inducing mechanism of Concanavalin A on human melanoma A375 cells. Arch. Biochem. Biophys. 482, 1-6.
    • (2009) Arch. Biochem. Biophys. , vol.482 , pp. 1-6
    • Liu, B.1    Li, C.Y.2    Bian, H.J.3    Min, M.W.4    Chen, L.F.5    Bao, J.K.6
  • 23
    • 77952890932 scopus 로고    scopus 로고
    • In silico and experimental studies of Concanavalin A: insights into its antiproliferative activity and apoptotic mechanism
    • Liu ZY, Li XF, Ding XP, Yang Y (2010) In silico and experimental studies of Concanavalin A: insights into its antiproliferative activity and apoptotic mechanism. Appl. Biochem. Biotechnol. 162, 134-145.
    • (2010) Appl. Biochem. Biotechnol. , vol.162 , pp. 134-145
    • Liu, Z.Y.1    Li, X.F.2    Ding, X.P.3    Yang, Y.4
  • 24
    • 77249092175 scopus 로고    scopus 로고
    • The lectin Concanavalin-A signals MT1-MMP catalytic independent induction of COX-2 through an IKKγ/NF-κB-dependent pathway
    • Sina A, Proulx-Bonneau S, Roy A, Poliquin L, Cao J, Annabi B (2010) The lectin Concanavalin-A signals MT1-MMP catalytic independent induction of COX-2 through an IKKγ/NF-κB-dependent pathway. J. Cell Commun. Signal. 4, 31-38.
    • (2010) J. Cell Commun. Signal. , vol.4 , pp. 31-38
    • Sina, A.1    Proulx-Bonneau, S.2    Roy, A.3    Poliquin, L.4    Cao, J.5    Annabi, B.6
  • 25
    • 34250826027 scopus 로고    scopus 로고
    • A novel role for p73 in the regulation of Akt-Foxo1a-Bim signaling and apoptosis induced by the plant lectin, Concanavalin A
    • Ruhul Amin AR, Paul RK, Thakur VS, Agarwal ML (2007) A novel role for p73 in the regulation of Akt-Foxo1a-Bim signaling and apoptosis induced by the plant lectin, Concanavalin A. Cancer Res. 67, 5617-5621.
    • (2007) Cancer Res. , vol.67 , pp. 5617-5621
    • Ruhul Amin, A.R.1    Paul, R.K.2    Thakur, V.S.3    Agarwal, M.L.4
  • 26
    • 58749105634 scopus 로고    scopus 로고
    • Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway
    • Liu B, Cheng Y, Zhang B, Bian HJ, Bao JK (2009) Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway. Cancer Lett. 275, 54-60.
    • (2009) Cancer Lett. , vol.275 , pp. 54-60
    • Liu, B.1    Cheng, Y.2    Zhang, B.3    Bian, H.J.4    Bao, J.K.5
  • 27
    • 78650250800 scopus 로고    scopus 로고
    • Polygonatum cyrtonema lectin induces murine fibrosarcoma L929 cell apoptosis and autophagy via blocking Ras-Raf and PI3K-Akt signaling pathways
    • Liu B, Wu JM, Li J, Liu JJ, Li WW, Li CY et al. (2010) Polygonatum cyrtonema lectin induces murine fibrosarcoma L929 cell apoptosis and autophagy via blocking Ras-Raf and PI3K-Akt signaling pathways. Biochimie 92, 1934-1938.
    • (2010) Biochimie , vol.92 , pp. 1934-1938
    • Liu, B.1    Wu, J.M.2    Li, J.3    Liu, J.J.4    Li, W.W.5    Li, C.Y.6
  • 28
    • 0036480161 scopus 로고    scopus 로고
    • Korean mistletoe lectin-induced apoptosis in hepatocarcinoma cells is associated with inhibition of telomerase via mitochondrial controlled pathway independent of p53
    • Lyu SY, Choi SH, Park WB (2002) Korean mistletoe lectin-induced apoptosis in hepatocarcinoma cells is associated with inhibition of telomerase via mitochondrial controlled pathway independent of p53. Arch. Pharm. Res. 25, 93-101.
    • (2002) Arch. Pharm. Res. , vol.25 , pp. 93-101
    • Lyu, S.Y.1    Choi, S.H.2    Park, W.B.3
  • 29
    • 0034833942 scopus 로고    scopus 로고
    • Roles of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase in apoptosis of human monoblastic leukemia U937 cells by lectin-II isolated from Korean mistletoe
    • Pae HO, Oh GS, Kim NY, Shin MK, Lee HS, Yun YG et al. (2001) Roles of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase in apoptosis of human monoblastic leukemia U937 cells by lectin-II isolated from Korean mistletoe. In Vitr. Mol. Toxicol. 14, 99-106.
    • (2001) In Vitr. Mol. Toxicol. , vol.14 , pp. 99-106
    • Pae, H.O.1    Oh, G.S.2    Kim, N.Y.3    Shin, M.K.4    Lee, H.S.5    Yun, Y.G.6
  • 30
    • 77957604071 scopus 로고    scopus 로고
    • The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells
    • De Mejia EG, Dia VP (2010) The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells. Cancer Metastasis Rev. 29, 511-528.
    • (2010) Cancer Metastasis Rev. , vol.29 , pp. 511-528
    • De Mejia, E.G.1    Dia, V.P.2
  • 31
    • 84868197448 scopus 로고    scopus 로고
    • Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis
    • Ouyang L, Shi Z, Zhao S, Wang FT, Zhou TT, Liu B et al. (2012) Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. Cell Prolif. 45, 487-498.
    • (2012) Cell Prolif. , vol.45 , pp. 487-498
    • Ouyang, L.1    Shi, Z.2    Zhao, S.3    Wang, F.T.4    Zhou, T.T.5    Liu, B.6
  • 32
    • 84874598403 scopus 로고    scopus 로고
    • Beclin-1: autophagic regulator and therapeutic target in cancer
    • Fu LL, Cheng Y, Liu B (2013) Beclin-1: autophagic regulator and therapeutic target in cancer. Int. J. Biochem. Cell Biol. 45, 921-924.
    • (2013) Int. J. Biochem. Cell Biol. , vol.45 , pp. 921-924
    • Fu, L.L.1    Cheng, Y.2    Liu, B.3
  • 33
    • 33847754341 scopus 로고    scopus 로고
    • Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma mode
    • Chang CP, Yang MC, Liu HS, Lin YS, Lei HY (2007) Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma mode. Hepatology 45, 286-296.
    • (2007) Hepatology , vol.45 , pp. 286-296
    • Chang, C.P.1    Yang, M.C.2    Liu, H.S.3    Lin, Y.S.4    Lei, H.Y.5
  • 34
    • 63449123137 scopus 로고    scopus 로고
    • Lectin of Concanavalin A as an anti-hepatoma therapeutic agent
    • Lei HY, Chang CP (2009) Lectin of Concanavalin A as an anti-hepatoma therapeutic agent. J. Biomed. Sci. 16, 10.
    • (2009) J. Biomed. Sci. , vol.16 , pp. 10
    • Lei, H.Y.1    Chang, C.P.2
  • 35
    • 84864436118 scopus 로고    scopus 로고
    • Concanavalin-A-induced autophagy biomarkers requires membrane type-1 matrix metalloproteinase intracellular signaling in glioblastoma cells
    • Pratt J, Roy R, Annabi B (2012) Concanavalin-A-induced autophagy biomarkers requires membrane type-1 matrix metalloproteinase intracellular signaling in glioblastoma cells. Glycobiology 22, 1245-1255.
    • (2012) Glycobiology , vol.22 , pp. 1245-1255
    • Pratt, J.1    Roy, R.2    Annabi, B.3
  • 37
    • 0035569140 scopus 로고    scopus 로고
    • Anticancer activity of rViscumin (recombinant mistletoe lectin) in tumor colonization models with immunocompetent mice
    • Schaffrath B, Mengs U, Schwarz T, Hilgers RD, Beuth J, Möckel B et al. (2001) Anticancer activity of rViscumin (recombinant mistletoe lectin) in tumor colonization models with immunocompetent mice. Anticancer Res. 21, 3981-3987.
    • (2001) Anticancer Res. , vol.21 , pp. 3981-3987
    • Schaffrath, B.1    Mengs, U.2    Schwarz, T.3    Hilgers, R.D.4    Beuth, J.5    Möckel, B.6
  • 38
    • 84865565698 scopus 로고    scopus 로고
    • Korean mistletoe lectin regulates self-renewal of placenta-derived mesenchymal stem cells via autophagic mechanisms
    • Choi JH, Lyu SY, Lee HJ, Jung J, Park WB, Kim GJ (2012) Korean mistletoe lectin regulates self-renewal of placenta-derived mesenchymal stem cells via autophagic mechanisms. Cell Prolif. 45, 420-429.
    • (2012) Cell Prolif. , vol.45 , pp. 420-429
    • Choi, J.H.1    Lyu, S.Y.2    Lee, H.J.3    Jung, J.4    Park, W.B.5    Kim, G.J.6
  • 39
    • 65249144593 scopus 로고    scopus 로고
    • Induction of apoptosis by concanavalin A and its molecular mechanisms in cancer cells
    • Liu B, Min MW, Bao JK (2009) Induction of apoptosis by concanavalin A and its molecular mechanisms in cancer cells. Autophagy 5, 432-433.
    • (2009) Autophagy , vol.5 , pp. 432-433
    • Liu, B.1    Min, M.W.2    Bao, J.K.3
  • 41
    • 84865547975 scopus 로고    scopus 로고
    • Identification of microRNA-regulated autophagic pathways in plant lectin-induced cancer cell death
    • Fu LL, Zhao X, Xu HL, Wen X, Wang SY, Liu B et al. (2012) Identification of microRNA-regulated autophagic pathways in plant lectin-induced cancer cell death. Cell Prolif. 45, 477-485.
    • (2012) Cell Prolif. , vol.45 , pp. 477-485
    • Fu, L.L.1    Zhao, X.2    Xu, H.L.3    Wen, X.4    Wang, S.Y.5    Liu, B.6
  • 42
    • 81355138736 scopus 로고    scopus 로고
    • In silico analysis of molecular mechanisms of GNA-related lectin-induced cancer cell death from carbohydrate-binding motif evolution hypothesis
    • Yu QJ, Li ZY, Yao S, Ming M, Wang SY, Liu B et al. (2011) In silico analysis of molecular mechanisms of GNA-related lectin-induced cancer cell death from carbohydrate-binding motif evolution hypothesis. Appl. Biochem. Biotechnol. 165, 1037-1046.
    • (2011) Appl. Biochem. Biotechnol. , vol.165 , pp. 1037-1046
    • Yu, Q.J.1    Li, Z.Y.2    Yao, S.3    Ming, M.4    Wang, S.Y.5    Liu, B.6
  • 43
    • 77956036448 scopus 로고    scopus 로고
    • Lectin microarrays for glycomic analysis
    • Gupta G, Surolia A, Sampathkumar SG (2010) Lectin microarrays for glycomic analysis. OMICS 14, 419-436.
    • (2010) OMICS , vol.14 , pp. 419-436
    • Gupta, G.1    Surolia, A.2    Sampathkumar, S.G.3
  • 44
    • 32144434430 scopus 로고    scopus 로고
    • Lectins as bioactive plant proteins: a potential in cancer treatment
    • De Mejía EG, Prisecaru VI (2005) Lectins as bioactive plant proteins: a potential in cancer treatment. Crit. Rev. Food Sci. Nutr. 45, 425-445.
    • (2005) Crit. Rev. Food Sci. Nutr. , vol.45 , pp. 425-445
    • De Mejía, E.G.1    Prisecaru, V.I.2
  • 45


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.