메뉴 건너뛰기




Volumn 31, Issue 7, 2013, Pages 1212-1221

In vivo and in vitro effects of RAD001 on bladder cancer

(14)  Vasconcelos Nóbrega, Carmen a   Pinto Leite, Rosario b   Arantes Rodrigues, Regina c   Ferreira, Rita d   Brochado, Paulo e   Cardoso, Maria L f   Palmeira, Carlos g,h   Salvador, Alexandre i   Guedes Teixeira, Catarina I c   Colaço, Aura c   Palomino, Luis F j   Lopes, Carlos f   Santos, Lúcio g,h   Oliveira, Paula A c  


Author keywords

Akt expressivity; Apoptosis; Bladder cancer cell lines; Mice; MTOR; N butyl N (4 hydroxybutyl) nitrosamine; Proliferation; RAD001

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN; N BUTYL N (4 HYDROXYBUTYL)NITROSAMINE; PROTEIN KINASE B;

EID: 84884671137     PISSN: 10781439     EISSN: 18732496     Source Type: Journal    
DOI: 10.1016/j.urolonc.2011.11.002     Document Type: Article
Times cited : (33)

References (30)
  • 2
    • 59949084951 scopus 로고    scopus 로고
    • Clinical Cancer Advances 2008: Major research advances in cancer treatment, prevention, and screening-a report from the American Society of Clinical Oncology
    • Winer E., Gralow J., Diller L., et al. Clinical Cancer Advances 2008: Major research advances in cancer treatment, prevention, and screening-a report from the American Society of Clinical Oncology. J Clin Oncol 2009, 27:812-826.
    • (2009) J Clin Oncol , vol.27 , pp. 812-826
    • Winer, E.1    Gralow, J.2    Diller, L.3
  • 3
    • 33746651109 scopus 로고    scopus 로고
    • Radical cystectomy for invasive bladder cancer: Long-term results of a standard procedure
    • Stein J.P., Skinner D.G. Radical cystectomy for invasive bladder cancer: Long-term results of a standard procedure. World J Urol 2006, 3:296-304.
    • (2006) World J Urol , vol.3 , pp. 296-304
    • Stein, J.P.1    Skinner, D.G.2
  • 5
    • 33646019838 scopus 로고    scopus 로고
    • Experimental bladder carcinogenesis-rodent models
    • Oliveira P.A., Colaço A., De la Cruz P.L., et al. Experimental bladder carcinogenesis-rodent models. Exp Oncol 2006, 28:2-11.
    • (2006) Exp Oncol , vol.28 , pp. 2-11
    • Oliveira, P.A.1    Colaço, A.2    De la Cruz, P.L.3
  • 6
    • 68549090703 scopus 로고    scopus 로고
    • The effects of sirolimus on urothelial lesions chemically induced in ICR mice by BBN
    • Oliveira P.A., Arantes-Rodrigues R., Sousa-Diniz C., et al. The effects of sirolimus on urothelial lesions chemically induced in ICR mice by BBN. Anticancer Res 2009, 29:3221-3226.
    • (2009) Anticancer Res , vol.29 , pp. 3221-3226
    • Oliveira, P.A.1    Arantes-Rodrigues, R.2    Sousa-Diniz, C.3
  • 7
    • 79952042552 scopus 로고    scopus 로고
    • CIS is a surrogate marker of genetic instability and field carcinogenesis in the urothelial mucosa
    • Palmeira C., Lameiras C., Amaro T., et al. CIS is a surrogate marker of genetic instability and field carcinogenesis in the urothelial mucosa. Urol Oncol 2011, 29:205-211.
    • (2011) Urol Oncol , vol.29 , pp. 205-211
    • Palmeira, C.1    Lameiras, C.2    Amaro, T.3
  • 8
    • 64249135764 scopus 로고    scopus 로고
    • Novel agents on the horizon for cancer therapy
    • Ma W.W., Adjei A.A. Novel agents on the horizon for cancer therapy. CA Cancer J Clin 2009, 59:111-137.
    • (2009) CA Cancer J Clin , vol.59 , pp. 111-137
    • Ma, W.W.1    Adjei, A.A.2
  • 9
    • 0038299000 scopus 로고    scopus 로고
    • Sirolimus: Its discovery, biological properties, and mechanism of action
    • Seghal S.N. Sirolimus: Its discovery, biological properties, and mechanism of action. Transplant Proc 2003, 35(3 Suppl):7S-14S.
    • (2003) Transplant Proc , vol.35 , Issue.3 SUPPL.
    • Seghal, S.N.1
  • 10
    • 0346995280 scopus 로고    scopus 로고
    • Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian Cells
    • Edinger A.L., Linardic C.M., Chiang G.G., et al. Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian Cells. Cancer Res 2003, 63:8451-8460.
    • (2003) Cancer Res , vol.63 , pp. 8451-8460
    • Edinger, A.L.1    Linardic, C.M.2    Chiang, G.G.3
  • 11
    • 36048990293 scopus 로고    scopus 로고
    • Sirolimus (rapamycin): From the soil of Easter Island to a bright future
    • Paghdal K., Schwartz R.A. Sirolimus (rapamycin): From the soil of Easter Island to a bright future. J Am Acad Dermatol 2007, 57:1046-1050.
    • (2007) J Am Acad Dermatol , vol.57 , pp. 1046-1050
    • Paghdal, K.1    Schwartz, R.A.2
  • 12
    • 49849098119 scopus 로고    scopus 로고
    • Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies
    • Garcia J., Danielpour D. Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies. Mol Cancer Ther 2008, 7:347-354.
    • (2008) Mol Cancer Ther , vol.7 , pp. 347-354
    • Garcia, J.1    Danielpour, D.2
  • 13
    • 9144233506 scopus 로고    scopus 로고
    • Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells
    • Boulay A., Zumstein-Mecker S., Stephan C., et al. Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells. Cancer Res 2004, 64:252-261.
    • (2004) Cancer Res , vol.64 , pp. 252-261
    • Boulay, A.1    Zumstein-Mecker, S.2    Stephan, C.3
  • 14
    • 0346362997 scopus 로고    scopus 로고
    • Rapamycins: Mechanism of action and cellular resistance
    • Huang S., Bjornsti M., Houghton P.J. Rapamycins: Mechanism of action and cellular resistance. Cancer Biol Ther 2003, 2:222-232.
    • (2003) Cancer Biol Ther , vol.2 , pp. 222-232
    • Huang, S.1    Bjornsti, M.2    Houghton, P.J.3
  • 15
    • 4344602002 scopus 로고    scopus 로고
    • The biology and clinical relevance of the PTEN tumor suppressor pathway
    • Sansal I., Sellers W.R. The biology and clinical relevance of the PTEN tumor suppressor pathway. J Clin Oncol 2004, 22:2954-2963.
    • (2004) J Clin Oncol , vol.22 , pp. 2954-2963
    • Sansal, I.1    Sellers, W.R.2
  • 16
    • 1642388492 scopus 로고    scopus 로고
    • Experience with everolimus
    • Augustine J.J., Hricik D.E. Experience with everolimus. Transplant P 2004, 36(Suppl 2S):500S-503S.
    • (2004) Transplant P , vol.36 , Issue.SUPPL. 2S
    • Augustine, J.J.1    Hricik, D.E.2
  • 18
    • 27644447574 scopus 로고    scopus 로고
    • The mammalian target of the rapamycin (mTOR) kinase pathway. Its role in tumorigenesis and targeted antitumor therapy
    • Janus A., Robak T., Smolewski P. The mammalian target of the rapamycin (mTOR) kinase pathway. Its role in tumorigenesis and targeted antitumor therapy. Cell Mol Biol Lett 2005, 10:479-498.
    • (2005) Cell Mol Biol Lett , vol.10 , pp. 479-498
    • Janus, A.1    Robak, T.2    Smolewski, P.3
  • 19
    • 17444416737 scopus 로고    scopus 로고
    • Rapamycin and tumor growth: Mechanism behind its anticancer activity
    • Koehl G.E., Schlitt H.J., Geissler E.K. Rapamycin and tumor growth: Mechanism behind its anticancer activity. Transplant R 2005, 19:20-31.
    • (2005) Transplant R , vol.19 , pp. 20-31
    • Koehl, G.E.1    Schlitt, H.J.2    Geissler, E.K.3
  • 20
    • 34547130295 scopus 로고    scopus 로고
    • RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model
    • Mabuchi S., Altomare D.A., Cheung M., et al. RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model. Clin Cancer Res 2007, 13:4261-4270.
    • (2007) Clin Cancer Res , vol.13 , pp. 4261-4270
    • Mabuchi, S.1    Altomare, D.A.2    Cheung, M.3
  • 21
    • 0031740494 scopus 로고    scopus 로고
    • World Health Organization/International Society of Urological Pathology Consensus Classification of Urothelial (transitional cell) neoplasms of the urinary bladder
    • Epstein J.I., Amim B.M., Reuter V.R., et al. World Health Organization/International Society of Urological Pathology Consensus Classification of Urothelial (transitional cell) neoplasms of the urinary bladder. Am J Surg Pathol 1998, 22:1435-1448.
    • (1998) Am J Surg Pathol , vol.22 , pp. 1435-1448
    • Epstein, J.I.1    Amim, B.M.2    Reuter, V.R.3
  • 22
    • 79951812607 scopus 로고    scopus 로고
    • Effects of bevacizumab on autocrine VEGF stimulation in bladder cancer cell lines
    • Videira P., Piteira A.R., Cabral M.G., et al. Effects of bevacizumab on autocrine VEGF stimulation in bladder cancer cell lines. Urol Int 2001, 86:95-101.
    • (2001) Urol Int , vol.86 , pp. 95-101
    • Videira, P.1    Piteira, A.R.2    Cabral, M.G.3
  • 23
    • 0842333193 scopus 로고    scopus 로고
    • Preclinical evaluation of gemcitabine/paclitaxel interactions in human bladder cancer lines
    • Perabo F.G.E., Lindner H., Schmidt D., et al. Preclinical evaluation of gemcitabine/paclitaxel interactions in human bladder cancer lines. Anticancer Res 2003, 23:4805-4814.
    • (2003) Anticancer Res , vol.23 , pp. 4805-4814
    • Perabo, F.G.E.1    Lindner, H.2    Schmidt, D.3
  • 24
    • 58649090201 scopus 로고    scopus 로고
    • Effect of sirolimus on urinary bladder cancer T24 cell line
    • Pinto-Leite R., Botelho P., Ribeiro E., et al. Effect of sirolimus on urinary bladder cancer T24 cell line. J Exp Clin Can Res 2009, 28:3.
    • (2009) J Exp Clin Can Res , vol.28 , pp. 3
    • Pinto-Leite, R.1    Botelho, P.2    Ribeiro, E.3
  • 25
    • 60549102667 scopus 로고    scopus 로고
    • Rapamycin inhibits in vitro growth and release of angiogenetic factors in human bladder bancer
    • Fechner G., Claβen K., Schmidt D., et al. Rapamycin inhibits in vitro growth and release of angiogenetic factors in human bladder bancer. Urology 2009, 73:665-668.
    • (2009) Urology , vol.73 , pp. 665-668
    • Fechner, G.1    Claβen, K.2    Schmidt, D.3
  • 26
    • 38949110712 scopus 로고    scopus 로고
    • Effects of the proteasome inhibitor bortezomib on gene expression profiles of pancreatic cancer cells
    • Tang Z.Y., Wu Y.L., Gao S.L., et al. Effects of the proteasome inhibitor bortezomib on gene expression profiles of pancreatic cancer cells. J Surg Res 2008, 145:111-123.
    • (2008) J Surg Res , vol.145 , pp. 111-123
    • Tang, Z.Y.1    Wu, Y.L.2    Gao, S.L.3
  • 27
    • 75749105837 scopus 로고    scopus 로고
    • Inhibition of mammalian target of rapamycin as a therapeutic strategy in the management of bladder cancer
    • Mansure J.J., Nassim R., Chevalier S., et al. Inhibition of mammalian target of rapamycin as a therapeutic strategy in the management of bladder cancer. Cancer Biol Ther 2009, 8:2339-2347.
    • (2009) Cancer Biol Ther , vol.8 , pp. 2339-2347
    • Mansure, J.J.1    Nassim, R.2    Chevalier, S.3
  • 28
    • 79957983577 scopus 로고    scopus 로고
    • Targeting the PI3K/Akt/mTOR pathway-beyond rapalogs
    • Markman B., Dienstmann R., Tabernero J. Targeting the PI3K/Akt/mTOR pathway-beyond rapalogs. Oncotarget 2010, 1:530-543.
    • (2010) Oncotarget , vol.1 , pp. 530-543
    • Markman, B.1    Dienstmann, R.2    Tabernero, J.3
  • 29
    • 79955505851 scopus 로고    scopus 로고
    • Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells
    • Chiong E., Lee I.-L., Dadbin A., et al. Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells. Clin Cancer Res 2011, 17:2863-2873.
    • (2011) Clin Cancer Res , vol.17 , pp. 2863-2873
    • Chiong, E.1    Lee, I.-L.2    Dadbin, A.3
  • 30
    • 78649676757 scopus 로고    scopus 로고
    • Hypoxia-inducible factor and mammalian target of rapamycin pathway markers in urothelial carcinoma of the bladder: Possible therapeutic implications
    • Tickoo S., Satish K., Milowsky M.I., et al. Hypoxia-inducible factor and mammalian target of rapamycin pathway markers in urothelial carcinoma of the bladder: Possible therapeutic implications. BJU Int 2011, 107:844-849.
    • (2011) BJU Int , vol.107 , pp. 844-849
    • Tickoo, S.1    Satish, K.2    Milowsky, M.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.