-
1
-
-
0036090417
-
Insulin and leptin combine additively to reduce food intake and body weight in rats
-
Air EL, Benoit SC, Clegg DJ et al (2002) Insulin and leptin combine additively to reduce food intake and body weight in rats. Endocrinology 143: 2449-2452
-
(2002)
Endocrinology
, vol.143
, pp. 2449-2452
-
-
Air, E.L.1
Benoit, S.C.2
Clegg, D.J.3
-
2
-
-
50749118593
-
Insulin its chemistry and physiology lab
-
Banting F, Best C (1922) Insulin its chemistry and physiology lab. Clin Med 7:251-266
-
(1922)
Clin Med
, vol.7
, pp. 251-266
-
-
Banting, F.1
Best, C.2
-
4
-
-
78751485383
-
Intranasal insulin enhances postprandial thermogenesis and lowers postprandial serum insulin levels in healthy men
-
Benedict C, Brede S, Schioth HB et al (2011) Intranasal insulin enhances postprandial thermogenesis and lowers postprandial serum insulin levels in healthy men. Diabetes 60:114-118
-
(2011)
Diabetes
, vol.60
, pp. 114-118
-
-
Benedict, C.1
Brede, S.2
Schioth, H.B.3
-
5
-
-
78751706599
-
Intranasal insulin as a therapeutic option in the treatment of cognitive impairments
-
Benedict C, Frey WH II, Schioth HB et al (2011) Intranasal insulin as a therapeutic option in the treatment of cognitive impairments. Exp Gerontol 46:112-115
-
(2011)
Exp Gerontol
, vol.46
, pp. 112-115
-
-
Benedict, C.1
Frey, W.H.I.I.2
Schioth, H.B.3
-
7
-
-
33845695894
-
Intranasal insulin improves memory in humans: Superiority of insulin aspart
-
Benedict C, Hallschmid M, Schmitz K et al (2007) Intranasal insulin improves memory in humans: superiority of insulin aspart. Neuropsychopharmacology 32:239-243
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 239-243
-
-
Benedict, C.1
Hallschmid, M.2
Schmitz, K.3
-
8
-
-
85047698627
-
Sniffing neuropeptides: A transnasal approach to the human brain
-
Born J, Lange T, Kern W et al (2002) Sniffing neuropeptides: a transnasal approach to the human brain. Nat Neurosci 5:514-516
-
(2002)
Nat Neurosci
, vol.5
, pp. 514-516
-
-
Born, J.1
Lange, T.2
Kern, W.3
-
9
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
Bruning JC, Gautam D, Burks DJ et al (2000) Role of brain insulin receptor in control of body weight and reproduction. Science 289:2122-2125
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Bruning, J.C.1
Gautam, D.2
Burks, D.J.3
-
10
-
-
84855613853
-
Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: A pilot clinical trial
-
Craft S, Baker LD, Montine TJ et al (2012) Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial. Arch Neurol 69:29-38
-
(2012)
Arch Neurol
, vol.69
, pp. 29-38
-
-
Craft, S.1
Baker, L.D.2
Montine, T.J.3
-
11
-
-
0031907459
-
Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein e genotype
-
Craft S, Peskind E, Schwartz MW et al (1998) Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology 50:164-168
-
(1998)
Neurology
, vol.50
, pp. 164-168
-
-
Craft, S.1
Peskind, E.2
Schwartz, M.W.3
-
12
-
-
60549084867
-
Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Abeta oligomers
-
De Felice FG, Vieira MN, Bomfim TR et al (2009) Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. Proc Natl Acad Sci U S A 106:1971-1976
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1971-1976
-
-
De Felice, F.G.1
Vieira, M.N.2
Bomfim, T.R.3
-
13
-
-
77949833508
-
Intranasal delivery to the central nervous system: Mechanisms and experimental considerations
-
Dhuria SV, Hanson LR, Frey WH II (2010) Intranasal delivery to the central nervous system: mechanisms and experimental considerations. J Pharm Sci 99:1654-1673
-
(2010)
J Pharm Sci
, vol.99
, pp. 1654-1673
-
-
Dhuria, S.V.1
Hanson, L.R.2
Frey, W.H.I.I.3
-
14
-
-
79952444478
-
No effect of single-dose intranasal insulin treatment on verbal memory and sustained attention in patients with schizophrenia
-
Fan X, Copeland PM, Liu EY et al (2011) No effect of single-dose intranasal insulin treatment on verbal memory and sustained attention in patients with schizophrenia. J Clin Psychopharmacol 31: 231-234
-
(2011)
J Clin Psychopharmacol
, vol.31
, pp. 231-234
-
-
Fan, X.1
Copeland, P.M.2
Liu, E.Y.3
-
15
-
-
82355192272
-
The Abeta oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease
-
Ferreira ST, Klein WL (2011) The Abeta oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease. Neurobiol Learn Mem 96:529-543
-
(2011)
Neurobiol Learn Mem
, vol.96
, pp. 529-543
-
-
Ferreira, S.T.1
Klein, W.L.2
-
16
-
-
0037131025
-
New insights into neuron-glia communication
-
Fields RD, Stevens-Graham B (2002) New insights into neuron-glia communication. Science 298:556-562
-
(2002)
Science
, vol.298
, pp. 556-562
-
-
Fields, R.D.1
Stevens-Graham, B.2
-
17
-
-
0037303635
-
Brain insulin: Regulation, mechanisms of action and functions
-
Gerozissis K (2003) Brain insulin: regulation, mechanisms of action and functions. Cell Mol Neurobiol 23:1-25
-
(2003)
Cell Mol Neurobiol
, vol.23
, pp. 1-25
-
-
Gerozissis, K.1
-
18
-
-
0034843738
-
The emerging role of glutamate in the pathophysiology and treatment of schizophrenia
-
Goff DC, Coyle JT (2001) The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. Am J Psychiatry 158:1367-1377
-
(2001)
Am J Psychiatry
, vol.158
, pp. 1367-1377
-
-
Goff, D.C.1
Coyle, J.T.2
-
19
-
-
76149103529
-
Insulin modulates food-related activity in the central nervous system
-
Guthoff M, Grichisch Y, Canova C et al (2010) Insulin modulates food-related activity in the central nervous system. J Clin Endocrinol Metab 95: 748-755
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 748-755
-
-
Guthoff, M.1
Grichisch, Y.2
Canova, C.3
-
20
-
-
79955935863
-
The insulin-mediated modulation of visually evoked magnetic fields is reduced in obese subjects
-
Guthoff M, Stingl KT, Tschritter O et al (2011) The insulin-mediated modulation of visually evoked magnetic fields is reduced in obese subjects. PLoS One 6:e19482
-
(2011)
PLoS One
, vol.6
-
-
Guthoff, M.1
Stingl, K.T.2
Tschritter, O.3
-
21
-
-
39449093463
-
Obese men respond to cognitive but not to catabolic brain insulin signaling
-
Hallschmid M, Benedict C, Schultes B et al (2008) Obese men respond to cognitive but not to catabolic brain insulin signaling. Int J Obes (Lond) 32:275-282
-
(2008)
Int J Obes (Lond)
, vol.32
, pp. 275-282
-
-
Hallschmid, M.1
Benedict, C.2
Schultes, B.3
-
22
-
-
7044241101
-
Intranasal insulin reduces body fat in men but not in women
-
Hallschmid M, Benedict C, Schultes B et al (2004) Intranasal insulin reduces body fat in men but not in women. Diabetes 53:3024-3029
-
(2004)
Diabetes
, vol.53
, pp. 3024-3029
-
-
Hallschmid, M.1
Benedict, C.2
Schultes, B.3
-
23
-
-
84859526987
-
Postprandial administration of intranasal insulin intensifies satiety and reduces intake of palatable snacks in women
-
Hallschmid M, Higgs S, Thienel M et al (2012) Postprandial administration of intranasal insulin intensifies satiety and reduces intake of palatable snacks in women. Diabetes 61:782-789
-
(2012)
Diabetes
, vol.61
, pp. 782-789
-
-
Hallschmid, M.1
Higgs, S.2
Thienel, M.3
-
24
-
-
70349847831
-
Central nervous insulin resistance: A promising target in the treatment of metabolic and cognitive disorders?
-
Hallschmid M, Schultes B (2009) Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders? Diabetologia 52:2264-2269
-
(2009)
Diabetologia
, vol.52
, pp. 2264-2269
-
-
Hallschmid, M.1
Schultes, B.2
-
25
-
-
4344595379
-
Transcortical direct current potential shift reflects immediate signaling of systemic insulin to the human brain
-
Hallschmid M, Schultes B, Marshall L et al (2004) Transcortical direct current potential shift reflects immediate signaling of systemic insulin to the human brain. Diabetes 53:2202-2208
-
(2004)
Diabetes
, vol.53
, pp. 2202-2208
-
-
Hallschmid, M.1
Schultes, B.2
Marshall, L.3
-
27
-
-
84865522894
-
Intranasal insulin suppresses food intake via enhancement of brain energy levels in humans
-
Jauch-Chara K, Friedrich A, Rezmer M et al (2012) Intranasal insulin suppresses food intake via enhancement of brain energy levels in humans. Diabetes 61(9):2261-2268
-
(2012)
Diabetes
, vol.61
, Issue.9
, pp. 2261-2268
-
-
Jauch-Chara, K.1
Friedrich, A.2
Rezmer, M.3
-
28
-
-
0033857975
-
Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs
-
Kaiyala KJ, Prigeon RL, Kahn SE et al (2000) Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs. Diabetes 49:1525-1533
-
(2000)
Diabetes
, vol.49
, pp. 1525-1533
-
-
Kaiyala, K.J.1
Prigeon, R.L.2
Kahn, S.E.3
-
29
-
-
34848848771
-
Low cerebrospinal fluid insulin levels in obese humans
-
Kern W, Benedict C, Schultes B et al (2006) Low cerebrospinal fluid insulin levels in obese humans. Diabetologia 49:2790-2792
-
(2006)
Diabetologia
, vol.49
, pp. 2790-2792
-
-
Kern, W.1
Benedict, C.2
Schultes, B.3
-
30
-
-
0025612094
-
Localization of insulin receptor mRNA in rat brain by in situ hybridization
-
Marks JL, Porte D Jr, Stahl WL et al (1990) Localization of insulin receptor mRNA in rat brain by in situ hybridization. Endocrinology 127:3234-3236
-
(1990)
Endocrinology
, vol.127
, pp. 3234-3236
-
-
Marks, J.L.1
Porte Jr., D.2
Stahl, W.L.3
-
31
-
-
64649097658
-
FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease
-
Mosconi L, Mistur R, Switalski R et al (2009) FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease. Eur J Nucl Med Mol Imaging 36:811-822
-
(2009)
Eur J Nucl Med Mol Imaging
, vol.36
, pp. 811-822
-
-
Mosconi, L.1
Mistur, R.2
Switalski, R.3
-
32
-
-
84857034930
-
Intranasal administration of insulin to the brain impacts cognitive function and peripheral metabolism
-
Ott V, Benedict C, Schultes B et al (2012) Intranasal administration of insulin to the brain impacts cognitive function and peripheral metabolism. Diabetes Obes Metab 14:214-221
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 214-221
-
-
Ott, V.1
Benedict, C.2
Schultes, B.3
-
33
-
-
0034012731
-
Intracerebroventricular insulin enhances memory in a passive-avoidance task
-
Park CR, Seeley RJ, Craft S et al (2000) Intracerebroventricular insulin enhances memory in a passive-avoidance task. Physiol Behav 68:509-514
-
(2000)
Physiol Behav
, vol.68
, pp. 509-514
-
-
Park, C.R.1
Seeley, R.J.2
Craft, S.3
-
34
-
-
0037207060
-
Growth hormone-releasing hormone facilitates hypoglycemia-induced release of cortisol
-
Perras B, Schultes B, Schwaiger R et al (2002) Growth hormone-releasing hormone facilitates hypoglycemia-induced release of cortisol. Regul Pept 110:85-91
-
(2002)
Regul Pept
, vol.110
, pp. 85-91
-
-
Perras, B.1
Schultes, B.2
Schwaiger, R.3
-
35
-
-
40349091597
-
Intranasal insulin improves cognition and modulates beta-amyloid in early AD
-
Reger MA, Watson GS, Green PS et al (2008) Intranasal insulin improves cognition and modulates beta-amyloid in early AD. Neurology 70:440-448
-
(2008)
Neurology
, vol.70
, pp. 440-448
-
-
Reger, M.A.1
Watson, G.S.2
Green, P.S.3
-
36
-
-
84869089454
-
Intranasal delivery of insulin via the olfactory nerve pathway
-
Renner DB, Svitak AL, Gallus NJ et al (2012) Intranasal delivery of insulin via the olfactory nerve pathway. J Pharm Pharmacol 64:1709-1714
-
(2012)
J Pharm Pharmacol
, vol.64
, pp. 1709-1714
-
-
Renner, D.B.1
Svitak, A.L.2
Gallus, N.J.3
-
37
-
-
0020286297
-
Evidence for the presence of specific receptors for insulin-like growth factors 1 (IGE-1) and 2 (IGF-2) and insulin throughout the adult human brain
-
Sara VR, Hall K, Von Holtz H et al (1982) Evidence for the presence of specific receptors for insulin-like growth factors 1 (IGE-1) and 2 (IGF-2) and insulin throughout the adult human brain. Neurosci Lett 34:39-44
-
(1982)
Neurosci Lett
, vol.34
, pp. 39-44
-
-
Sara, V.R.1
Hall, K.2
Von Holtz, H.3
-
38
-
-
84868157564
-
Brain insulin signaling and Alzheimer's disease: Current evidence and future directions
-
Schioth HB, Craft S, Brooks SJ et al (2011) Brain insulin signaling and Alzheimer's disease: current evidence and future directions. Mol Neurobiol
-
(2011)
Mol Neurobiol
-
-
Schioth, H.B.1
Craft, S.2
Brooks, S.J.3
-
39
-
-
80052554457
-
Unconditioned and conditioned effects of intranasally administered insulin vs placebo in healthy men: A randomised controlled trial
-
Stockhorst U, De Fries D, Steingrueber HJ et al (2011) Unconditioned and conditioned effects of intranasally administered insulin vs placebo in healthy men: a randomised controlled trial. Diabetologia 54:1502-1506
-
(2011)
Diabetologia
, vol.54
, pp. 1502-1506
-
-
Stockhorst, U.1
De Fries, D.2
Steingrueber, H.J.3
-
40
-
-
0029026040
-
Quantitative analysis of the olfactory pathway for drug delivery to the brain
-
Thorne RG, Emory CR, Ala TA et al (1995) Quantitative analysis of the olfactory pathway for drug delivery to the brain. Brain Res 692:278-282
-
(1995)
Brain Res
, vol.692
, pp. 278-282
-
-
Thorne, R.G.1
Emory, C.R.2
Ala, T.A.3
-
41
-
-
33747058235
-
The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: A magnetoencephalographic study
-
Tschritter O, Preissl H, Hennige AM et al (2006) The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: a magnetoencephalographic study. Proc Natl Acad Sci U S A 103:12103-12108
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 12103-12108
-
-
Tschritter, O.1
Preissl, H.2
Hennige, A.M.3
-
42
-
-
0020998384
-
Circumventricular organs: Receptors and mediators of direct peptide hormone action on brain
-
Van Houten M, Posner BI (1983) Circumventricular organs: receptors and mediators of direct peptide hormone action on brain. Adv Metab Disord 10:269-289
-
(1983)
Adv Metab Disord
, vol.10
, pp. 269-289
-
-
Van Houten, M.1
Posner, B.I.2
|