메뉴 건너뛰기




Volumn 217, Issue 2, 2011, Pages 458-464

Genetic variability within the cholesterol lowering pathway and the effectiveness of statins in reducing the risk of MI

Author keywords

Case control study; Cholesterol; Myocardial infarction; PCSK9; Pharmacogenetics; SCARB1; Statin

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

EID: 79960698030     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.06.023     Document Type: Article
Times cited : (41)

References (31)
  • 1
    • 2342468034 scopus 로고    scopus 로고
    • Meta-analysis of large randomized controlled trials to evaluate the impact of statins on cardiovascular outcomes
    • Cheung B.M., Lauder I.J., Lau C.P., Kumana C.R. Meta-analysis of large randomized controlled trials to evaluate the impact of statins on cardiovascular outcomes. Br J Clin Pharmacol 2004, 57(5):640-651.
    • (2004) Br J Clin Pharmacol , vol.57 , Issue.5 , pp. 640-651
    • Cheung, B.M.1    Lauder, I.J.2    Lau, C.P.3    Kumana, C.R.4
  • 3
    • 58849165389 scopus 로고    scopus 로고
    • Interaction between the Gly460Trp alpha-adducin gene variant and diuretics on the risk of myocardial infarction
    • van Wieren-de Wijer D.B., Maitland-van der Zee A.H., de Boer A., et al. Interaction between the Gly460Trp alpha-adducin gene variant and diuretics on the risk of myocardial infarction. J Hypertens 2009, 27(1):61-68.
    • (2009) J Hypertens , vol.27 , Issue.1 , pp. 61-68
    • van Wieren-de Wijer, D.B.1    Maitland-van der Zee, A.H.2    de Boer, A.3
  • 4
    • 77955631252 scopus 로고    scopus 로고
    • Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction
    • Peters B.J.M., Rodin A.S., Klungel O.H., et al. Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction. Pharmacogenomics 2010, 11(8):1065-1076.
    • (2010) Pharmacogenomics , vol.11 , Issue.8 , pp. 1065-1076
    • Peters, B.J.M.1    Rodin, A.S.2    Klungel, O.H.3
  • 5
    • 63049130363 scopus 로고    scopus 로고
    • Recruitment of participants through community pharmacies for a pharmacogenetic study of antihypertensive drug treatment
    • van Wieren-de Wijer D.B., Maitland-van der Zee A.H., de Boer A., et al. Recruitment of participants through community pharmacies for a pharmacogenetic study of antihypertensive drug treatment. Pharm World Sci 2009, 31(2):158-164.
    • (2009) Pharm World Sci , vol.31 , Issue.2 , pp. 158-164
    • van Wieren-de Wijer, D.B.1    Maitland-van der Zee, A.H.2    de Boer, A.3
  • 6
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • Frazer K.A., Ballinger D.G., Cox D.R., et al. A second generation human haplotype map of over 3.1 million SNPs. Nature 2007, 449(7164):851-861.
    • (2007) Nature , vol.449 , Issue.7164 , pp. 851-861
    • Frazer, K.A.1    Ballinger, D.G.2    Cox, D.R.3
  • 7
    • 34547590995 scopus 로고    scopus 로고
    • QuickSNP: an automated web server for selection of tagSNPs
    • Web Server issue
    • Grover D., Woodfield A.S., Verma R., et al. QuickSNP: an automated web server for selection of tagSNPs. Nucleic Acids Res 2007, 35(Web Server issue):W115-W120.
    • (2007) Nucleic Acids Res , vol.35
    • Grover, D.1    Woodfield, A.S.2    Verma, R.3
  • 8
    • 0035173378 scopus 로고    scopus 로고
    • DbSNP: the NCBI database of genetic variation
    • Sherry S.T., Ward M.H., Kholodov M., et al. dbSNP: the NCBI database of genetic variation. Nucleic Acids Res 2001, 29(1):308-311.
    • (2001) Nucleic Acids Res , vol.29 , Issue.1 , pp. 308-311
    • Sherry, S.T.1    Ward, M.H.2    Kholodov, M.3
  • 9
    • 0028237283 scopus 로고
    • The risk of myocardial infarction associated with the combined use of estrogens and progestins in postmenopausal women
    • Psaty B.M., Heckbert S.R., Atkins D., et al. The risk of myocardial infarction associated with the combined use of estrogens and progestins in postmenopausal women. Arch Intern Med 1994, 154(12):1333-1339.
    • (1994) Arch Intern Med , vol.154 , Issue.12 , pp. 1333-1339
    • Psaty, B.M.1    Heckbert, S.R.2    Atkins, D.3
  • 10
    • 0029161079 scopus 로고
    • The risk of myocardial infarction associated with antihypertensive drug therapies
    • Psaty B.M., Heckbert S.R., Koepsell T.D., et al. The risk of myocardial infarction associated with antihypertensive drug therapies. JAMA 1995, 274(8):620-625.
    • (1995) JAMA , vol.274 , Issue.8 , pp. 620-625
    • Psaty, B.M.1    Heckbert, S.R.2    Koepsell, T.D.3
  • 11
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey J.D., Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003, 100(16):9440-9445.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.16 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 12
    • 77950458892 scopus 로고    scopus 로고
    • Influence of SCARB1 polymorphisms on serum lipids of hypercholesterolemic individuals treated with atorvastatin
    • Cerda A., Genvigir F.D., Arazi S.S., et al. Influence of SCARB1 polymorphisms on serum lipids of hypercholesterolemic individuals treated with atorvastatin. Clin Chim Acta 2010, 411(9-10):631-637.
    • (2010) Clin Chim Acta , vol.411 , Issue.9-10 , pp. 631-637
    • Cerda, A.1    Genvigir, F.D.2    Arazi, S.S.3
  • 13
    • 0037603589 scopus 로고    scopus 로고
    • Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
    • Abifadel M., Varret M., Rabes J.P., et al. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat Genet 2003, 34(2):154-156.
    • (2003) Nat Genet , vol.34 , Issue.2 , pp. 154-156
    • Abifadel, M.1    Varret, M.2    Rabes, J.P.3
  • 14
    • 33846679386 scopus 로고    scopus 로고
    • Molecular biology of PCSK9: its role in LDL metabolism
    • Horton J.D., Cohen J.C., Hobbs H.H. Molecular biology of PCSK9: its role in LDL metabolism. Trends Biochem Sci 2007, 32(2):71-77.
    • (2007) Trends Biochem Sci , vol.32 , Issue.2 , pp. 71-77
    • Horton, J.D.1    Cohen, J.C.2    Hobbs, H.H.3
  • 15
    • 33645103550 scopus 로고    scopus 로고
    • Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
    • Cohen J.C., Boerwinkle E., Mosley T.H., Hobbs H.H. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med 2006, 354(12):1264-1272.
    • (2006) N Engl J Med , vol.354 , Issue.12 , pp. 1264-1272
    • Cohen, J.C.1    Boerwinkle, E.2    Mosley, T.H.3    Hobbs, H.H.4
  • 16
    • 33748601835 scopus 로고    scopus 로고
    • The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women
    • Evans D., Beil F.U. The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women. BMC Med Genet 2006, 7:66.
    • (2006) BMC Med Genet , vol.7 , pp. 66
    • Evans, D.1    Beil, F.U.2
  • 17
    • 59849087105 scopus 로고    scopus 로고
    • The PCSK9 gene E670G polymorphism affects low-density lipoprotein cholesterol levels but is not a risk factor for coronary artery disease in ethnic Chinese in Taiwan
    • Hsu L.A., Teng M.S., Ko Y.L., et al. The PCSK9 gene E670G polymorphism affects low-density lipoprotein cholesterol levels but is not a risk factor for coronary artery disease in ethnic Chinese in Taiwan. Clin Chem Lab Med 2009, 47(2):154-158.
    • (2009) Clin Chem Lab Med , vol.47 , Issue.2 , pp. 154-158
    • Hsu, L.A.1    Teng, M.S.2    Ko, Y.L.3
  • 18
    • 73449143804 scopus 로고    scopus 로고
    • Effects of PCSK9 variants on common carotid artery intima media thickness and relation to ApoE alleles
    • Norata G.D., Garlaschelli K., Grigore L., et al. Effects of PCSK9 variants on common carotid artery intima media thickness and relation to ApoE alleles. Atherosclerosis 2008, 208(1):177-182.
    • (2008) Atherosclerosis , vol.208 , Issue.1 , pp. 177-182
    • Norata, G.D.1    Garlaschelli, K.2    Grigore, L.3
  • 19
    • 18944392912 scopus 로고    scopus 로고
    • A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis
    • Chen S.N., Ballantyne C.M., Gotto A.M., et al. A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis. J Am Coll Cardiol 2005, 45(10):1611-1619.
    • (2005) J Am Coll Cardiol , vol.45 , Issue.10 , pp. 1611-1619
    • Chen, S.N.1    Ballantyne, C.M.2    Gotto, A.M.3
  • 20
    • 33344464808 scopus 로고    scopus 로고
    • A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol
    • Kotowski I.K., Pertsemlidis A., Luke A., et al. A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol. Am J Hum Genet 2006, 78(3):410-422.
    • (2006) Am J Hum Genet , vol.78 , Issue.3 , pp. 410-422
    • Kotowski, I.K.1    Pertsemlidis, A.2    Luke, A.3
  • 21
    • 49949100564 scopus 로고    scopus 로고
    • Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population
    • Polisecki E., Peter I., Robertson M., et al. Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population. Atherosclerosis 2008, 200(1):95-101.
    • (2008) Atherosclerosis , vol.200 , Issue.1 , pp. 95-101
    • Polisecki, E.1    Peter, I.2    Robertson, M.3
  • 22
    • 36849085368 scopus 로고    scopus 로고
    • The PCSK9 gene R46L variant is associated with lower plasma lipid levels and cardiovascular risk in healthy U.K. men
    • Scartezini M., Hubbart C., Whittall R.A., et al. The PCSK9 gene R46L variant is associated with lower plasma lipid levels and cardiovascular risk in healthy U.K. men. Clin Sci (Lond) 2007, 113(11):435-441.
    • (2007) Clin Sci (Lond) , vol.113 , Issue.11 , pp. 435-441
    • Scartezini, M.1    Hubbart, C.2    Whittall, R.A.3
  • 23
    • 33646443979 scopus 로고    scopus 로고
    • Missense mutations in the PCSK9 gene are associated with hypocholesterolemia and possibly increased response to statin therapy
    • Berge K.E., Ose L., Leren T.P. Missense mutations in the PCSK9 gene are associated with hypocholesterolemia and possibly increased response to statin therapy. Arterioscler Thromb Vasc Biol 2006, 26(5):1094-1100.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , Issue.5 , pp. 1094-1100
    • Berge, K.E.1    Ose, L.2    Leren, T.P.3
  • 24
    • 33749025102 scopus 로고    scopus 로고
    • Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk
    • Humphries S.E., Whittall R.A., Hubbart C.S., et al. Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk. J Med Genet 2006, 43(12):943-949.
    • (2006) J Med Genet , vol.43 , Issue.12 , pp. 943-949
    • Humphries, S.E.1    Whittall, R.A.2    Hubbart, C.S.3
  • 25
    • 33644807009 scopus 로고    scopus 로고
    • Severe hypercholesterolemia in four British families with the D374Y mutation in the PCSK9 gene: long-term follow-up and treatment response
    • Naoumova R.P., Tosi I., Patel D., et al. Severe hypercholesterolemia in four British families with the D374Y mutation in the PCSK9 gene: long-term follow-up and treatment response. Arterioscler Thromb Vasc Biol 2005, 25(12):2654-2660.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.12 , pp. 2654-2660
    • Naoumova, R.P.1    Tosi, I.2    Patel, D.3
  • 26
    • 69549111453 scopus 로고    scopus 로고
    • Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohort
    • Thompson J.F., Hyde C.L., Wood L.S., et al. Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohort. Circ Cardiovasc Genet 2009, 2(2):173-181.
    • (2009) Circ Cardiovasc Genet , vol.2 , Issue.2 , pp. 173-181
    • Thompson, J.F.1    Hyde, C.L.2    Wood, L.S.3
  • 27
    • 0242668381 scopus 로고    scopus 로고
    • Hepatic lipase: a marker for cardiovascular disease risk and response to therapy
    • Zambon A., Deeb S.S., Pauletto P., Crepaldi G., Brunzell J.D. Hepatic lipase: a marker for cardiovascular disease risk and response to therapy. Curr Opin Lipidol 2003, 14(2):179-189.
    • (2003) Curr Opin Lipidol , vol.14 , Issue.2 , pp. 179-189
    • Zambon, A.1    Deeb, S.S.2    Pauletto, P.3    Crepaldi, G.4    Brunzell, J.D.5
  • 28
    • 0032032592 scopus 로고    scopus 로고
    • Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study)
    • Jones P., Kafonek S., Laurora I., Hunninghake D. Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study). Am J Cardiol 1998, 81(5):582-587.
    • (1998) Am J Cardiol , vol.81 , Issue.5 , pp. 582-587
    • Jones, P.1    Kafonek, S.2    Laurora, I.3    Hunninghake, D.4
  • 29
    • 0036805674 scopus 로고    scopus 로고
    • Statins as anti-inflammatory agents
    • Weitz-Schmidt G. Statins as anti-inflammatory agents. Trends Pharmacol Sci 2002, 23(10):482-486.
    • (2002) Trends Pharmacol Sci , vol.23 , Issue.10 , pp. 482-486
    • Weitz-Schmidt, G.1
  • 30
    • 0031010532 scopus 로고    scopus 로고
    • Validation of pharmacy records in drug exposure assessment
    • Lau H.S., de Boer A., Beuning K.S., Porsius A. Validation of pharmacy records in drug exposure assessment. J Clin Epidemiol 1997, 50(5):619-625.
    • (1997) J Clin Epidemiol , vol.50 , Issue.5 , pp. 619-625
    • Lau, H.S.1    de Boer, A.2    Beuning, K.S.3    Porsius, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.