Implantable cardioverter-defibrillators in lamin A/C mutation carriers with cardiac conduction disorders

Heart Rhythm

Volumn 10, Issue 10, 2013, Pages 1492-1498

  Anselme, Frédéric ^a   Moubarak, Ghassan ^a   Savouré, Arnaud ^a   Godin, Bénédicte ^a   Borz, Bogdan ^a   Drouin Garraud, Valérie ^a   Gay, Arnaud ^a  

^a ROUEN UNIVERSITY HOSPITAL   (France)

Author keywords

Conductiondisturbances; Implantablecardioverter defibrillator; Lamin A Cgene; Suddencardiacdeath; Ventricular arrhythmias

Indexed keywords

LAMIN A; LAMIN C;

ADULT; ARTICLE; ATRIOVENTRICULAR BLOCK; ATRIOVENTRICULAR CONDUCTION; BRADYCARDIA; CLINICAL ARTICLE; CLINICAL EVALUATION; FEMALE; FOLLOW UP; GENE MUTATION; HEART ATRIOVENTRICULAR NODE; HEART ATRIUM FIBRILLATION; HEART LEFT BUNDLE BRANCH BLOCK; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE CONDUCTION DISTURBANCE; HEART PACING; HEART VENTRICLE TACHYCARDIA; HUMAN; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR; MALE; OBSERVATIONAL STUDY; PHENOTYPE; PR INTERVAL; PRIORITY JOURNAL; PROSPECTIVE STUDY; SINUS NODE DISEASE;

ANTITACHYCARDIA PACING; ATP; ATRIOVENTRICULAR BLOCK; AVB; CONDUCTION DISTURBANCES; DCM; DILATED CARDIOMYOPATHY; ICD; IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR; LAMIN A/C GENE; LBBB; LEFT BUNDLE BRANCH BLOCK; LEFT VENTRICULAR EJECTION FRACTION; LMNA; LVEF; NONSUSTAINED VENTRICULAR TACHYCARDIA; NSVT; SCD; SUDDEN CARDIAC DEATH; VA; VENTRICULAR ARRHYTHMIAS; VENTRICULAR FIBRILLATION; VENTRICULAR TACHYCARDIA; VF; VT;

ADULT; ARRHYTHMIAS, CARDIAC; DEATH, SUDDEN, CARDIAC; DEFIBRILLATORS, IMPLANTABLE; FEMALE; FOLLOW-UP STUDIES; HEART CONDUCTION SYSTEM; HUMANS; LAMIN TYPE A; MALE; MIDDLE AGED; MUTATION; PROSPECTIVE STUDIES; TACHYCARDIA, VENTRICULAR; VENTRICULAR FIBRILLATION;

EID: 84884669962     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2013.06.020     Document Type: Article

References (21)

1. A. Mattout, T. Dechat, S.A. Adam, R.D. Goldman, and Y. Gruenbaum Nuclear lamins, diseases and aging Curr Opin Cell Biol 18 2006 335 341
2. G. Bonne, M.R. Di Barletta, and S. Varnous Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy Nat Genet 21 1999 285 288
3. A. De Sandre-Giovannoli, R. Bernard, and P. Cau Lamin a truncation in Hutchinson-Gilford progeria Science 300 2003 2055
4. A. De Sandre-Giovannoli, M. Chaouch, and S. Kozlov Homozygous defects in LMNA, encoding lamin A/C nuclear-envelope proteins, cause autosomal recessive axonal neuropathy in human (Charcot-Marie-Tooth disorder type 2) and mouse Am J Hum Genet 70 2002 726 736
5. S. Shackleton, D.J. Lloyd, and S.N. Jackson LMNA, encoding lamin A/C, is mutated in partial lipodystrophy Nat Genet 24 2000 153 156
6. H.M. Becane, G. Bonne, and S. Varnous High incidence of sudden death with conduction system and myocardial disease due to lamins A and C gene mutation Pacing Clin Electrophysiol 23 2000 1661 1666
7. D. Fatkin, C. MacRae, and T. Sasaki Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease N Engl J Med 341 1999 1715 1724
8. S. Karkkainen, T. Helio, and R. Miettinen A novel mutation, Ser143Pro, in the lamin A/C gene is common in Finnish patients with familial dilated cardiomyopathy Eur Heart J 25 2004 885 893
9. T. Sanna, A. Dello Russo, and D. Toniolo Cardiac features of Emery-Dreifuss muscular dystrophy caused by lamin A/C gene mutations Eur Heart J 24 2003 2227 2236
10. M.R. Taylor, P.R. Fain, and G. Sinagra Natural history of dilated cardiomyopathy due to lamin A/C gene mutations J Am Coll Cardiol 41 2003 771 780
11. J.H. van Berlo, W.G. de Voogt, and A.J. van der Kooi Meta-analysis of clinical characteristics of 299 carriers of LMNA gene mutations: do lamin A/C mutations portend a high risk of sudden death? J Mol Med (Berl) 83 2005 79 83
12. M. Pasotti, C. Klersy, and A. Pilotto Long-term outcome and risk stratification in dilated cardiolaminopathies J Am Coll Cardiol 52 2008 1250 1260
13. I.A. van Rijsingen, E. Arbustini, and P.M. Elliott Risk factors for malignant ventricular arrhythmias in lamin A/C mutation carriers a European cohort study J Am Coll Cardiol 59 2012 493 500
14. C. Meune, J.H. Van Berlo, F. Anselme, G. Bonne, Y.M. Pinto, and D. Duboc Primary prevention of sudden death in patients with lamin A/C gene mutations N Engl J Med 354 2006 209 210
15. J.P. van Tintelen, R.A. Tio, and W.S. Kerstjens-Frederikse Severe myocardial fibrosis caused by a deletion of the 5′ end of the lamin A/C gene J Am Coll Cardiol 49 2007 2430 2439
16. M. Holmstrom, S. Kivisto, and T. Helio Late gadolinium enhanced cardiovascular magnetic resonance of lamin A/C gene mutation related dilated cardiomyopathy J Cardiovasc Magn Reson 13 2011 30
17. K.H. Schreiber, and B.K. Kennedy When lamins go bad: nuclear structure and disease Cell 152 2013 1365 1375
18. C.M. Wolf, L. Wang, and R. Alcalai Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease J Mol Cell Cardiol 44 2008 293 303
19. R.L. Frock, S.C. Chen, and D.F. Da Cardiomyocyte-specific expression of lamin a improves cardiac function in Lmna-/- mice PLoS One 7 2012 e42918
20. J.P. Daubert, W. Zareba, and D.S. Cannom Inappropriate implantable cardioverter-defibrillator shocks in MADIT II: frequency, mechanisms, predictors, and survival impact J Am Coll Cardiol 51 2008 1357 1365
21. A.J. Moss, C. Schuger, and C.A. Beck Reduction in inappropriate therapy and mortality through ICD programming N Engl J Med 367 2012 2275 2283