Stem cells: Insights into the secretome

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1834, Issue 11, 2013, Pages 2380-2384

  Makridakis, Manousos ^a   Roubelakis, Maria G ^a,b   Vlahou, Antonia ^a  

^a BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Proteomics; Secretome; Stem cells

Indexed keywords

PROTEOME; SECRETOME; UNCLASSIFIED DRUG;

ADIPOSE DERIVED STEM CELL; ADULT STEM CELL; BONE MARROW CELL; CANCER STEM CELL; EMBRYONIC STEM CELL; HUMAN; MESENCHYMAL STEM CELL; MESENCHYMAL STROMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEOMICS; REGENERATIVE MEDICINE; REVIEW; STEM CELL; UMBILICAL VEIN ENDOTHELIAL CELL;

2 DIMENSIONAL DIFFERENTIAL GEL ELECTROPHORESIS; 2 DIMENSIONAL ELECTROPHORESIS; 2D-DIGE; 2DE; ACUTE HEPATIC FAILURE; AF-MSCS; AHF; ALZHEIMER'S TRUNCATED TAU; AMNIOTIC FLUID DERIVED MESENCHYMAL STEM CELLS; AT TAU; BMSCS; BONE MARROW DERIVED MESENCHYMAL STEM CELLS; CANCER STEM CELLS; CHRONIC KIDNEY DISEASE; CKD; CM; CONDITIONED MEDIUM; CSCS; CYR 61; CYSTEINE RICH PROTEIN 61; GELC-MS/MS; GLIOBLASTOMA STEM LIKE CELLS; GRO; GROWTH RELATED ONCOGENE; GSCS; HAFSCS; HAMSCS; HASCS; HBMSCS; HDGF; HEPATIC PROGENITOR-LIKE CELLS; HEPATOMA DERIVED GROWTH FACTOR; HESCS; HMADS; HPL; HUMAN ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS; HUMAN ADIPOSE TISSUE-DERIVED STEM CELLS; HUMAN AMNIOTIC FLUID STEM CELLS; HUMAN BONE MARROW-DERIVED MESENCHYMAL STEM CELLS; HUMAN EMBRYONIC STEM CELLS; HUMAN MULTIPOTENT ADIPOSE-DERIVED STEM CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUVEC; IE-MS; IFN Γ; IL-8; INTERFERON GAMMA; INTERFERON GAMMA-INDUCED PROTEIN 10; INTERLEUKIN 8; IP-10; ITERATIVE EXCLUSION-MASS SPECTROMETRY; LEFT-RIGHT DETERMINATION FACTOR 1; LEFTY 1; MARROW ISOLATED ADULT MULTILINEAGE INDUCIBLE CELLS; MASS SPECTROMETRY; MCP-1; MEF; MESCS; MIAMI; MMSCS; MONOCYTE CHEMOTACTIC PROTEIN 1; MOUSE EMBRYONIC FIBROBLAST; MS; MURINE EMBRYONIC STEM CELLS; MURINE MESENCHYMAL STEM CELLS; NEURAL STEM CELLS; NSCS; OSM; OSTEOGENIC MEDIUM; OVARIECTOMIZED; OVX; PAI-1; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEOMICS; SDF-1; SDS PAGE COMBINED WITH LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; SECRETOME; SMOC1; SPARC RELATED MODULAR CALCIUM-BINDING PROTEIN 1; STEM CELLS; STROMAL CELL-DERIVED FACTOR 1; TNF-Α; TUMOR NECROSIS FACTOR ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR; VEGF;

ANIMALS; HUMANS; MODELS, MOLECULAR; PROTEOME; PROTEOMICS; SECRETORY PATHWAY; STEM CELLS;

EID: 84884671483     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2013.01.032     Document Type: Review

References (56)

1. S.J. Morrison, and J. Kimble Asymmetric and symmetric stem-cell divisions in development and cancer Nature 441 2006 1068 1074 (Pubitemid 43990718)
2. I. Klimanskaya, N. Rosenthal, and R. Lanza Derive and conquer: sourcing and differentiating stem cells for therapeutic applications Nat. Rev. Drug Discov. 7 2008 131 142 (Pubitemid 351194061)
3. K.I. Pappa, and N.P. Anagnou Novel sources of fetal stem cells: where do they fit on the developmental continuum? Regen. Med. 4 2009 423 433
4. M.G. Roubelakis, O. Trohatou, and N.P. Anagnou Amniotic fluid and amniotic membrane stem cells: marker discovery Stem Cells Int. 2012 2012 107836
5. M. Makridakis, and A. Vlahou Secretome proteomics for discovery of cancer biomarkers J. Proteomics 73 2010 2291 2305
6. M.P. Pavlou, and E.P. Diamandis The cancer cell secretome: a good source for discovering biomarkers? J. Proteomics 73 2010 1896 1906
7. H. Skalnikova, J. Motlik, S.J. Gadher, and H. Kovarova Mapping of the secretome of primary isolates of mammalian cells, stem cells and derived cell lines Proteomics 11 2011 691 708
8. H. Bouws, A. Wattenberg, and H. Zorn Fungal secretomes - nature's toolbox for white biotechnology Appl. Microbiol. Biotechnol. 80 2008 381 388
9. M.G. Katz-Jaffe, S. McReynolds, D.K. Gardner, and W.B. Schoolcraft The role of proteomics in defining the human embryonic secretome Mol. Hum. Reprod. 15 2009 271 277
10. A. Farina, C. D'Aniello, V. Severino, D.F. Hochstrasser, A. Parente, G. Minchiotti, and A. Chambery Temporal proteomic profiling of embryonic stem cell secretome during cardiac and neural differentiation Proteomics 11 2011 3972 3982
11. S. Roche, G. D'Ippolito, L.A. Gomez, T. Bouckenooghe, S. Lehmann, C.N. Montero-Menei, and P.C. Schiller Comparative analysis of protein expression of three stem cell populations: Models of cytokine delivery system in vivo Int. J. Pharm. 440 2013 72 82
12. M. Stastna, and J.E. Van Eyk Secreted proteins as a fundamental source for biomarker discovery Proteomics 12 2012 722 735
13. J.C. Mountford Human embryonic stem cells: origins, characteristics and potential for regenerative therapy Transfus. Med. 18 2008 1 12 (Pubitemid 351239314)
14. P. Sarkar, S.M. Randall, D.C. Muddiman, and B.M. Rao Targeted proteomics of the secretory pathway reveals the secretome of mouse embryonic fibroblasts and human embryonic stem cells Mol. Cell. Proteomics 11 2012 1829 1839
15. S.C. Bendall, C. Hughes, J.L. Campbell, M.H. Stewart, P. Pittock, S. Liu, E. Bonneil, P. Thibault, M. Bhatia, and G.A. Lajoie An enhanced mass spectrometry approach reveals human embryonic stem cell growth factors in culture Mol. Cell. Proteomics 8 2009 421 432
16. A.J. Friedenstein, R.K. Chailakhyan, N.V. Latsinik, A.F. Panasyuk, and I.V. Keiliss-Borok Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo Transplantation 17 1974 331 340
17. B. Delorme, J. Ringe, C. Pontikoglou, J. Gaillard, A. Langonne, L. Sensebe, D. Noel, C. Jorgensen, T. Haupl, and P. Charbord Specific lineage-priming of bone marrow mesenchymal stem cells provides the molecular framework for their plasticity Stem Cells 27 2009 1142 1151
18. K. English, A. French, and K.J. Wood Mesenchymal stromal cells: facilitators of successful transplantation? Cell Stem Cell 7 2010 431 442
19. F. Mosna, L. Sensebe, and M. Krampera Human bone marrow and adipose tissue mesenchymal stem cells: a user's guide Stem Cells Dev. 19 2010 1449 1470
20. D.J. Prockop Repair of tissues by adult stem/progenitor cells (MSCs): controversies, myths, and changing paradigms Mol. Ther. 17 2009 939 946
21. E. Martin-Rendon, D. Sweeney, F. Lu, J. Girdlestone, C. Navarrete, and S.M. Watt 5-Azacytidine-treated human mesenchymal stem/progenitor cells derived from umbilical cord, cord blood and bone marrow do not generate cardiomyocytes in vitro at high frequencies Vox Sang. 95 2008 137 148 (Pubitemid 351951902)
22. G. Qin, M. Ii, M. Silver, A. Wecker, E. Bord, H. Ma, M. Gavin, D.A. Goukassian, Y.S. Yoon, T. Papayannopoulou, T. Asahara, M. Kearney, T. Thorne, C. Curry, L. Eaton, L. Heyd, D. Dinesh, R. Kishore, Y. Zhu, and D.W. Losordo Functional disruption of alpha4 integrin mobilizes bone marrow-derived endothelial progenitors and augments ischemic neovascularization J. Exp. Med. 203 2006 153 163 (Pubitemid 43139654)
23. D.L. Troyer, and M.L. Weiss Wharton's jelly-derived cells are a primitive stromal cell population Stem Cells 26 2008 591 599
24. Y.A. Choi, J. Lim, K.M. Kim, B. Acharya, J.Y. Cho, Y.C. Bae, H.I. Shin, S.Y. Kim, and E.K. Park Secretome analysis of human BMSCs and identification of SMOC1 as an important ECM protein in osteoblast differentiation J. Proteome Res. 9 2010 2946 2956
25. J.M. Kim, J. Kim, Y.H. Kim, K.T. Kim, S.H. Ryu, T.G. Lee, and P.G. Suh Comparative secretome analysis of human bone marrow-derived mesenchymal stem cells during osteogenesis J. Cell. Physiol. 228 2013 216 224
26. A. Cignarelli, S. Perrini, R. Ficarella, A. Peschechera, P. Nigro, and F. Giorgino Human adipose tissue stem cells: relevance in the pathophysiology of obesity and metabolic diseases and therapeutic applications Expert Rev. Mol. Med. 14 2012 e19
27. P. Trayhurn Endocrine and signalling role of adipose tissue: new perspectives on fat Acta Physiol. Scand. 184 2005 285 293 (Pubitemid 41039735)
28. P.E. Scherer, S. Williams, M. Fogliano, G. Baldini, and H.F. Lodish A novel serum protein similar to C1q, produced exclusively in adipocytes J. Biol. Chem. 270 1995 26746 26749
29. Y. Zhang, R. Proenca, M. Maffei, M. Barone, L. Leopold, and J.M. Friedman Positional cloning of the mouse obese gene and its human homologue Nature 372 1994 425 432 (Pubitemid 24365442)
30. F. Samad, K. Yamamoto, and D.J. Loskutoff Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide J. Clin. Invest. 97 1996 37 46
31. C.M. Steppan, S.T. Bailey, S. Bhat, E.J. Brown, R.R. Banerjee, C.M. Wright, H.R. Patel, R.S. Ahima, and M.A. Lazar The hormone resistin links obesity to diabetes Nature 409 2001 307 312 (Pubitemid 32151228)
32. K. Hida, J. Wada, J. Eguchi, H. Zhang, M. Baba, A. Seida, I. Hashimoto, T. Okada, A. Yasuhara, A. Nakatsuka, K. Shikata, S. Hourai, J. Futami, E. Watanabe, Y. Matsuki, R. Hiramatsu, S. Akagi, H. Makino, and Y.S. Kanwar Visceral adipose tissue-derived serine protease inhibitor: a unique insulin-sensitizing adipocytokine in obesity Proc. Natl. Acad. Sci. U. S. A. 102 2005 10610 10615 (Pubitemid 41061602)
33. S. Zvonic, M. Lefevre, G. Kilroy, Z.E. Floyd, J.P. DeLany, I. Kheterpal, A. Gravois, R. Dow, A. White, X. Wu, and J.M. Gimble Secretome of primary cultures of human adipose-derived stem cells: modulation of serpins by adipogenesis Mol. Cell. Proteomics 6 2007 18 28 (Pubitemid 46152688)
34. M.J. Lee, J. Kim, M.Y. Kim, Y.S. Bae, S.H. Ryu, T.G. Lee, and J.H. Kim Proteomic analysis of tumor necrosis factor-alpha-induced secretome of human adipose tissue-derived mesenchymal stem cells J. Proteome Res. 9 2010 1754 1762
35. C. Chiellini, O. Cochet, L. Negroni, M. Samson, M. Poggi, G. Ailhaud, M.C. Alessi, C. Dani, and E.Z. Amri Characterization of human mesenchymal stem cell secretome at early steps of adipocyte and osteoblast differentiation BMC Mol. Biol. 9 2008 26
36. E. Sugihara, and H. Saya Complexity of cancer stem cells Int. J. Cancer 132 2013 1249 1259
37. M.F. Clarke, J.E. Dick, P.B. Dirks, C.J. Eaves, C.H. Jamieson, D.L. Jones, J. Visvader, I.L. Weissman, and G.M. Wahl Cancer stem cells - perspectives on current status and future directions: AACR Workshop on cancer stem cells Cancer Res. 66 2006 9339 9344 (Pubitemid 44623625)
38. C. Thirant, E.M. Galan-Moya, L.G. Dubois, S. Pinte, P. Chafey, C. Broussard, P. Varlet, B. Devaux, F. Soncin, J. Gavard, M.P. Junier, and H. Chneiweiss Differential proteomic analysis of human glioblastoma and neural stem cells reveals HDGF as a novel angiogenic secreted factor Stem Cells 30 2012 845 853
39. L. Cheng, S. Bao, and J.N. Rich Potential therapeutic implications of cancer stem cells in glioblastoma Biochem. Pharmacol. 80 2010 654 665
40. H. Sarojini, R. Estrada, H. Lu, S. Dekova, M.J. Lee, R.D. Gray, and E. Wang PEDF from mouse mesenchymal stem cell secretome attracts fibroblasts J. Cell. Biochem. 104 2008 1793 1802
41. R. Estrada, N. Li, H. Sarojini, J. An, M.J. Lee, and E. Wang Secretome from mesenchymal stem cells induces angiogenesis via Cyr61 J. Cell. Physiol. 219 2009 563 571
42. A. van Koppen, J.A. Joles, B.W. van Balkom, S.K. Lim, D. de Kleijn, R.H. Giles, and M.C. Verhaar Human embryonic mesenchymal stem cell-derived conditioned medium rescues kidney function in rats with established chronic kidney disease PLoS One 7 2012 e38746
43. Y. Wang, E. Bakota, B.H. Chang, M. Entman, J.D. Hartgerink, and F.R. Danesh Peptide nanofibers preconditioned with stem cell secretome are renoprotective J. Am. Soc. Nephrol. 22 2011 704 717
44. E.L. Bakota, Y. Wang, F.R. Danesh, and J.D. Hartgerink Injectable multidomain peptide nanofiber hydrogel as a delivery agent for stem cell secretome Biomacromolecules 12 2011 1651 1657
45. T. Mirabella, M. Cilli, S. Carlone, R. Cancedda, and C. Gentili Amniotic liquid derived stem cells as reservoir of secreted angiogenic factors capable of stimulating neo-arteriogenesis in an ischemic model Biomaterials 32 2011 3689 3699
46. T. Mirabella, J. Hartinger, C. Lorandi, C. Gentili, M. van Griensven, and R. Cancedda Proangiogenic soluble factors from amniotic fluid stem cells mediate the recruitment of endothelial progenitors in a model of ischemic fasciocutaneous flap Stem Cells Dev. 21 2012 2179 2188
47. D.S. Zagoura, M.G. Roubelakis, V. Bitsika, O. Trohatou, K.I. Pappa, A. Kapelouzou, A. Antsaklis, and N.P. Anagnou Therapeutic potential of a distinct population of human amniotic fluid mesenchymal stem cells and their secreted molecules in mice with acute hepatic failure Gut 61 2012 894 906
48. B. Parekkadan, D. van Poll, K. Suganuma, E.A. Carter, F. Berthiaume, A.W. Tilles, and M.L. Yarmush Mesenchymal stem cell-derived molecules reverse fulminant hepatic failure PLoS One 2 2007 e941
49. S.C. Heo, E.S. Jeon, I.H. Lee, H.S. Kim, M.B. Kim, and J.H. Kim Tumor necrosis factor-alpha-activated human adipose tissue-derived mesenchymal stem cells accelerate cutaneous wound healing through paracrine mechanisms J. Invest. Dermatol. 131 2011 1559 1567
50. N. Zilka, M. Zilkova, Z. Kazmerova, M. Sarissky, V. Cigankova, and M. Novak Mesenchymal stem cells rescue the Alzheimer's disease cell model from cell death induced by misfolded truncated tau Neuroscience 193 2011 330 337
51. J.D. Molkentin The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression J. Biol. Chem. 275 2000 38949 38952 (Pubitemid 32058903)
52. H. Li, S. Zuo, Z. He, Y. Yang, Z. Pasha, Y. Wang, and M. Xu Paracrine factors released by GATA-4 overexpressed mesenchymal stem cells increase angiogenesis and cell survival Am. J. Physiol. Heart Circ. Physiol. 299 2010 H1772 H1781
53. S.R. Baglio, D.M. Pegtel, and N. Baldini Mesenchymal stem cell secreted vesicles provide novel opportunities in (stem) cell-free therapy Front. Physiol. 3 2012 359
54. S.H. Ranganath, O. Levy, M.S. Inamdar, and J.M. Karp Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease Cell Stem Cell 10 2012 244 258
55. M. Stastna, and J.E. Van Eyk Investigating the secretome: lessons about the cells that comprise the heart Circ. Cardiovasc. Genet. 5 2012 o8 o18
56. C.T. van Velthoven, A. Kavelaars, and C.J. Heijnen Mesenchymal stem cells as a treatment for neonatal ischemic brain damage Pediatr. Res. 71 2012 474 481