Migraine in gulf war illness and chronic fatigue syndrome: Prevalence, potential mechanisms, and evaluation

Frontiers in Physiology

Volumn 4 JUL, Issue , 2013, Pages

  Rayhan, Rakib U ^a   Ravindran, Murugan K ^a   Baraniuk, James N ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Central sensitization; Chronic fatigue syndrome; Chronic pain; Fatigue; Fibromyalgia; Gulf war illness; Migraine; Neurolimbic pathway

Indexed keywords

ADULT; ARTICLE; CHRONIC FATIGUE SYNDROME; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROMYALGIA; HUMAN; HYPERALGESIA; MALE; MCGILL PAIN QUESTIONNAIRE; MIGRAINE; MIGRAINE WITH AURA; MIGRAINE WITHOUT AURA; PAIN ASSESSMENT; PERSIAN GULF SYNDROME; PREVALENCE; SELF REPORT; SHORT FORM 36; TENSION HEADACHE;

EID: 84884545808     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2013.00181     Document Type: Article

References (85)

1. Aurora, S. K. (2009). Spectrum of illness: understanding biological patterns and relationships in chronic migraine. Neurology 72(Suppl. 5), S8-S13. doi: 10.1212/WNL.0b013e31819749fd
2. Ayata, C. (2010). Cortical spreading depression triggers migraine attack. Headache 50, 725-730. doi: 10.1111/j.1526-4610.2010.01647.x
3. Baraniuk, J. N., Adewuyi, O., Merck, S. J., Ali, M., Ravindran, M. K., Timbol, C. R., et al. (2013). A Chronic Fatigue Syndrome (CFS) severity score based on case designation criteria. Am. J. Transl. Res. 1, 53-68.
4. Baraniuk, J. N., Petrie, K. N., Le, U., Tai, C.-F., Park, Y.-J., Yuta, A., et al. (2005). Neuropathology in rhinosinusitis. Am. J. Respir. Crit. Care Med. 171, 5-11. doi: 10.1164/rccm.200403-357OC
5. Baraniuk, J. N., and Zheng, Y. (2010). Relationships among rhinitis, fibromyalgia, and chronic fatigue. Allergy Asthma Proc. 3, 169-178. doi: 10.2500/aap.2010.31.3311
6. Barnden, L. R., Crouch, B., Kwiatek, R., Burnet, R., Mernone, A., Chryssidis, S., et al. (2011). A brain MRI study of chronic fatigue syndrome: evidence of brainstem dysfunction and altered homeostasis. NMR Biomed. 10, 1302-1312. doi: 10.1002/nbm.1692
7. Bartsch, T., Knight, Y. E., and Goadsby, P. J. (2004). Activation of 5-HT1B/1D receptors in the periaqueductal grey inhibits meningeal nociception. Ann. Neurol. 56, 371-381. doi: 10.1002/ana.20193
8. Bradley, L. A. (2008). Pathophysiologic mechanisms of fibromyalgia and its related disorders. J. Clin. Psychiatry 69(Suppl. 2), S6-S13.
9. Buchwald, D., Pearlman, T., Umali, J., Schmaling, K., and Katon, W. (1996). Functional status in patients with chronic fatigue syndrome, other fatiguing illnesses, and healthy individuals. Am. J. Med. 4, 364-370. doi: 10.1016/S0002-934300234-3
10. Burgmer, M., Gaubitz, M., Konrad, C., Wrenger, M., Hilgart, S., Heuft, G., et al. (2009). Decreased gray matter volumes in the cingulo-frontal cortex and the amygdala in patients with fibromyalgia. Psychosom. Med. 5, 192-199.
11. Burstein, R., and Jakubowski, M. (2005). Unitary hypothesis for multiple triggers of the pain and strain of migraine. J. Comp. Neurol. 493, 9-14.
12. Burstein, R., Jakubowski, M., Garcia-Nicas, E., Kainz, V., Bajwa, Z., Hargreaves, R., et al. (2010). Thalamic sensitization transforms localized pain into widespread allodynia. Ann. Neurol. 68, 81-91. doi: 10.1002/ana.21994
13. Casado, B., Pannell, L. K., Whalen, G., Clauw, D. J., and Baraniuk, J. N. (2005). Human neuroglobin protein in cerebrospinal fluid. BMC Proteome Sci. 3:2. doi: 10.1186/1477-5956-3-2
14. Charles, A., (2010). Does cortical spreading depression initiate a migraine attack. Maybe not. Headache 50, 731-733. doi: 10.1111/j.1526-4610.2010.01646.x
15. Critchley, H. D., and Harrison, N. A. (2013). Visceral influences on brain and behavior. Neuron 77, 624-638. doi: 10.1016/j.neuron.2013. 02.008
16. DaSilva, A. F., Granziera, C., Tuch, D. S., Snyder, J., Vincent, M., and Hadjikhani, N. (2007). Interictal alterations of the trigeminal somatosensory pathway and periaqueductal gray matter in migraine. Neuroreport 4, 301-305. doi: 10.1097/WNR.0b013e32801776bb
17. de Tommaso, M., Federici, A., Serpino, C., Vecchio, E., Franco, G., Sardaro, M., et al. (2011). Clinical features of headache patients with fibromyalgia comorbidity. J. Headache Pain 6, 629-638. doi: 10.1007/s10194-011-0377-6
18. Eikermann-Haerter, K., and Ayata, C. (2010). Cortical spreading depression and migraine. Curr. Neurol. Neurosci. Rep. 10, 167-173. doi: 10.1007/s11910-010-0099-1
19. Eisen, S. A., Kang, H. K., Murphy, F. M., Blanchard, M. S., and Reda, D. J. (2005). Gulf war study participating investigators. Gulf War veterans' health: medical evaluation of a US cohort. Ann. Intern. Med. 11, 881-890. doi: 10.7326/0003-4819-142-11-200506070-00005
20. Fabricius, M., Fuhr, S., Bhatia, R., Boutelle, M., Hashemi, P., Strong, A. J., et al. (2006). Cortical spreading depression and peri-infarct depolarization in acutely injured human cerebral cortex. Brain 129, 778-790. doi: 10.1093/brain/awh716
21. Freeman, G. H., and Halton, J. H. (1951). Note on exact treatment of contingency, goodness of fit and other problems of significance. Biometrika 38, 141-149.
22. Fukuda, K., Nisenbaum, R., Stewart, G., Thompson, W. W., Robin, L., Washko, R. M., et al. (1998). Chronic multisymptom illness affecting air force veterans of the gulf war. JAMA 280, 981-988. doi: 10.1001/jama.280.11.981
23. Fukuda, K., Straus, S. E., Hickie, I., Sharpe, M. C., Dobbins, J. G., and Komaroff, A. (1994). The chronic fatigue syndrome: a comprehensive approach to its definition and study. The International Chronic Fatigue Syndrome Study Group. Ann. Intern. Med. 121, 953-959. doi: 10.7326/0003-4819-121-12-199412150-199400009
24. Fukui, P. T., Goncalves, T. R., Strabelli, C. G., Lucchino, N. M., Matos, F. C., Santos, J. P., et al. (2008). Trigger factors in migraine patients. Arq. Neuropsiquatr. 66, 494-499. doi: 10.1590/S0004-282X2008000400011
25. Gebhart, G. F. (2004). Descending modulation of pain. Neurosci. Biobehav. Rev. 27, 729-737. doi: 10.1016/j.neubiorev.2003.11.008
26. Goadsby, P. J., and Gundlach, A. L. (1991). Localization of [3H]-dihydroergotamine binding sites in the cat central nervous system: relevance to migraine. Ann. Neurol. 29, 91-94.
27. Goadsby, P. J., Lipton, R. B., and Ferrari, M. D. (2002). Migraine-current understanding and treatment. N. Engl. J. Med. 346, 257-270. doi: 10.1056/NEJMra010917
28. Gray, G. C., Reed, R. J., Kaiser, K. S., Smith, T. C., and Gastañaga, V. M. (2002). Self-reported symptoms and medical conditions among 11, 868 Gulf War-era veterans: the Seabee Health Study. Am. J. Epidemiol. 11, 1033-1044.
29. Headache Classification Subcommittee of the International Headache Society. (2004). The international classification of headache disorders: 2nd edition. Cephalalgia 24(Suppl. 1), 9-160.
30. Holroyd, K. A., Cottrell, C. K., O'Donnell, F. J., Cordingley, G. E., Drew, J. B., Carlson, B. W., et al. (2010). Effect of preventive (beta blocker) treatment, behavioural migraine management, or their combination on outcomes of optimized acute treatment in frequent migraine: randomised controlled trial. BMJ 341:c4871. doi: 10.1136/bmj.c4871
31. Holroyd, K. A., Labus, J. S., and Carlson, B. (2009). Moderation and mediation in the psychological and drug treatment of chronic tension-type headache: the role of disorder severity and psychiatric comorbidity. Pain 143, 213-222. doi: 10.1016/j.pain.2009.02.019
32. Jensen, K. B., Kosek, E., Petzke, F., Carville, S., Fransson, P., Marcus, H., et al. (2009). Evidence of dysfunctional pain inhibition in fibromyalgia reflected in rACC during provoked pain. Pain 144, 95-100. doi: 10.1016/j.pain.2009.03.018
33. Jones, J. F., Lin, J. M., Maloney, E. M., Boneva, R. S., Nater, U. M., Unger, E. R., et al. (2009). An evaluation of exclusionary medical/psychiatric conditions in the definition of chronic fatigue syndrome. BMC Med. 7:57. doi: 10.1186/1741-7015-7-57
34. Karatas, H., Erdener, S. E., Gursoy-Ozdemir, Y., Lule, S., Eren-Koçak, E., Sen, Z. D., et al. (2013). Spreading depression triggers headache by activating neuronal Panx1 channels. Science 6123, 1092-1095. doi: 10.1126/science.1231897
35. Kruit, M. C., Launer, L. J., Overbosch, J., van Buchem, M. A., and Ferrari, M. D. (2009). Iron accumulation in deep brain nuclei in migraine: a population-based magnetic resonance imaging study. Cephalalgia 29, 351-359. doi: 10.1111/j.1468-2982.2008.01723.x
36. Latremoliere, A., and Woolf, C. J. (2009). Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J. Pain 10, 895-926. doi: 10.1016/j.jpain.2009.06.012
37. Lea, R., Hopkins, V., Hastleton, J., Houghton, L. A., and Whorwell, P. J. (2004). Diagnostic criteria for irritable bowel syndrome: utility and applicability in clinical practice. Digestion 70, 210-213. doi: 10.1159/000082891
38. Lebel, A., Maleki, N., Drosos, A., Guydon, A., Mattell, D., and Martonee, G. (2011). Alterations with PAG connectivity in children vs adults with episodic migraine. (Abstract). Headache 51(Suppl. 1), 46-47.
39. Li, B., Mahan, C. M., Kang, H. K., Eisen, S. A., and Engel, C. C. (2011). Longitudinal health study of US (1991). Gulf War veterans: changes in health status at 10-year follow-up. Am. J. Epidemiol. 761-768. doi: 10.1093/aje/kwr154
40. Lipton, R. B. (2009). Tracing transformation: chronic migraine classification, progression, and epidemiology. Neurology 72(Suppl. 5), S3-S7. doi: 10.1212/WNL.0b013e3181974b19
41. Lipton, R. B., Silberstein, S. D., Saper, J. R., Bigal, M. E., and Goadsby, P. J. (2003). Why headache treatments fail. Neurology 60, 1064-1070. doi: 10.1212/01.WNL.0000052687.03646.74
42. Lutz, J., Jäger, L., de Quervain, D., Krauseneck, T., Padberg, F., Wichnalek, M., et al. (2008). White and gray matter abnormalities in the brain of patients with fibromyalgia: a diffusion-tensor and volumetric imaging study. Arthritis Rheum. 12, 3960-3969. doi: 10.1002/art.24070
43. Mainero, C., Boshyan, J., and Hadjikhani, N. (2011). Altered functional magnetic resonance imaging resting-state connectivity in periaqueductal gray networks in migraine. Ann. Neurol. 70, 838-845. doi: 10.1002/ana.22537
44. Maizels, M., Aurora, S., and Heinricher, M. (2012). Beyond Neurovascular: migraine as a dysfunctional neurolimbic pain network. Headache 52, 1553-1565. doi: 10.1111/j.1526-4610.2012.02209.x
45. Maizels, M., and Burchette, R. (2004). Somatic symptoms in headache patients: the influence of headache diagnosis, frequency, and comorbidity. Headache 44, 983-993. doi: 10.1111/j.1526-4610.2004.04192.x
46. Maleki, N., Nutile, L., Pendee, G., Lebel, A., Drosos, A., and Deniel, R. G. (2011a). Novel findings within basal ganglia in episodic migraine (Abstract). Headache 51 (Suppl. 1), 5.
47. Maleki, N., Linnman, C., Burstein, R., Becerra, L., and Borsook, D. (2011b). Gender-related differences in periaqueductal gray functioning in episodic migraineurs. (Abstract). Headache 51(Suppl. 1), 40-41.
48. Malick, A., and Burstein, R. (2000). Peripheral and central sensitization during migraine. Funct. Neurol. 15(Suppl. 3), 28-35.
49. May, A. (2009). New insights into headache: an update on functional and structural imaging findings. Nat. Rev. Neurol. 5, 199-209. doi: 10.1038/nrneurol.2009.28
50. Meeus, M., and Nijs, J. (2007). Central sensitization: a biopsychosocial explanation for chronic widespread pain in patients with fibromyalgia and chronic fatigue syndrome. Clin. Rheumatol. 26, 465-473. doi: 10.1007/s10067-006-0433-9
51. Melzack, R. (1987). The short-form McGill pain questionnaire. Pain 30, 191-197. doi: 10.1016/0304-395991074-8
52. Naranch, K., Park, Y. J., Repka-Ramirez, M. S., Velarde, A., and Clauw, D. (2002). A tender sinus does not always mean rhinosinusitis. Otolaryngol. Head Neck Surg. 127, 387-397.
53. Noseda, R., Jakubowski, M., Kainz, V., Borsook, D., and Burstein, R. (2011). Cortical projections of functionally identified thalamic trigeminovascular neurons: implications for migraine headache and its associated symptoms. J. Neurosci. 4, 14204-14217.
54. Obermann, M., Pleger, B., de Greiff, A., Stude, P., Kaube, H., Diener, H. C., et al. (2009). Temporal summation of trigeminal pain in human anterior cingulate cortex. Neuroimage 46, 193-200. doi: 10.1016/j.neuroimage.2009.01.038
55. Okifuji, A., Turk, D. C., and Marcus, D. A. (1999). Comparison of generalized and localized hyperalgesia in patients with recurrent headache and fibromyalgia. Psychosom. Med. 61, 771-780.
56. Panconesi, A., Bartolozzi, M. L., and Guidi, L. (2009). Migraine pain: reflections against vasodilatation. J. Headache Pain 10, 317-325. doi: 10.1007/s10194-009-0130-6
57. Peres, M. F. P., Zukerman, E., Young, W. B., and Silberstein, S. D. (2002). Fatigue in chronic migraine patients. Cephalagia 22, 720-724. doi: 10.1046/j.1468-2982.2002.00426.x
58. Pietrobon, D. (2005). Migraine: new molecular mechanisms. Neuroscientist 11, 373-386. doi: 10.1177/1073858405275554
59. Puri, B. K., Jakeman, P. M., Agour, M., Gunatilake, K. D., Fernando, K. A., Gurusinghe, A. I., et al. (2012). Regional grey and white matter volumetric changes in myalgic encephalomyelitis (chronic fatigue syndrome): a voxel-based morphometry 3 T MRI study. Br. J. Radiol. 85, e270-e273. doi: 10.1259/bjr/93889091
60. RAC-GWVI. (2008). Gulf War Illness and the Health of Gulf War Veterans. Washington, DC: U.S. Government Printing Office.
61. Ravindran, M. K., Zheng, Y., Timbol, C., Merck, S. J., and Baraniuk, J. N. (2011). Migraine headaches in chronic fatigue syndrome (CFS): comparison of two prospective cross-sectional studies. BMC Neurol. 11:30. doi: 10.1186/1471-2377-11-30
62. Rayhan, R. U., Stevens, B., Adewuyi, O., Timbol, C., VanMeter, J. W., Walitt, B., et al. (2013a). Increased brain white matter axial diffusivity is associated with pain, fatigue and hyperalgesia in Gulf War Illness. PLoS ONE 8:e58493. doi: 10.1371/journal.pone.0058493
63. Rayhan, R. U., Stevens, B. W., Raksit, M., Adewuyi, O., Ripple, J. A., Timbol, C. R., et al. (2013b). Exercise challenge in Gulf War Illness reveals two subgroups with altered brain structure and function. PLoS ONE 8:e63903. doi: 10.1371/journal.pone.0063903
64. Rayhan, R. U., Zheng, Y., Uddin, E., Timbol, C. R., Adewuyi, O., and Baraniuk, J. N. (2013c). Administer and collect medical questionnaires with Google documents: a simple, safe, and free system. Appl. Med. Inform. 32, (in press).
65. Recober, A., Kaiser, E. A., Kuburas, A., and Russo, A. F. (2010). Induction of multiple photophobic behaviors in a transgenic mouse sensitized to CGRP. Neuropharmacology 1, 156-165. doi: 10.1016/j.neuropharm.2009.07.009
66. Reeves, W. C., Lloyd, A., Vernon, S. D., Klimas, N., Jason, L. A., Bleijenberg, G., et al. (2003). International chronic fatigue syndrome study group. Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution. BMC Health Serv. Res. 3:25. doi: 10.1186/1472-6963-3-25
67. Reeves, W. C., Wagner, D., Nisenbaum, R., Jones, J. F., Gurbaxani, B., Solomon, L., et al. (2005). Chronic fatigue syndrome-a clinically empirical approach to its definition and study. BMC Med. 3:19. doi: 10.1186/1741-7015-3-19
68. Reiffenberger, D. H., and Amundson, L. H. (1996). Fibromyalgia syndrome: a review. Am. Fam. Physician 53, 1698-1712.
69. Rowbottom, D., Keast, D., Pervan, Z., Goodman, C., Bhagat, C., Kakulas, B., et al. (1998). The role of Glutamine in the aetiology of the Chronic Fatigue Syndrome: a prospective study. J. Chron. Fatigue Syndr. 2, 3-22.
70. Schürks, M., Rist, P. M., and Kurth, T. (2010). Sex hormone receptor gene polymorphisms and migraine: a systematic review and meta-analysis. Cephalalgia 11, 1306-1328. doi: 10.1177/0333102410364155
71. Schwedt, T. J., and Dodick, D. W. (2009). Advanced neuroimaging of migraine. Lancet Neurol. 8, 560-568. doi: 10.1016/S1474-442270107-3
72. Smith, J. M., Bradley, D. P., James, M. F., and Huang, C. L. (2006). Physiological studies of cortical spreading depression. Biol. Rev. Camb. Philos. Soc. 81, 457-481. doi: 10.1017/S1464793106007081
73. Steele, L., Sastre, A., Gerkovich, M. M., and Cook, M. R. (2012). Complex factors in the etiology of Gulf War illness: wartime exposures and risk factors in veteran subgroups. Environ. Health Perspect. 1, 112-118.
74. Stephen, D. (2005). Atlas of Migraine and Other Headaches. London: Taylor and Francis Group.
75. Strong, A. J., and Dardis, R. (2005). Depolarisation phenomena in traumatic and ischaemic brain injury. Adv. Tech. Stand. Neurosurg. 30, 3-49. doi: 10.1007/3-211-27208-9_1
76. Strong, A. J., Hartings, J. A., and Dreier, J. P. (2007). Cortical spreading depression: an adverse but treatable factor in intensive care. Curr. Opin. Crit. Care 13, 126-133. doi: 10.1097/MCC.0b013e32807faffb
77. Sullivan, P. F., Pedersen, N. L., Jacks, A., and Evengard, B. (2005). Chronic fatigue in a population sample: definitions and heterogeneity. Psychol. Med. 35, 1337-1348. doi: 10.1017/S0033291705005210
78. Swartz, R. H., and Kern, R. Z. (2004). Migraine is associated with magnetic resonance imaging white matter abnormalities: a meta-analysis. Arch. Neurol. 61, 1366-1368. doi: 10.1001/archneur.61.9.1366
79. Sweeting, M. J., Sutton, A. J., and Lambert, P. C. (2004). What to add to nothing. Use and avoidance of continuity corrections in meta-analysis of sparse data. Stat. Med. 9, 1351-1375. doi: 10.1002/sim.1761
80. Tietjen, G. E., Brandes, J. L., Peterlin, B. L., Eloff, A., Dafer, R. M., Stein, M. R., et al. (2009). Allodynia in migraine: association with comorbid pain conditions. Headache 9, 1333-1344. doi: 10.1111/j.1526-4610.2009.01521.x
81. Ware, J. E., and Sherbourne, C. D. (1995). The MOS 36-item short-form health survey (SF-36): I. Conceptual framework and item selection. Med. Care 30, 473-483. doi: 10.1097/00005650-199206000-199200002
82. Weill, C., May, A., and Limmroth, V. (1995). Brainstem activation in spontaneous human migraine attacks. Nat. Med. 1, 658-660. doi: 10.1038/nm0795-658.
83. Wolfe, F., Clauw, D. J., Fitzcharles, M. A., Goldenberg, D. L., Katz, R. S., Mease, P., et al. (2010). The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res. (Hoboken) 62, 600-610. doi: 10.1002/acr.20140
84. Wolfe, F., Smythe, H., Yunus, M., Bennett, R., Bombardier, C., and Goldenberg, D. (1990). The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the multicenter criteria committee. Arthritis Rheum. 33, 160-172. doi: 10.1002/art.1780330203
85. Woodward, S. H., Kaloupek, D. G., Streeter, C. C., Martinez, C., Schaer, M., and Eliez, S. (2006). Decreased anterior cingulate volume in combat-related PTSD. Biol. Psychiatry 59, 582-587. doi: 10.1016/j.biopsych.2005.07.033