Risk Factors and Outcomes for Late Presentation for HIV-Positive Persons in Europe: Results from the Collaboration of Observational HIV Epidemiological Research Europe Study (COHERE)

PLoS Medicine

Volumn 10, Issue 9, 2013, Pages

  Mocroft, Amanda ^a,g   Lundgren, Jens ^g   Sabin, Miriam Lewis ^b   D'Arminio Monforte, Antonella ^d,g   Brockmeyer, Norbert ^e,g   Casabona, Jordi ^f,g   Castagna, Antonella ^g   Costagliola, Dominique ^g,h,i   Dabis, François ^g   de Wit, Stephane ^g   Fätkenheuer, Gerd ^g,l   Furrer, Hansjakob ^g,m   Johnson, Anne ^g   Lazanas, Mario ^g   Leport, Catherine ^g,i,o   Moreno, Santiago ^g,p   Obel, Niels ^c,g   Post, Frank ^g   Reekie, Joanne ^a,g,r   Reiss, Peter ^g,s,t   Sabin, Caroline ^a,g   Skaletz Rorowski, Adriane ^e,g   Suarez Lozano, Ignacio ^u   Torti, Carlo ^g,v,w   Warszawski, Josiane ^g,x   Zangerle, Robert ^g,y   Fabre Colin, Céline ^g,i,j   Kjaer, Jesper ^b,g   Chene, Genevieve ^g,i,j   Grarup, Jesper ^b,g   Kirk, Ole ^b,c,g   Sabin, Miriam ^g   Suarez Loano, Ignacio ^g   Touloumi, Giota ^g   Meyer, Laurence ^g   Krause, Murielle Mary ^g   Ghosn, Jade ^g   de Wolf, Frank ^g   Prins, Maria ^g   Bucher, Heiner ^g   Gibb, Diana ^g   Hamouda, Osamah ^g   Bartmeyer, Barbara ^g   Del Amo, Julia ^g   Thorne, Claire ^g   Stephan, Christoph ^g   Pérez Hoyos, Santiago ^g   Noguera Julian, Antoni ^g   Antinori, Andrea ^g   Ramos, José ^g   Battegay, Manuel ^g   Rauch, Andri ^g   Mussini, Cristina ^g   Tookey, Pat ^g   Miró, Jose M ^g   Goetghebuer, Tessa ^g   Teira, Ramon ^g   Garrido, Myriam ^g   Judd, Ali ^g   Haerry, David ^g   Weller, Ian ^g   Schwimmer, Christine ^g   Termote, Monique ^g   Touzeau, Guillaume ^g   Campbell, Maria ^g   Friis Møller, Nina ^g   Bohlius, Julia ^g   Bouteloup, Vincent ^g   Cozzi Lepri, Alessandro ^g   Dorrucci, Maria ^g   Egger, Matthias ^g   Engsig, Frederik ^g   Lambotte, Olivier ^g   Lewden, Charlotte ^g   Lodwick, Rebecca ^g   Matheron, Sophie ^g   Miro, Jose ^g   Paredes, Roger ^g   Phillips, Andrew ^g   Puoti, Massimo ^g   Scherrer, Alexandra ^g   Smit, Colette ^g   Sterne, Jonathan ^g   Thiebaut, Rodolphe ^g   von Wyl, Viktor ^g   Wittkop, Linda ^g   more..

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c Rigshospitalet   (Denmark)

^d UNIVERSITY OF MILAN   (Italy)

^e RUHR UNIVERSITY BOCHUM   (Germany)

^f CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^g Department of Infectious Diseases IRCCS San Raffaele ^*

^h SORBONNE UNIVERSITÉ   (France)

ⁱ INSERM   (France)

^j UNIVERSITÉ DE BORDEAUX   (France)

^k SAINT PIERRE UNIVERSITY HOSPITAL   (Belgium)

^l UNIVERSITY OF COLOGNE   (Germany)

^m UNIVERSITY OF BERN   (Switzerland)

ⁿ RED CROSS HOSPITAL   (Greece)

^o UNIVERSITÉ PARIS DESCARTES   (France)

^p HOSPITAL RAMÓN Y CAJAL   (Spain)

^q KING'S COLLEGE LONDON   (United Kingdom)

^r UNIVERSITY OF NEW SOUTH WALES   (Australia)

^s ACADEMIC MEDICAL CENTER   (Netherlands)

^t STICHTING HIV MONITORING   (Netherlands)

^u Servicio de Cardiología   (Spain)

^v SPEDALI CIVILI   (Italy)

^w UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^x CENTRE FOR RESEARCH IN EPIDEMIOLOGY AND POPULATION HEALTH   (France)

^y INNSBRUCK MEDICAL UNIVERSITY   (Austria)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADOLESCENT; ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; CYTOMEGALOVIRUS; EASTERN EUROPE; ESOPHAGUS CANDIDIASIS; FEMALE; FOLLOW UP; HETEROSEXUAL FEMALE; HETEROSEXUAL MALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTRAVENOUS DRUG ABUSE; MALE; MALE HOMOSEXUAL; MORTALITY; OUTCOME ASSESSMENT; PNEUMONIA; RISK FACTOR; SENESCENCE; SOUTHERN EUROPE;

CD4 LYMPHOCYTE COUNT; COOPERATIVE BEHAVIOR; DISEASE PROGRESSION; EUROPE; FEMALE; HIV INFECTIONS; HIV SEROPOSITIVITY; HUMANS; INCIDENCE; MALE; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SUBSTANCE ABUSE, INTRAVENOUS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84884627659     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001510     Document Type: Article

References (37)

1. Girardi E, Aloisi MS, Arici C, Pezzotti P, Serraino D, et al. (2004) Delayed presentation and late testing for HIV: demographic and behavioral risk factors in a multicenter study in Italy. J Acquir Immune Defic Syndr 36: 951-959.
2. Antinori A, Coenen T, Costagiola D, Dedes N, Ellefson M, et al. (2011) Late presentation of HIV infection: a consensus definition. HIV Med 12: 61-64.
3. World Health Organization (2010) Antiretroviral therapy for HIV infection in adults and adolescents: recommendations for a public health approach.- 2010 revision. Available: http://whqlibdoc.who.int/publications/2010/9789241599764_eng.pdf. Accessed 23 July 2013.
4. Battegay M, Fluckiger U, Hirschel B, Furrer H, (2007) Late presentation of HIV-infected individuals. Antivir Ther 12: 841-851.
5. Sabin CA, Smith CJ, Gumley H, Murphy G, Lampe FC, et al. (2004) Late presenters in the era of highly active antiretroviral therapy: uptake of and responses to antiretroviral therapy. AIDS 18: 2145-2151.
6. Lanoy E, Mary-Krause M, Tattevin P, Perbost I, Poizot-Martin I, et al. (2007) Frequency, determinants and consequences of delayed access to care for HIV infection in France. Antivir Ther 12: 89-96.
7. Quinn TC, Wawer MJ, Sewankambo N, Serwadda D, Li C, et al. (2000) Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group. N Engl J Med 342: 921-929.
8. European Centre for Disease Prevention and Control. (2010) HIV testing: increasing uptake and effectiveness in the European Union. Available: http://www.ecdc.europa.eu/en/publications/Publications/101129_GUI_HIV_testing.pdf. Accessed 23 July 2013.
9. Krentz HB, Gill J, (2010) Despite CD4 cell count rebound the higher initial costs of medical care for HIV-infected patients persist 5 years after presentation with CD4 cell counts less than 350 mul. AIDS 24: 2750-2753.
10. Fleishman JA, Yehia BR, Moore RD, Gebo KA, (2010) The economic burden of late entry into medical care for patients with HIV infection. Med Care 48: 1071-1079.
11. Deblonde J, De KP, Hamers FF, Fontaine J, Luchters S, et al. (2010) Barriers to HIV testing in Europe: a systematic review. Eur J Public Health 20: 422-432.
12. Yazdanpanah Y, Lange J, Gerstoft J, Cairns G, (2010) Earlier testing for HIV-how do we prevent late presentation? Antivir Ther 15 Suppl 1: 17-24.
13. Kjaer J, Ledergerber B, (2004) HIV cohort collaborations: proposal for harmonization of data exchange. Antivir Ther 9: 631-633.
14. Zoufaly A, van der HM, Marcus U, Hoffmann C, Stellbrink H, et al. (2012) Late presentation for HIV diagnosis and care in Germany. HIV Med 13: 172-181.
15. d'Arminio MA, Cozzi-Lepri A, Girardi E, Castagna A, Mussini C, et al. (2011) Late presenters in new HIV diagnoses from an Italian cohort of HIV-infected patients: prevalence and clinical outcome. Antivir Ther 16: 1103-1112.
16. Camoni L, Raimondo M, Regine V, Salfa MC, Suligoi B, (2013) Late presenters among persons with a new HIV diagnosis in Italy, 2010-2011. BMC Public Health 13: 281.
17. Vives N, Carnicer-Pont D, Garcia de OP, Camps N, Esteve A, et al. (2012) Factors associated with late presentation of HIV infection in Catalonia, Spain. Int J STD AIDS 23: 475-480.
18. Helleberg M, Engsig FN, Kronborg G, Laursen AL, Pedersen G, et al. (2012) Late presenters, repeated testing, and missed opportunities in a Danish nationwide HIV cohort. Scand J Infect Dis 44: 282-288.
19. Ndiaye B, Salleron J, Vincent A, Bataille P, Bonnevie F, et al. (2011) Factors associated with presentation to care with advanced HIV disease in Brussels and Northern France: 1997-2007. BMC Infect Dis 11: 11.
20. European Centre for Disease Prevention and Control/WHO RegionalOffice for Europe (2009) HIV/AIDS surveillance in Europe 2009. Available: http://www.ecdc.europa.eu/en/publications/publications/101129_sur_hiv_2009.pdf. Accessed 23 July 2013.
21. World Health Organization (2007) Guidance on provider-initiated HIV testing and counselling in health facilities. Available: http://whqlibdoc.who.int/publications/2007/9789241595568_eng.pdf. Accessed 23 July 2013.
22. de Olalla PG, Manzardo C, Sambeat MA, Ocana I, Knobel H, et al. (2011) Epidemiological characteristics and predictors of late presentation of HIV infection in Barcelona (Spain) during the period 2001-2009. AIDS Res Ther 8: 22.
23. Castilla J, Sobrino P, De La Fuente L, Noguer I, Guerra L, et al. (2002) Late diagnosis of HIV infection in the era of highly active antiretroviral therapy: consequences for AIDS incidence. AIDS 16: 1945-1951.
24. Couturier E, Schwoebel V, Michon C, Hubert JB, Delmas MC, et al. (1998) Determinants of delayed diagnosis of HIV infection in France, 1993-1995. AIDS 12: 795-800.
25. Mathers BM, Degenhardt L, Ali H, Wiessing L, Hickman M, et al. (2010) HIV prevention, treatment, and care services for people who inject drugs: a systematic review of global, regional, and national coverage. Lancet 375: 1014-1028.
26. Dickson N, McAllister S, Sharples K, Paul C, (2012) Late presentation of HIV infection among adults in New Zealand: 2005-2010. HIV Med 13: 182-189.
27. Sullivan AK, Raben D, Reekie J, Rayment M, Mocroft A, et al. (2013) Feasibility and effectiveness of indicator condition-guided testing for HIV: results from HIDES I (HIV Indicator Diseases across Europe Study). PLoS One 8: e52845 doi:10.1371/journal.pone.0052845.
28. Chadborn TR, Delpech VC, Sabin CA, Sinka K, Evans BG, (2006) The late diagnosis and consequent short-term mortality of HIV-infected heterosexuals (England and Wales, 2000-2004). AIDS 20: 2371-2379.
29. Samet JH, Freedberg KA, Stein MD, Lewis R, Savetsky J, et al. (1998) Trillion virion delay: time from testing positive for HIV to presentation for primary care. Arch Intern Med 158: 734-740.
30. Delpierre C, Lauwers-Cances V, Pugliese P, Poizot-Martin I, Billaud E, et al. (2008) Characteristics trends, mortality and morbidity in persons newly diagnosed HIV positive during the last decade: the profile of new HIV diagnosed people. Eur J Public Health 18: 345-347.
31. Reekie J, Kowalska JD, Karpov I, Rockstroh J, Karlsson A, et al. (2012) Regional differences in AIDS and non-AIDS related mortality in HIV-positive individuals across Europe and Argentina: the EuroSIDA study. PLoS One 7: e41673 doi:10.1371/journal.pone.0041673.
32. Girardi E, Sabin CA, Monforte AD, (2007) Late diagnosis of HIV infection: epidemiological features, consequences and strategies to encourage earlier testing. J Acquir Immune Defic Syndr 46 Suppl 1: S3-S8.
33. Jolley E, Rhodes T, Platt L, Hope V, Latypov A, et al. (2012) HIV among people who inject drugs in Central and Eastern Europe and Central Asia: a systematic review with implications for policy. BMJ Open 2.
34. Likatavicius G, van de Laar MJ (2011) HIV infection and AIDS in the European Union and European Economic Area, 2010. Euro Surveill 16. Available: http://www.eurosurveillance.org/images/dynamic/EE/V16N48/art20030.pdf. Accessed 23 July 2013.
35. Global report: UNAIDS report on the global AIDS epidemic (2012). Available: http://www.unaids.org/en/media/unaids/contentassets/documents/epidemiology/2012/gr2012/20121120_UNAIDS_Global_Report_2012_en.pdf. Accessed 23 July 2013.
36. Johnson M, Sabin C, Girardi E, (2010) Definition and epidemiology of late presentation in Europe. Antivir Ther 15 Suppl 1: 3-8.
37. Turner BJ, Cunningham WE, Duan N, Andersen RM, Shapiro MF, et al. (2000) Delayed medical care after diagnosis in a US national probability sample of persons infected with human immunodeficiency virus. Arch Intern Med 160: 2614-2622.