-
1
-
-
79961027577
-
Applications and trends in systems biology in biochemistry
-
Hübner K, Sahle S, Kummer U. Applications and trends in systems biology in biochemistry. FEBS J. 278(16), 2767-2857 (2012
-
(2012)
FEBS J.
, vol.278
, Issue.16
, pp. 2767-2857
-
-
Hübner, K.1
Sahle, S.2
Kummer, U.3
-
2
-
-
79951494456
-
Computational models for analyzing lipoprotein profiles
-
de Graaf AA, van Schalkwijk DB. Computational models for analyzing lipoprotein profiles. Clin. Lipidol. 6(1), 25-33 (2011
-
(2011)
Clin. Lipidol.
, vol.6
, Issue.1
, pp. 25-33
-
-
De Graaf, A.A.1
Van Schalkwijk, D.B.2
-
3
-
-
33747100291
-
Thematic review series: Patient-oriented research What we have learned about VLDL and LDL metabolism from human kinetics studies
-
Parhofer KG, Barrett PH. Thematic review series: Patient-oriented research. What we have learned about VLDL and LDL metabolism from human kinetics studies. J. Lipid Res. 47(8), 1620-1630 (2006
-
(2006)
J. Lipid Res.
, vol.47
, Issue.8
, pp. 1620-1630
-
-
Parhofer, K.G.1
Barrett, P.H.2
-
4
-
-
33747145594
-
Thematic review series: Patient-oriented research Design and analysis of lipoprotein tracer kinetics studies in humans
-
Barrett PH, Chan DC, Watts GF. Thematic review series: Patient-oriented research. Design and analysis of lipoprotein tracer kinetics studies in humans. J. Lipid Res. 47(8), 1607-1619 (2006
-
(2006)
J. Lipid Res.
, vol.47
, Issue.8
, pp. 1607-1619
-
-
Barrett, P.H.1
Chan, D.C.2
Watts, G.F.3
-
5
-
-
33747119727
-
Thematic review series: Patient-oriented research What have we learned about HDL metabolism from kinetics studies in humans?
-
Rashid S, Patterson BW, Lewis GF. Thematic review series: Patient-oriented research. What have we learned about HDL metabolism from kinetics studies in humans?. J. Lipid Res. 47(8), 1631-1642 (2006
-
(2006)
J. Lipid Res.
, vol.47
, Issue.8
, pp. 1631-1642
-
-
Rashid, S.1
Patterson, B.W.2
Lewis, G.F.3
-
6
-
-
84870547907
-
Targeting high density lipoproteins in the prevention of cardiovascular disease?
-
Larach DB, deGoma EM, Rader DJ. Targeting high density lipoproteins in the prevention of cardiovascular disease?. Curr. Cardiol. Rep. 14, 684-691 (2012
-
(2012)
Curr. Cardiol. Rep.
, vol.14
, pp. 684-691
-
-
Larach, D.B.1
De Goma, E.M.2
Rader, D.J.3
-
7
-
-
84870045994
-
Effects of dalcetrapib in patients with a recent acute coronary syndrome
-
Schwartz GG, Olsson AG, Ballantyne CM et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N. Engl. J. Med. 367(22), 2089-2099 (2012
-
(2012)
N. Engl. J. Med.
, vol.367
, Issue.22
, pp. 2089-2099
-
-
Schwartz, G.G.1
Olsson, A.G.2
Ballantyne, C.M.3
-
8
-
-
0343505456
-
Structure of human serum lipoproteins inferred from compositional analysis
-
Shen BW, Scanu AM, Kézdy FJ. Structure of human serum lipoproteins inferred from compositional analysis. Proc. Natl Acad. Sci. USA 74(3), 837-841 (1977
-
(1977)
Proc. Natl Acad. Sci. USA
, vol.74
, Issue.3
, pp. 837-841
-
-
Shen, B.W.1
Scanu, A.M.2
Kézdy, F.J.3
-
9
-
-
80054950510
-
Molecular dynamics simulations and drug discovery
-
Durrant JD, McCammon JA. Molecular dynamics simulations and drug discovery. BMC Biol. 9, 71 (2011
-
(2011)
BMC Biol.
, vol.9
, Issue.71
-
-
Durrant, J.D.1
McCammon, J.A.2
-
10
-
-
78349243645
-
Role of lipids in spheroidal high density lipoproteins
-
Vuorela T, Catte A, Niemelä PS et al. Role of lipids in spheroidal high density lipoproteins. PLoS Comput. Biol. 6(10), e1000964 (2010
-
(2010)
PLoS Comput. Biol.
, vol.6
, Issue.10
-
-
Vuorela, T.1
Catte, A.2
Niemelä, P.S.3
-
11
-
-
79953330326
-
The low resolution structure of apoA1 in spherical high density lipoprotein revealed by small angle neutron scattering
-
Wu Z, Gogonea V, Lee X et al. The low resolution structure of apoA1 in spherical high density lipoprotein revealed by small angle neutron scattering. J. Biol. Chem. 286(14), 12495-12508 (2011
-
(2011)
J. Biol. Chem.
, vol.286
, Issue.14
, pp. 12495-12508
-
-
Wu, Z.1
Gogonea, V.2
Lee, X.3
-
12
-
-
50449097333
-
Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes
-
Silva RA, Huang R, Morris J et al. Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes. Proc. Natl Acad. Sci. USA 105(34), 12176-12181 (2008
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.34
, pp. 12176-12181
-
-
Silva, R.A.1
Huang, R.2
Morris, J.3
-
13
-
-
79953800922
-
Apolipoprotein A-I structural organization in high-density lipoproteins isolated from human plasma
-
Huang R, Silva RA, Jerome WG et al. Apolipoprotein A-I structural organization in high-density lipoproteins isolated from human plasma. Nat. Struct. Mol. Biol. 18(4), 416-422 (2011
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, Issue.4
, pp. 416-422
-
-
Huang, R.1
Silva, R.A.2
Jerome, W.G.3
-
14
-
-
80051969523
-
High density lipoprotein structural changes and drug response in lipidomic profiles following the long-term fenofibrate therapy in the FIELD substudy
-
Yetukuri L, Huopaniemi I, Koivuniemi A et al. High density lipoprotein structural changes and drug response in lipidomic profiles following the long-term fenofibrate therapy in the FIELD substudy. PLoS ONE 6(8), e23589 (2011
-
(2011)
PLoS ONE
, vol.6
, Issue.8
-
-
Yetukuri, L.1
Huopaniemi, I.2
Koivuniemi, A.3
-
15
-
-
84878457545
-
A comparison of the theoretical relationship between HDL size and the ratio of HDL cholesterol to apolipoprotein A-I with experimental results from the women's health study
-
Mazer NA, Giulianini F, Paynter NP, Jordan P, Mora S. A comparison of the theoretical relationship between HDL size and the ratio of HDL cholesterol to apolipoprotein A-I with experimental results from the women's health study. Clin. Chem. 59(6), 949-958 (2013
-
(2013)
Clin. Chem.
, vol.59
, Issue.6
, pp. 949-958
-
-
Mazer, N.A.1
Giulianini, F.2
Paynter, N.P.3
Jordan, P.4
Mora, S.5
-
16
-
-
77953545927
-
Lipidomics as a tool for the study of lipoprotein metabolism
-
Kontush A, Chapman MJ. Lipidomics as a tool for the study of lipoprotein metabolism. Curr. Atheroscler. Rep. 12(3), 194-201 (2010
-
(2010)
Curr. Atheroscler. Rep.
, vol.12
, Issue.3
, pp. 194-201
-
-
Kontush, A.1
Chapman, M.J.2
-
17
-
-
85027940419
-
Lipidomics is providing new insight into the metabolic syndrome and its sequelae
-
Meikle PJ, Christopher MJ. Lipidomics is providing new insight into the metabolic syndrome and its sequelae. Curr. Opin. Lipidol. 22(3), 210-215 (2011
-
(2011)
Curr. Opin. Lipidol.
, vol.22
, Issue.3
, pp. 210-215
-
-
Meikle, P.J.1
Christopher, M.J.2
-
18
-
-
77956809106
-
Dynamic simulation of cardiolipin remodeling: Greasing the wheels for an interpretative approach to lipidomics
-
Kiebish MA, Bell R, Yang K et al. Dynamic simulation of cardiolipin remodeling: Greasing the wheels for an interpretative approach to lipidomics. J. Lipid Res. 51(8), 2153-2170 (2010
-
(2010)
J. Lipid Res.
, vol.51
, Issue.8
, pp. 2153-2170
-
-
Kiebish, M.A.1
Bell, R.2
Yang, K.3
-
19
-
-
34547840225
-
Exploring the lipoprotein composition using Bayesian regression on serum lipidomic profiles
-
Sysi-Aho M, Vehtari A, Velagapudi VR et al. Exploring the lipoprotein composition using Bayesian regression on serum lipidomic profiles. Bioinformatics 23(13), 519-528 (2007
-
(2007)
Bioinformatics
, vol.23
, Issue.13
, pp. 519-528
-
-
Sysi-Aho, M.1
Vehtari, A.2
Velagapudi, V.R.3
-
20
-
-
84855375853
-
The emerging role of plasma lipidomics in cardiovascular drug discovery
-
Puri R, Duong M, Uno K, Kataoka Y, Nicholls SJ. The emerging role of plasma lipidomics in cardiovascular drug discovery. Expert Opin. Drug Discov. 7(1), 63-72 (2012
-
(2012)
Expert Opin. Drug Discov.
, vol.7
, Issue.1
, pp. 63-72
-
-
Puri, R.1
Duong, M.2
Uno, K.3
Kataoka, Y.4
Nicholls, S.J.5
-
21
-
-
53349173867
-
Lipidomic approach to evaluate rosuvastatin and atorvastatin at various dosages: Investigating differential effects among statins
-
Bergheanu SC, Reijmers T, Zwinderman AH et al. Lipidomic approach to evaluate rosuvastatin and atorvastatin at various dosages: Investigating differential effects among statins. Curr. Med. Res. Opin. 24(9), 2477-2487 (2008
-
(2008)
Curr. Med. Res. Opin.
, vol.24
, Issue.9
, pp. 2477-2487
-
-
Bergheanu, S.C.1
Reijmers, T.2
Zwinderman, A.H.3
-
22
-
-
84862178375
-
Clustering by plasma lipoprotein profile reveals two distinct subgroups with positive lipid response to fenofibrate therapy
-
van Bochove K, van Schalkwijk DB, Parnell LD et al. Clustering by plasma lipoprotein profile reveals two distinct subgroups with positive lipid response to fenofibrate therapy. PLoS ONE 7(6), e38072 (2012
-
(2012)
PLoS ONE
, vol.7
, Issue.6
-
-
Van Bochove, K.1
Van Schalkwijk, D.B.2
Parnell, L.D.3
-
23
-
-
2142807300
-
New model for kinetic studies of HDL metabolism in humans
-
Chétiveaux M, Ouguerram K, Zair Y et al. New model for kinetic studies of HDL metabolism in humans. Eur. J. Clin. Invest. 34(4), 262-267 (2004
-
(2004)
Eur. J. Clin. Invest.
, vol.34
, Issue.4
, pp. 262-267
-
-
Chétiveaux, M.1
Ouguerram, K.2
Zair, Y.3
-
24
-
-
77952422358
-
The effect of PPAR-A agonism on apolipoprotein metabolism in humans
-
Shah A, Rader DJ, Millar JS. The effect of PPAR-a agonism on apolipoprotein metabolism in humans. Atherosclerosis 1, 35-40 (2010
-
(2010)
Atherosclerosis
, vol.1
, pp. 35-40
-
-
Shah, A.1
Rader, D.J.2
Millar, J.S.3
-
25
-
-
0019962313
-
Multicompartmental analysis of cholesterol metabolism in man Quantitative kinetic evaluation of precursor sources and turnover of high density lipoprotein cholesterol esters
-
Schwartz CC, Berman M, Vlahcevic ZR, Swell L. Multicompartmental analysis of cholesterol metabolism in man. Quantitative kinetic evaluation of precursor sources and turnover of high density lipoprotein cholesterol esters. J. Clin. Invest. 70(4), 863-876 (1982
-
(1982)
J. Clin. Invest.
, vol.70
, Issue.4
, pp. 863-876
-
-
Schwartz, C.C.1
Berman, M.2
Vlahcevic, Z.R.3
Swell, L.4
-
26
-
-
4544331579
-
Lipoprotein cholesteryl ester production, transfer, and output in vivo in humans
-
Schwartz CC, VandenBroek JM, Cooper PS. Lipoprotein cholesteryl ester production, transfer, and output in vivo in humans. J. Lipid Res. 45(9), 1594-1607 (2004
-
(2004)
J. Lipid Res.
, vol.45
, Issue.9
, pp. 1594-1607
-
-
Schwartz, C.C.1
VandenBroek, J.M.2
Cooper, P.S.3
-
27
-
-
0036148305
-
A new labeling approach using stable isotopes to study in vivo plasma cholesterol metabolism in humans
-
Ouguerram K, Krempf M, Maugeais C, Maugère P, Darmaun D, Magot T. A new labeling approach using stable isotopes to study in vivo plasma cholesterol metabolism in humans. Metabolism 51(1), 5-11 (2002
-
(2002)
Metabolism
, vol.51
, Issue.1
, pp. 5-11
-
-
Ouguerram, K.1
Krempf, M.2
Maugeais, C.3
Maugère, P.4
Darmaun, D.5
Magot, T.6
-
28
-
-
84869991362
-
Measurement of reverse cholesterol transport pathways in humans: In vivo rates of free cholesterol efflux, esterification, and excretion
-
Turner S, Voogt J, Davidson M et al. Measurement of reverse cholesterol transport pathways in humans: In vivo rates of free cholesterol efflux, esterification, and excretion. J. Am. Heart Assoc. 4, e001826 (2012
-
(2012)
J. Am. Heart Assoc.
, vol.4
-
-
Turner, S.1
Voogt, J.2
Davidson, M.3
-
29
-
-
9444266171
-
CellDesigner: A process diagram editor for gene-regulatory and biochemical networks
-
Funahashi A, Tanimura N, Morohashi M, Kitano H. CellDesigner: A process diagram editor for gene-regulatory and biochemical networks. BIOSILICO 1, 159-162 (2003
-
(2003)
Biosilico
, vol.1
, pp. 159-162
-
-
Funahashi, A.1
Tanimura, N.2
Morohashi, M.3
Kitano, H.4
-
30
-
-
65649138437
-
Computational modeling of biochemical networks using COPASI
-
Mendes P, Hoops S, Sahle S, Gauges R, Dada J, Kummer U. Computational modeling of biochemical networks using COPASI. Methods Mol. Biol. 500, 17-59 (2009
-
(2009)
Methods Mol. Biol.
, vol.500
, pp. 17-59
-
-
Mendes, P.1
Hoops, S.2
Sahle, S.3
Gauges, R.4
Dada, J.5
Kummer, U.6
-
31
-
-
0031940813
-
SAAM II: Simulation, analysis, and modeling software for tracer and pharmacokinetic studies
-
Barrett PH, Bell BM, Cobelli C et al. SAAM II: Simulation, analysis, and modeling software for tracer and pharmacokinetic studies. Metabolism 47, 484-492 (1998
-
(1998)
Metabolism
, vol.47
, pp. 484-492
-
-
Barrett, P.H.1
Bell, B.M.2
Cobelli, C.3
-
32
-
-
70350366589
-
Mechanism of inhibition defines CETP activity: A mathematical model for CETP in vitro
-
Potter LK, Sprecher DL, Walker MC, Tobin FL. Mechanism of inhibition defines CETP activity: A mathematical model for CETP in vitro. J. Lipid Res. 50(11), 2222-2234 (2009
-
(2009)
J. Lipid Res.
, vol.50
, Issue.11
, pp. 2222-2234
-
-
Potter, L.K.1
Sprecher, D.L.2
Walker, M.C.3
Tobin, F.L.4
-
33
-
-
0033673149
-
A pathway model of lipid metabolism to predict the effect of genetic variability on lipid levels
-
Knoblauch H, Schuster H, Luft FC, Reich JG. A pathway model of lipid metabolism to predict the effect of genetic variability on lipid levels. J. Mol. Med. 78, 507-515 (2000
-
(2000)
J. Mol. Med.
, vol.78
, pp. 507-515
-
-
Knoblauch, H.1
Schuster, H.2
Luft, F.C.3
Reich, J.G.4
-
34
-
-
44949245858
-
Computational lipidology: Predicting lipoprotein density profiles in human blood plasma
-
Hübner K, Schwager T, Winkler K, Reich JG, Holzhütter HG. Computational lipidology: Predicting lipoprotein density profiles in human blood plasma. PLoS Comput. Biol. 4, e1000079 (2008
-
(2008)
PLoS Comput. Biol.
, vol.4
-
-
Hübner, K.1
Schwager, T.2
Winkler, K.3
Reich, J.G.4
Holzhütter, H.G.5
-
35
-
-
84862189675
-
Diagnostic markers based on a computational model of lipoprotein metabolism
-
van Schalkwijk DB, van Ommen B, Freidig AP, van der Greef J, de Graaf AA. Diagnostic markers based on a computational model of lipoprotein metabolism. J. Clin. Bioinforma. 1(1), 29 (2011
-
(2011)
J. Clin. Bioinforma.
, vol.1
, Issue.1
, pp. 29
-
-
Van Schalkwijk, D.B.1
Van Ommen, B.2
Freidig, A.P.3
Van Der Greef, J.4
De Graaf, A.A.5
-
36
-
-
84867213571
-
A whole-body mathematical model of cholesterol metabolism and its age-associated dysregulation
-
McAuley MT, Wilkinson DJ, Jones JJ, Kirkwood TB. A whole-body mathematical model of cholesterol metabolism and its age-associated dysregulation. BMC Syst. Biol. 6, 130 (2012
-
(2012)
BMC Syst. Biol.
, vol.6
, Issue.130
-
-
McAuley, M.T.1
Wilkinson, D.J.2
Jones, J.J.3
Kirkwood, T.B.4
-
37
-
-
84869021740
-
A physiologically based in silico kinetic model predicting plasma cholesterol concentrations in humans
-
van de Pas NC, Woutersen RA, van Ommen B, Rietjens IM, de Graaf AA. A physiologically based in silico kinetic model predicting plasma cholesterol concentrations in humans. J. Lipid Res. 53(12), 2734-2746 (2012
-
(2012)
J. Lipid Res.
, vol.53
, Issue.12
, pp. 2734-2746
-
-
Van De Pas, N.C.1
Woutersen, R.A.2
Van Ommen, B.3
Rietjens, I.M.4
De Graaf, A.A.5
-
38
-
-
84885833167
-
ABCA1 up-regulation but not CETP inhibition is predicted to increase the reverse cholesterol transport (RCT) input rate: A simulation study of HDL-C raising targets using a novel in-silico model of lipoprotein metabolism and kinetics
-
Lu J, Nanjee MN, Brinton EA, Hübner K, Mazer NA. ABCA1 up-regulation but not CETP inhibition is predicted to increase the reverse cholesterol transport (RCT) input rate: A simulation study of HDL-C raising targets using a novel in-silico model of lipoprotein metabolism and kinetics. Arterioscler. Thromb. Vasc. Biol. Abstract 443 (2013
-
(2013)
Arterioscler. Thromb. Vasc. Biol. Abstract
, vol.443
-
-
Lu, J.1
Nanjee, M.N.2
Brinton, E.A.3
Hübner, K.4
Mazer, N.A.5
-
39
-
-
84884583362
-
Association between reverse cholesterol transport rate and lipoprotein biomarkers using a novel in silico model of lipoprotein metabolism and kinetics
-
Abstract A-547-0010-01108
-
Lu J, Hübner K, Brinton EA, Nanjee MN, Mazer NA. Association between reverse cholesterol transport rate and lipoprotein biomarkers using a novel in silico model of lipoprotein metabolism and kinetics. Eur. Atheroscler. Soc. Congr. Abstract A-547-0010-01108 (2013
-
(2013)
Eur. Atheroscler. Soc. Congr
-
-
Lu, J.1
Hübner, K.2
Brinton, E.A.3
Nanjee, M.N.4
Mazer, N.A.5
|