Insulin restores myocardial presynaptic sympathetic neuronal integrity in insulin-resistant diabetic rats

Journal of Nuclear Cardiology

Volumn 20, Issue 5, 2013, Pages 845-856

  Thackeray, James T ^a,b,c   Dekemp, Robert A ^a   Beanlands, Rob S ^a,b   Dasilva, Jean N ^a,b  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Diastolic dysfunction; glycemic therapy; meta hydroxyephedrine (HED); microPET imaging; norepinephrine

Indexed keywords

3 HYDROXYEPHEDRINE; BETA ADRENERGIC RECEPTOR; CARBON 11; CARRIER PROTEINS AND BINDING PROTEINS; INSULIN; METFORMIN; NORADRENALIN; NOREPINEPHRINE REUPTAKE TRANSPORTER PROTEIN; UNCLASSIFIED DRUG;

ADRENALIN BLOOD LEVEL; ADRENERGIC TRANSMISSION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DIABETES MELLITUS; DIASTOLIC DYSFUNCTION; DISEASE DURATION; DOPPLER ECHOCARDIOGRAPHY; DOSE RESPONSE; DRUG DOSE TITRATION; HEART CONDUCTION; HEART NERVE; HEART RATE VARIABILITY; IN VITRO STUDY; INSULIN RESISTANCE; INSULIN TREATMENT; MALE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; CONTRAST MEDIA; DIABETES MELLITUS, EXPERIMENTAL; ECHOCARDIOGRAPHY; EPHEDRINE; GLUCOSE CLAMP TECHNIQUE; HEART; INSULIN; MALE; METFORMIN; MITRAL VALVE; MYOCARDIUM; NEURONS; NOREPINEPHRINE; POSITRON-EMISSION TOMOGRAPHY; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY; RISK; SYMPATHETIC NERVOUS SYSTEM; TELEMETRY; ULTRASONOGRAPHY, DOPPLER;

EID: 84884702782     PISSN: 10713581     EISSN: 15326551     Source Type: Journal    
DOI: 10.1007/s12350-013-9759-2     Document Type: Article

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