-
1
-
-
0037022840
-
Norepinephrine turnover is increased in suprabulbar subcortical brain regions and is related to whole-body sympathetic activity in human heart failure
-
doi: 10.1161/hc0902.105724
-
Aggarwal, A., Esler, M. D., Lambert, G. W., Hastings, J., Johnston, L., and Kaye, D. M. (2002). Norepinephrine turnover is increased in suprabulbar subcortical brain regions and is related to whole-body sympathetic activity in human heart failure. Circulation 105, 1031-1033. doi: 10.1161/hc0902.105724
-
(2002)
Circulation
, vol.105
, pp. 1031-1033
-
-
Aggarwal, A.1
Esler, M.D.2
Lambert, G.W.3
Hastings, J.4
Johnston, L.5
Kaye, D.M.6
-
2
-
-
0035312887
-
Evidence for functional presynaptic alpha-2 adrenoceptors and their down-regulation in human heart failure
-
doi: 10.1016/S0735-1097(01)01121-4
-
Aggarwal, A., Esler, M. D., Socratous, F., and Kaye, D. M. (2001). Evidence for functional presynaptic alpha-2 adrenoceptors and their down-regulation in human heart failure. J. Am. Coll. Cardiol. 37, 1246-1251. doi: 10.1016/S0735-1097(01)01121-4
-
(2001)
J. Am. Coll. Cardiol.
, vol.37
, pp. 1246-1251
-
-
Aggarwal, A.1
Esler, M.D.2
Socratous, F.3
Kaye, D.M.4
-
4
-
-
0026658663
-
The G-protein-coupled receptor kinases betaARK1 and betaARK2 are widely distributed at synapses in rat brain
-
Arriza, J. L., Dawson, T. M., Simerly, R. B., Martin, L. J., Caron, M. G., Snyder, S. H., et al. (1992). The G-protein-coupled receptor kinases betaARK1 and betaARK2 are widely distributed at synapses in rat brain. J. Neurosci. 12, 4045-4055.
-
(1992)
J. Neurosci.
, vol.12
, pp. 4045-4055
-
-
Arriza, J.L.1
Dawson, T.M.2
Simerly, R.B.3
Martin, L.J.4
Caron, M.G.5
Snyder, S.H.6
-
5
-
-
0034970928
-
The neuronal norepinephrine transporter in experimental heart failure: evidence for a post-transcriptional downregulation
-
doi: 10.1006/jmcc.2000.1319
-
Backs, J., Haunstetter, A., Gerber, S. H., Metz, J., Borst, M. M., Strasser, R. H., et al. (2001). The neuronal norepinephrine transporter in experimental heart failure: evidence for a post-transcriptional downregulation. J. Mol. Cell. Cardiol. 33, 461-472. doi: 10.1006/jmcc.2000.1319
-
(2001)
J. Mol. Cell. Cardiol.
, vol.33
, pp. 461-472
-
-
Backs, J.1
Haunstetter, A.2
Gerber, S.H.3
Metz, J.4
Borst, M.M.5
Strasser, R.H.6
-
6
-
-
0041765759
-
Differential control of adrenal and sympathetic catecholamine release by alpha2-adrenoceptor subtypes
-
doi: 10.1210/me.2003-0035
-
Brede, M., Nagy, G., Philipp, M., Sorensen, J. B., Lohse, M. J., and Hein, L. (2003). Differential control of adrenal and sympathetic catecholamine release by alpha2-adrenoceptor subtypes. Mol. Endocrinol. 17, 1640-1646. doi: 10.1210/me.2003-0035
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 1640-1646
-
-
Brede, M.1
Nagy, G.2
Philipp, M.3
Sorensen, J.B.4
Lohse, M.J.5
Hein, L.6
-
7
-
-
0037027480
-
Feedback inhibition of catecholamine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure
-
doi: 10.1161/01.CIR.0000036600.39600.66
-
Brede, M., Wiesmann, F., Jahns, R., Hadamek, K., Arnolt, C., Neubauer, S., et al. (2002). Feedback inhibition of catecholamine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure. Circulation 106, 2491-2496. doi: 10.1161/01.CIR.0000036600.39600.66
-
(2002)
Circulation
, vol.106
, pp. 2491-2496
-
-
Brede, M.1
Wiesmann, F.2
Jahns, R.3
Hadamek, K.4
Arnolt, C.5
Neubauer, S.6
-
8
-
-
0019982539
-
Decreased catecholamine sensitivity and β-adrenegic receptor density in failing human hearts
-
doi: 10.1056/NEJM198207223070401
-
Bristow, M. R., Ginsburg, R., Minobe, W., Cubicciotti, R., Sageman, W. S., Lurie, K., et al. (1982). Decreased catecholamine sensitivity and β-adrenegic receptor density in failing human hearts. N. Engl. J. Med. 307, 205-211. doi: 10.1056/NEJM198207223070401
-
(1982)
N. Engl. J. Med.
, vol.307
, pp. 205-211
-
-
Bristow, M.R.1
Ginsburg, R.2
Minobe, W.3
Cubicciotti, R.4
Sageman, W.S.5
Lurie, K.6
-
9
-
-
0022980843
-
β1-and β2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective β1-receptor down-regulation in heart failure
-
doi: 10.1161/01.RES.59.3.297
-
Bristow, M. R., Ginsburg, R., Umans, V., Fowler, M., Minobe, W., Rasmussen, R., et al. (1986). β1-and β2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective β1-receptor down-regulation in heart failure. Circ. Res. 59, 297-309. doi: 10.1161/01.RES.59.3.297
-
(1986)
Circ. Res.
, vol.59
, pp. 297-309
-
-
Bristow, M.R.1
Ginsburg, R.2
Umans, V.3
Fowler, M.4
Minobe, W.5
Rasmussen, R.6
-
10
-
-
0027819354
-
Beta-adrenoceptors in cardiac disease
-
doi: 10.1016/0163-7258(93)90030-H
-
Brodde, O. E. (1993). Beta-adrenoceptors in cardiac disease. Pharmacol. Ther. 60, 405-430. doi: 10.1016/0163-7258(93)90030-H
-
(1993)
Pharmacol. Ther.
, vol.60
, pp. 405-430
-
-
Brodde, O.E.1
-
11
-
-
0036839584
-
Abnormal cardiac function associated with sympathetic nervous system hyperactivity in mice
-
Brum, P. C., Kosek, J., Patterson, A., Bernstein, D., and Kobilka, B. (2002). Abnormal cardiac function associated with sympathetic nervous system hyperactivity in mice. Am. J. Physiol. Heart Circ. Physiol. 283, H1838-H1845.
-
(2002)
Am. J. Physiol. Heart Circ. Physiol.
, vol.283
-
-
Brum, P.C.1
Kosek, J.2
Patterson, A.3
Bernstein, D.4
Kobilka, B.5
-
12
-
-
0028183015
-
International union of pharmacology nomenclature of adrenoceptors
-
Bylund, D. B., Eikenberg, D. C., Hieble, J. P., Langer, S. Z., Lefkowitz, R. J., Minneman, K. P., et al. (1994). International union of pharmacology nomenclature of adrenoceptors. Pharmacol. Rev. 46, 121-136.
-
(1994)
Pharmacol. Rev.
, vol.46
, pp. 121-136
-
-
Bylund, D.B.1
Eikenberg, D.C.2
Hieble, J.P.3
Langer, S.Z.4
Lefkowitz, R.J.5
Minneman, K.P.6
-
13
-
-
0034623819
-
The β2-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through Gi-dependent coupling to phosphatidylinositol 3-kinase
-
doi: 10.1161/01.RES.87.12.1172
-
Chesley, A., Lundberg, M. S., Asai, T., Xiao, R. P., Ohtani, S., Lakatta, E. G., et al. (2000). The β2-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through Gi-dependent coupling to phosphatidylinositol 3-kinase. Circ. Res. 87, 1172-1179. doi: 10.1161/01.RES.87.12.1172
-
(2000)
Circ. Res.
, vol.87
, pp. 1172-1179
-
-
Chesley, A.1
Lundberg, M.S.2
Asai, T.3
Xiao, R.P.4
Ohtani, S.5
Lakatta, E.G.6
-
14
-
-
0022647639
-
New positive inotropic agents in the treatment of congestive heart failure
-
doi: 10.1056/NEJM198601303140506
-
Colucci, W. S., Wright, R. F., and Braunwald, E. (1986). New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. N. Engl. J. Med. 314, 290-299. doi: 10.1056/NEJM198601303140506
-
(1986)
Mechanisms of action and recent clinical developments. N. Engl. J. Med.
, vol.314
, pp. 290-299
-
-
Colucci, W.S.1
Wright, R.F.2
Braunwald, E.3
-
15
-
-
0032729995
-
Opposing effects of β1-and β2-aadrenergic receptors on cardiac myocyte apoptosis: role of a pertussis toxin-sensitive G protein
-
doi: 10.1161/01.CIR.100.22.2210
-
Communal, C., Singh, K., Sawyer, D. B., and Colucci, W. S. (1999). Opposing effects of β1-and β2-aadrenergic receptors on cardiac myocyte apoptosis: role of a pertussis toxin-sensitive G protein. Circulation 100, 2210-2212. doi: 10.1161/01.CIR.100.22.2210
-
(1999)
Circulation
, vol.100
, pp. 2210-2212
-
-
Communal, C.1
Singh, K.2
Sawyer, D.B.3
Colucci, W.S.4
-
16
-
-
0030613761
-
Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A
-
doi: 10.1038/36362
-
Daaka, Y., Luttrell, L. M., and Lefkowitz, R. J. (1997). Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A. Nature 390, 88-91. doi: 10.1038/36362
-
(1997)
Nature
, vol.390
, pp. 88-91
-
-
Daaka, Y.1
Luttrell, L.M.2
Lefkowitz, R.J.3
-
17
-
-
0037186480
-
Age-related changes in adrenergic neuroeffector transmission
-
doi: 10.1016/S1566-0702(01)00375-7
-
Docherty, J. R. (2002). Age-related changes in adrenergic neuroeffector transmission. Auton. Neurosci. 96, 8-12. doi: 10.1016/S1566-0702(01)00375-7
-
(2002)
Auton. Neurosci.
, vol.96
, pp. 8-12
-
-
Docherty, J.R.1
-
18
-
-
0033033440
-
Low- and high-level transgenic expression of β2-adrenergic receptors differentially affect cardiac hypertrophy and function in Gα q-overexpressing mice
-
doi: 10.1073/pnas.96.11.6400
-
Dorn, G. W. II., Tepe, N. M., Lorenz, J. N., Koch, W. J., and Liggett, S. B. (1999). Low- and high-level transgenic expression of β2-adrenergic receptors differentially affect cardiac hypertrophy and function in Gα q-overexpressing mice. Proc. Natl. Acad. Sci. U.S.A. 96, 6400-6405. doi: 10.1073/pnas.96.11.6400
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 6400-6405
-
-
Dorn, G.W.1
Tepe, N.M.2
Lorenz, J.N.3
Koch, W.J.4
Liggett, S.B.5
-
19
-
-
33845186121
-
Transgenic alpha1A-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival
-
doi: 10.1016/j.cardiores.2006.06.015
-
Du, X. J., Gao, X. M., Kiriazis, H., Moore, X. L., Ming, Z., Su, Y., et al. (2006). Transgenic alpha1A-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival. Cardiovasc. Res. 71, 735-743. doi: 10.1016/j.cardiores.2006.06.015
-
(2006)
Cardiovasc. Res.
, vol.71
, pp. 735-743
-
-
Du, X.J.1
Gao, X.M.2
Kiriazis, H.3
Moore, X.L.4
Ming, Z.5
Su, Y.6
-
20
-
-
0019508224
-
Relation of the renin-angiotensin-aldosterone system to clinical state in congestive heart failure
-
doi: 10.1161/01.CIR.63.3.645
-
Dzau, V. J., Colucci, W. S., Hollenberg, N. K., and Williams, G. H. (1981). Relation of the renin-angiotensin-aldosterone system to clinical state in congestive heart failure. Circulation 63, 645-651. doi: 10.1161/01.CIR.63.3.645
-
(1981)
Circulation
, vol.63
, pp. 645-651
-
-
Dzau, V.J.1
Colucci, W.S.2
Hollenberg, N.K.3
Williams, G.H.4
-
21
-
-
8344236658
-
Useful cell lines derived from the adrenal medulla
-
doi: 10.1016/j.mce.2003.02.001
-
Eaton, M. J., and Duplan, H. (2004). Useful cell lines derived from the adrenal medulla. Mol. Cell. Endocrinol. 228, 39-52. doi: 10.1016/j.mce.2003.02.001
-
(2004)
Mol. Cell. Endocrinol.
, vol.228
, pp. 39-52
-
-
Eaton, M.J.1
Duplan, H.2
-
22
-
-
0035101820
-
Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling
-
Ferguson, S. S. (2001). Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol. Rev. 53, 1-24.
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 1-24
-
-
Ferguson, S.S.1
-
23
-
-
0032189129
-
The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle
-
doi: 10.1172/JCI2191
-
Gauthier, C., Leblais, V., Kobzik, L., Trochu, J. N., Khandoudi, N., Bril, A., et al. (1998). The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle. J. Clin. Invest. 102, 1377-1384. doi: 10.1172/JCI2191
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1377-1384
-
-
Gauthier, C.1
Leblais, V.2
Kobzik, L.3
Trochu, J.N.4
Khandoudi, N.5
Bril, A.6
-
24
-
-
0033547241
-
Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission
-
doi: 10.1038/46040
-
Hein, L., Altman, J. D., and Kobilka, B. K. (1999). Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission. Nature 402, 181-184. doi: 10.1038/46040
-
(1999)
Nature
, vol.402
, pp. 181-184
-
-
Hein, L.1
Altman, J.D.2
Kobilka, B.K.3
-
25
-
-
23944432884
-
Neurohumoral pathways in heart failure with preserved systolic function
-
doi: 10.1016/j.pcad.2005.02.001
-
Hogg, K., and McMurray, J. (2005). Neurohumoral pathways in heart failure with preserved systolic function. Prog. Cardiovasc. Dis. 47, 357-366. doi: 10.1016/j.pcad.2005.02.001
-
(2005)
Prog. Cardiovasc. Dis.
, vol.47
, pp. 357-366
-
-
Hogg, K.1
McMurray, J.2
-
26
-
-
33847105534
-
An alpha1A-adrenergic extracellular signal-regulated kinase survival signaling pathway in cardiac myocytes
-
doi: 10.1161/CIRCULATIONAHA.106.664862
-
Huang, Y., Wright, C. D., Merkwan, C. L., Baye, N. L., Liang, Q., Simpson, P. C., et al. (2007). An alpha1A-adrenergic extracellular signal-regulated kinase survival signaling pathway in cardiac myocytes. Circulation 115, 763-772. doi: 10.1161/CIRCULATIONAHA.106.664862
-
(2007)
Circulation
, vol.115
, pp. 763-772
-
-
Huang, Y.1
Wright, C.D.2
Merkwan, C.L.3
Baye, N.L.4
Liang, Q.5
Simpson, P.C.6
-
27
-
-
16344370766
-
Sympathetic neuronal regulation of the heart in aging and heart failure
-
doi: 10.1016/j.cardiores.2005.02.012
-
Kaye, D., and Esler, M. (2005). Sympathetic neuronal regulation of the heart in aging and heart failure. Cardiovasc. Res. 66, 256-264. doi: 10.1016/j.cardiores.2005.02.012
-
(2005)
Cardiovasc. Res.
, vol.66
, pp. 256-264
-
-
Kaye, D.1
Esler, M.2
-
28
-
-
0027176441
-
The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy
-
Knowlton, K. U., Michel, M. C., Itani, M., Shubeita, H. E., Ishihara, K., Brown, J. H., et al. (1993). The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy. J. Biol. Chem. 268, 15374-15380.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15374-15380
-
-
Knowlton, K.U.1
Michel, M.C.2
Itani, M.3
Shubeita, H.E.4
Ishihara, K.5
Brown, J.H.6
-
29
-
-
0030798681
-
Sympathoinhibitory response to clonidine is blunted in patients with heart failure
-
doi: 10.1161/01.HYP.30.3.392
-
Lang, C. C., Stein, C. M., Nelson, R. A., He, H. B., Belas, F. J., Blair, I. A., et al. (1997). Sympathoinhibitory response to clonidine is blunted in patients with heart failure. Hypertension 30, 392-397. doi: 10.1161/01.HYP.30.3.392
-
(1997)
Hypertension
, vol.30
, pp. 392-397
-
-
Lang, C.C.1
Stein, C.M.2
Nelson, R.A.3
He, H.B.4
Belas, F.J.5
Blair, I.A.6
-
30
-
-
0037120971
-
Age-dependent changes of cardiac neuronal noradrenaline reuptake transporter (uptake1) in the human heart
-
doi: 10.1016/S0735-1097(02)02168-X
-
Leineweber, K., Wangemann, T., Giessler, C., Bruck, H., Dhein, S., Kostelka, M., et al. (2002). Age-dependent changes of cardiac neuronal noradrenaline reuptake transporter (uptake1) in the human heart. J. Am. Coll. Cardiol. 40, 1459. doi: 10.1016/S0735-1097(02)02168-X
-
(2002)
J. Am. Coll. Cardiol.
, vol.40
, pp. 1459
-
-
Leineweber, K.1
Wangemann, T.2
Giessler, C.3
Bruck, H.4
Dhein, S.5
Kostelka, M.6
-
31
-
-
0034636061
-
Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level
-
doi: 10.1161/01.CIR.101.14.1707
-
Liggett, S. B., Tepe, N. M., Lorenz, J. N., Canning, A. M., Jantz, T. D., Mitarai, S., et al. (2000). Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level. Circulation 101, 1707-1714. doi: 10.1161/01.CIR.101.14.1707
-
(2000)
Circulation
, vol.101
, pp. 1707-1714
-
-
Liggett, S.B.1
Tepe, N.M.2
Lorenz, J.N.3
Canning, A.M.4
Jantz, T.D.5
Mitarai, S.6
-
32
-
-
1242342716
-
Superoxide is involved in the central nervous system activation and sympathoexcitation of myocardial infarction induced heart failure
-
doi: 10.1161/01.RES.0000112964.40701.93
-
Lindley, T. E., Doobay, M., Sharma, R., and Davisson, R. (2004). Superoxide is involved in the central nervous system activation and sympathoexcitation of myocardial infarction induced heart failure. Circ. Res. 94, 402-409. doi: 10.1161/01.RES.0000112964.40701.93
-
(2004)
Circ. Res.
, vol.94
, pp. 402-409
-
-
Lindley, T.E.1
Doobay, M.2
Sharma, R.3
Davisson, R.4
-
33
-
-
0242637601
-
What is the role of beta-adrenergic signaling in heart failure?
-
Lohse, M. J., Engelhardt, S., and Eschenhagen, T. (2003). What is the role of beta-adrenergic signaling in heart failure? Circ. Res. 93, 896-906.
-
(2003)
Circ. Res.
, vol.93
, pp. 896-906
-
-
Lohse, M.J.1
Engelhardt, S.2
Eschenhagen, T.3
-
34
-
-
84865810509
-
Ischemic emergency? endothelial cells have their own "adrenaline shot" at hand
-
doi: 10.1161/HYPERTENSIONAHA.112.197020
-
Lymperopoulos, A. (2012). Ischemic emergency? endothelial cells have their own "adrenaline shot" at hand. Hypertension 60, 12-14. doi: 10.1161/HYPERTENSIONAHA.112.197020
-
(2012)
Hypertension
, vol.60
, pp. 12-14
-
-
Lymperopoulos, A.1
-
35
-
-
84856739717
-
Pharmacogenomics of the heptahelical receptor regulators G-protein-coupled receptor kinases and arrestins: the known and the unknown
-
doi: 10.2217/pgs.11.178
-
Lymperopoulos, A., and Bathgate, A. (2012). Pharmacogenomics of the heptahelical receptor regulators G-protein-coupled receptor kinases and arrestins: the known and the unknown. Pharmacogenomics 13, 323-341. doi: 10.2217/pgs.11.178
-
(2012)
Pharmacogenomics
, vol.13
, pp. 323-341
-
-
Lymperopoulos, A.1
Bathgate, A.2
-
36
-
-
36249021393
-
Adrenal adrenoceptors in heart failure: fine-tuning cardiac stimulation
-
Lymperopoulos, A., Rengo, G., and Koch, W. J. (2007). Adrenal adrenoceptors in heart failure: fine-tuning cardiac stimulation. Trends Mol. Med. 13, 503-511.
-
(2007)
Trends Mol. Med.
, vol.13
, pp. 503-511
-
-
Lymperopoulos, A.1
Rengo, G.2
Koch, W.J.3
-
37
-
-
84856504934
-
GRK2 inhibition in heart failure: something old, something new
-
doi: 10.2174/138161212799040510
-
Lymperopoulos, A., Rengo, G., and Koch, W. J. (2012). GRK2 inhibition in heart failure: something old, something new. Curr. Pharm. Des. 18, 186-191. doi: 10.2174/138161212799040510
-
(2012)
Curr. Pharm. Des.
, vol.18
, pp. 186-191
-
-
Lymperopoulos, A.1
Rengo, G.2
Koch, W.J.3
-
38
-
-
33847728682
-
Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure
-
doi: 10.1038/nm1553
-
Lymperopoulos, A., Rengo, G., Funakoshi, H., Eckhart, A. D., and Koch, W. J. (2007). Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure. Nat. Med. 13, 315-323. doi: 10.1038/nm1553
-
(2007)
Nat. Med.
, vol.13
, pp. 315-323
-
-
Lymperopoulos, A.1
Rengo, G.2
Funakoshi, H.3
Eckhart, A.D.4
Koch, W.J.5
-
39
-
-
77952368252
-
Reduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarction
-
doi: 10.1074/jbc. M109.077859
-
Lymperopoulos, A., Rengo, G., Gao, E., Ebert, S. N., Dorn, I. I. G. W., and Koch, W. J. (2010). Reduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarction. J. Biol. Chem. 285, 16378-16386. doi: 10.1074/jbc. M109.077859
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 16378-16386
-
-
Lymperopoulos, A.1
Rengo, G.2
Gao, E.3
Ebert, S.N.4
Dorn, I.I.G.W.5
Koch, W.J.6
-
40
-
-
38649085669
-
Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G protein-coupled receptor kinase-2 activity
-
doi: 10.1038/sj.mt.6300371
-
Lymperopoulos, A., Rengo, G., Zincarelli, C., Soltys, S., and Koch, W. J. (2008). Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G protein-coupled receptor kinase-2 activity. Mol. Ther. 16, 302-307. doi: 10.1038/sj.mt.6300371
-
(2008)
Mol. Ther.
, vol.16
, pp. 302-307
-
-
Lymperopoulos, A.1
Rengo, G.2
Zincarelli, C.3
Soltys, S.4
Koch, W.J.5
-
41
-
-
0020624726
-
Cardiovascular reflexes mediated by sympathetic afferent fibers
-
doi: 10.1016/0165-1838(83)90082-6
-
Malliani, A., Pagani, M., Pizzinelli, P., Furlan, R., and Guzzetti, S. (1983). Cardiovascular reflexes mediated by sympathetic afferent fibers. J. Auton. Nerv. Syst. 7, 295-301. doi: 10.1016/0165-1838(83)90082-6
-
(1983)
J. Auton. Nerv. Syst.
, vol.7
, pp. 295-301
-
-
Malliani, A.1
Pagani, M.2
Pizzinelli, P.3
Furlan, R.4
Guzzetti, S.5
-
42
-
-
20344401818
-
Mechanisms and models in heart failure: the biomechanical model and beyond
-
doi: 10.1161/CIRCULATIONAHA.104.500546
-
Mann, D. L., and Bristow, M. R. (2005). Mechanisms and models in heart failure: the biomechanical model and beyond. Circulation 111, 2837-2849. doi: 10.1161/CIRCULATIONAHA.104.500546
-
(2005)
Circulation
, vol.111
, pp. 2837-2849
-
-
Mann, D.L.1
Bristow, M.R.2
-
43
-
-
0031051746
-
Region-specific neuropeptide Y overflows at rest and during sympathetic activation in humans
-
doi: 10.1161/01.HYP.29.1.137
-
Morris, M. J., Cox, H. S., Lambert, G. W., Kaye, D. M., Jennings, G. L., Meredith, I. T., et al. (1997). Region-specific neuropeptide Y overflows at rest and during sympathetic activation in humans. Hypertension 29, 137-143. doi: 10.1161/01.HYP.29.1.137
-
(1997)
Hypertension
, vol.29
, pp. 137-143
-
-
Morris, M.J.1
Cox, H.S.2
Lambert, G.W.3
Kaye, D.M.4
Jennings, G.L.5
Meredith, I.T.6
-
44
-
-
33845633801
-
Alpha2-adrenoceptor subtypes involved in the regulation of catecholamine release from the adrenal medulla of mice
-
doi: 10.1038/sj.bjp.0706950
-
Moura, E., Afonso, J., Hein, L., and Vieira-Coelho, M. A. (2006). Alpha2-adrenoceptor subtypes involved in the regulation of catecholamine release from the adrenal medulla of mice. Br. J. Pharmacol. 149, 1049-1058. doi: 10.1038/sj.bjp.0706950
-
(2006)
Br. J. Pharmacol.
, vol.149
, pp. 1049-1058
-
-
Moura, E.1
Afonso, J.2
Hein, L.3
Vieira-Coelho, M.A.4
-
45
-
-
39749168495
-
Tackling heart failure in the twenty-first century
-
doi: 10.1038/nature06798
-
Mudd, J. O., and Kass, D. A. (2008). Tackling heart failure in the twenty-first century. Nature 451, 919-928. doi: 10.1038/nature06798
-
(2008)
Nature
, vol.451
, pp. 919-928
-
-
Mudd, J.O.1
Kass, D.A.2
-
46
-
-
77950286813
-
Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation
-
doi: 10.1126/science.1185988
-
Nikolaev, V. O., Moshkov, A., Lyon, A. R., Miragoli, M., Novak, P., Paur, H., et al. (2010). Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science 327, 1653-1657. doi: 10.1126/science.1185988
-
(2010)
Science
, vol.327
, pp. 1653-1657
-
-
Nikolaev, V.O.1
Moshkov, A.2
Lyon, A.R.3
Miragoli, M.4
Novak, P.5
Paur, H.6
-
47
-
-
0034535304
-
Regulation of G protein-coupled receptor kinases
-
doi: 10.1016/S1050-1738(00)00053-0
-
Penn, R. B., Pronin, A. N., and Benovic, J. L. (2000). Regulation of G protein-coupled receptor kinases. Trends Cardiovasc. Med. 10, 81-89. doi: 10.1016/S1050-1738(00)00053-0
-
(2000)
Trends Cardiovasc. Med.
, vol.10
, pp. 81-89
-
-
Penn, R.B.1
Pronin, A.N.2
Benovic, J.L.3
-
48
-
-
0033535129
-
Sympathetic activation in heart failure and its treatment with beta-blockade
-
doi: 10.1001/archinte.159.3.225
-
Pepper, G. S., and Lee, R. W. (1999). Sympathetic activation in heart failure and its treatment with beta-blockade. Arch. Intern. Med. 159, 225-234. doi: 10.1001/archinte.159.3.225
-
(1999)
Arch. Intern. Med.
, vol.159
, pp. 225-234
-
-
Pepper, G.S.1
Lee, R.W.2
-
49
-
-
0346687568
-
Adrenergic receptor knockout mice: distinct functions of 9 receptor subtypes
-
doi: 10.1016/j.pharmthera.2003.10.004
-
Philipp, M., and Hein, L. (2004). Adrenergic receptor knockout mice: distinct functions of 9 receptor subtypes. Pharmacol. Ther. 101, 65-74. doi: 10.1016/j.pharmthera.2003.10.004
-
(2004)
Pharmacol. Ther.
, vol.101
, pp. 65-74
-
-
Philipp, M.1
Hein, L.2
-
50
-
-
0036337129
-
Physiological significance of alpha(2)-adrenergic receptor subtype diversity: one receptor is not enough
-
Philipp, M., Bred, M., and Hein, L. (2002). Physiological significance of alpha(2)-adrenergic receptor subtype diversity: one receptor is not enough. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283, R287-R295.
-
(2002)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.283
-
-
Philipp, M.1
Bred, M.2
Hein, L.3
-
51
-
-
0022112835
-
Ventricular myocardial catecholamines in primates
-
Pierpont, G. L., DeMaster, E. G., Reynolds, S., Pederson, J., and Cohn, J. N. (1985). Ventricular myocardial catecholamines in primates. J. Lab. Clin. Med. 106, 205-210.
-
(1985)
J. Lab. Clin. Med.
, vol.106
, pp. 205-210
-
-
Pierpont, G.L.1
DeMaster, E.G.2
Reynolds, S.3
Pederson, J.4
Cohn, J.N.5
-
52
-
-
0026070194
-
Myocardial catecholamine concentrations in dilated cardiomyopathy and heart failure of different origins
-
Regitz, V., Leuchs, B., Bossaller, C., Sehested, J., Rappolder, M., and Fleck, E. (1991). Myocardial catecholamine concentrations in dilated cardiomyopathy and heart failure of different origins. Eur. Heart J. 12(Suppl. D), 171-174.
-
(1991)
Eur. Heart J.
, vol.12
, Issue.SUPPL. D
, pp. 171-174
-
-
Regitz, V.1
Leuchs, B.2
Bossaller, C.3
Sehested, J.4
Rappolder, M.5
Fleck, E.6
-
53
-
-
33646162635
-
GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling
-
doi: 10.1016/j.tem.2006.03.008
-
Reiter, E., and Lefkowitz, R. J. (2006). GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling. Trends Endocrinol. Metab. 17, 159-165. doi: 10.1016/j.tem.2006.03.008
-
(2006)
Trends Endocrinol. Metab.
, vol.17
, pp. 159-165
-
-
Reiter, E.1
Lefkowitz, R.J.2
-
54
-
-
77952635752
-
Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure
-
doi: 10.1152/ajpheart.00702.2009
-
Rengo, G., Leosco, D., Zincarelli, C., Marchese, M., Corbi, G., Liccardo, D., et al. (2010). Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure. Am. J. Physiol. Heart Circ. Physiol. 298, H2032-H2038. doi: 10.1152/ajpheart.00702.2009
-
(2010)
Am. J. Physiol. Heart Circ. Physiol.
, vol.298
-
-
Rengo, G.1
Leosco, D.2
Zincarelli, C.3
Marchese, M.4
Corbi, G.5
Liccardo, D.6
-
55
-
-
79953685595
-
GRK2 as a novel gene therapy target in heart failure
-
doi: 10.1016/j.yjmcc.2010.08.014
-
Rengo, G., Lymperopoulos, A., Leosco, D., and Koch, W. J. (2011). GRK2 as a novel gene therapy target in heart failure. J. Mol. Cell. Cardiol. 50, 785-792. doi: 10.1016/j.yjmcc.2010.08.014
-
(2011)
J. Mol. Cell. Cardiol.
, vol.50
, pp. 785-792
-
-
Rengo, G.1
Lymperopoulos, A.2
Leosco, D.3
Koch, W.J.4
-
56
-
-
84864444752
-
Blockade of β-adrenoceptors restores the GRK2-mediated adrenal α(2) -adrenoceptor-catecholamine production axis in heart failure
-
doi: 10.1111/j.1476-5381.2012.01972.x
-
Rengo, G., Lymperopoulos, A., Zincarelli, C., Femminella, G., Liccardo, D., Pagano, G., et al. (2012a). Blockade of β-adrenoceptors restores the GRK2-mediated adrenal α(2) -adrenoceptor-catecholamine production axis in heart failure. Br. J. Pharmacol. 166, 2430-2440. doi: 10.1111/j.1476-5381.2012.01972.x
-
(2012)
Br. J. Pharmacol.
, vol.166
, pp. 2430-2440
-
-
Rengo, G.1
Lymperopoulos, A.2
Zincarelli, C.3
Femminella, G.4
Liccardo, D.5
Pagano, G.6
-
57
-
-
84864304935
-
Targeting the β-adrenergic receptor system through gprotein- coupled receptor kinase 2: a new paradigm for therapy and prognostic evaluation in heart failure: from bench to bedside
-
doi: 10.1161/CIRCHEARTFAILURE.112.966895
-
Rengo, G., Perrone-Filardi, P., Femminella, G. D., Liccardo, D., Zincarelli, C., de Lucia, C., et al. (2012b). Targeting the β-adrenergic receptor system through gprotein- coupled receptor kinase 2: a new paradigm for therapy and prognostic evaluation in heart failure: from bench to bedside. Circ. Heart Fail. 5, 385-391. doi: 10.1161/CIRCHEARTFAILURE.112.966895
-
(2012)
Circ. Heart Fail.
, vol.5
, pp. 385-391
-
-
Rengo, G.1
Perrone-Filardi, P.2
Femminella, G.D.3
Liccardo, D.4
Zincarelli, C.5
de Lucia, C.6
-
58
-
-
0037050009
-
Seven-transmembrane-spanning receptors and heart function
-
doi: 10.1038/415206a
-
Rockman, H. A., Koch, W. J., and Lefkowitz, R. J. (2002). Seven-transmembrane-spanning receptors and heart function. Nature 415, 206-212. doi: 10.1038/415206a
-
(2002)
Nature
, vol.415
, pp. 206-212
-
-
Rockman, H.A.1
Koch, W.J.2
Lefkowitz, R.J.3
-
59
-
-
64749105265
-
Nebivolol, a vasodilating selective beta(1)-blocker, is a beta(3)-adrenoceptor agonist in the nonfailing transplanted human heart
-
doi: 10.1016/j.jacc.2008.11.057
-
Rozec, B., Erfanian, M., Laurent, K., Trochu, J. N., and Gauthier, C. (2009). Nebivolol, a vasodilating selective beta(1)-blocker, is a beta(3)-adrenoceptor agonist in the nonfailing transplanted human heart. J. Am. Coll. Cardiol. 53, 1532-1538. doi: 10.1016/j.jacc.2008.11.057
-
(2009)
J. Am. Coll. Cardiol.
, vol.53
, pp. 1532-1538
-
-
Rozec, B.1
Erfanian, M.2
Laurent, K.3
Trochu, J.N.4
Gauthier, C.5
-
60
-
-
33750363223
-
Effect of alpha1-adrenergic receptors in cardiac pathophysiology
-
doi: 10.1016/j.ahj.2006.05.017
-
Shannon, R., and Chaudhry, M. (2006). Effect of alpha1-adrenergic receptors in cardiac pathophysiology. Am. Heart J. 152, 842-850. doi: 10.1016/j.ahj.2006.05.017
-
(2006)
Am. Heart J.
, vol.152
, pp. 842-850
-
-
Shannon, R.1
Chaudhry, M.2
-
61
-
-
51349085441
-
Beta3-adrenergic receptor activation increases human atrial tissue contractility and stimulates the L-type Ca2+ current
-
Skeberdis, V. A., Gendviliene, V., Zablockaite, D., Treinys, R., Macianskiene, R., Bogdelis, A., et al. (2008). Beta3-adrenergic receptor activation increases human atrial tissue contractility and stimulates the L-type Ca2+ current. J. Clin. Invest. 118, 3219-3227.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3219-3227
-
-
Skeberdis, V.A.1
Gendviliene, V.2
Zablockaite, D.3
Treinys, R.4
Macianskiene, R.5
Bogdelis, A.6
-
62
-
-
70350513886
-
The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications
-
doi: 10.1016/j.jacc.2009.05.015
-
Triposkiadis, F., Karayannis, G., Giamouzis, G., Skoularigis, J., Louridas, G., and Butler, J. (2009). The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications. J. Am. Coll. Cardiol. 54, 1747-1762. doi: 10.1016/j.jacc.2009.05.015
-
(2009)
J. Am. Coll. Cardiol.
, vol.54
, pp. 1747-1762
-
-
Triposkiadis, F.1
Karayannis, G.2
Giamouzis, G.3
Skoularigis, J.4
Louridas, G.5
Butler, J.6
-
63
-
-
1842455238
-
Prevention of sympathetic and cardiac dysfunction after myocardial infarction in transgenic rats deficient in brain angiotensinogen
-
doi: 10.1161/01.RES.0000120864.21172.5A
-
Wang, H., Huang, B. S., Ganten, D., and Leenen, F. H. H. (2004). Prevention of sympathetic and cardiac dysfunction after myocardial infarction in transgenic rats deficient in brain angiotensinogen. Circ. Res. 94, 843-849. doi: 10.1161/01.RES.0000120864.21172.5A
-
(2004)
Circ. Res.
, vol.94
, pp. 843-849
-
-
Wang, H.1
Huang, B.S.2
Ganten, D.3
Leenen, F.H.H.4
-
64
-
-
38849129420
-
Cardiac alpha 1-adrenergic drive in pathological remodelling
-
doi: 10.1093/cvr/cvm078
-
Woodcock, E. A., Du, X. J., Reichelt, M. E., and Graham, R. M. (2008). Cardiac alpha 1-adrenergic drive in pathological remodelling. Cardiovasc. Res. 77, 452-462. doi: 10.1093/cvr/cvm078
-
(2008)
Cardiovasc. Res.
, vol.77
, pp. 452-462
-
-
Woodcock, E.A.1
Du, X.J.2
Reichelt, M.E.3
Graham, R.M.4
-
65
-
-
0035852634
-
Dual modulation of cell survival and cell death by β2-adrenergic signalling in adult mouse cardiomyocytes
-
doi: 10.1073/pnas.98.4.1607
-
Zhu, W. Z., Zheng, M., Koch, W. J., Lefkowitz, R. J., Kobilka, B. K., and Xiao, R. P. (2001). Dual modulation of cell survival and cell death by β2-adrenergic signalling in adult mouse cardiomyocytes. Proc. Natl. Acad. Sci. U.S.A. 98, 1607-1612. doi: 10.1073/pnas.98.4.1607
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 1607-1612
-
-
Zhu, W.Z.1
Zheng, M.2
Koch, W.J.3
Lefkowitz, R.J.4
Kobilka, B.K.5
Xiao, R.P.6
-
66
-
-
47249111218
-
Heart-brain interactions in cardiac arrhythmias: role of the autonomic nervous system
-
doi: 10.3949/ccjm.75.Suppl_2.S94
-
Zipes, D. P. (2008). Heart-brain interactions in cardiac arrhythmias: role of the autonomic nervous system. Cleve. Clin. J. Med. 75, S94-S96. doi: 10.3949/ccjm.75.Suppl_2.S94
-
(2008)
Cleve. Clin. J. Med.
, vol.75
-
-
Zipes, D.P.1
|