Embelia ribes extract reduces high fat diet and low dose streptozotocin-induced diabetic nephrotoxicity in rats

EXCLI Journal

Volumn 12, Issue , 2013, Pages 858-871

  Chaudhari, Hemantkumar Somabhai ^a   Bhandari, Uma ^a   Khanna, Geetika ^b  

^a HAMDARD UNIVERSITY   (India)

^b SAFDARJUNG HOSPITAL   (India)

Author keywords

Creatinine; High fat diet; Insulin; Nephropathy; Streptozotocin; Type 2 diabetes

Indexed keywords

ALCOHOL; ALKALINE PHOSPHATASE; CATALASE; CHOLESTEROL; CREATININE; EMBELIA RIBES EXTRACT; GLUTATHIONE; LACTATE DEHYDROGENASE; PLANT EXTRACT; SERUM ALBUMIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALBUMIN BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; FRUIT; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HISTOPATHOLOGY; INSULIN SENSITIVITY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID METABOLISM; MALE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PROTEIN BLOOD LEVEL; RAT; STREPTOZOCIN DIABETES; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

EID: 84884573108     PISSN: None     EISSN: 16112156     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Alhaider AA, Korashy HM, Ahmed MS, Mobark M, Kfoury H, Mansour MA. Met-ormin attenuates streptozotocin-induced diabetic nephropathy in rats through modulation of oxidative stress genes expression. Chem Biol Interact 2011;192: 233-42.
2. Ansari MN, Bhandari U. High Performance Thin Layer Chromatographic method for quantification of embelin from Embelia Ribes Burm fruits. Indian Drugs 2008;45: 908-10.
3. Aragno M, Mastrocola R, Catalano MG, Brignardello E, Danni O, Boccuzzi G. Oxidative stress impairs skeletal muscle repair in diabetic rats. Diabetes 2004;53: 1082-8.
4. Balakumar P, Arora MK, Ganti SS, Reddy J, Singh M. Recent advances in pharmaco-therapy for diabetic nephropathy: Current perspectives and future directions. Pharmacol Res 2009;60:24-32.
5. Bhandari U, Kanojia R, Pillai KK. Effect of ethanolic extract of Embelia ribes on dyslipidemia in diabetic rats. Int J Exp Diab Res 2002;3:159-62.
6. Bhandari U, Jain N, Pillai KK. Further studies on antioxidant potential and protection of pancreatic β-cells by Embelia ribes in experimental diabetes. Exp Diab Res 2007;2007:1-6.
7. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001;414:813-20.
8. Calberg I, Mannerviek B. Glutathione reductase levels in rat brain. J Biol Chem 1975;250:5475-80.
9. Caliborne AL. Assay of catalase. In: Greenwald RA (ed.): Handbook of methods of oxygen radical research (pp 283-5). Boca Raton, FL: CRC Press, 1985.
10. Chaudhari HS, Bhandari U, Khanna G. Preventive effect of embelin from Embelia ribes on lipid metabolism and oxidative stress in high-fat diet-induced obesity in rats. Planta Med 2012;78:651-7.
11. Cooper ME. Interaction metabolic and hemodynamic factors in mediating experimental diabetic nephropathy. Diabetologia 2001;44:1957-72.
12. Danda RS, Habiba NM, Rincon-Choles H, Bhandari BK, Barnes JL, Abboud HE et al. Kidney involvement in a nongenetic rat model of type 2 diabetes. Kidney Int 2005; 68:2562-71.
13. Dominguez JH, Tang N, Xu W, Evan AP, Siakotos AN, Agarwal R et al. Studies of renal injury III: Lipid-induced nephropathy in type II diabetes. Kidney Int 2000;57:92-104.
14. Ha H, Kim KH. Pathogenesis of diabetic nephropathy: the role of oxidative stress and protein kinase C. Diabetes Res Clin Pract 1999;45:147-51.
15. Hall PM. Prevention of progression in diabetic nephropathy. Diabetes Spectr 2006: 18-24.
16. Hostetter TH, Rennke HG, Brenner BM. The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies. Am J Med 1982; 72:375-80.
17. Knight SF, Imig JD. Obesity, insulin resistance, and renal function. Microcircul-ation 2007;14:349-62.
18. Kramer H. Screening for kidney disease in adults with diabetes mellitus: don't forget serum creatinine. Am J Kidney Dis 2004; 44:921-3.
19. Krentz AJ. Antidiabetic treatment in obese patients with type 2 diabetes-effects of medication on bodyweight. Eur Endocrin Dis 2007:32-6.
20. Lindblom P, Rafter I, Copley C, Andersson U, Hedberg JJ, Berg AL et al. Isoforms of alanine aminotransferases in human tissues and serum differential tissue expression using novel antibodies. Arch Biochem Biophys 2007;466:66-77.
21. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193:265-75.
22. Madhavan SN, Arimboor R, Arumughan C. RP-HPLC-DAD method for the estimation of embelin as marker in Embelia ribes and its polyherbal formulations. Biomed Chro-matogr 2011;25:600-5.
23. Marklund S, Marklund G. Involvement of the superoxide anion radical in the autooxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974;47:469-74.
24. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid. Anal Biochem 1979;95: 359-64.
25. Reaven GM. Why Syndrome X? From Harold Himsworth to the insulin resistance syndrome. Cell Metab 2005;1:9-14.
26. Roy S, Trudeau K, Roy S, Behl Y, Dhar S, Chronopoulos A. New insights into hyper-glycemia-induced molecular changes in microvascular cells. J Dent Res 2010;89: 116-28.
27. Ruggenenti P, Remuzzi G. Nephropathy of type 1 and type 2 diabetes: diverse patho-physiology, same treatment? Nephrol Dial Transplant 2000;15:1900-2.
28. Sanchez Navarro MR, Fernandez-Conde ME, Martin SB, Samaniego C. Alkaline phosphatase isoenzymes in the serum of patient with renal insufficiency. An Med Int 2002;19:449-52.
29. Shafi S, Tabassum N, Ahmad F. Diabetic nephropathy and herbal medicines. Int J Phytopharmacol 2012;3:10-17.
30. Shelar R, Maurya C, Tekale P, Katkar K, Naik V, Suthar A et al. Embelin: An HPLC method for quantitative estimation in Embelia ribes Burm. F. Int J Pharm Clin Res 2009;1:146-9.
31. Srinivasan K, Viswanad B, Asrat L, Kaul CL, Ramarao P. Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: A model for type 2 diabetes and pharmacological screening. Pharmacol Res 2005;52:313-20.
32. Tomohiro T, Kumai T, Sato T, Takeba Y, Kobayashi S, Kimura K. Hypertension aggravates glomerular dysfunction with oxidative stress in a rat model of diabetic nephropathy. Life Sciences 2007;80:1364-72.
33. Veerapur VP, Prabhakar KR, Kandadi MR, Srinivasan KK, Unnikrishnan MK. Antidia-betic effect of Dodonaea viscosa aerial parts in high fat diet and low dose streptozotocin-induced type 2 diabetic rats: A mechanistic approach. Pharm Biol 2010; 48:1137-48.
34. Yokoyama M, Tanigawa K, Murata T, Kobayashi Y, Tada E, Suzuki I et al. Dietary polyunsaturated fatty acids slow the progression of diabetic nephropathy in streptozotocin-induced diabetic rats. Nutr Res 2010;30:217-25.
35. Zhang L, Yang J, Chen X, Zan K, Wen X, Chen H et al. Antidiabetic and antioxidant effects of extracts from Potentilla discolour Bunge on diabetic rats induced by high fat diet and streptozotocin. J Ethnopharmacol 2010;132:518-24.