메뉴 건너뛰기




Volumn 6, Issue 4, 2013, Pages 409-412

Establishing validity of pharmacogenomic findings: From replication to triangulation

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARDIOVASCULAR DISEASE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; PHARMACOGENOMICS; PHENOTYPE; PRIORITY JOURNAL; REPLICATION STUDY; TRIANGULATION; CARDIOVASCULAR DISEASES; CLINICAL COMPETENCE; GENETICS; PHARMACOGENETICS; REPRODUCIBILITY; SINGLE NUCLEOTIDE POLYMORPHISM; REVIEW;

EID: 84884511762     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.112.000010     Document Type: Article
Times cited : (23)

References (24)
  • 2
    • 11144313604 scopus 로고    scopus 로고
    • Replication in genetic studies of complex traits
    • Sillanpää MJ, Auranen K. Replication in genetic studies of complex traits. Ann Hum Genet. 2004;68(Pt 6):646-657.
    • (2004) Ann Hum Genet , vol.68 , Issue.PART 6 , pp. 646-657
    • Sillanpää, M.J.1    Auranen, K.2
  • 4
    • 77949756362 scopus 로고    scopus 로고
    • Genome-wide association studies in pharmacogenomics
    • Daly AK. Genome-wide association studies in pharmacogenomics. Nat Rev Genet. 2010;11:241-246.
    • (2010) Nat Rev Genet , vol.11 , pp. 241-246
    • Daly, A.K.1
  • 5
    • 79955492923 scopus 로고    scopus 로고
    • Pharmacogenomics: The genetics of variable drug responses
    • Roden DM, Wilke RA, Kroemer HK, Stein CM. Pharmacogenomics: the genetics of variable drug responses. Circulation. 2011;123:1661-1670.
    • (2011) Circulation , vol.123 , pp. 1661-1670
    • Roden, D.M.1    Wilke, R.A.2    Kroemer, H.K.3    Stein, C.M.4
  • 6
    • 50549083074 scopus 로고    scopus 로고
    • Curses-winner's and otherwise-in genetic epidemiology
    • discussion 657
    • Kraft P. Curses-winner's and otherwise-in genetic epidemiology. Epidemiology. 2008;19:649-651; discussion 657.
    • (2008) Epidemiology , vol.19 , pp. 649-651
    • Kraft, P.1
  • 7
    • 77953774727 scopus 로고    scopus 로고
    • Replication of past candidate loci for common diseases and phenotypes in 100 genome-wide association studies
    • Siontis KC, Patsopoulos NA, Ioannidis JP. Replication of past candidate loci for common diseases and phenotypes in 100 genome-wide association studies. Eur J Hum Genet. 2010;18:832-837.
    • (2010) Eur J Hum Genet , vol.18 , pp. 832-837
    • Siontis, K.C.1    Patsopoulos, N.A.2    Ioannidis, J.P.3
  • 8
    • 80051552041 scopus 로고    scopus 로고
    • The false-positive to false-negative ratio in epidemiologic studies
    • Ioannidis JP, Tarone R, McLaughlin JK. The false-positive to false-negative ratio in epidemiologic studies. Epidemiology. 2011;22: 450-456.
    • (2011) Epidemiology , vol.22 , pp. 450-456
    • Ioannidis, J.P.1    Tarone, R.2    McLaughlin, J.K.3
  • 9
    • 79960698030 scopus 로고    scopus 로고
    • Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of mi
    • Peters BJ, Pett H, Klungel OH, Stricker BH, Psaty BM, Glazer NL, et al. Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI. Atherosclerosis. 2011;217:458-464.
    • (2011) Atherosclerosis , vol.217 , pp. 458-464
    • Peters, B.J.1    Pett, H.2    Klungel, O.H.3    Stricker, B.H.4    Psaty, B.M.5    Glazer, N.L.6
  • 10
    • 75649087725 scopus 로고    scopus 로고
    • Effect of ace insertion/deletion and 12 other polymorphisms on clinical outcomes and response to treatment in the life study
    • N ordestgaard BG, Kontula K, Benn M, Dahlöf B, de Faire U, Edelman JM, et al. Effect of ACE insertion/deletion and 12 other polymorphisms on clinical outcomes and response to treatment in the LIFE study. Pharmacogenet Genomics. 2010;20:77-85.
    • (2010) Pharmacogenet Genomics , vol.20 , pp. 77-85
    • Nordestgaard, B.G.1    Kontula, K.2    Benn, M.3    Dahlöf, B.4    De Faire, U.5    Edelman, J.M.6
  • 11
    • 69549111453 scopus 로고    scopus 로고
    • Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the treating to new targets (tnt) cohort
    • Thompson JF, Hyde CL, Wood LS, Paciga SA, Hinds DA, Cox DR, et al. Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohort. Circ Cardiovasc Genet. 2009;2:173-181.
    • (2009) Circ Cardiovasc Genet , vol.2 , pp. 173-181
    • Thompson, J.F.1    Hyde, C.L.2    Wood, L.S.3    Paciga, S.A.4    Hinds, D.A.5    Cox, D.R.6
  • 14
    • 67651196989 scopus 로고    scopus 로고
    • Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response
    • V oora D, Shah SH, Reed CR, Zhai J, Crosslin DR, Messer C, et al. Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response. Circ Cardiovasc Genet. 2008;1: 100-106.
    • (2008) Circ Cardiovasc Genet , vol.1 , pp. 100-106
    • Voora, D.1    Shah, S.H.2    Reed, C.R.3    Zhai, J.4    Crosslin, D.R.5    Messer, C.6
  • 15
    • 66849097781 scopus 로고    scopus 로고
    • Failure to replicate a genetic association may provide important clues about genetic architecture
    • Greene CS, Penrod NM, Williams SM, Moore JH. Failure to replicate a genetic association may provide important clues about genetic architecture. PLoS One. 2009;4:e5639.
    • (2009) PLoS One , vol.4
    • Greene, C.S.1    Penrod, N.M.2    Williams, S.M.3    Moore, J.H.4
  • 17
    • 69549124105 scopus 로고    scopus 로고
    • Drug-sensitized zebrafish screen identifies multiple genes, including gins3, as regulators of myocardial repolarization
    • Milan DJ, Kim AM, Winterfield JR, Jones IL, Pfeufer A, Sanna S, et al. Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Circulation. 2009;120:553-559.
    • (2009) Circulation , vol.120 , pp. 553-559
    • Milan, D.J.1    Kim, A.M.2    Winterfield, J.R.3    Jones, I.L.4    Pfeufer, A.5    Sanna, S.6
  • 18
    • 49149095635 scopus 로고    scopus 로고
    • Alternative splicing of 3-hydroxy-3-methylglutaryl coenzyme a reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin
    • Medina MW, Gao F, Ruan W, Rotter JI, Krauss RM. Alternative splicing of 3-hydroxy-3-methylglutaryl coenzyme A reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin. Circulation. 2008;118:355-362.
    • (2008) Circulation , vol.118 , pp. 355-362
    • Medina, M.W.1    Gao, F.2    Ruan, W.3    Rotter, J.I.4    Krauss, R.M.5
  • 19
    • 31744435871 scopus 로고    scopus 로고
    • Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
    • Skol AD, Scott LJ, Abecasis GR, Boehnke M. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet. 2006;38:209-213.
    • (2006) Nat Genet , vol.38 , pp. 209-213
    • Skol, A.D.1    Scott, L.J.2    Abecasis, G.R.3    Boehnke, M.4
  • 20
    • 38949210321 scopus 로고    scopus 로고
    • Methods for meta-Analysis in genetic association studies: A review of their potential and pitfalls
    • Kavvoura FK, Ioannidis JP. Methods for meta-Analysis in genetic association studies: a review of their potential and pitfalls. Hum Genet. 2008;123:1-14.
    • (2008) Hum Genet , vol.123 , pp. 1-14
    • Kavvoura, F.K.1    Ioannidis, J.P.2
  • 22
    • 50549104769 scopus 로고    scopus 로고
    • Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of parkinson's disease
    • Li Y, Rowland C, Xiromerisiou G, Lagier RJ, Schrodi SJ, Dradiotis E, et al. Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease. PLoS One. 2008;3:e2707.
    • (2008) PLoS One , vol.3
    • Li, Y.1    Rowland, C.2    Xiromerisiou, G.3    Lagier, R.J.4    Schrodi, S.J.5    Dradiotis, E.6
  • 23
    • 77449140764 scopus 로고    scopus 로고
    • Gene and pathwaybased second-wave analysis of genome-wide association studies
    • Peng G, Luo L, Siu H, Zhu Y, Hu P, Hong S, et al. Gene and pathwaybased second-wave analysis of genome-wide association studies. Eur J Hum Genet. 2010;18:111-117.
    • (2010) Eur J Hum Genet , vol.18 , pp. 111-117
    • Peng, G.1    Luo, L.2    Siu, H.3    Zhu, Y.4    Hu, P.5    Hong, S.6
  • 24
    • 61449230785 scopus 로고    scopus 로고
    • Interpretation of genetic association studies: Markers with replicated highly significant odds ratios may be poor classifiers
    • Jakobsdottir J, Gorin MB, Conley YP, Ferrell RE, Weeks DE. Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers. PLoS Genet. 2009;5:e1000337.
    • (2009) PLoS Genet , vol.5
    • Jakobsdottir, J.1    Gorin, M.B.2    Conley, Y.P.3    Ferrell, R.E.4    Weeks, D.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.