Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure

Molecular Psychiatry

Volumn 18, Issue 10, 2013, Pages 1125-1135

  Hill, M N ^a,b   Kumar, S A ^c   Filipski, S B ^b   Iverson, M ^d   Stuhr, K L ^d   Keith, J M ^e   Cravatt, B F ^f   Hillard, C J ^d   Chattarji, S ^c   McEwen, B S ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b ROCKEFELLER UNIVERSITY   (United States)

^c TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

^e JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^f SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

anandamide; anxiety; basolateral amygdala; cannabinoid; FAAH; stress

Indexed keywords

ENDOCANNABINOID; FATTY ACID AMIDASE; FATTY ACID AMIDASE INHIBITOR; JNJ 5003; N ARACHIDONYLETHANOLAMINE; UNCLASSIFIED DRUG;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BASOLATERAL AMYGDALA; BRAIN FUNCTION; CELL DENSITY; CHRONIC STRESS; CONTROLLED STUDY; DENDRITIC CELL; EMOTION; ENZYME ACTIVITY; HYPERACTIVITY; MALE; MOUSE; NERVE CELL PLASTICITY; NEUROANATOMY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL;

AMIDOHYDROLASES; AMYGDALA; ANIMALS; ANXIETY; CHRONIC DISEASE; CYCLOHEXANOLS; DENDRITES; DRUG EVALUATION, PRECLINICAL; ENDOCANNABINOIDS; EXPLORATORY BEHAVIOR; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; RESTRAINT, PHYSICAL; STRESS, PSYCHOLOGICAL;

EID: 84884674660     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2012.90     Document Type: Article

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