-
1
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
McInnes IB, Schett G. The pathogenesis of rheumatoid arthritis. N Engl J Med. 2011;365:2205-2219.
-
(2011)
N Engl J Med
, vol.365
, pp. 2205-2219
-
-
McInnes, I.B.1
Schett, G.2
-
2
-
-
70349774455
-
Minireview: Live and let die: Molecular effects of glucocorticoids on bone cells
-
Hofbauer LC, Rauner M. Minireview: live and let die: molecular effects of glucocorticoids on bone cells. Mol Endocrinol. 2009;23:1525-1531.
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1525-1531
-
-
Hofbauer, L.C.1
Rauner, M.2
-
3
-
-
34548554688
-
Glucocorticoid-induced osteoporosis: Pathophysiology and therapy
-
DOI 10.1007/s00198-007-0394-0
-
Canalis E, Mazziotti G, Giustina A, Bilezikian JP. Glucocorticoid-induced osteoporosis: pathophysiology and therapy. Osteoporos Int. 2007;18:1319-1328. (Pubitemid 47389469)
-
(2007)
Osteoporosis International
, vol.18
, Issue.10
, pp. 1319-1328
-
-
Canalis, E.1
Mazziotti, G.2
Giustina, A.3
Bilezikian, J.P.4
-
4
-
-
1642546419
-
Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength
-
DOI 10.1210/en.2003-0990
-
O'Brien CA, Jia D, Plotkin LI, et al. Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength. Endocrinology. 2004;145:1835-1841. (Pubitemid 38402392)
-
(2004)
Endocrinology
, vol.145
, Issue.4
, pp. 1835-1841
-
-
O'Brien, C.A.1
Jia, D.2
Plotkin, L.I.3
Bellido, T.4
Powers, C.C.5
Stewart, S.A.6
Manolagas, S.C.7
Weinstein, R.S.8
-
5
-
-
77956277161
-
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor
-
Rauch A, Seitz S, Baschant U, et al. Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor. Cell Metab. 2011;11:517-531.
-
(2011)
Cell Metab
, vol.11
, pp. 517-531
-
-
Rauch, A.1
Seitz, S.2
Baschant, U.3
-
6
-
-
1942424854
-
Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: Novel mechanism of glucocorticoid-induced osteoporosis
-
DOI 10.1016/j.bbrc.2004.04.025, PII S0006291X04007338
-
Ohnaka K, Taniguchi H, Kawate H, Nawata H, Takayanagi R. Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: novel mechanism of glucocorticoid-induced osteoporosis. Biochem Biophys Res Commun. 2004;318:259-264. (Pubitemid 38526274)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.318
, Issue.1
, pp. 259-264
-
-
Ohnaka, K.1
Taniguchi, H.2
Kawate, H.3
Nawata, H.4
Takayanagi, R.5
-
7
-
-
69049083492
-
Denosumab for prevention of fractures in postmenopausal women with osteoporosis
-
Cummings SR, San Martin J, McClung MR, et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med. 2009;361:756-765.
-
(2009)
N Engl J Med
, vol.361
, pp. 756-765
-
-
Cummings, S.R.1
San Martin, J.2
McClung, M.R.3
-
8
-
-
0033304809
-
Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: Potential paracrine mechanisms of glucocorticoid-induced osteoporosis
-
Hofbauer LC, Gori F, Riggs BL, et al. Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis. Endocrinology. 1999;140:4382-4389. (Pubitemid 30666099)
-
(1999)
Endocrinology
, vol.140
, Issue.10
, pp. 4382-4389
-
-
Hofbauer, L.C.1
Gori, F.2
Riggs, B.L.3
Lacey, D.L.4
Dunstan, C.R.5
Spelsberg, T.C.6
Khosla, S.7
-
9
-
-
78650850288
-
Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells
-
Rauner M, Goettsch C, Stein N, et al. Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells. Endocrinology. 2011;152:103-112.
-
(2011)
Endocrinology
, vol.152
, pp. 103-112
-
-
Rauner, M.1
Goettsch, C.2
Stein, N.3
-
10
-
-
66049092304
-
Prevention of glucocorticoid-induced bone loss in mice by inhibition of RANKL
-
Hofbauer LC, Zeitz U, Schoppet M, et al. Prevention of glucocorticoid-induced bone loss in mice by inhibition of RANKL. Arthritis Rheum. 2009;60:1427-1437.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1427-1437
-
-
Hofbauer, L.C.1
Zeitz, U.2
Schoppet, M.3
-
11
-
-
0037126620
-
Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor
-
DOI 10.1093/emboj/20.24.7168
-
Reichardt HM, Tuckermann JP, Göttlicher M, et al. Repression of inflammatory responses in the absence of DNA binding by the glucocorticoid receptor. EMBO J. 2001;20:7168-7173. (Pubitemid 34062308)
-
(2001)
EMBO Journal
, vol.20
, Issue.24
, pp. 7168-7173
-
-
Reichardt, H.M.1
Tuckermann, J.P.2
Gottlicher, M.3
Vujic, M.4
Weih, F.5
Angel, P.6
Herrlich, P.7
Schutz, G.8
-
12
-
-
82755190623
-
Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells
-
Baschant U, Frappart L, Rauchhaus U, et al. Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells. Proc Natl Acad Sci USA. 2011;108:19317-19322.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 19317-19322
-
-
Baschant, U.1
Frappart, L.2
Rauchhaus, U.3
-
13
-
-
0347719371
-
Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects
-
DOI 10.1073/pnas.0300372101
-
Schäcke H, Schottelius A, Do W, Strehlke P, Jaroch S, Schmees N. Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects. Proc Natl Acad Sci USA. 2004;101:227-232. (Pubitemid 38084232)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.1
, pp. 227-232
-
-
Schacke, H.1
Schottelius, A.2
Docke, W.-D.3
Strehlke, P.4
Jaroch, S.5
Schmees, N.6
Rehwinkel, H.7
Hennekes, H.8
Asadullah, K.9
-
14
-
-
77952950546
-
Selective glucocorticoid receptor modulators
-
De Bosscher K. Selective glucocorticoid receptor modulators. J Steroid Biochem. 2010;120:96-104.
-
(2010)
J Steroid Biochem
, vol.120
, pp. 96-104
-
-
De Bosscher, K.1
-
15
-
-
27644492383
-
A fully dissociated compound of plant origin for inflammatory gene repression
-
DOI 10.1073/pnas.0505554102
-
De Bosscher K, Vanden Berghe W, Beck IM, et al. A fully dissociated compound of plant origin for inflammatory gene repression. Proc Natl Acad Sci USA. 2005;102:15827-15832. (Pubitemid 41552827)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.44
, pp. 15827-15832
-
-
De Bosscher, K.1
Berghe, W.V.2
Beck, I.M.E.3
Van Molle, W.4
Hennuyer, N.5
Hapgood, J.6
Libert, C.7
Staels, B.8
Louw, A.9
Haegeman, G.10
-
16
-
-
0031012174
-
Mechanism for the stabilization in vivo of the aziridine precursor 2-(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride by serum proteins
-
DOI 10.1016/S0006-2952(96)00661-2, PII S0006295296006612
-
Louw A, Swart P, DeKock SS, Van der Merwe KJ. Mechanism for the stabilization in vivo of the aziridine precursor 2-(4-acetoxyphe-nyl)-2-chloro- N-methyl-ethylammonium chloride by serum proteins. Biochem Pharmacol. 1997;53:189-197. (Pubitemid 27013474)
-
(1997)
Biochemical Pharmacology
, vol.53
, Issue.2
, pp. 189-197
-
-
Louw, A.1
Swart, P.2
De Kock, S.S.3
Van Der, M.K.J.4
-
17
-
-
0033325103
-
Salsola tuberculatiformis Botschantzev and an aziridine precursor analog mediate the in vivo increase in free corticosterone and decrease in corticosteroid-binding globulin in female wistar rats
-
Louw A, Swart P. Salsola tuberculatiformis Botschantzev and an aziridine precursor analog mediate the in vivo increase in free corticosterone and decrease in corticosteroid-binding globulin in female Wistar rats. Endocrinology. 1999;140:2044-2053. (Pubitemid 30636441)
-
(1999)
Endocrinology
, vol.140
, Issue.5
, pp. 2044-2053
-
-
Louw, A.1
Swart, P.2
-
18
-
-
40849142555
-
A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis
-
Dewint P, Gossye V, De Bosscher K, et al. A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis. J Immunol. 2008;180:2608-2615.
-
(2008)
J Immunol
, vol.180
, pp. 2608-2615
-
-
Dewint, P.1
Gossye, V.2
De Bosscher, K.3
-
19
-
-
77949524864
-
Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis
-
Wust S, Tischner D, John M, et al. Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis. PLoS One. 2009;4:e8202.
-
(2009)
PLoS One
, vol.4
-
-
Wust, S.1
Tischner, D.2
John, M.3
-
20
-
-
75149156175
-
Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis
-
Van Loo G, Sze M, Bougarne N, et al. Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis. Mol Endocrinol. 2010;24:310-322.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 310-322
-
-
Van Loo, G.1
Sze, M.2
Bougarne, N.3
-
21
-
-
84867559755
-
Selective glucocorticoid receptor modulation maintains bone mineral density in mice
-
Thiele S, Ziegler N, Tsourdi E, et al. Selective glucocorticoid receptor modulation maintains bone mineral density in mice. J Bone Miner Res. 2012;27:2242-2250.
-
(2012)
J Bone Miner Res
, vol.27
, pp. 2242-2250
-
-
Thiele, S.1
Ziegler, N.2
Tsourdi, E.3
-
22
-
-
36949009473
-
Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen
-
Inglis JJ, Criado G, Medghalchi M, et al. Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen. Arthritis Res Ther. 2007;9:R113.
-
(2007)
Arthritis Res Ther
, vol.9
-
-
Inglis, J.J.1
Criado, G.2
Medghalchi, M.3
-
23
-
-
0023488581
-
Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
-
Parfitt AM, Drezner MK, Glorieux FH, et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res. 1987;2:595-610.
-
(1987)
J Bone Miner Res
, vol.2
, pp. 595-610
-
-
Parfitt, A.M.1
Drezner, M.K.2
Glorieux, F.H.3
-
24
-
-
70349247894
-
Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects
-
Zhang Z, Zhang Z-Y, Schluesener HJ. Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects. J Immunol. 2009;183:3081-3091.
-
(2009)
J Immunol
, vol.183
, pp. 3081-3091
-
-
Zhang, Z.1
Zhang, Z.-Y.2
Schluesener, H.J.3
-
25
-
-
79954592084
-
An anti-inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation
-
Rauch A, Gossye V, Bracke D, et al. An anti-inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation. FASEB J. 25:1323-1332.
-
FASEB J
, vol.25
, pp. 1323-1332
-
-
Rauch, A.1
Gossye, V.2
Bracke, D.3
-
26
-
-
84858684891
-
Selective glucocorticoid receptor agonists for the treatment of inflammatory bowel disease: Studies in mice with acute trinitrobenzene sulfonic acid colitis
-
Reuter KC, Grunwitz CR, Kaminski BM, Steinhilber D, Radeke HH, Stein J. Selective glucocorticoid receptor agonists for the treatment of inflammatory bowel disease: studies in mice with acute trinitrobenzene sulfonic acid colitis. J Pharmacol Exp Ther. 2012;341:68-80.
-
(2012)
J Pharmacol Exp Ther
, vol.341
, pp. 68-80
-
-
Reuter, K.C.1
Grunwitz, C.R.2
Kaminski, B.M.3
Steinhilber, D.4
Radeke, H.H.5
Stein, J.6
-
27
-
-
84859494247
-
Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells
-
Liberman AC, Antunica-Noguerol M, Ferraz-de-Paula V, et al. Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells. PloS one. 2012;7:e35155.
-
(2012)
PloS One
, vol.7
-
-
Liberman, A.C.1
Antunica-Noguerol, M.2
Ferraz-de-Paula, V.3
-
28
-
-
0032774416
-
FVB/N (H2(q)) mouse is resistant to arthritis induction and exhibits a genomic deletion of T-cell receptor V beta gene segments
-
DOI 10.1007/s002510050564
-
Osman GE, Hannibal MC, Anderson JP, Lasky SR, Ladiges WC, Hood L. FVB/N [H2(q)] mouse is resistant to arthritis induction and exhibits a genomic deletion of T-cell receptor V β gene segments. Immunogenetics. 1999;49:851-859. (Pubitemid 29381446)
-
(1999)
Immunogenetics
, vol.49
, Issue.10
, pp. 851-859
-
-
Osman, G.E.1
Hannibal, M.C.2
Anderson, J.P.3
Lasky, S.R.4
Ladiges, W.C.5
Hood, L.6
-
29
-
-
0033990532
-
Influence of an aziridine precursor on the in vitro binding parameters of rat and ovine corticosteroid-binding globulin (CBG)
-
Louw A, Swart P, Allie F. Influence of an aziridine precursor on the in vitro binding parameters of rat and ovine corticosteroid-binding globulin (CBG). Biochem Pharmacol. 2000;59:167-175.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 167-175
-
-
Louw, A.1
Swart, P.2
Allie, F.3
-
30
-
-
84867525648
-
Selective glucocorticoid receptor agonists: Glucocorticoid therapy with no regrets?
-
Cooper MS, Zhou H, Seibel MJ. Selective glucocorticoid receptor agonists: glucocorticoid therapy with no regrets? J Bone Miner Res. 2012;27:2238-2241.
-
(2012)
J Bone Miner Res
, vol.27
, pp. 2238-2241
-
-
Cooper, M.S.1
Zhou, H.2
Seibel, M.J.3
-
31
-
-
44449152438
-
Use of a portable thermal imaging unit as a rapid, quantitative method of evaluating inflammation and experimental arthritis
-
Sanchez BM, Lesch M, Brammer D, Bove SE, Thiel M, Kilgore KS. Use of a portable thermal imaging unit as a rapid, quantitative method of evaluating inflammation and experimental arthritis. J Pharmacol Toxicol Methods. 2008;57:169-175.
-
(2008)
J Pharmacol Toxicol Methods
, vol.57
, pp. 169-175
-
-
Sanchez, B.M.1
Lesch, M.2
Brammer, D.3
Bove, S.E.4
Thiel, M.5
Kilgore, K.S.6
-
32
-
-
33144488000
-
Thermal signature analysis as a novel method for evaluating inflammatory arthritis activity
-
DOI 10.1136/ard.2004.035246
-
Brenner M, Braun C, Oster M, Gulko PS. Thermal signature analysis as a novel method for evaluating inflammatory arthritis activity. Ann Rheum Dis. 2006;65:306-311. (Pubitemid 43268217)
-
(2006)
Annals of the Rheumatic Diseases
, vol.65
, Issue.3
, pp. 306-311
-
-
Brenner, M.1
Braun, C.2
Oster, M.3
Gulko, P.S.4
|