Remarkable disparity in mechanical response among the extracellular domains of type i and II cadherins

Journal of Biomolecular Structure and Dynamics

Volumn 31, Issue 10, 2013, Pages 1137-1149

  Liu, Ruchuan ^a,b   Wu, Fei ^b   Thiery, Jean Paul ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

AFM force mode; calcium bridge; cell adhesion; classical type I cadherins; classical type II cadherins; conformational dynamics; E cadherin; elasticity; homophilic interaction; intermediate state; single molecule force spectroscopy; SMD simulation; unfolding

Indexed keywords

CADHERIN; CALCIUM ION; DIMER; TYPE I CADHERIN; TYPE II CADHERIN; UNCLASSIFIED DRUG; UVOMORULIN;

ARTICLE; ATOMIC FORCE MICROSCOPY; CELL ADHESION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN UNFOLDING;

CADHERINS; CALCIUM; MICROSCOPY, ATOMIC FORCE; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN UNFOLDING;

EID: 84884553251     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2012.726530     Document Type: Article

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