-
1
-
-
20244387586
-
Chemoradiation with and without surgery in patients with locally advanced squamous cell carcinoma of the esophagus
-
DOI 10.1200/JCO.2005.00.034
-
Stahl M, Stuschke M, Lehmann N, et al. Chemoradiation with and without surgery in patients with locally advanced squamous cell carcinoma of the esophagus. J Clin Oncol. 2005;23:2310-7. (Pubitemid 46218723)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.10
, pp. 2310-2317
-
-
Stahl, M.1
Stuschke, M.2
Lehmann, N.3
Meyer, H.-J.4
Walz, M.K.5
Seeber, S.6
Klump, B.7
Budach, W.8
Teichmann, R.9
Schmitt, M.10
Schmitt, G.11
Franke, C.12
Wilke, H.13
-
2
-
-
0033526355
-
Chemoradiotherapy of locally advanced esophageal cancer: Long-term follow-up of a prospective randomized trial (RTOG 85-01)
-
DOI 10.1001/jama.281.17.1623
-
Cooper JS, Guo MD, Herskovic A, et al. Chemoradiotherapy of locally advanced esophageal cancer: Long term follow-up of a prospective randomized trial (RTOG 85-01). JAMA. 1999;281:1623-7. (Pubitemid 29211772)
-
(1999)
Journal of the American Medical Association
, vol.281
, Issue.17
, pp. 1623-1627
-
-
Cooper, J.S.1
Guo, M.D.2
Herskovic, A.3
Macdonald, J.S.4
Martenson Jr., J.A.5
Al-Sarraf, M.6
Byhardt, R.7
Russell, A.H.8
Beitler, J.J.9
Spencer, S.10
Asbell, S.O.11
Graham, M.V.12
Leichman, L.L.13
-
3
-
-
34247150339
-
Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus; FFCD 9102
-
Bedenne L, Michel P, Bouche O, et al. Chemoradiation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus; FFCD 9102. J Clin Oncol. 2007;25:1160-7.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1160-1167
-
-
Bedenne, L.1
Michel, P.2
Bouche, O.3
-
4
-
-
0029737381
-
A comparison of multimodal therapy and surgery for esophageal adenocarcinoma
-
DOI 10.1056/NEJM199608153350702
-
Walsh TN, Noonan N, Hollywood D, et al. A comparison of multimodal therapy and surgery for esophageal adenocarcinoma. N Eng J Med. 1996;335:462-7. (Pubitemid 26269945)
-
(1996)
New England Journal of Medicine
, vol.335
, Issue.7
, pp. 462-467
-
-
Walsh, T.N.1
Noonan, N.2
Hollywood, D.3
Kelly, A.4
Keeling, N.5
Hennessy, T.P.J.6
-
5
-
-
0035818048
-
Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction
-
Macdonald JS, Smalley SR, Benedetti J, et al. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. N Eng J Med. 2001;345:725-30.
-
(2001)
N Eng J Med
, vol.345
, pp. 725-730
-
-
Macdonald, J.S.1
Smalley, S.R.2
Benedetti, J.3
-
6
-
-
76949094319
-
Long term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer
-
Allum WH, Stenning SP, Bancewicz J, et al. Long term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer. J Clin Oncol. 2009;27:5062-7.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5062-5067
-
-
Allum, W.H.1
Stenning, S.P.2
Bancewicz, J.3
-
7
-
-
33745726677
-
Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer
-
Cunningham D, Allum WH, Stenning SP, et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Eng J Med. 2006;335:11-20.
-
(2006)
N Eng J Med
, vol.335
, pp. 11-20
-
-
Cunningham, D.1
Allum, W.H.2
Stenning, S.P.3
-
8
-
-
79959572435
-
Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: An updated meta-analysis
-
This is a large meta-analysis which provides strong evidence for a survival benefit from preoperative chemotherapy and chemoradiotherapy as compared to surgery alone in patients with esophageal cancer. The benefits of these treatment modalities are further analyzed by tumor histology
-
• Sjoquist KM, Burmeister BH, Smithers BM, et al. Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: An updated meta-analysis. Lancet Oncol. 2011;12:681-92. This is a large meta-analysis which provides strong evidence for a survival benefit from preoperative chemotherapy and chemoradiotherapy as compared to surgery alone in patients with esophageal cancer. The benefits of these treatment modalities are further analyzed by tumor histology.
-
(2011)
Lancet Oncol.
, vol.12
, pp. 681-692
-
-
Sjoquist, K.M.1
Burmeister, B.H.2
Smithers, B.M.3
-
9
-
-
60849118127
-
Phase III comparison of preoperative chemotherapy compared with chemoradiotherapy in patients with locally advanced adenocarcinoma of the esophagogastric junction
-
This randomized phase III trial which focused exclusively on patients with adenocarcinoma of the proximal stomach, gastroesophageal junction, and distal esophagus, demonstrated significantly improved pathologic complete response rates with preoperative concurrent chemoradiation compared to preoperative chemotherapy. While there appears to be a trend favoring chemoradiotherapy, the improvements in survival outcomes were not statistically significant
-
• Stahl M, Walz MK, Stuschke M, et al. Phase III comparison of preoperative chemotherapy compared with chemoradiotherapy in patients with locally advanced adenocarcinoma of the esophagogastric junction. J Clin Oncol. 2009;27:851-6. This randomized phase III trial which focused exclusively on patients with adenocarcinoma of the proximal stomach, gastroesophageal junction, and distal esophagus, demonstrated significantly improved pathologic complete response rates with preoperative concurrent chemoradiation compared to preoperative chemotherapy. While there appears to be a trend favoring chemoradiotherapy, the improvements in survival outcomes were not statistically significant.
-
(2009)
J Clin Oncol.
, vol.27
, pp. 851-856
-
-
Stahl, M.1
Walz, M.K.2
Stuschke, M.3
-
10
-
-
79251595542
-
Is concurrent radiation therapy required in patients receiving chemotherapy for adenocarcinoma of the oesophagus? A randomized phase II trial
-
Burmeister BH, Thomas JM, Burmeister EA, et al. Is concurrent radiation therapy required in patients receiving chemotherapy for adenocarcinoma of the oesophagus? A randomized phase II trial. Eur J Cancer. 2011;47:354-60.
-
(2011)
Eur J Cancer
, vol.47
, pp. 354-360
-
-
Burmeister, B.H.1
Thomas, J.M.2
Burmeister, E.A.3
-
11
-
-
78650167757
-
Effect of preoperative concurrent chemoradiotherapy on survival of patients with resectable esophageal or esophagogastric junction cancer: Results from a multicenter randomized phase III study
-
(suppl; abstr 4004
-
Gaast AV, Van Hagen P, Hulshof D, et al. Effect of preoperative concurrent chemoradiotherapy on survival of patients with resectable esophageal or esophagogastric junction cancer: Results from a multicenter randomized phase III study. J Clin Oncol. 2010;28:15s (suppl; abstr 4004).
-
(2010)
J Clin Oncol.
, vol.28
-
-
Gaast, A.V.1
Van Hagen, P.2
Hulshof, D.3
-
12
-
-
38049047178
-
Capecitabine and oxaliplatin for advanced esophagogastric cancer
-
Cunningham D, Starling N, Rao S, et al. Capecitabine and oxaliplatin for advanced esophagogastric cancer. N Eng J Med. 2008;358:36-46.
-
(2008)
N Eng J Med.
, vol.358
, pp. 36-46
-
-
Cunningham, D.1
Starling, N.2
Rao, S.3
-
13
-
-
79953027573
-
Effectiveness and safety of oxaliplatin compared to cisplatin for advanced, unresectable gastric cancer: A systematic review and meta-analysis
-
This review suggests that oxaliplatin provides greater efficacy with less toxicity than cisplatin in patients with metastatic gastric and gastroesophageal junction adenocarcinoma
-
• Montagnani F, Turrisi G, Marinozzi C, et al. Effectiveness and safety of oxaliplatin compared to cisplatin for advanced, unresectable gastric cancer: A systematic review and meta-analysis. Gastric Cancer. 2011;14:50-5. This review suggests that oxaliplatin provides greater efficacy with less toxicity than cisplatin in patients with metastatic gastric and gastroesophageal junction adenocarcinoma.
-
(2011)
Gastric Cancer.
, vol.14
, pp. 50-55
-
-
Montagnani, F.1
Turrisi, G.2
Marinozzi, C.3
-
14
-
-
78049279299
-
Phase II randomized trial of chemoradiotherapy with FOLFOX4 or cisplatin plus fluorouracil in esophageal cancer
-
This phase II study suggests that concurrent chemoradiotherapy with FOLFOX4 provides a similar degree of benefit as the combination of cisplatin and 5FU
-
• Conroy T, Yataghene Y, Etienne PL, et al. Phase II randomized trial of chemoradiotherapy with FOLFOX4 or cisplatin plus fluorouracil in esophageal cancer. Br J Cancer. 2010;103:1349-55. This phase II study suggests that concurrent chemoradiotherapy with FOLFOX4 provides a similar degree of benefit as the combination of cisplatin and 5FU.
-
(2010)
Br J Cancer.
, vol.103
, pp. 1349-1355
-
-
Conroy, T.1
Yataghene, Y.2
Etienne, P.L.3
-
15
-
-
83355163397
-
S0356: A phase II clinical and prospective molecular trial with oxaliplatin, fluorouracil, and external-beam radiation therapy before surgery for patients with esophageal adenocarcinoma
-
Leichman LP, Goldman BH, Bohanes PO, et al. S0356: A phase II clinical and prospective molecular trial with oxaliplatin, fluorouracil, and external-beam radiation therapy before surgery for patients with esophageal adenocarcinoma. J Clin Oncol. 2011;29:4555-60.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4555-4560
-
-
Leichman, L.P.1
Goldman, B.H.2
Bohanes, P.O.3
-
16
-
-
77954952497
-
7th edition of the AJCC cancer staging manual: Esophagus and esophagogastric junction
-
Rice TW, Blackstone EH, Rusch VW. 7th edition of the AJCC cancer staging manual: Esophagus and esophagogastric junction. Ann Surg Oncol. 2010;17:1721-4.
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 1721-1724
-
-
Rice, T.W.1
Blackstone, E.H.2
Rusch, V.W.3
-
17
-
-
77956851247
-
Against cancer cancer staging manuals
-
Cancer of the esophagus and esophagogastric junction: Data-driven staging for the seventh edition of the american joint committee on cancerinternational union
-
Rice TW, Rusch VW, Ishwaran H, et al. Cancer of the esophagus and esophagogastric junction: Data-driven staging for the seventh edition of the American Joint Committee on Cancer/International Union Against Cancer Cancer Staging Manuals. Cancer. 2010;116:3763-73.
-
(2010)
Cancer.
, vol.116
, pp. 3763-3773
-
-
Rice, T.W.1
Rusch, V.W.2
Ishwaran, H.3
-
18
-
-
58149399165
-
Predicting systemic disease in patients with esophageal cancer after esophagectomy: A multinational study on the significance of the number of involved lymph nodes
-
Peyre CG, Hagen JA, DeMeester SR, et al. Predicting systemic disease in patients with esophageal cancer after esophagectomy: A multinational study on the significance of the number of involved lymph nodes. Ann Surg. 2008;248:979-85.
-
(2008)
Ann Surg
, vol.248
, pp. 979-985
-
-
Peyre, C.G.1
Hagen, J.A.2
DeMeester, S.R.3
-
19
-
-
77956282459
-
Ratio of metastatic lymph nodes to total number of nodes resected is prognostic for survival in esophageal carcinoma
-
Kelty CJ, Kennedy CW, Falk GL. Ratio of metastatic lymph nodes to total number of nodes resected is prognostic for survival in esophageal carcinoma. J Thorac Oncol. 2010;5:1467-71.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1467-1471
-
-
Kelty, C.J.1
Kennedy, C.W.2
Falk, G.L.3
-
20
-
-
33847022740
-
The utility of positron emission tomography in staging of potentially operable carcinoma of the thoracic esophagus: Results of the American College of Surgeons Oncology Group Z0060 trial
-
Meyers BF, Downey RJ, Decker PA, et al. The utility of positron emission tomography in staging of potentially operable carcinoma of the thoracic esophagus: Results of the American College of Surgeons Oncology Group Z0060 trial. J Thorac Cardiovascular Surg. 2007;133:738-45.
-
(2007)
J Thorac Cardiovascular Surg
, vol.133
, pp. 738-745
-
-
Meyers, B.F.1
Downey, R.J.2
Decker, P.A.3
-
21
-
-
33645468927
-
Predictive value of 18-fluoro-deoxy-glucose-positron emission tomography ([18] F FDG-PET) in the identification of responders to chemoradiation therapy for the treatment of locally advanced esophageal cancer
-
Levine EA, Farmer MR, Clark P, et al. Predictive value of 18-fluoro-deoxy-glucose-positron emission tomography ([18] F FDG-PET) in the identification of responders to chemoradiation therapy for the treatment of locally advanced esophageal cancer. Ann Surg. 2006;243:472-8.
-
(2006)
Ann Surg.
, vol.243
, pp. 472-478
-
-
Levine, E.A.1
Farmer, M.R.2
Clark, P.3
-
22
-
-
78149325746
-
Outcomes of patients with esophageal cancer staged with [18F] fluorodeoxyglucose positron emission tomography (FDG-PET): Can post chemoradiotherapy FDG-PET predict the utility of resection?
-
This retrospective study suggests that patients with a negative FDG-PET after definitive concurrent chemoradiotherapy have improved survival compared with patients who have residual FDG uptake
-
• Monjazeb AM, Riedlinger G, Aklilu M, et al. Outcomes of patients with esophageal cancer staged with [18F] Fluorodeoxyglucose positron emission tomography (FDG-PET): Can post chemoradiotherapy FDG-PET predict the utility of resection? J Clin Oncol. 2010;28:4714-21. This retrospective study suggests that patients with a negative FDG-PET after definitive concurrent chemoradiotherapy have improved survival compared with patients who have residual FDG uptake.
-
(2010)
J Clin Oncol.
, vol.28
, pp. 4714-4721
-
-
Monjazeb, A.M.1
Riedlinger, G.2
Aklilu, M.3
-
23
-
-
33750578261
-
Metabolic imaging predicts response, survival, and recurrence in adenocarcinomas of the esophagogastric junction
-
DOI 10.1200/JCO.2006.06.7801
-
Ott K, Weber WA, Lordick F, et al. Metabolic imaging predicts response, survival, and recurrence in adenocarcinomas of the esophagogastric junction. J Clin Oncol. 2006;24:4692-8. (Pubitemid 46646244)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.29
, pp. 4692-4698
-
-
Ott, K.1
Weber, W.A.2
Lordick, F.3
Becker, K.4
Busch, R.5
Herrmann, K.6
Wieder, H.7
Fink, U.8
Schwaiger, M.9
Siewert, J.-R.10
-
24
-
-
34548185461
-
PET to assess early metabolic response and to guide treatment of adenocarcinoma of the oesophagogastric junction: The MUNICON phase II trial
-
DOI 10.1016/S1470-2045(07)70244-9, PII S1470204507702449
-
Lordick F, Ott K, Krause BJ, et al. PET to assess early metabolic response and to guide treatment of adenocarcinoma of the oesphagogastric junction: The MUNICON phase II trial. Lancet Oncol. 2007;8:797-805. (Pubitemid 47308659)
-
(2007)
Lancet Oncology
, vol.8
, Issue.9
, pp. 797-805
-
-
Lordick, F.1
Ott, K.2
Krause, B.-J.3
Weber, W.A.4
Becker, K.5
Stein, H.J.6
Lorenzen, S.7
Schuster, T.8
Wieder, H.9
Herrmann, K.10
Bredenkamp, R.11
Hofler, H.12
Fink, U.13
Peschel, C.14
Schwaiger, M.15
Siewert, J.R.16
-
25
-
-
80051703750
-
F-FDG PET-guided salvage neoadjuvant radiochemotherapy of adenocarcinoma of the esophagogastric junction: The MUNICON II trial
-
This is a phase II study that employs salvage preoperative chemoradiotherapy in patients who do not demonstrate an early response by FDG-PET to induction chemotherapy
-
• Meyer zum Buschenfelde C, Herrmann K, Schuster T, et al. F-FDG PET-guided salvage neoadjuvant radiochemotherapy of adenocarcinoma of the esophagogastric junction: The MUNICON II trial. J Nucl Med. 2011;52:1189-96. This is a phase II study that employs salvage preoperative chemoradiotherapy in patients who do not demonstrate an early response by FDG-PET to induction chemotherapy.
-
(2011)
J Nucl Med.
, vol.52
, pp. 1189-1196
-
-
Meyer Zum Buschenfelde, C.1
Herrmann, K.2
Schuster, T.3
-
26
-
-
2342437556
-
Epidermal growth factor receptor expression correlates with histologic grade in resected esophageal adenocarcinoma
-
DOI 10.1016/j.gassur.2004.01.006, PII S1091255X04000861
-
Wilkinson NW, Black JD, Roukhadze E, et al. Epidermal growth factor receptor expression correlates with histologic grade in resected esophageal adenocarcinoma. J Gastrointest Surg. 2004;8:448-53. (Pubitemid 38561209)
-
(2004)
Journal of Gastrointestinal Surgery
, vol.8
, Issue.4
, pp. 448-453
-
-
Wilkinson, N.W.1
Black, J.D.2
Roukhadze, E.3
Driscoll, D.4
Smiley, S.5
Hoshi, H.6
Geradts, J.7
Javle, M.8
Brattain, M.9
-
27
-
-
33846928248
-
Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adenocarcinomas: Association with poor outcome
-
DOI 10.1002/cncr.22445
-
Wang KL, Wu T, In SC, et al. Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adenocarcinomas: Association with poor outcome. Cancer. 2007;109:658-67. (Pubitemid 46233226)
-
(2007)
Cancer
, vol.109
, Issue.4
, pp. 658-667
-
-
Wang, K.L.1
Wu, T.-T.2
In, S.C.3
Wang, H.4
Reseetkova, E.5
Correa, A.M.6
Hofstetter, W.L.7
Swisher, S.G.8
Ajani, J.A.9
Rashid, A.10
Albarracin, C.T.11
-
28
-
-
23044479392
-
Diffuse EGFR staining is associated with reduced overall survival in locally advanced oesophageal squamous cell cancer
-
DOI 10.1038/sj.bjc.6602625
-
Gibault L, Metges JP, Conan-Charlet V, et al. Diffuse EGFR staining is associated with a reduced overall survival in locally advanced oesphageal squamous cell cancer. Br J Cancer. 2005;93:107-15. (Pubitemid 41076258)
-
(2005)
British Journal of Cancer
, vol.93
, Issue.1
, pp. 107-115
-
-
Gibault, L.1
Metges, J.-P.2
Conan-Charlet, V.3
Lozac'h, P.4
Robaszkiewicz, M.5
Bessaguet, C.6
Lagarde, N.7
Volant, A.8
-
29
-
-
31844432805
-
EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus
-
Hanawa M, Suzuki S, Dobashi Y, et al. EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagus. Int J Cancer. 2005;118:1173-80.
-
(2005)
Int J Cancer.
, vol.118
, pp. 1173-1180
-
-
Hanawa, M.1
Suzuki, S.2
Dobashi, Y.3
-
30
-
-
84866733910
-
A phase II trial of gefitinib for recurrent or metastatic cancer of the esophagus or gastroesophageal junction
-
[Epub ahead of print]
-
Adelstein DJ, Rodriguez CP, Rybicki LA, et al. A phase II trial of gefitinib for recurrent or metastatic cancer of the esophagus or gastroesophageal junction. Invest New Drugs 2011, [Epub ahead of print].
-
(2011)
Invest New Drugs
-
-
Adelstein, D.J.1
Rodriguez, C.P.2
Rybicki, L.A.3
-
31
-
-
33750618860
-
Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127
-
Dragovich T, McCoy S, Fenoglio-Preiser CM, et al. Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127. J Clin Oncol. 2006;24:4922-6.
-
(2006)
J Clin Oncol.
, vol.24
, pp. 4922-4926
-
-
Dragovich, T.1
McCoy, S.2
Fenoglio-Preiser, C.M.3
-
32
-
-
79952847624
-
A phase II trial of erlotinib in patients with previously treated squamous cell and adenocarcinoma of the esophagus
-
Ilson DH, Kelsen D, Shah M, et al. A phase II trial of erlotinib in patients with previously treated squamous cell and adenocarcinoma of the esophagus. Cancer. 2011;117:1409-14.
-
(2011)
Cancer.
, vol.117
, pp. 1409-1414
-
-
Ilson, D.H.1
Kelsen, D.2
Shah, M.3
-
33
-
-
77649085714
-
A phase II study of perioperative concurrent chemotherapy, gefitinib, and hyperfractionated radiation followed by maintenance gefitinib in locoregionally advanced esophagus and gastroesophageal junction cancer
-
Rodriguez CP, Adelstein DJ, Rice TW, et al. A phase II study of perioperative concurrent chemotherapy, gefitinib, and hyperfractionated radiation followed by maintenance gefitinib in locoregionally advanced esophagus and gastroesophageal junction cancer. J Thorac Oncol. 2010;5:229-35.
-
(2010)
J Thorac Oncol.
, vol.5
, pp. 229-235
-
-
Rodriguez, C.P.1
Adelstein, D.J.2
Rice, T.W.3
-
34
-
-
80052439302
-
Phase II trial of modified FOLFOX6 and erlotinib in patients with metastatic or advanced adenocarcinoma of the oesophagus and gastro-oesophageal junction
-
Wainberg ZA, Lin L-S, DiCarlo B, et al. Phase II trial of modified FOLFOX6 and erlotinib in patients with metastatic or advanced adenocarcinoma of the oesophagus and gastro-oesophageal junction. Br J Cancer. 2011;105:760-5.
-
(2011)
Br J Cancer.
, vol.105
, pp. 760-765
-
-
Wainberg, Z.A.1
Lin, L.-S.2
DiCarlo, B.3
-
35
-
-
77956267602
-
Cetuximab as second-line therapy in patients with metastatic esophageal adenocarcinoma: A phase II southwest oncology group study (S0415
-
Gold PJ, Goldman B, Iqbal S, et al. Cetuximab as second-line therapy in patients with metastatic esophageal adenocarcinoma: A phase II southwest oncology group study (S0415). J Thorac Oncol. 2010;5:1472-6.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1472-1476
-
-
Gold, P.J.1
Goldman, B.2
Iqbal, S.3
-
36
-
-
70349641356
-
Cetuximab plus cisplatin-5-flourouracil versus cisplatin-5-flourouracil alone in first-line metastatic squamous cell carcinoma of the esophagus: A randomized phase II study of the Arbeitsgemeinschaft Internistische Onkologie
-
Lorenzen S, Schuster T, Porschen R, et al. Cetuximab plus cisplatin-5-flourouracil versus cisplatin-5-flourouracil alone in first-line metastatic squamous cell carcinoma of the esophagus: A randomized phase II study of the Arbeitsgemeinschaft Internistische Onkologie. Ann Oncol. 2009;20:1667-73.
-
(2009)
Ann Oncol
, vol.20
, pp. 1667-1673
-
-
Lorenzen, S.1
Schuster, T.2
Porschen, R.3
-
37
-
-
79952075689
-
Cetuximab in combination with chemoradiotherapy before surgery in patients with resectable, locally advanced esophageal carcinoma: A prospective, multicenter phase Ib/II trial (SAKK75/06
-
Ruhstaller T, Pless M, Dietrich D, et al. Cetuximab in combination with chemoradiotherapy before surgery in patients with resectable, locally advanced esophageal carcinoma: A prospective, multicenter phase Ib/II trial (SAKK75/06). J Clin Oncol. 2011;29:626-31.
-
(2011)
J Clin Oncol
, vol.29
, pp. 626-631
-
-
Ruhstaller, T.1
Pless, M.2
Dietrich, D.3
-
38
-
-
79551583770
-
A multicenter phase II study of induction chemotherapy with FOLFOX-4 and cetuximab followed by radiation and cetuximab in locally advanced oesophageal cancer
-
De Vita F, Orditura M, Martinelli E, et al. A multicenter phase II study of induction chemotherapy with FOLFOX-4 and cetuximab followed by radiation and cetuximab in locally advanced oesophageal cancer. Br J Cancer. 2011;104:427-32.
-
(2011)
Br J Cancer.
, vol.104
, pp. 427-432
-
-
De Vita, F.1
Orditura, M.2
Martinelli, E.3
-
39
-
-
84866729919
-
Clinicopathologic features and treatment outcomes of patients (pts) with HER2-positive (pos) adenocarcinomas (ACA) of the esophagus (E) and gastroesophageal junction (GEJ
-
(suppl; abstr 4046
-
Phillips BE, Tubbs RR, Rice TW, et al. Clinicopathologic features and treatment outcomes of patients (pts) with HER2-positive (pos) adenocarcinomas (ACA) of the esophagus (E) and gastroesophageal junction (GEJ). J Clin Oncol 2011;29 (suppl; abstr 4046).
-
(2011)
J Clin Oncol
, pp. 29
-
-
Phillips, B.E.1
Tubbs, R.R.2
Rice, T.W.3
-
40
-
-
78650359655
-
Expression of Her-2 in carcinomas of the esophagus
-
Schoppmann SF, Jesch B, Friedrich J, et al. Expression of Her-2 in carcinomas of the esophagus. Am J Surg Pathol. 2010;34:1868-73.
-
(2010)
Am J Surg Pathol
, vol.34
, pp. 1868-1873
-
-
Schoppmann, S.F.1
Jesch, B.2
Friedrich, J.3
-
41
-
-
79959928931
-
Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: Summary of a revised immunohistochemical evaluation system, bright field double in situ hybridization and fluorescence in situ hybridization
-
Langer R, Rauser S, Feith M, et al. Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: Summary of a revised immunohistochemical evaluation system, bright field double in situ hybridization and fluorescence in situ hybridization. Mod Pathol. 2011;24:908-16.
-
(2011)
Mod Pathol
, vol.24
, pp. 908-916
-
-
Langer, R.1
Rauser, S.2
Feith, M.3
-
42
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastrooesophageal junction cancer (ToGA): A phase 3, open-label, randomized controlled trial
-
This study demonstrates that the addition of trastuzumab to chemotherapy provides a survival advantage for patients with metastatic gastric and gastroesophageal adenocarcinoma who express HER2
-
•• Bang Y, Van Cutsem E, Feyereislova A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastrooesophageal junction cancer (ToGA): A phase 3, open-label, randomized controlled trial. Lancet. 2010;376:687-97. This study demonstrates that the addition of trastuzumab to chemotherapy provides a survival advantage for patients with metastatic gastric and gastroesophageal adenocarcinoma who express HER2.
-
(2010)
Lancet.
, vol.376
, pp. 687-697
-
-
Bang, Y.1
Van Cutsem, E.2
Feyereislova, A.3
-
43
-
-
33846227021
-
Phase I/II study of trastuzumab, paclitaxel, cisplatin and radiation for locally advanced, HER2 overexpressing, esophageal adenocarcinoma
-
DOI 10.1016/j.ijrobp.2006.08.076, PII S036030160602832X
-
Safran H, DiPetrillo T, Akerman P, et al. PhaseI/II study of trastuzumab, paclitaxel, cisplatin, and radiation for locally advanced, Her2 overexpressing, esophageal adenocarcinoma. Int J Radiation Oncology Biol Phys. 2007;67:405-9. (Pubitemid 46108313)
-
(2007)
International Journal of Radiation Oncology Biology Physics
, vol.67
, Issue.2
, pp. 405-409
-
-
Safran, H.1
DiPetrillo, T.2
Akerman, P.3
Ng, T.4
Evans, D.5
Steinhoff, M.6
Benton, D.7
Purviance, J.8
Goldstein, L.9
Tantravahi, U.10
Kennedy, T.11
-
44
-
-
70349937924
-
Phase II study of cetuximab in combination with cisplatin and docetaxel in patients with untreated advanced gastric or gastro-oesophageal junction adenocarcinoma (DOCETUX study
-
Pinto C, Di Fabio F, Barone C, et al. Phase II study of cetuximab in combination with cisplatin and docetaxel in patients with untreated advanced gastric or gastro-oesophageal junction adenocarcinoma (DOCETUX study). Br J Cancer. 2009;101:1261-8.
-
(2009)
Br J Cancer.
, vol.101
, pp. 1261-1268
-
-
Pinto, C.1
Di Fabio, F.2
Barone, C.3
-
45
-
-
79957834501
-
A multicenter phase II trial of single-agent cetuximab in advanced esophageal and gastric adenocarcinoma
-
Chan JA, Blaszkowsky LS, Enzinger PC, et al. A multicenter phase II trial of single-agent cetuximab in advanced esophageal and gastric adenocarcinoma. Ann Oncol. 2011;22:1367-73.
-
(2011)
Ann Oncol.
, vol.22
, pp. 1367-73
-
-
Chan, J.A.1
Blaszkowsky, L.S.2
Enzinger, P.C.3
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