Folic acid reverses nitric oxide synthase uncoupling and prevents cardiac dysfunction in insulin resistance: Role of Ca2+/calmodulin-activated protein kinase II

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 234-243

  Roe, Nathan D ^a   He, Emily Y ^a,b   Wu, Zhenbiao ^b   Ren, Jun ^a  

^a UNIVERSITY OF WYOMING   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Ca 2+; CaMKII; Cardiac function; Folic acid; Free radicals; Insulin resistance; Intracellular

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM ION; FOLIC ACID; GLUCOSE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; RYANODINE RECEPTOR; RYANODINE RECEPTOR 2; STARCH; SUCROSE; SUPEROXIDE; VITAMIN B COMPLEX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HEART DISEASE; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; INSULIN RESISTANCE; M MODE ECHOCARDIOGRAPHY; MOUSE; NONHUMAN; OXIDATIVE COUPLING; OXIDATIVE STRESS; PRIORITY JOURNAL; TREATMENT DURATION; WESTERN BLOTTING; ANIMAL; DISEASE MODEL; DRUG EFFECTS; HEART CONTRACTION; HEART MUSCLE; METABOLISM; PHYSIOLOGY;

ANIMALS; BLOTTING, WESTERN; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; DISEASE MODELS, ANIMAL; FOLIC ACID; INSULIN RESISTANCE; MICE; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; NITRIC OXIDE SYNTHASE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; VITAMIN B COMPLEX;

EID: 84884559944     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.06.042     Document Type: Article

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